CN104069210B - A kind of Chinese medicine for the treatment of senile dementia and preparation method thereof - Google Patents
A kind of Chinese medicine for the treatment of senile dementia and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to technical field of Chinese medicines, particularly a kind of Chinese medicine for the treatment of senile dementia and preparation method thereof.The Chinese medicine of this treatment senile dementia, the crude drug primarily of following weight is made: Olibanum 5-15g, Herba Asari 1-3g, Fructus Toosendan 7-15g, Radix Angelicae Dahuricae 3-12g, Radix Achyranthis Bidentatae 5-15g, Scolopendra 3-5g, Scorpio 5-10g, hippocampus 3-10g, Radix Puerariae 15-25g, Poria 10-15g, succinum 2-5g, Caulis Polygoni Multiflori 2-4g, Folium Mori 5-10g, Ramulus Uncariae Cum Uncis 6-10g, Borneolum Syntheticum 0.5g, Styrax 0.3-1g, Cordyceps 3-9g, Folium Nelumbinis 3-6g.The invention has the beneficial effects as follows: above-mentioned all medicine compatibilities, can blood circulation promoting and blood stasis dispelling, liver heat removing relieve dizziness, high fever, infantile convulsions, epilepsy, etc., removing obstruction in the collateral to relieve pain, to treatment senile dementia, there is the effect for the treatment of both the principal and secondary aspects of a disease.Chinese medicine of the present invention focuses on and effects a permanent cure, and drug effect is fast, good effect, and effective percentage is up to 95.7%.
Description
(1) technical field
The present invention relates to technical field of Chinese medicines, particularly a kind of Chinese medicine for the treatment of senile dementia and preparation method thereof.
(2) background technology
Senile dementia is the nervous system degenerative disease of the Progressive symmetric erythrokeratodermia development of a kind of onset concealment.Show as feature with dysmnesia, aphasia, apraxia, agnosia, the infringement of visual space technical ability, n-back test obstacle and the generalized dementia such as personality and behavior change clinically, the cause of disease is not bright so far.The medicine of current treatment senile dementia generally has acetylcholine precursor thing, lecithin, trifluoperazine etc., and side effect is obvious, needs to improve.The Chinese medicine of the treatment senile dementia of present announcement, all has certain curative effect, but the cycle of most Drug therapy is long.
(3) summary of the invention
The present invention, in order to make up the deficiencies in the prior art, provides Chinese medicine of a kind for the treatment of senile dementia of effective, short treating period and preparation method thereof.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine for senile dementia, its special character is: the crude drug primarily of following weight is made:
Olibanum 5-15g, Herba Asari 1-3g, Fructus Toosendan 7-15g, Radix Angelicae Dahuricae 3-12g, Radix Achyranthis Bidentatae 5-15g, Scolopendra 3-5g, Scorpio 5-10g, hippocampus 3-10g, Radix Puerariae 15-25g, Cortex Magnoliae Officinalis 3-10g, Poria 10-15g, succinum 2-5g, Caulis Polygoni Multiflori 2-4g, Folium Mori 5-10g, Ramulus Uncariae Cum Uncis 6-10g, Borneolum Syntheticum 0.5g, Styrax 0.3-1g, Cordyceps 3-9g, Folium Nelumbinis 3-6g.
The preparation method of the Chinese medicine for the treatment of senile dementia of the present invention, also comprises Folium ilicis serratae 10-15g, Herba Ophioglossi 10-15g, Radix onosmatis 10-15g.
The preparation method of the Chinese medicine for the treatment of senile dementia of the present invention, comprises the following steps: by crude drug soak by water, take.
Instructions of taking: every day potion, morning and evening service once 1 month is a course for the treatment of.
Be the function and effect of each medical material in the present invention below:
Olibanum: nature and flavor: arduous, temperature.Gui Jing: enter the heart, liver, spleen channel.Cure mainly: regulating qi and activating blood, analgesic therapy, chase after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Herba Asari: nature and flavor: acrid in the mouth; Warm in nature; Mild toxicity.Gui Jing: lung meridian, kidney channel, heart channel, Liver Channel, gallbladder meridian, spleen channel.Effect: eliminate suppurative mastitis inflammation; Mass dissipating and swelling eliminating; Induce sweat cold expelling; Wind-expelling pain-stopping; Warming the lung to resolve fluid-retention; The therapeutic method to keep the adverse QI flowing downwards is eliminated the phlegm, sensible.Cure mainly: mastalgia swells; Cold expelling dispels the wind; Pain relieving; Warming the lung to resolve fluid-retention; Sensible.Exterior syndrome due to wind-cold; Headache, toothache; Rheumatic arthralgia; Phlegm retention cough with asthma; Nasal obstruction; Nasal sinusitis; Aphtha.For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.
