CN104001060A - Coating ointment for treating pharyngitis and preparation method thereof - Google Patents
Coating ointment for treating pharyngitis and preparation method thereof Download PDFInfo
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- CN104001060A CN104001060A CN201410262583.5A CN201410262583A CN104001060A CN 104001060 A CN104001060 A CN 104001060A CN 201410262583 A CN201410262583 A CN 201410262583A CN 104001060 A CN104001060 A CN 104001060A
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Abstract
The invention discloses a coating ointment for treating with pharyngitis and a preparation method of the coating ointment. The coating ointment is cream formed by mixing main medicine and adjuvant concentrate. The main medicine is obtained by mixing mint, siraitia grosvenorii flowers, papilionaceae abrus precatorius leaves, wild chrysanthemums, radix glycyrrhizae and trchosahthes kirilowii maxin and then grinding the materials into powder. The adjuvant concentrate is obtained by mixing rice root hair, wild jujube, pomelo peels, orange peels and figs, decocting the mixture in saline water and then filtering out solid matter, wherein rice root hair, wild jujube, pomelo peels, orange peels and figs are used as adjuvant, and the mass concentration of the saline water is 15%. According to the coating ointment, the appropriate medicinal materials are selected and made into medicinal powder, medicinal powder is mixed with the adjuvant concentrate into the cream, the cream is applied to the throat of a patient, the ointment directly acts on the disease position for a long time, and the rapid analgesic and detumescent effect is achieved; the coating ointment comprises orange peels, mints, radix glycyrrhizae and the like which all have the effect on decreasing internal heat and the anti-inflammation effect, and the components have the positive auxiliary function in treatment of pharyngitis.
Description
Technical field
The present invention relates to the medicine that use in disease treatment field, specifically a kind of coating cream for the treatment of pharyngitis and preparation method thereof.
Background technology
Pharyngitis is pharyngeal mucosa, and the inflammation of submucous tissue is often a part for upper respiratory tract infection.According to the length of the course of disease and the difference of pathological change character, be divided into acute pharyngitis, the large class of chronic pharyngitis two.The cardinal symptom of acute pharyngolaryngitis is that onset is anxious, from the beginning of time pharyngeal dry, scorching hot, pain then, more obvious when while swallowing saliva, pharyngalgia is often than feed, the heat that can occur together, headache, inappetence and extremities aching pain, invade and throat, can neigh and cough by accompanying sound.The cardinal symptom of chronic pharyngolaryngitis is pharyngeal discomfort, does, itches, swollen, and secretions is many and causalgia is easy to dry, has foreign body sensation, and not out, can not swallow; Above symptom especially can be speaking after slightly many, edible irritable food, increase the weight of when fatigue or Changes in weather.Existing treating pharyngitis medicine generally all adopts Western medicine for oral administration, and onset time is longer.
Summary of the invention
The slow problem of onset, the invention provides a kind of coating cream for the treatment of pharyngitis and preparation method thereof when solving existing western medicine pharyngitis for oral administration, and this drop drips swell and ache sense and the inflammation that behind the throat position of sufferer, can eliminate fast throat.
The present invention solves the problems of the technologies described above the technical scheme of employing to be: a kind of coating cream for the treatment of pharyngitis, the paste forming according to the weight ratio mix of 1:1.5-3 for principal agent and accessory drugs concentrate, wherein, principal agent is by Herba Menthae, flower of Fructus Momordicae, leaf of Caulis et Folium Abri, Flos Chrysanthemi Indici, the ratio that Radix Glycyrrhizae and Fructus Trichosanthis are 12-14:3-5:2-4:3-5:6-7:8-9 according to weight ratio is mixed rear pulverizing and is obtained, accessory drugs concentrated solution must by the rice root as accessory drugs, Ziziphi Spinosae, pomelo peel, Pericarpium Citri tangerinae and Fructus Fici are in 15% saline, after infusion, to filter out solid matter to obtain in mass concentration after mixing according to the ratio of weight ratio 1:3-4:2-3:2-4:3-5.
The medicated powder fineness that described principal agent is worn into is no more than 100 orders.
