CN104045553B - A kind of method of extracting ACA from Lobed Actinostemma Herb - Google Patents
A kind of method of extracting ACA from Lobed Actinostemma Herb Download PDFInfo
- Publication number
- CN104045553B CN104045553B CN201410297953.9A CN201410297953A CN104045553B CN 104045553 B CN104045553 B CN 104045553B CN 201410297953 A CN201410297953 A CN 201410297953A CN 104045553 B CN104045553 B CN 104045553B
- Authority
- CN
- China
- Prior art keywords
- aca
- ethanol
- herb
- eluent
- lobed actinostemma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 241000481592 Actinostemma Species 0.000 title claims abstract description 23
- 238000000034 method Methods 0.000 title claims abstract description 16
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 56
- 239000003480 eluent Substances 0.000 claims abstract description 19
- 230000006837 decompression Effects 0.000 claims abstract description 18
- 238000004064 recycling Methods 0.000 claims abstract description 12
- 239000011347 resin Substances 0.000 claims abstract description 10
- 229920005989 resin Polymers 0.000 claims abstract description 10
- 238000000605 extraction Methods 0.000 claims abstract description 8
- 238000010438 heat treatment Methods 0.000 claims abstract description 8
- 238000010992 reflux Methods 0.000 claims abstract description 8
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims abstract description 7
- 239000002904 solvent Substances 0.000 claims abstract description 7
- 238000010521 absorption reaction Methods 0.000 claims abstract description 6
- 238000010828 elution Methods 0.000 claims abstract description 6
- 239000011148 porous material Substances 0.000 claims abstract description 6
- 238000011084 recovery Methods 0.000 claims abstract description 6
- 238000010898 silica gel chromatography Methods 0.000 claims abstract description 6
- 235000012054 meals Nutrition 0.000 claims description 7
- 239000000047 product Substances 0.000 abstract description 3
- 239000012467 final product Substances 0.000 abstract description 2
- 150000001875 compounds Chemical class 0.000 description 5
- -1 anti-inflammatory Substances 0.000 description 3
- 230000000259 anti-tumor effect Effects 0.000 description 3
- 238000004128 high performance liquid chromatography Methods 0.000 description 3
- 238000001819 mass spectrum Methods 0.000 description 3
- 230000003595 spectral effect Effects 0.000 description 3
- 238000001228 spectrum Methods 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- NKRBAUXTIWONOV-UHFFFAOYSA-N 1'-Acetoxyeugenol acetate Natural products COC1=CC(C(OC(C)=O)C=C)=CC=C1OC(C)=O NKRBAUXTIWONOV-UHFFFAOYSA-N 0.000 description 1
- JAMQIUWGGBSIKZ-ZDUSSCGKSA-N 1'-acetoxychavicol acetate Chemical compound CC(=O)O[C@@H](C=C)C1=CC=C(OC(C)=O)C=C1 JAMQIUWGGBSIKZ-ZDUSSCGKSA-N 0.000 description 1
- 238000001644 13C nuclear magnetic resonance spectroscopy Methods 0.000 description 1
- 238000005160 1H NMR spectroscopy Methods 0.000 description 1
- 206010003445 Ascites Diseases 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 208000015817 Infant Nutrition disease Diseases 0.000 description 1
- 241001520921 Leersia virginica Species 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 208000004078 Snake Bites Diseases 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000002785 anti-thrombosis Effects 0.000 description 1
- 230000000767 anti-ulcer Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 244000000053 intestinal parasite Species 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- JAMQIUWGGBSIKZ-UHFFFAOYSA-N rac-galangal acetate Natural products CC(=O)OC(C=C)C1=CC=C(OC(C)=O)C=C1 JAMQIUWGGBSIKZ-UHFFFAOYSA-N 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 231100000611 venom Toxicity 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410297953.9A CN104045553B (en) | 2014-06-30 | 2014-06-30 | A kind of method of extracting ACA from Lobed Actinostemma Herb |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410297953.9A CN104045553B (en) | 2014-06-30 | 2014-06-30 | A kind of method of extracting ACA from Lobed Actinostemma Herb |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104045553A CN104045553A (en) | 2014-09-17 |
CN104045553B true CN104045553B (en) | 2016-05-11 |
Family
ID=51498998
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201410297953.9A Expired - Fee Related CN104045553B (en) | 2014-06-30 | 2014-06-30 | A kind of method of extracting ACA from Lobed Actinostemma Herb |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104045553B (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007088408A1 (en) * | 2006-02-03 | 2007-08-09 | Council Of Scientific And Industrial Research | A method of curing antibiotic resistant plasmids |
CN101020638A (en) * | 2007-03-18 | 2007-08-22 | 南昌弘益科技有限公司 | 1'-acetoxy chavicol acetic ester |
CN102643196A (en) * | 2012-04-24 | 2012-08-22 | 南京泽朗医药科技有限公司 | Method for preparing 1'-acetoxy chavicol acetate |
CN102826997A (en) * | 2012-09-20 | 2012-12-19 | 南京泽朗农业发展有限公司 | Method for extracting 1'-acetoxychavicol acetate from fructus galangae |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6487418A (en) * | 1987-09-30 | 1989-03-31 | Nec Corp | Feeding device for printed circuit board |
JPH1087418A (en) * | 1996-09-13 | 1998-04-07 | Res Inst For Prod Dev | Acaricide |
-
2014
- 2014-06-30 CN CN201410297953.9A patent/CN104045553B/en not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007088408A1 (en) * | 2006-02-03 | 2007-08-09 | Council Of Scientific And Industrial Research | A method of curing antibiotic resistant plasmids |
CN101020638A (en) * | 2007-03-18 | 2007-08-22 | 南昌弘益科技有限公司 | 1'-acetoxy chavicol acetic ester |
CN102643196A (en) * | 2012-04-24 | 2012-08-22 | 南京泽朗医药科技有限公司 | Method for preparing 1'-acetoxy chavicol acetate |
CN102826997A (en) * | 2012-09-20 | 2012-12-19 | 南京泽朗农业发展有限公司 | Method for extracting 1'-acetoxychavicol acetate from fructus galangae |
Also Published As
Publication number | Publication date |
---|---|
CN104045553A (en) | 2014-09-17 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Huang Shuai Inventor before: Wang Feng Inventor before: Wang Lin |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20170417 Address after: 314200 Zhejiang City, Pinghu Province Economic Development Zone, the new road No. 988, building 413-2, room Patentee after: Pinghu blue ocean Biotechnology Co.,Ltd. Address before: Tianhe District Tong East Road Guangzhou city Guangdong province 510665 B-101 No. 5, room B-118 Patentee before: GUANGDONG GAOHANG INTELLECTUAL PROPERTY OPERATION Co.,Ltd. Effective date of registration: 20170417 Address after: Tianhe District Tong East Road Guangzhou city Guangdong province 510665 B-101 No. 5, room B-118 Patentee after: GUANGDONG GAOHANG INTELLECTUAL PROPERTY OPERATION Co.,Ltd. Address before: No. 2 Taishan Road, Jiangsu science and Technology Park, 215000 Canton City of Suzhou province high tech Zone 2-104 Patentee before: Suzhou Paiteng Biological Medical Technology Co.,Ltd. |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Method for extracting 1'-acetoxychavicol acetate from Actinostemma tenerum Griff Effective date of registration: 20180223 Granted publication date: 20160511 Pledgee: Zhejiang Pinghu rural commercial bank Limited by Share Ltd. science and Technology Branch Pledgor: Pinghu blue ocean Biotechnology Co.,Ltd. Registration number: 2018330000046 |
|
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160511 Termination date: 20200630 |