CN104012570A - Indoxacarb-chlorpyrifos suspoemulsion and preparation method thereof - Google Patents
Indoxacarb-chlorpyrifos suspoemulsion and preparation method thereof Download PDFInfo
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- CN104012570A CN104012570A CN201410298937.1A CN201410298937A CN104012570A CN 104012570 A CN104012570 A CN 104012570A CN 201410298937 A CN201410298937 A CN 201410298937A CN 104012570 A CN104012570 A CN 104012570A
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- indoxacarb
- chlopyrifos
- chlorpyrifos
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Abstract
The invention provides an indoxacarb-chlorpyrifos suspoemulsion and a preparation method thereof, belonging to the technical field of pesticide. The indoxacarb-chlorpyrifos suspoemulsion comprises the following active ingredients: indoxacarb, chlorpyrifos, a disperser, an emulsifier, a cosolvent, an antifreezer, magnesium aluminosilicate, a co-emulsifier, xanthan gum XG, and sodium carboxymethyl cellulose CMC. According to the characteristics, indoxacarb and chlorpyrifos are prepared into a mixing agent, so that the prevention range of indoxacarb and chlorpyrifos can be widened, the resistance can be overcome or postponed, and the cost of products can also be lowered.
Description
Technical field
The present invention relates to a kind of insecticide, specifically, by the suspension emulsion of indoxacarb and chlopyrifos, belong to pesticide field.
Background technology
Chlopyrifos is a kind of pesticide species of high-efficiency low-toxicity, use extensively, consumption is large, have tag, stomach toxicity and fumigation action, can prevent and treat rice leaf roller, two-spotted spider mite, rice fulgorid, pink tea rust mite, smaller green leaf hopper, mosquito, fly, wheat armyworm and cattle and sheep vermin and soil insect.But regular dosage form-missible oil of chlopyrifos, the consumption of organic solvent is large, has not only polluted environment, humans and animals is damaged, and wasted petroleum resources increasingly in short supply, and be not suitable for the development trend of current water baseization of pesticidal preparations, more can not meet the needs of Environmental security.So be badly in need of developing water baseization chlopyrifos novel form.Indoxacarb is a kind of Xin Xing oxadiazine insecticides, and its mechanism of action is by blocking-up insect nerve cell sodium-ion channel, makes nerve cell loss of function.Indoxacarb taking tag and stomach poison function as main, be there is not to cross resistance in other insecticides, and to natural enemy insect safety, can be used for integrated pest management (IPM) and resistance management (RPM).Because indoxacarb systemic action is poor and price is more expensive, limit to a certain extent his scope of application.
Summary of the invention
The object of the invention is, for the deficiencies in the prior art, a kind of indoxacarb-chlopyrifos suspension emulsion and preparation method thereof is provided, indoxacarb and chlopyrifos are made to mixture according to its characteristic, both can expand the two prevention and treatment range, overcome or the generation of delaying drug resistance, can reduce again the cost of product simultaneously.
Technical solution of the present invention is that a kind of indoxacarb-chlopyrifos suspension emulsion comprises following component:
Wherein, indoxacarb: chlopyrifos (m:m)=1:4-1:5, dispersant is selected D-425, and emulsifier is PNP10 and agriculture breast 1601 mixtures or PNP10 and agriculture breast 1602 mixtures, antifreezing agent is ethylene glycol or glycerine or propane diols, and assistant for emulsifying agent is NS500-LQ.
Preparation method: owing to being solid-state fusing point lower (42.5-43 DEG C) under chlopyrifos normal temperature, be not suitable for being directly processed into suspending agent, therefore in the time preparing indoxacarb-chlopyrifos suspension emulsion, first chlopyrifos is mixed with to aqueous emulsion, grind with aqueous emulsion finished product.Indoxacarb is placed in to chlorpyrifos aqueous emulsion disperse phase and carries out frosted 3h, add PH conditioning agent after making finished product, regulation system PH between 6-7, the indoxacarb-chlopyrifos suspension emulsion having good stability that can make.