Described accessory drugs also comprises Flos Chrysanthemi Indici, and the addition of Flos Chrysanthemi Indici is 2-3 times of rice root palpus.
In described accessory drugs concentrated solution, accessory drugs and the salt water weight ratio adding are 1:7-9, and the infusion gross weight that finishes rear surplus materials be accessory drugs initial weight 2-3 doubly.
The preparation method of the coating cream of above-mentioned treatment pharyngitis, comprises the following steps:
1) preparation of principal agent medicated powder
Get Herba Menthae, flower of Fructus Momordicae, leaf of Caulis et Folium Abri, Flos Chrysanthemi Indici, Radix Glycyrrhizae and Fructus Trichosanthis according to weight ratio and wear into fineness after dry and be no more than 100 object powder, for subsequent use;
2) producing of accessory drugs concentrate
Take accessory drugs according to weight ratio, and after being mixed, put in infusion vessel, after adding wherein the saline that accessory drugs weight 7-9 mass concentration is doubly 15%, make to boil with high heat, use again slow fire infusion instead, until the weight of the interior residue of vessel becomes 2-3 times of accessory drugs initial weight, then stop heating, the liquid that after natural cooling, filtration solids wherein obtains is accessory drugs concentrate, for subsequent use;
3) mix becomes cream
In the medicated powder making to step 1), adding step 2) mix becomes paste to obtain product after the accessory drugs concentrate produced, and the weight ratio of medicated powder and accessory drugs concentrate is 1:1.5-3.
In the present invention's principal agent used, Herba Menthae has effect of dispelling wind and heat pathogens, the clear sharp head, sore-throat relieving rash, soothing the liver circulation of qi promoting, Radix Glycyrrhizae has effect of nourishing the lung to arrest cough, eliminating fire and detoxication, coordinating the actions of various ingredients in a prescription, flower of Fructus Momordicae has the effect wetting one's whistle, leaf of Caulis et Folium Abri has effect of promoting the production of body fluid to quench thirst, moistening lung and clearing heat, and Flos Chrysanthemi Indici has the medicinal efficacies such as dispelling wind, heat clearing away, removing toxic substances, detumescence, improving eyesight;
In accessory drugs used, Ziziphi Spinosae, the thing such as pomelo peel and Pericarpium Citri tangerinae all has pharynx-clearing throat-benefiting, the similar effects such as antiinflammatory pathogenic fire reducing, can not have side effects, and wherein also add have rice root must and Fructus Fici carry out infusion with medicinal ingredient wherein of extraction, and by accessory drugs infusion in saline, not only can destroy cell wall, effective ingredient in medical material is discharged as far as possible, and mix becomes while being coated on throat after cream, sodium chloride acts on can cause certain stimulation to pharyngeal skin mucosa after pharyngeal, promote the circulation of its blood capillary to accelerate its absorption to effective ingredient in medicinal liquid.
The present invention in use, is coated on ointment patient's throat position, after 1-2 minute, gargles with clear water, and the order of severity that can look the state of an illness determines frequency of utilization, when serious, can use once every one to two hour.
Beneficial effect: the present invention is by selecting suitable medical material to make medicated powder, and become paste to be coated on patient's throat with accessory drugs concentrate mix, make the medicine long period directly act on patient part, play the effect of quickly alleviating pain detumescence, and the thing such as the Pericarpium Citri tangerinae wherein containing, Herba Menthae, Radix Glycyrrhizae, all there is the effect of pathogenic fire reducing antiinflammatory, the treatment of pharyngitis is played to positive assosting effect.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.The present invention's herbal component used all can obtain from each medium-height grass pharmacy.
Embodiment 1
A kind of coating cream for the treatment of pharyngitis, the paste forming according to the weight ratio mix of 1:1.5 for principal agent and accessory drugs concentrate, wherein, the ratio that principal agent is 12:3:2:3:6:8 by Herba Menthae, flower of Fructus Momordicae, leaf of Caulis et Folium Abri, Flos Chrysanthemi Indici, Radix Glycyrrhizae and Fructus Trichosanthis according to weight ratio is mixed rear pulverizing and is obtained, and accessory drugs concentrated solution is in 15% saline, after infusion, to filter out solid matter to obtain in mass concentration after being mixed according to the ratio of weight ratio 1:3:2:2:3 by rice root palpus, Ziziphi Spinosae, pomelo peel, Pericarpium Citri tangerinae and Fructus Fici as accessory drugs.
