CN104013798A

CN104013798A - Traditional Chinese medicine composition for treating hyperthyroidism

Info

Publication number: CN104013798A
Application number: CN201410281563.2A
Authority: CN
Inventors: 潘宝军
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-06-16
Filing date: 2014-06-16
Publication date: 2014-09-03

Abstract

The invention relates to a traditional Chinese medicine composition for treating hyperthyroidism. The traditional Chinese medicine composition is prepared from 11 traditional Chinese medicine raw materials, namely kelp, dried orange peel, rhizoma coptidis from Sichuan of China, caltrop, paeonia albiflora from Hangzhou of China, liquorice, radix sophorae flavescentis, radix ophiopogonis, fructus forsythia, tuber fleeceflower stem and elecampane. After the decoction of the traditional Chinese medicine composition is taken by a patient, the traditional Chinese medicine composition goes through the liver, the lung and the kidney from the spleen and the stomach to treat both symptoms and root causes, and has the effects of removing heat from the liver and tonifying Yin, reducing phlegm and resolving masses, nourishing and suppressing Yang, and clearing heat and dissipating phlegm; consequently, the internal environment of the human body can be changed, the diseases such as thyromegaly, bulimia, weight loss, tachycardia, irascibility, intolerance of heat and hidrosis, tremor and exophthalmos caused by the hyperthyroidism are fundamentally solved, the self-regulation functions of the immune system, the endocrine system, the nervous system, the urinary system, the digestive system, the absorption system and the blood system of the human body are recovered and complications can be prevented, and finally, the hyperthyroidism can be completely cured.

Description

A kind of Chinese medicine composition for the treatment of hyperthyroidism

Technical field

The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine composition for the treatment of hyperthyroidism.

Background technology

Hyperthyroidism is called for short hyperthyroidism in medical science, because a kind of more common endocrinopathy of thyroid hormone secretion due to too much, claim again toxicity diffusivity first shape cyst or Graves sick, it is a kind of autoimmune disease, direct stimulation, wound, the stress state such as infection are the common inducements of primary disease, and Inheritance also has certain relation, by a large amount of clinical practices, relatively consensus is that the hyperthyroidism cause of disease is mainly feelings will internal injury, physical factors, diet and water and soil are inappropriate, and stagnation of QI due to depression of the liver, QI-blood circulation is not normal, phlegm-damp cohesion, stopping up knot throat is hyperthyroidism basic pathogenesis.

Clinically mainly with thyromegaly, bulimia, lose weight, the symptom such as tachycardia, emotion are easy to excitement, To Be Protected from Heat hyperhidrosis, hands are trembled, expophthalmos judges; Women is more common in hyperthyroidism, and each age group all can be fallen ill, and can be divided into three kinds of exophthalmic goiters, secondary hyperthyroidism, high function tumor.

At present, from Chinese health education center, learn, according to conservative estimation, there are 200,000,000 Patients With Various Thyroid Disorders of surpassing in China at present, yet thyroid disease awareness is very low, whole standard treatment rate less than 5%.The < < community resident thyroid disease Epidemiological study > > that Endocrine Society of Chinese Medical Association carries out shows, China's hyperthyroidism prevalence is 1.3%, hypothyroidism prevalence is 6.5%, and resident's thyroid nodule prevalence is just up to 12.8%.China mainly contains three kinds of common therapeutic modalities now: Anti-thyroid Medicine, radioiodine therapy and operative treatment.But clinical cure case is few, and complication increases.From traditional Chinese medical science angle, the cause of disease of hyperthyroidism is that liver-fire is vigorous, the hepatic and renal YIN deficiency, seven emotions are unsuccessful, disturb in depression of liver-QI, stagnated QI transforming into fire, fluid transformed into phlegm by fire, expectorant knot cervical region, phlegm-fire, the treatment of the traditional Chinese medical science is except focusing on treatment, more focus on nourishing YIN and invigorating YANG, endocrine and the autoimmune of conditioning health, therefore be one of current effective and feasible Therapeutic Method from the angle treatment hyperthyroidism of the traditional Chinese medical science.

Summary of the invention

The problem to be solved in the present invention is for above problem, and a kind of Chinese medicine composition for the treatment of hyperthyroidism is provided, and this medicine adopts theory of Chinese medical science, and hyperthyroidism is treated and taken good care of, and has good therapeutic effect.