Fructus Toosendan: nature and flavor: bitter, cold, poisonous.Gui Jing: enter liver, stomach, small intestine meridian.Function cures mainly: except damp and hot, clearing away liver-fire, pain relieving, parasite killing.Control epigastric pain with cold limbs due to adverseness of heat, hypochondriac pain, colic, abdominal pain due to worm stagnation.
The Radix Angelicae Dahuricae: nature and flavor: pungent, temperature.Gui Jing: enter lung, spleen, stomach warp.For Yangming Channel guiding drug.Attending effectiveness: expelling wind and removing dampness; Logical surreptitiously pain relieving; Detumescence and apocenosis.Main headache due to common cold; Supraorbital bone pain; Toothache; Nasal obstruction; Nasal sinusitis; Domination of damp pathogen chronic diarrhea; Women leucorrhea; Ulcer sores; Venom.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.Effect: expelling wind and cold, understand things pain-stopping, evacuation of pus of invigorating blood circulation, granulation promoting pain relieving, dampness leukorrhagia stopping.
Radix Achyranthis Bidentatae: nature and flavor: bitter; Acid; Property is put down.Gui Jing: liver; Kidney channel.Effect: invigorating the liver and kidney; Bone and muscle strengthening; Promoting blood circulation to restore menstrual flow; Ignite (blood) descending; Inducing diuresis for treating stranguria syndrome.Cure mainly: soreness of waist and knee joint; Flaccidity and weakness of the lower limbs; Amenorrhea due to stagnation of blood; Dysmenorrhea; Puerperal abdominal pain due to blood stasis; Lump in the abdomen; Retention of placenta; Pyretic stranguria; Stranguria with blood; Traumatic injury; Carbuncle malignant boil; Laryngopharynx swelling and pain.
Scolopendra: nature and flavor: pungent, temperature; Poisonous.Gui Jing: return Liver Channel.Function cures mainly: endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom.
Scorpio: character: meridian distribution of property and flavor: pungent, flat; Poisonous.Return Liver Channel.Effect: endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.Main syndrome: for infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.
Hippocampus: nature and flavor: Gan Wen.Function: kidney invigorating and YANG supporting, eliminating mass abdominal mass.Cure mainly: to suffer from a deficiency of the kidney, the disease such as lump in the abdomen, furuncle swelling toxin.
Radix Puerariae: nature and flavor: Gan Xin is flat.Gui Jing: enter spleen, stomach warp.Function cures mainly: yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, and relieving restlessness is temperature only.Cure the wound cold, warm headache stiffness of the nape, and dysphoria with smothery sensation is quenched one's thirst, and has loose bowels, dysentery, and skin eruption is not saturating, hypertension, and angina pectoris is deaf.
Cortex Magnoliae Officinalis: nature and flavor: bitter; Pungent; Warm in nature.Gui Jing: spleen channel; Stomach warp; Large intestine channel.Function: circulation of qi promoting removing food stagnancy; Dampness is except full; Lowering the adverse QI to relieve asthma.Cure mainly: stagnation of QI due to dyspepsia; Abdominal distention constipation; Retention of dampness in middle-JIAO, gastral cavity painful abdominal mass is vomited and diarrhoea; Expectorant stops up QI rising in reverse order; Fullness in the chest is breathed with cough.
Poria: meridian distribution of property and flavor: sweet; Light; Flat.The heart; Spleen; Lung; Kidney channel.Effect: eliminating dampness and diuresis; Invigorating the spleen and regulating the stomach; Mind tranquilizing and the heart calming.For dysuria; Edema distension; Phlegm retention cough with dyspnea; Vomiting; Insufficiency of the spleen lack of appetite; Have loose bowels; Palpitation and restlessness; Insomnia forgetfulness; Seminal emission nebulousurine.
Succinum: meridian distribution of property and flavor: sweet is flat.Function cures mainly: calm, diuresis, invigorates blood circulation.For infantile convulsion, epilepsy, cardiopalmus, insomnia, dysuria, dysurea, hematuria, amenorrhea.
Caulis Polygoni Multiflori: meridian distribution of property and flavor: sweet micro-hardship is flat.Effect: nourish heart, calms the nerves, and dredging collateral dispels the wind.Cure mainly: control insomnia, impairment caused by overstrain, hyperhidrosis, blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies.
Folium Mori: bitter in the mouth, sweet, cold in nature, return lung Liver Channel.Dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.For anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted
Ramulus Uncariae Cum Uncis: nature and flavor: sweetness and bitterness; Be slightly cold.Gui Jing: Liver Channel, heart channel.Function: heat clearing away suppressing the hyperactive liver; Relieving spasm by subduing liver-wind.Cure mainly: infantile convulsion; Night cry; Intenseness of heat wind symptom; Eclamposia; Dizziness due to hyperactivity of liver-YANG; Liver-fire distending pain in the head.
Borneolum Syntheticum: have another name called sheet brain, Fructus Citri tangerinae sheet, Borneolum Syntheticum, MEIHUA BINGPIAN, Dipterocarpus pilosus, Flos Mume brain, Borneolum Syntheticum brain, Mei Bing etc., being that resin and the volatile oil processed goods of Spore density Borneolum Syntheticum extracts the crystallization obtained, is near pure dextro Borneolum Syntheticum.Also having and chemically synthesize, generating Camphora with being very easily oxidized to ketone.Multiple ter penoids is contained in the resin of Borneolum Syntheticum and volatile oil.It can be used for excess syndrome of stroke coma, for conjunctival congestion and swelling pain, sore throat aphtha, to swell and ache for skin infection, does not hold back after bursting.
Styrax: nature and flavor and function pungent, temperature.GUIXIN, spleen channel.Having one's ideas straightened out, it is dirty to ward off, eliminating phlegm pain relieving.For apoplexy syncope due to accumulation of phlegm, infantile convulsion, breast abdomen cold type of pain, angina pectoris, scabies, chilblain.
Cordyceps: warm in nature, sweet in the mouth, has the effect of the kidney invigorating and tonifying the lung, and be a kind of rare medicinal herbs of flat nourishing YIN sun, its effect is mainly derived from cordycepin, cordycepin energy liver and kidney tonifying.As " Bencao Congxin " says that it " protects lung kidney tonifying." " property of medicine is examined " also cloud: " the secret lean gas of Cordyceps, specially mends the gate of vitality." " the little knowledge in Citrus chachiensis Hort. garden " also say: " eat it with steeping in wine number piece, control pain between waist knee joint, have the merit of kidney tonifying." although Cordyceps is the little strengthening by means of tonics Chinese medicine of a kind of side effect, person is few to be directly used in prescription.All person who suffer from deficiency of kidney Yang are the most suitable coordinates meat as pig lean meat, Carnis Gallus domesticus or duck meat with Cordyceps, and even fresh human placenta etc. are stewed altogether, become tonification food, more useful.
Folium Nelumbinis: property is put down, bitter and puckery flavor.Pharmacy man of the Ming Dynasty thinks that Folium Nelumbinis can " arresting seminal emission liquid ".Also cloud in " herbal diagram ": " Folium Nelumbinis hemostasis controlling nocturnal emission with astringent drugs." " modern Practical Chinese medicinal " year: Folium Nelumbinis " for man's seminal emission or nocturia card ".The experience that China Medicine University Ye Juquan teaches is, emission: 30 grams, Folium Nelumbinis is ground into powder, often takes 3 grams, and every day each 1 time sooner or later, hot rice water takes, Qing Zheyi, two material, and severe one three material more.
Folium ilicis serratae: nature and flavor with return through sweet, bitter, cold.Function with cure mainly: heat-clearing and toxic substances removing, cooling blood for hemostasis.For burn and scald, wound hemorrhage, furuncle ulcer, lung abscess.
Herba Ophioglossi: the property of medicine; Hardship, sweet, be slightly cold, return Liver Channel, usage and consumption: heat reliving and toxin-eliminating, blood circulation promoting and blood stasis dispelling, cure mainly pain swollen, venom, scald, traumatic injury etc.
Radix onosmatis: nature and flavor: sweet is cool.Function with cure mainly: clearing away heat and cooling blood, support lung. for pneumonia, tuberculous cavity, high mountain plethora.
The invention has the beneficial effects as follows: Olibanum, Herba Asari, Fructus Toosendan, the Radix Angelicae Dahuricae, Radix Achyranthis Bidentatae removing obstruction in the collateral to relieve pain, Scolopendra, Scorpio relieve dizziness, high fever, infantile convulsions, epilepsy, etc. analgesia, Hippocampus, Radix Puerariae relieving restlessness only temperature, Cortex Magnoliae Officinalis, Poria activating QI to alleviate the depression, succinum, Caulis Polygoni Multiflori tranquillizing and allaying excitement, Folium Mori, Ramulus Uncariae Cum Uncis suppressing the hyperactive liver are flame-out, Borneolum Syntheticum, Styrax inducing resuscitation, Cordyceps, Folium Nelumbinis kidney tonifying marrow facilitating, above-mentioned all medicine compatibilities, energy blood circulation promoting and blood stasis dispelling, liver heat removing relieve dizziness, high fever, infantile convulsions, epilepsy, etc., removing obstruction in the collateral to relieve pain, inducing resuscitation, to treatment senile dementia, there is the effect for the treatment of both the principal and secondary aspects of a disease.Chinese medicine of the present invention focuses on and effects a permanent cure, and the advantages such as drug effect is fast, good effect, effective percentage is up to 95.7%.