Be more than the basic embodiment of the present embodiment, can on above basis, do further improvement or restriction:
The medicated powder fineness that described principal agent is worn into is no more than 100 orders;
In described accessory drugs concentrated solution, accessory drugs and the salt water weight ratio adding are 1:7, and the infusion gross weight that finishes rear surplus materials is 2 times of accessory drugs initial weight;
The preparation method of the coating cream of above-mentioned treatment pharyngitis, comprises the following steps:
1) preparation of principal agent medicated powder
Get Herba Menthae, flower of Fructus Momordicae, leaf of Caulis et Folium Abri, Flos Chrysanthemi Indici, Radix Glycyrrhizae and Fructus Trichosanthis according to weight ratio and wear into fineness after dry and be no more than 100 object powder, for subsequent use;
2) producing of accessory drugs concentrate
Take accessory drugs according to weight ratio, and after being mixed, put in infusion vessel, after the saline that the mass concentration that adds wherein 7 times of accessory drugs weight is 15%, make to boil with high heat, use again slow fire infusion instead, until the weight of the interior residue of vessel becomes 2 times of accessory drugs initial weight, then stop heating, the liquid that after natural cooling, filtration solids wherein obtains is accessory drugs concentrate, for subsequent use;
3) mix becomes cream
In the medicated powder making to step 1), adding step 2) mix becomes paste to obtain product after the accessory drugs concentrate produced, and the weight ratio of medicated powder and accessory drugs concentrate is 1:1.5.
Embodiment 2
A kind of coating cream for the treatment of pharyngitis, the paste forming according to the weight ratio mix of 1:3 for principal agent and accessory drugs concentrate, wherein, the ratio that principal agent is 14:5:4:5:7:9 by Herba Menthae, flower of Fructus Momordicae, leaf of Caulis et Folium Abri, Flos Chrysanthemi Indici, Radix Glycyrrhizae and Fructus Trichosanthis according to weight ratio is mixed rear pulverizing and is obtained, and accessory drugs concentrated solution is in 15% saline, after infusion, to filter out solid matter to obtain in mass concentration after being mixed according to the ratio of weight ratio 1:4:3:4:5 by rice root palpus, Ziziphi Spinosae, pomelo peel, Pericarpium Citri tangerinae and Fructus Fici as accessory drugs.
Be more than the basic embodiment of the present embodiment, can on above basis, do further improvement or restriction:
The medicated powder fineness that described principal agent is worn into is no more than 100 orders;
In described accessory drugs concentrated solution, accessory drugs and the salt water weight ratio adding are 1:9, and the infusion gross weight that finishes rear surplus materials is 3 times of accessory drugs initial weight;
The preparation method of the coating cream of above-mentioned treatment pharyngitis, comprises the following steps:
1) preparation of principal agent medicated powder
Get Herba Menthae, flower of Fructus Momordicae, leaf of Caulis et Folium Abri, Flos Chrysanthemi Indici, Radix Glycyrrhizae and Fructus Trichosanthis according to weight ratio and wear into fineness after dry and be no more than 100 object powder, for subsequent use;
2) producing of accessory drugs concentrate
Take accessory drugs according to weight ratio, and after being mixed, put in infusion vessel, after the saline that the mass concentration that adds wherein 9 times of accessory drugs weight is 15%, make to boil with high heat, use again slow fire infusion instead, until the weight of the interior residue of vessel becomes 3 times of accessory drugs initial weight, then stop heating, the liquid that after natural cooling, filtration solids wherein obtains is accessory drugs concentrate, for subsequent use;
3) mix becomes cream
In the medicated powder making to step 1), adding step 2) mix becomes paste to obtain product after the accessory drugs concentrate produced, and the weight ratio of medicated powder and accessory drugs concentrate is 1:3.