For addressing the above problem, the technical solution adopted in the present invention is:

A Chinese medicine composition for the treatment of hyperthyroidism, is characterized in that, described Chinese medicine composition is comprised of the Chinese herb of following weight portion:

Thallus Laminariae (Thallus Eckloniae) 20-30 gram, Pericarpium Citri Reticulatae 20-30 gram, Rhizoma Coptidis 10-20 gram, Fructus Tribuli 10-20 gram, Radix Paeoniae Alba 10-20 gram, Radix Glycyrrhizae 10-20 gram, Radix Sophorae Flavescentis 10-20 gram, 10-20 gram of Radix Ophiopogonis, Fructus Forsythiae 5-10 gram, Caulis Polygoni Multiflori 5-10 gram, Radix Aucklandiae 5-10 gram.

As a kind of prioritization scheme:

Described medicine is comprised of the Chinese medicine of following weight portion:

30 grams of Thallus Laminariae (Thallus Eckloniae)s, 25 grams of Pericarpium Citri Reticulataes, 20 grams of Rhizoma Coptidis, 15 grams of Fructus Tribulis, 15 grams of Radix Paeoniae Alba, 20 grams, Radix Glycyrrhizae, 10 grams of Radix Sophorae Flavescentiss, 15 grams of Radix Ophiopogonis, 5 grams of Fructus Forsythiaes, 10 grams of Caulis Polygoni Multiflori, 5 grams of the Radix Aucklandiae.

As a kind of prioritization scheme:

25 grams of Thallus Laminariae (Thallus Eckloniae)s, 30 grams of Pericarpium Citri Reticulataes, 15 grams of Rhizoma Coptidis, 10 grams of Fructus Tribulis, 20 grams of Radix Paeoniae Alba, 10 grams, Radix Glycyrrhizae, 15 grams of Radix Sophorae Flavescentiss, 20 grams of Radix Ophiopogonis, 5 grams of Fructus Forsythiaes, 5 grams of Caulis Polygoni Multiflori, 5 grams of the Radix Aucklandiae.

As a kind of prioritization scheme:

20 grams of Thallus Laminariae (Thallus Eckloniae)s, 30 grams of Pericarpium Citri Reticulataes, 10 grams of Rhizoma Coptidis, 20 grams of Fructus Tribulis, 15 grams of Radix Paeoniae Alba, 15 grams, Radix Glycyrrhizae, 15 grams of Radix Sophorae Flavescentiss, 10 grams of Radix Ophiopogonis, 10 grams of Fructus Forsythiaes, 5 grams of Caulis Polygoni Multiflori, 10 grams of the Radix Aucklandiae.

Wherein:

Thallus Laminariae (Thallus Eckloniae) salty in the mouth, cold in nature, nontoxic, it is a kind of algae, return liver, stomach, kidney channel, contain algin element (algin), mannitol (mannitol), galactan (galactan), laminine (laminine), Thallus Laminariae (Thallus Eckloniae) polysaccharide (laminarin), glutamic acid, aspartic acid, proline, vitamin B1, vitamin C, Citrin and iodine, potassium etc., it is the vegetable that a kind of nutritive value is very high, there is the hyperthyroid metabolism rate of inhibition, antioxidation, anti-cancer, blood pressure lowering, blood fat reducing, blood sugar lowering, anticoagulant, the effects such as radioprotective, cure mainly hard masses softening and resolving, expectorant, diuretic.

Pericarpium Citri Reticulatae, bitter in the mouth, warm in nature, enter spleen, stomach, kidney channel, the effect such as have regulating qi-flowing for strengthening spleen, dampness, reduce phlegm, cures mainly the distension and fullness in the abdomen of stagnation of QI in spleen and stomach or pain, dyspepsia, abdominal distention uncomfortable in chest, indigestion and loss of appetite loose stool in turbid damp resistance, phlegm-damp is stopped up the symptoms such as cough and asthma of lung.

Rhizoma Coptidis is Rhizoma Coptidis, has the effects such as heat clearing away, dampness, pathogenic fire purging, removing toxic substances, the clear part of the body cavity above the diaphragm housing the heart and lungs are burning hot, clearing stomach, stomach preventing or arresting vomiting, soothing liver-QI; The pharmacological action of Rhizoma Coptidis has antibacterial action, antifungic action, antivirus action, anti-ameba effect, antiinflammatory, diarrhea effect, on Cardiovascular, refrigeration function, hypoglycemic activity, effect for reducing blood fat, antioxidation, on the impact of blood system, antiulcer action.

