CN104056025A

CN104056025A - Traditional Chinese medicine for treating angina pectoris

Info

Publication number: CN104056025A
Application number: CN201410294321.7A
Authority: CN
Inventors: 孙春林; 姜元芳
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-04-03
Filing date: 2014-06-17
Publication date: 2014-09-24

Abstract

The invention relates to the field of medicinal formulae, and particularly relates to a traditional Chinese medicine for treating angina pectoris. The traditional Chinese medicine is characterized by being prepared from the following raw medicinal materials in parts by weight: 25-35 parts of astragalus membranaceus, 10-20 parts of lonicera japonica, 10-20 parts of paniculate swallowwort root, 15-25 parts of radix ampelopsis, 3-9 parts of liquorice, 8-12 parts of szechwan Chinaberry fruit, 4-8 parts of radix angelicae pubescentis, 6-10 parts of allium macrostemon, 6-10 parts of cassia twig, 4-8 parts of cowherb seed, 4-8 parts of dried tangerine peel, 10-14 parts of hypericum sampsonii hance, 6-10 parts of glossy privet fruit and 10-14 parts of large-leaved gentian, wherein the raw medicinal materials are mixed and soaked in water, and are decocted and filtered to obtain filtrate. The traditional Chinese medicine has the beneficial effects of high curative effect, small toxic and side effect and low cost when being used for treating angina pectoris, and plays effects from the etiology and pathogenesis to achieve the function of treating and controlling angor pectoris.

Description

The Chinese medicine for the treatment of angina pectoris

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine for the treatment of angina pectoris.

Background technology

As everyone knows, angina pectoris is a class common clinical, frequently-occurring disease, is serious harm human health, affects one of disease of human life quality.In the last few years in China along with the raising of people's living standard, the change of life style, its incidence rate is growing trend, therefore strengthens the treatment of primary disease to seem particularly important.Modern medicine thinks that the pathogenesis of angina pectoris is because coronary atherosclerosis causes coronary stricture, cause coronary artery blood supply and cardiac muscle to need to conflict between blood, coronary artery blood flow can not meet the needs of myocardial metabolism and cause what cardiac muscle hypoxic-ischemic sharply, temporary transient caused.Primary disease is worked as and is belonged to motherland's medical science " thoracic obstruction ", " pained ", " chest pain ", " cardiopalmus " category by its Symptoms.Chinese medicine is used for the treatment of the advantage that angina pectoris has shown it day by day in recent years.

Summary of the invention

Object of the present invention is exactly in order to overcome above-mentioned existing technical deficiency, a kind of Chinese medicine for the treatment of angina pectoris is provided, and treatment Angina is high, toxic and side effects is little, and cost is low, set about from etiology and pathogenesis, control anginal function thereby reach treatment.

The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine for the treatment of angina pectoris, it is characterized in that being made by the crude drug of following weight portion, the Radix Astragali 25～35, Flos Lonicerae 10～20, Radix Cynanchi Paniculati 10～20, Radix Ampelopsis 15～25, Radix Glycyrrhizae 3～9, Fructus Toosendan 8～12, Radix Angelicae Pubescentis 4～8, Bulbus Allii Macrostemonis 6～10, Ramulus Cinnamomi 6～10, Semen Vaccariae 4～8, Pericarpium Citri Reticulatae 4～8, Herba Hyperici Sampsonii 10～14, Fructus Ligustri Lucidi 6～10, Radix Gentianae Macrophyllae 10～14, after being mixed, above-mentioned raw materials medicine is soaked in water, the filtrate of removing slag to obtain after decocting.

The invention has the beneficial effects as follows, treatment Angina is high, toxic and side effects is little, and cost is low, sets about from etiology and pathogenesis, controls anginal function thereby reach treatment.

Detailed description of the invention

Below in conjunction with embodiment, the invention will be further described:

Embodiment 1:

It is that crude drug is prepared from that the present embodiment adopts the Radix Astragali, Flos Lonicerae, Radix Cynanchi Paniculati, Radix Ampelopsis, Radix Glycyrrhizae, Fructus Toosendan, Radix Angelicae Pubescentis, Bulbus Allii Macrostemonis, Ramulus Cinnamomi, Semen Vaccariae, Pericarpium Citri Reticulatae, Herba Hyperici Sampsonii, Fructus Ligustri Lucidi, Radix Gentianae Macrophyllae.Its crude drug composition (weight portion) every clothes are the Radix Astragali 30, Flos Lonicerae 15, Radix Cynanchi Paniculati 15, Radix Ampelopsis 20, Radix Glycyrrhizae 6, Fructus Toosendan 10, Radix Angelicae Pubescentis 6, Bulbus Allii Macrostemonis 8, Ramulus Cinnamomi 8, Semen Vaccariae 6, Pericarpium Citri Reticulatae 6, Herba Hyperici Sampsonii 12, Fructus Ligustri Lucidi 8, Radix Gentianae Macrophyllae 12.Get above-mentioned 14 kinds of crude drug, gross mass is 250g, at room temperature 14 kinds of Chinese herbal medicine are added water to 900-1000ml, soak 4 hours, then boil with high heat slow fire and decoct to about 100-120 minute, the filtrate 200ml left and right of removing slag to obtain, the medicinal residues 300-400ml that adds water again, decoct 30-40 minute, the filtrate 100ml left and right of removing slag to obtain, decocts medicine soup 300ml left and right for twice altogether.Every day, potion was oral at twice, and each (medicine) being taken before meal 150ml left and right, seven days courses for the treatment of, takes to clinical symptom remission, generally uses eight courses for the treatment of.

Cost of material of the present invention is low, and treatment angina pectoris is effective, and safety, toxic and side effects are little.Angina pectoris belongs to the category of the traditional Chinese medical science " obstruction of qi in the chest and cardialgia ".Its patient mostly is middle-aged and elderly people.In " Plain Questions numbness opinion ", just there is the discussion of " obstruction of heart-QI pain person also has the dead blood of pertinacious phlegm ", point out that it is one of main pathogenesis of obstruction of qi in the chest and cardialgia that phlegm-turbidity and blood stasis blood is handed over resistance.The turbid same blood stasis of expectorant is usually what to hold concurrently mutually as disease, and the two is with coming from not reforming of Tianjin blood, i.e. " phlegm and blood stasis being derived from the same source ", " the expectorant stasis of blood is correlated with ".From the relation of expectorant and the stasis of blood, the stasis of blood can be given birth to expectorant, and expectorant can be made the stasis of blood; With the passing of time expectorant stagnant, must the hyperamization stasis of blood; Blood-stasis internal-depression, must give birth to expectorant for a long time, thereby forms cause and effect circulation.After the expectorant stasis of blood forms, mutually cementing, attack note with gas, numbness resistance heart arteries and veins, breast sun is not opened up, and there is chest pain, uncomfortable in chest, BHS in Gu Er.In addition, in the generation of obstruction of qi in the chest and cardialgia and pyretic toxicity, accumulate, impatency heart arteries and veins also has close relationship.In side, Radix Astragali strongly invigorating primordial QI, agitates blood operation, again can poison holding, and be monarch drug in side; Bulbus Allii Macrostemonis enters lung, the heart, stomach, large intestine channel.There is warming middle-JIAO stomach invigorating, activating YANG and eliminating stagnation, the chest stuffiness relieving of regulating the flow of vital energy, the effect of dyspepsia and intestinal stasis relieving; Fructus Ligustri Lucidi tonifying liver kidney yin, crow must improving eyesight.For the poor vision of the hepatic and renal YIN deficiency, visual deterioration, early whitening of beard and hair, soreness of waist tinnitus and fever due to yin deficiency etc., two tastes are 5 principal drug assistance benefiting QI for activating blood circulation mutually, and detoxicating and resolving stagnation of pathogens, is ministerial drug in side; Help with Flos Lonicerae heat-clearing and toxic substances removing Radix Angelicae Pubescentis dispelling wind and removing obstruction in the collateral, numbness relieving and pain relieving; Radix Glycyrrhizae and battalion's relieving spasm to stop pain, the pungent temperature of Radix Cynanchi Paniculati, return liver stomach warp, effect: the removing dampness of dispeling the wind, antalgesic-antipruritic, cure mainly: rheumatic arthralgia, stomachache distension, toothache lumbago, urticaria, eczema, traumatic injury, and have antibacterial action; Radix Ampelopsis heat clearing away, removing toxic substances, eliminating stagnation, granulation promoting, pain relieving, controls carbuncle, furuncle, scrofula, scalds pyrexial malaria, infantile convulsion, dysentery, hemorrhoidal hamorrhage, anal fistula; Ramulus Cinnamomi analgesia, calm cooling, antipyretic, control chronic hepatitis B, cervical spondylosis.There is expelling cold and relieving exterior syndrome, warming the meridian and promoting blood circulation, effect of activating YANG and prormoting functioning of QI; Semen Vaccariae bitter in the mouth, property is flat.Return liver, stomach warp.There is promoting blood circulation to restore menstrual flow, stimulating milk secretion eliminating carbuncle, effect of inducing diuresis for treating stranguria syndrome.For blood stasis amenorrhea, dysmenorrhea, difficult labour, lack of lactation after delivery, acute mastitis swells and ache, pyretic stranguria, stranguria with blood, stranguria caused by urinary stone; Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, in tune, dampness, reduces phlegm.Cure mainly: the distension and fullness in the abdomen of stagnation of QI in spleen and stomach or pain, dyspepsia.Abdominal distention uncomfortable in chest, indigestion and loss of appetite loose stool in turbid damp resistance.Phlegm-damp is stopped up the cough and asthma of lung; Herba Hyperici Sampsonii is for cooling blood for hemostasis, heat-clearing and toxic substances removing, promoting blood flow to regulate menstruation, passive wind and removing obstruction in channels.Cure mainly haematemesis, spitting of blood, epistaxis, stranguria with blood, menoxenia, dysmenorrhea, leucorrhea, traumatic injury, rheumatic arthralgia, lumbago and skelalgia; Radix Gentianae Macrophyllae energy wind-damp dispelling, reducing the asthenic fever, pain relieving, cure mainly rheumatic arthritis, low grade fever, infantile malnutrition heating; Fructus Toosendan removes damp and hot, clearing away liver-fire, pain relieving, parasite killing.Control epigastric pain with cold limbs due to adverseness of heat, hypochondriac pain, colic, abdominal pain due to worm stagnation, for making medicine in side, 14 taste Chinese medicines complement each other, and reach benefiting QI for activating blood circulation altogether, heat-clearing and toxic substances removing, blood circulation promoting competent silt effect, thus reach the effect for the treatment of conditioning angina pectoris.