The present invention has following beneficial effect:
1. indoxacarb Shu Yu oxadiazine class sodium channel inhibitor, its mechanism of action is mainly the sodium channel in blocking-up insect nerve cell, causes target pest imbalance, paralysis, finally dead, has and tags and stomach poison function.Enter polypide by contacting and ingesting, the behavior of insect changes rapidly, causes insect to stop rapidly ingesting.Chlopyrifos be have tag, the organophosphorus insecticides of stomach toxicity and fumigation action, its Main Function is in insect acetylcholinesterase, show the features such as insecticidal spectrum is wide, drug effect is fast, if therefore two kinds of medicaments carry out mixture with proper proportion, can have complementary advantages and the difference of mechanism of action also can delay the generation of pest resistance to insecticide.The present invention studies have shown that, indoxacarb is equipped with chlorpyrifos mixture that suitable proportion is mixed has obvious synergistic effect to diamond-back moth.
2. the present invention adopts suspending agent, and suspending agent is water baseization environmental protection formulation, in formula not with an organic solvent, easy to process, efficacy stability.
3. the present invention has determined best proportioning and the best processing technology of indoxacarb-chlopyrifos mixture, for scientific basic has been established in the exploitation of this mixture.Ratio range of the present invention can the maximum Synergistic insecticidal effect of bringing into play indoxacarb and chlopyrifos.
Embodiment
Embodiment 1.30% chlorpyrifos aqueous emulsion
(1) 30% chlorpyrifos aqueous emulsion formula
(2) compound method: by formula requirement, each component mix and blend is dissolved and makes oil phase.Under 60～90r/min stirring action, water is directly added in oil phase, stir about 30min, obtains shallow emulsion liquid, obtains chlorpyrifos aqueous emulsion product after sample analysis is qualified.
(3) stability experiment
30% chlorpyrifos aqueous emulsion, if formulation selection is improper, not only aqueous emulsion system is unstable, and active ingredient can decompose, particularly, with the increasing of pH value, decomposition rate is accelerated.Therefore in the formula development of aqueous emulsion, it is very crucial problem that stable system and active ingredient are decomposed.The present invention is by study on the stability, and this formula heat in the situation that of 54 ± 2 DEG C is store after 14d, system appearance stablity, active ingredient resolution ratio (table 1) below 5%.
Table 1.30% chlorpyrifos aqueous emulsion quality evaluation result
Embodiment 2. indoxacarbs-chlopyrifos 25% suspension emulsion
(1) formula
(2) preparation method: first chlopyrifos is mixed with to 30% aqueous emulsion according to method described in embodiment 1, indoxacarb and all the other components are placed in to chlorpyrifos aqueous emulsion disperse phase and carry out frosted 3h, after making finished product, add PH conditioning agent, regulation system PH between 6-7, the indoxacarb-chlopyrifos having good stability 25% suspension emulsion that can make.
(3) stability experiment
According to this formula, indoxacarb-chlopyrifos 25% suspension emulsion that processing obtains, carries out quality index detection, the results are shown in Table 2, and the visible every quality index of indoxacarb-chlopyrifos 25% suspension emulsion of the present invention meets relevant quality standard.
Table 2. indoxacarb-chlopyrifos 25% suspension emulsion quality evaluation result
Embodiment 3. indoxacarbs-chlopyrifos 30% suspension emulsion
(1) formula
(2) preparation method: first chlopyrifos is mixed with to 30% aqueous emulsion according to method described in embodiment 1, indoxacarb and all the other components are placed in to chlorpyrifos aqueous emulsion disperse phase and carry out frosted 3h, after making finished product, add PH conditioning agent, regulation system PH between 6-7, the indoxacarb-chlopyrifos having good stability 30% suspension emulsion that can make.
(3) stability experiment
According to this formula, indoxacarb-chlopyrifos 30% suspension emulsion that processing obtains, carries out quality index detection, the results are shown in Table 3, and the visible every quality index of indoxacarb-chlopyrifos 30% suspension emulsion of the present invention meets relevant quality standard.
Table 3. indoxacarb-chlopyrifos 30% suspension emulsion quality evaluation result
Embodiment 4. indoxacarbs-chlopyrifos 20% suspension emulsion
(1) formula
(2) preparation method: first chlopyrifos is mixed with to 30% aqueous emulsion according to method described in embodiment 1, indoxacarb and all the other components are placed in to chlorpyrifos aqueous emulsion disperse phase and carry out frosted 3h, after making finished product, add PH conditioning agent, regulation system PH between 6-7, the indoxacarb-chlopyrifos having good stability 20% suspension emulsion that can make.