Fructus Tribuli bitter in the mouth, cold in nature, poisonous, return Liver Channel, be difficult for many clothes, there is suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, the effect such as antipruritic.

Radix Paeoniae Alba is exactly the Radix Paeoniae Alba of often saying, and best in quality because of the Radix Paeoniae Alba that produce in Hangzhou, so title Radix Paeoniae Alba, function is easing the affected liver, pain relieving, nourish blood, regulating menstruation, yin fluid astringing, hidroschesis etc.

Radix Glycyrrhizae is a kind of tonification Chinese herbal medicine, to the good Chinese medicine of human body, enters spleen, stomach, Liver Channel, has the effects such as invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, clear throat, relieving spasm to stop pain, cures mainly the diseases such as asthma and cough, ulcer sores, laryngopharynx swelling and pain; Radix Glycyrrhizae or enoxolone have the effect of desoxycortone class, and chronic adrenocortical hypofunction is had to good efficacy, can protect throat and the tunica mucosa tracheae of inflammation, to antitussive, eliminating the phlegm also has good effect.

Radix Sophorae Flavescentis, bitter in the mouth, cold in nature, enter liver, kidney, large intestine, small intestine meridian, there is antitumor, regulate cardiovascular system, promote quantity of leucocyte, relieving asthma eliminate the phlegm, stabilize, the effect such as antiallergic, immunosuppressant.

There is yin nourishing Radix Ophiopogonis, promote the production of body fluid, lung moistening, clear away heart-fire, the effect of heat clearing away, cough-relieving.

The water decoction of Fructus Forsythiae is mainly containing compounds such as phenethyl alcohol glycosides, lignan and glycoside thereof, pentacyclic triterpene Lou, volatile oils, and pharmacological research thinks that it has antibacterial, antiinflammatory, antipyretic, tell in town, diuresis heart tonifying, anti-liver damage, analgesia, suppress the effects such as phosphodiesterase, antiviral, blood pressure lowering, inhibition elastin laminin enzyme activity, antiendotoxin; Tool heat clearing away, antiinflammatory, the effects such as knot, evacuation of pus, hypertension, dysentery, throat pain of detoxifying, disappear.

Caulis Polygoni Multiflori, property is flat nontoxic, sweet and slightly bitter taste, enters the heart, Liver Channel, have calm the nerves, nourish blood, dispel the wind, the effect of dredging collateral, cure mainly the diseases such as deficiency of YIN insufficiency of blood, restlessness of asrhenia type and insomnia, rheumatic arthralgia, itchy skin eruption, impairment caused by overstrain, hyperhidrosis, blood deficiency general pain.

The Radix Aucklandiae enters the heart, lung, liver, spleen, stomach, bladder the six channels, and main effect is circulation of qi promoting, pain relieving, spleen invigorating, help digestion etc.

From traditional Chinese medical science angle, hyperthyroidism is from the beginning of how real, and how empty prolonged illness is; Drinking and eating irregularly or inappropriate because of water and soil, affects transformation and transportation of the spleen and stomach, dysfunction of the spleen in transportation, and accumulatively wet raise phlegm, multiple because of depression of liver-QI, QI-blood circulation is not smooth, and expectorant and depressed is stopped up and in throat, is formed wart and swell; Long-term angry strongly fragrant angry, feelings will is not relaxed, and causes stagnation of QI due to depression of the liver, and body fluid is not transported for it, is condensed into expectorant, and mental disorder is handed over resistance and gradually become hyperthyroidism.If the stagnation of QI is with the passing of time, or patient's element body deficiency of YIN, be easy to the gesture that fire-transformation forms overabundant liver-fire, if expectorant knot is with the passing of time, QI-blood circulation is not normal, causes qi depression to blood stasis, can make wart swollen hard; Overabundant liver-fire, burns bright Liver Channel, consumption impairment of YIN blood, and the feature such as women's warp, band, tire, product, breast also easily causes deficiency of YIN-blood, the body of one-tenth hyperactivity of fire caused by deficiency of YIN in addition; Because of " hyperactive fire wasting QI ", hyperactivity of fire is with the passing of time felt frustrated again, causes the card of deficiency of both QI and YIN; Above etiology and pathogenesis connects each other often.