The each raw material of the present invention also can be realized by this routine embodiment mixing of the listed weight of according to the form below.Its processing technique is identical with embodiment 1.(unit: weight portion)

For further investigating clinical efficacy and the safety of medicine of the present invention, select 200 routine cardiovascular and cerebrovascular disease cases to carry out clinical observation to the curative effect of medicine of the present invention.

200 routine MethodsThe cases enrolled all meet the diagnostic criteria of cardiovascular and cerebrovascular disease, make a definite diagnosis through CT, nuclear magnetic resonance, NMR, rheoencephalogram, electrocardiogram and various laboratory examination.Coronary atherosclerotic heart disease (coronary heart disease) 70 examples, myocardial infarction 50 examples, angina pectoris 80 examples.Male's 118 examples, women's 82 examples.The oldest 70 years old, minimum 39 years old.39～48 years old 42 examples, 49～59 years old 59 example, 60～70 years old 99 example.

Above case all gives the decoction of the embodiment of the present invention 1, and every day, potion was oral at twice, and each (medicine) being taken before meal 150ml left and right, seven days courses for the treatment of, takes eight courses for the treatment of.

Curative effect determinate standard: according to country " clinical disease diagnosis is according to curing improvement standard ".

Healing: after treating 3～8 courses for the treatment of, the positive sign of symptom and objective determination disappears, and has recovered normal work and viability, the recurrence of the more than 3 years nothing of Continuous Observation.

Yu turns: after treating 3～8 courses for the treatment of, the positive Signs of symptom and objective determination and cardinal symptom disappear, and have recovered certain work and self care ability, the recurrence of the more than 2 years nothing of Continuous Observation.

Invalid: through treat 8 the course for the treatment of symptom and sign be not improved.

Observe therapeutic effect in table 1 according to criterion of therapeutical effect.

The routine curative effect statistics of table 1 medicine composite for curing cardiovascular pathological changes 200 of the present invention

By 200 routine cardiovascular and cerebrovascular disease patient clinical application medicine of the present invention is treated, and long term follow-up checking efficacy result, cure rate 84.0% obtained, the significant curative effect of total effective rate 96.0%.Wherein patient with angina pectoris was obtained to cure rate 90.0% especially, the significant curative effect of total effective rate 96.7%.

Claims

1. treat the Chinese medicine of angina pectoris for one kind, it is characterized in that: the crude drug by following weight portion is made, the Radix Astragali 25～35, Flos Lonicerae 10～20, Radix Cynanchi Paniculati 10～20, Radix Ampelopsis 15～25, Radix Glycyrrhizae 3～9, Fructus Toosendan 8～12, Radix Angelicae Pubescentis 4～8, Bulbus Allii Macrostemonis 6～10, Ramulus Cinnamomi 6～10, Semen Vaccariae 4～8, Pericarpium Citri Reticulatae 4～8, Herba Hyperici Sampsonii 10～14, Fructus Ligustri Lucidi 6～10, Radix Gentianae Macrophyllae 10～14, after being mixed, above-mentioned raw materials medicine is soaked in water, the filtrate of removing slag to obtain after decocting.