Stability experiment is tied and is shown, the every quality index of indoxacarb-chlopyrifos 20% suspension emulsion of the present invention meets relevant quality standard.
Embodiment 5. indoxacarbs-chlopyrifos 35% suspension emulsion
(1) formula
(2) preparation method: first chlopyrifos is mixed with to 30% aqueous emulsion according to method described in embodiment 1, indoxacarb and all the other components are placed in to chlorpyrifos aqueous emulsion disperse phase and carry out frosted 3h, after making finished product, add PH conditioning agent, regulation system PH between 6-7, the indoxacarb-chlopyrifos having good stability 35% suspension emulsion that can make.
Stability experiment is tied and is shown, the every quality index of indoxacarb-chlopyrifos 20% suspension emulsion of the present invention meets relevant quality standard.
Test example 1. is got indoxacarb-chlopyrifos suspension emulsion of embodiment 2,3,4 and 5 diamond-back moth co-toxicity is measured.The results are shown in Table 4
Table 4. indoxacarb-chlopyrifos suspension emulsion is to diamond-back moth co-toxicity
As can be seen from Table 4, indoxacarb of the present invention is equipped with chlorpyrifos mixture that suitable proportion is mixed has obvious synergistic effect to diamond-back moth.
Claims (3)
1. indoxacarb-chlopyrifos suspension emulsion, is characterized in that, comprises following component:
Wherein, indoxacarb: chlopyrifos (m:m)=1:4-1:5; Dispersant is D-425; Emulsifier is PNP10 and agriculture breast 1601 mixtures or PNP10 and agriculture breast 1602 mixtures; Antifreezing agent is ethylene glycol or glycerine or propane diols; Assistant for emulsifying agent is NS500-LQ.
2. indoxacarb-chlopyrifos suspension emulsion as claimed in claim 1, is characterized in that, comprises following component:
3. the preparation method of indoxacarb-chlopyrifos suspension emulsion, it is characterized in that, first chlopyrifos is mixed with to 30% aqueous emulsion, then indoxacarb and all the other components are placed in to chlorpyrifos aqueous emulsion disperse phase and carry out frosted 3h, after making finished product, add PH conditioning agent, regulation system PH, between 6-7, makes the indoxacarb-chlopyrifos suspension emulsion having good stability.
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| CN201410298937.1A CN104012570A (en) | 2014-06-27 | 2014-06-27 | Indoxacarb-chlorpyrifos suspoemulsion and preparation method thereof |
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| CN201410298937.1A CN104012570A (en) | 2014-06-27 | 2014-06-27 | Indoxacarb-chlorpyrifos suspoemulsion and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106106504A (en) * | 2016-06-27 | 2016-11-16 | 江苏新农化工有限公司 | Pesticidal combination containing chlorpyrifos-methyl and preparation thereof and application |
| CN107593759A (en) * | 2017-11-01 | 2018-01-19 | 昭平县科学技术实验场 | A kind of Recompounded pesticide |
| CN107853321A (en) * | 2017-11-01 | 2018-03-30 | 昭平县科学技术实验场 | A kind of Recompounded pesticide effervescent tablet |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101116445A (en) * | 2007-09-10 | 2008-02-06 | 浙江省农业科学院 | Method for improving the effect of chemical agent for preventing and curing lepidopterous pests |
-
2014
- 2014-06-27 CN CN201410298937.1A patent/CN104012570A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101116445A (en) * | 2007-09-10 | 2008-02-06 | 浙江省农业科学院 | Method for improving the effect of chemical agent for preventing and curing lepidopterous pests |
Non-Patent Citations (1)
| Title |
|---|
| 郭武棣: "《液体制剂》", 31 January 2004 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106106504A (en) * | 2016-06-27 | 2016-11-16 | 江苏新农化工有限公司 | Pesticidal combination containing chlorpyrifos-methyl and preparation thereof and application |
| CN107593759A (en) * | 2017-11-01 | 2018-01-19 | 昭平县科学技术实验场 | A kind of Recompounded pesticide |
| CN107853321A (en) * | 2017-11-01 | 2018-03-30 | 昭平县科学技术实验场 | A kind of Recompounded pesticide effervescent tablet |
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Application publication date: 20140903 |