(4) detailed description of the invention
Embodiment 1
Prescription: Olibanum 5g, Herba Asari 1g, Fructus Toosendan 7g, Radix Angelicae Dahuricae 3g, Radix Achyranthis Bidentatae 5g, Scolopendra 3g, Scorpio 5g, hippocampus 3 g, Radix Puerariae 15g, Cortex Magnoliae Officinalis 3g, Poria 10g, succinum 2g, Caulis Polygoni Multiflori 3g, Folium Mori 5g, Ramulus Uncariae Cum Uncis 8g, Borneolum Syntheticum 0.5g, Styrax 0.3g, Cordyceps 3g, Folium Nelumbinis 3g.
Preparation technology: the soak by water 3 times recipe quantity medical material being added its heavy 8 times amount, collecting decoction, takes.Every day potion, morning and evening service once, 1 month course for the treatment of.
Embodiment 2
Prescription: Olibanum 15g, Herba Asari 3g, Fructus Toosendan 15g, Radix Angelicae Dahuricae 12g, Radix Achyranthis Bidentatae 15g, Scolopendra 5g, Scorpio 10g, Hippocampus 10g, Radix Puerariae 25g, Cortex Magnoliae Officinalis 10g, Poria 15g, succinum 5g, Caulis Polygoni Multiflori 2g, Folium Mori 10g, Ramulus Uncariae Cum Uncis 6g, Borneolum Syntheticum 0.5g, Styrax 0.7g, Cordyceps 6g, Folium Nelumbinis 4gg.
Preparation technology: the soak by water 3 times recipe quantity medical material being added its heavy 8 times amount, collecting decoction, takes.Every day potion, morning and evening service once, 1 month course for the treatment of.
Embodiment 3
Prescription: Olibanum 10g, Herba Asari 2g, Fructus Toosendan 10g, Radix Angelicae Dahuricae 8g, Radix Achyranthis Bidentatae 10g, Scolopendra 4g, Scorpio 7g, Hippocampus 6g, Radix Puerariae 20g, Cortex Magnoliae Officinalis 7g, Poria 12g, succinum 4g, Caulis Polygoni Multiflori 4g, Folium Mori 6g, Ramulus Uncariae Cum Uncis 10g, Borneolum Syntheticum 0.5g, Styrax 1g, Cordyceps 9g, Folium Nelumbinis 6g.
Preparation technology: the soak by water 3 times recipe quantity medical material being added its heavy 8 times amount, collecting decoction, takes.Every day potion, morning and evening service once, 1 month course for the treatment of.
Embodiment 4
Prescription: Olibanum 5g, Herba Asari 3g, Fructus Toosendan 15g, Radix Angelicae Dahuricae 10g, Radix Achyranthis Bidentatae 10g, Scolopendra 4g, Scorpio 10g, Hippocampus 7g, Radix Puerariae 15g, Cortex Magnoliae Officinalis 3g, Poria 10g, succinum 4g, Caulis Polygoni Multiflori 4g, Folium Mori 5g, Ramulus Uncariae Cum Uncis 8g, Folium ilicis serratae 10-15g, Herba Ophioglossi 10-15g, Radix onosmatis 1210-15g, Borneolum Syntheticum 0.5g, Styrax 0.3g, Cordyceps 3g, Folium Nelumbinis 3g.
Preparation technology: the soak by water 3 times recipe quantity medical material being added its heavy 8 times amount, collecting decoction, takes.Every day potion, morning and evening service once, 1 month course for the treatment of.
Embodiment 5
Prescription: Olibanum 9g, Herba Asari 5g, Fructus Toosendan 15g, Radix Angelicae Dahuricae 10g, Radix Achyranthis Bidentatae 10g, Scolopendra 4g, Scorpio 10g, Hippocampus 7g, Radix Puerariae 15g, Cortex Magnoliae Officinalis 3g, Poria 10g, succinum 4g, Caulis Polygoni Multiflori 4g, Folium Mori 5g, Ramulus Uncariae Cum Uncis: 8g, Folium ilicis serratae 15g, Herba Ophioglossi 10g, Radix onosmatis 10g, Borneolum Syntheticum 0.5g, Styrax 0.7g, Cordyceps 6g, Folium Nelumbinis 4gg.