Embodiment 3
A kind of coating cream for the treatment of pharyngitis, the paste forming according to the weight ratio mix of 1:2.3 for principal agent and accessory drugs concentrate, wherein, the ratio that principal agent is 13:4:3:4:6.5:8.5 by Herba Menthae, flower of Fructus Momordicae, leaf of Caulis et Folium Abri, Flos Chrysanthemi Indici, Radix Glycyrrhizae and Fructus Trichosanthis according to weight ratio is mixed rear pulverizing and is obtained, and accessory drugs concentrated solution is in 15% saline, after infusion, to filter out solid matter to obtain in mass concentration after being mixed according to the ratio of weight ratio 1:3.5:2.5:3:4 by rice root palpus, Ziziphi Spinosae, pomelo peel, Pericarpium Citri tangerinae and Fructus Fici as accessory drugs.
Be more than the basic embodiment of the present embodiment, can on above basis, do further improvement or restriction:
The medicated powder fineness that described principal agent is worn into is no more than 100 orders;
In described accessory drugs concentrated solution, accessory drugs and the salt water weight ratio adding are 1:8, and the infusion gross weight that finishes rear surplus materials is 2.5 times of accessory drugs initial weight;
The preparation method of the coating cream of above-mentioned treatment pharyngitis, comprises the following steps:
1) preparation of principal agent medicated powder
Get Herba Menthae, flower of Fructus Momordicae, leaf of Caulis et Folium Abri, Flos Chrysanthemi Indici, Radix Glycyrrhizae and Fructus Trichosanthis according to weight ratio and wear into fineness after dry and be no more than 100 object powder, for subsequent use;
2) producing of accessory drugs concentrate
Take accessory drugs according to weight ratio, and after being mixed, put in infusion vessel, after the saline that the mass concentration that adds wherein 8 times of accessory drugs weight is 15%, make to boil with high heat, use again slow fire infusion instead, until the weight of the interior residue of vessel becomes 2.5 times of accessory drugs initial weight, then stop heating, the liquid that after natural cooling, filtration solids wherein obtains is accessory drugs concentrate, for subsequent use;
3) mix becomes cream
In the medicated powder making to step 1), adding step 2) mix becomes paste to obtain product after the accessory drugs concentrate produced, and the weight ratio of medicated powder and accessory drugs concentrate is 1:2.3.
test survey data
Using this product as laboratory sample, in 5 months, 113 acute/chronic pharyngitis patients are treated.
Therapeutic Method: plaster is coated on to patient's throat position, gargled after 1-2 minute with clear water, the order of severity that can look the state of an illness determines frequency of utilization, can use once every one to two hour when serious;
Effect standard:
Effective: in 12-24 hour, pharyngitis disease is obviously eliminated, for effective;
Effective: in 24-36 hour, pharyngitis disease is obviously eliminated, for effectively;
Invalid: exceed 36 hours, pharyngitis disease is not eliminated, for invalid;
By statistics, result is: effective 71 examples, account for total patient's 63%; Effective 37 examples, account for total patient's 33%; Invalid 5 examples, total patient's 4%;
That is to say that it is 96% that product of the present invention was cured the success rate of pharyngitis in 36 hours.
Model case:
1, Chen, man, 30 years old, acute pharyngitis, the front throat of use swells and ache, dysphagia, occurs hoarse; Used a deuterzooid product every one hour, after 11 hours, swell and ache and obviously disappear, after 16 hours, cure;
2, Zhao, female, 26 years old, acute pharyngitis, used front throat pain, swallows saliva difficulty; Used a deuterzooid product every 2 hours, after 10 hours, symptom obviously disappears;
3, grandson, female, 53 years old, chronic pharyngitis, pharyngeally before using dryly itched, distending pain, uses a deuterzooid product every 4 hours, swells and ache and obviously disappear after 13 hours, after 20 hours, cures;
4, favour, man, 19 years old, chronic pharyngitis, pharyngeally before using dryly itched, distending pain, and has foreign body sensation, uses a deuterzooid product every 3 hours, and after 17 hours, above-mentioned symptom obviously disappears, and after 28 hours, cures;
5, Lee, man, 25 years old, acute pharyngitis, the front throat of use swells and ache, dysphagia, uses a deuterzooid product every 3 hours, and after 26 hours, above-mentioned symptom obviously disappears, and after 33 hours, cures.