Chinese medicine composition of the present invention, really based on above-mentioned theory, by drawing after clinical prescription compatibility for several times, its manufacture method is simple, can be made into as required tablet, pill, the dosage form such as powder or oral liquid, after taking, medicine enters spleen, stomach, through liver, lung, kidney, treating both the principal and secondary aspects of a disease, there is liver heat removing yin nourishing, dissipating phlegm and resolving masses, nourishing YIN for suppressing the hyperactive YANG, the effect of removing heat-phlegm, change the interior environment of human body, fundamentally solve the thyromegaly causing because of hyperthyroidism, bulimia, lose weight, tachycardia, emotion is easy to excitement, hyperhidrosis that To Be Protected from Heat, hands is trembled, the diseases such as expophthalmos, make the immune system of self, hormonal system, nervous system, urinary system, digestive system, absorption system and blood system recover the function of self regulation the generation of complication prevention, finally realize the thorough treatment to hyperthyroidism.

Instructions of taking: every day potion, every day three times, bfore meals, within ten days, be a course for the treatment of.

The present invention is according to the pharmacology of above-mentioned Chinese medicine, and clinical trial for several times, to green grass or young crops, in, old all ages and classes section light, in, severe hyperthyroid patient, and graves (Graves is sick), multinodular goiter companion first, autonomous hyperfunctional thyroid nodule, neonate hyperthyroidism, iodine hyperthyroidism, pituitary tumor causes hyperthyroidism, non-pituitary tumor causes hyperthyroidism, chorionic epithelioma companion hyperthyroidism, grape tire companion hyperthyroidism, lung cancer accompanied hyperthyroidism, Digestive (stomach, colon, pancreas) companion such as cancer hyperthyroidism, struma ovarii companion first, subacute thyroiditis, chronic lymphocytic thyroiditis, the patient that radiation thyroiditis etc. are tens types all has obvious therapeutic effect.

In order further to investigate clinical efficacy and the safety of medicine of the present invention, we selected 200 examples light, in, severe patients with hyperthyroidism carries out clinical trial with the therapeutic effect of medicine of the present invention.

200 examples are light, in, severe patient is divided into two groups at random, every group of 100 routine patients, in matched group, male's 31 examples, women's 69 examples: following 20 examples of 40 years old age, 41～60 years old 51 example, 60 years old above 29 example; The course of disease 3 months to 3 years; In treatment group, male's 29 examples, women's 71 examples: following 18 examples of 40 years old age, 41～60 years old 53 example, 60 years old above 29 example; The course of disease 4 months to 4 years.

Two groups of cases are Epidemiological Analysis by statistics at aspects such as sex, age, the courses of disease, has comparability.All cases are all diagnosed with reference to the diagnostic criteria of hyperthyroidism in < < internal medicine > >.

Matched group adopts common Therapeutic Method at present.Generally according to symptom, take Western medicine thiamazole sheet, every day three times; The water decoction of the oral medicine of the present invention for the treatment of group, potion on the one, potion divides to be taken for three times.

Criterion of therapeutical effect:

Cure---clinical symptom disappearance, goiter, expophthalmos and relevant sign are recovered normally substantially, and it is normal that thyroid function is recovered.

Effective---clinical symptoms disappears substantially, and goiter, expophthalmos and relevant sign obviously alleviate, and thyroid function inspection approaches normal.

Effectively---clinical symptoms is clearly better, and goiter, expophthalmos and relevant sign alleviate to some extent, and thyroid function inspection takes a turn for the better to some extent.

Invalid---clinical symptoms and sign are without improvement, and thyroid function checks without changing.

Concrete test data as shown in Table 1.

Table one

Group	Number of cases	Cure n (%)	Effective n (%)	Effective n (%)	Invalid n (%)	Total effective rate n (%)
							Matched group	100	60(40.0)	70(70.0)	85(85.0)	15(15.0)	85(85.0)
Treatment group	100	70(70.0)	85(85.0)	99(99.0)	1(1.00)	99(99.0)

By the data in above-mentioned table one, contrast, can find out that the cure rate of medicine of the present invention is high, therapeutic effect is remarkable, compare with taking Western medicine, not only total effective rate is high, and treating both the principal and secondary aspects of a disease, can fundamentally cure hyperthyroidism, and good stability is difficult for recurrence.