Preparation technology: the soak by water 3 times recipe quantity medical material being added its heavy 8 times amount, collecting decoction, takes.Every day potion, morning and evening service once, 1 month course for the treatment of.
Embodiment 6
Prescription: Olibanum 15g, Herba Asari 3g, Fructus Toosendan 10g, Radix Angelicae Dahuricae 10g, Radix Achyranthis Bidentatae 10g, Scolopendra 4g, Scorpio 10g, Hippocampus 7g, Radix Puerariae 15g, Cortex Magnoliae Officinalis 3g, Poria 10g, succinum 4g, Caulis Polygoni Multiflori 4g, Folium Mori 5g, Ramulus Uncariae Cum Uncis: 8g, Folium ilicis serratae 12g, Herba Ophioglossi 12g, Radix onosmatis 15g, Borneolum Syntheticum 0.5g, Styrax 1g, Cordyceps 9g, Folium Nelumbinis 6g.
Preparation technology: the soak by water 3 times recipe quantity medical material being added its heavy 8 times amount, collecting decoction, takes.Every day potion, morning and evening service once, 1 month course for the treatment of.
Embodiment 7 clinical observation
(1) physical data
The present inventor carried out clinical observation treatment to 300 routine cancer patients so far in 2000, and 60 to 80 years old ages, not etc. the course of disease 1 year-3 years was not etc.
(2) Therapeutic Method: every day potion, morning and evening service once, 1 month course for the treatment of.
(3) efficacy assessment standard
Cure: symptom and sign disappears completely;
Effective: symptom and sign comparatively before alleviates;
Invalid: symptom and sign is front without improving with treatment.
(5) therapeutic effect:
Clinical cure 265 example, accounts for 88.3%; Effective 22 examples, invalid 13 examples, total effective rate 95.7%.
(6) model case:
Zhang, female, 67 years old, people from Jinan.Within 2009, there is hypomnesis, recent amnesia is given prominence to, do not treat at that time, within 2010, develop into patient to analyze event, think deeply, judge, be difficult to process complicated problem, start to take medicine of the present invention thereupon, after 1 month, symptom alleviates, continue to take transference cure after two months, take again drug withdrawal after 2 months, do not recur so far.
Korea Spro so-and-so, man, 62 years old, Shandong middle school retired professor, can not independently carry out doing shopping, economic affairs etc., social difficulty, to the directed difficulty in residing geographical position, starts to take treatment by Chinese herbs of the present invention for 2010, transference cure after 1 month, drug withdrawal after continuing to take medicine 3 months, does not recur so far.
Lee so-and-so, female, 74 years old, people from Jinan.Independently can not carry out outdoor activity, wearing the clothes, Personal hygiene and keep wanting help in personal appearance, take Chinese medicine of the present invention after 3 months symptom greatly alleviate, drug withdrawal after continuing to take medicine 4 months, does not recur so far.
Wang, man, 68 years old now, Yantai retired employees of enterprise.Usually irritable uneasy, walk about and do not stop, urinary incontinence, within 2011, start to take Chinese medicine of the present invention, after 1 month, symptom alleviates, and transference cure after half a year of continuing to take medicine, drug withdrawal, does not recur so far.
Claims (2)
1. treat a Chinese medicine for senile dementia, it is characterized in that: be made up of the crude drug of following weight:
Olibanum 5-15g, Herba Asari 1-3g, Fructus Toosendan 7-15g, Radix Angelicae Dahuricae 3-12g, Radix Achyranthis Bidentatae 5-15g, Scolopendra 3-5g, Scorpio 5-10g, hippocampus 3-10g, Radix Puerariae 15-25g, Cortex Magnoliae Officinalis 3-10g, Poria 10-15g, succinum 2-5g, Caulis Polygoni Multiflori 2-4g, Folium Mori 5-10g, Ramulus Uncariae Cum Uncis 6-10g, Borneolum Syntheticum 0.5g, Styrax 0.3-1g, Cordyceps 3-9g, Folium Nelumbinis 3-6g, Folium ilicis serratae 10-15g, Herba Ophioglossi 10-15g, Radix onosmatis 10-15g.
2. the preparation method of the Chinese medicine for the treatment of senile dementia according to claim 1, is characterized in that: comprise the following steps: by crude drug soak by water, take.
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