Claims (4)
1. treat the coating cream of pharyngitis for one kind, it is characterized in that: the paste forming according to the weight ratio mix of 1:1.5-3 for principal agent and accessory drugs concentrate, wherein, principal agent is by Herba Menthae, flower of Fructus Momordicae, leaf of Caulis et Folium Abri, Flos Chrysanthemi Indici, the ratio that Radix Glycyrrhizae and Fructus Trichosanthis are 12-14:3-5:2-4:3-5:6-7:8-9 according to weight ratio is mixed rear pulverizing and is obtained, accessory drugs concentrated solution must by the rice root as accessory drugs, Ziziphi Spinosae, pomelo peel, Pericarpium Citri tangerinae and Fructus Fici are in 15% saline, after infusion, to filter out solid matter to obtain in mass concentration after mixing according to the ratio of weight ratio 1:3-4:2-3:2-4:3-5.
2. a kind of coating cream for the treatment of pharyngitis according to claim 1, is characterized in that: the medicated powder fineness that described principal agent is worn into is no more than 100 orders.
3. a kind of coating cream for the treatment of pharyngitis according to claim 1, is characterized in that: in described accessory drugs concentrated solution, accessory drugs and the salt water weight ratio adding are 1:7-9, and the infusion gross weight that finishes rear surplus materials be accessory drugs initial weight 2-3 doubly.
4. the preparation method of the coating cream for the treatment of pharyngitis according to claim 1, is characterized in that, comprises the following steps:
1) preparation of principal agent medicated powder
Get Herba Menthae, flower of Fructus Momordicae, leaf of Caulis et Folium Abri, Flos Chrysanthemi Indici, Radix Glycyrrhizae and Fructus Trichosanthis according to weight ratio and wear into fineness after dry and be no more than 100 object powder, for subsequent use;
2) producing of accessory drugs concentrate
Take accessory drugs according to weight ratio, and after being mixed, put in infusion vessel, after adding wherein the saline that accessory drugs weight 7-9 mass concentration is doubly 15%, make to boil with high heat, use again slow fire infusion instead, until the weight of the interior residue of vessel becomes 2-3 times of accessory drugs initial weight, then stop heating, the liquid that after natural cooling, filtration solids wherein obtains is accessory drugs concentrate, for subsequent use;
3) mix becomes cream
In the medicated powder making to step 1), adding step 2) mix becomes paste to obtain product after the accessory drugs concentrate produced, and the weight ratio of medicated powder and accessory drugs concentrate is 1:1.5-3.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410262583.5A CN104001060A (en) | 2014-06-13 | 2014-06-13 | Coating ointment for treating pharyngitis and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410262583.5A CN104001060A (en) | 2014-06-13 | 2014-06-13 | Coating ointment for treating pharyngitis and preparation method thereof |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101385828A (en) * | 2008-09-18 | 2009-03-18 | 李爱英 | Traditional Chinese medicine for treating urgent and chronic inflammation of upper respiratory tract |
| CN102380028A (en) * | 2010-08-25 | 2012-03-21 | 蔡英杰 | Medicament for treating child antiadoncus |
-
2014
- 2014-06-13 CN CN201410262583.5A patent/CN104001060A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101385828A (en) * | 2008-09-18 | 2009-03-18 | 李爱英 | Traditional Chinese medicine for treating urgent and chronic inflammation of upper respiratory tract |
| CN102380028A (en) * | 2010-08-25 | 2012-03-21 | 蔡英杰 | Medicament for treating child antiadoncus |
Non-Patent Citations (3)
| Title |
|---|
| 周凌等: "中医药治疗急性咽炎的临床研究进展", 《中医药学报》 * |
| 张钢军等: "中药喷喉治疗急性咽炎200例", 《河北中西医结合杂志》 * |
| 覃冬云等: "中药复方制剂园丁糖治疗咽喉炎的临床观察", 《中国中药杂志》 * |
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Application publication date: 20140827 |
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