The specific embodiment

Embodiment 1: a kind of Chinese medicine composition for the treatment of hyperthyroidism, described medicine is comprised of 5 grams of 30 grams of Thallus Laminariae (Thallus Eckloniae)s, 25 grams of Pericarpium Citri Reticulataes, 20 grams of Rhizoma Coptidis, 15 grams of Fructus Tribulis, 15 grams of Radix Paeoniae Alba, 20 grams, Radix Glycyrrhizae, 10 grams of Radix Sophorae Flavescentiss, 15 grams of Radix Ophiopogonis, 5 grams of Fructus Forsythiaes, 10 grams of Caulis Polygoni Multiflori, the Radix Aucklandiae.

After above-mentioned Chinese herb is mixed, decoct with water half an hour, elimination medicinal residues, just oral water decoction, every day potion, every natural gift are taken for three times, bfore meals, it within ten days, is a course for the treatment of, just can fully recover three to four courses for the treatment of, certainly can to dose, carry out suitable interpolation or minimizing according to symptom or age, and follow the doctor's advice, during taking, avoid pungently, avoid and flare up.

Embodiment 2: a kind of Chinese medicine composition for the treatment of hyperthyroidism, described medicine is comprised of 5 grams of 25 grams of Thallus Laminariae (Thallus Eckloniae)s, 30 grams of Pericarpium Citri Reticulataes, 15 grams of Rhizoma Coptidis, 10 grams of Fructus Tribulis, 20 grams of Radix Paeoniae Alba, 10 grams, Radix Glycyrrhizae, 15 grams of Radix Sophorae Flavescentiss, 20 grams of Radix Ophiopogonis, 5 grams of Fructus Forsythiaes, 5 grams of Caulis Polygoni Multiflori, the Radix Aucklandiae.

Embodiment 3: a kind of Chinese medicine composition for the treatment of hyperthyroidism, described medicine is comprised of 10 grams of 20 grams of Thallus Laminariae (Thallus Eckloniae)s, 30 grams of Pericarpium Citri Reticulataes, 10 grams of Rhizoma Coptidis, 20 grams of Fructus Tribulis, 15 grams of Radix Paeoniae Alba, 15 grams, Radix Glycyrrhizae, 15 grams of Radix Sophorae Flavescentiss, 10 grams of Radix Ophiopogonis, 10 grams of Fructus Forsythiaes, 5 grams of Caulis Polygoni Multiflori, the Radix Aucklandiae.

Part cure disease for example under:

Wu XX, female, 30 years old, patient originally have greedy sleep, spirit is poor, the symptom of fatiguability, hypomnesis, be diagnosed as on inspection multiple thyroid nodule, actively coordinate medical treatment, can after triennium in the state of an illness always bad during fashion, symptom does not have to take a turn for the better substantially, body weight has also increased by 16 jin than originally, after taking a course for the treatment of of the present invention, clinical symptoms is clearly better, the relevant sign of thyroid alleviates to some extent, thyroid function inspection takes a turn for the better to some extent, continues to take after two courses for the treatment of, and symptom disappears substantially, after taking again a course for the treatment of, fully recover, without recurrence.

Yellow XX, female, 40 years old, the malaise symptoms such as patient often has that nervous asthma, puffiness of face, sight stagnate, loose swollen, the irritated irritability of eyelid, amenorrhea, insomnia, be diagnosed as on inspection hyperthyroidism, take a course for the treatment of of the present invention after clinical symptoms substantially disappear, sign obviously alleviates, thyroid function inspection approaches normal, fully recovers after continuing to take a course for the treatment of.

King XX, man, 52 years old, patient's hyperthyroidism to show as neck thick, eyes protrude, through the treatment of half a year, not only the state of an illness does not alleviate, and it is hoarse that sound becomes, and appetite increases, have and do not want to adopt operative therapy: take after two courses for the treatment of of the present invention, clinical symptoms disappears substantially, and goiter, expophthalmos and relevant sign obviously alleviate, and thyroid function inspection approaches normal, after continuing to take a course for the treatment of, fully recover, without recurrence.

Claims

1. a Chinese medicine composition for the treatment of hyperthyroidism, is characterized in that, described Chinese medicine composition is comprised of the Chinese herb of following weight portion:

2. Chinese medicine composition according to claim 1, is characterized in that: described medicine is comprised of the Chinese medicine of following weight portion:

3. Chinese medicine composition according to claim 1, is characterized in that: described medicine is comprised of the Chinese medicine of following weight portion:

4. Chinese medicine composition according to claim 1, is characterized in that: described medicine is comprised of the Chinese medicine of following weight portion: