CN103989909A - Traditional Chinese medicine oral liquid for treating asthma and preparation method thereof - Google Patents

Abstract

The invention discloses traditional Chinese medicine oral liquid for treating asthma and a preparation method thereof. The traditional Chinese medicine oral liquid is prepared from the following raw materials in parts by weight: 25 to 35 parts of radix pseudostellariae, 15 to 25 parts of radix bupleuri, 12 to 24 parts of dessert almond, 20 to 30 parts of bulbus fritillariae cirrhosae, 11 to 19 parts of rhizoma atractylodis macrocephalae, 16 to 28 parts of rorippa indica, 20 to 30 parts of ephedra, 13 to 21 parts of peach kernel, 10 to 15 parts of radix asteris, 17 to 26 parts of herba ardisiae japonicae, 22 to 28 parts of flos farfarae, 26 to 34 parts of herba epimedii, 15 to 20 parts of morii hayata, 10 to 15 parts of poria cocos, 14 to 22 parts of rhus chinensis mill, 24 to 32 parts of persimmon leaf, 10 to 15 parts of affine cudweed, 35 to 45 parts of saccharose, and proper amount of water. The oral liquid has the effects of clearing heat and dissipating phlegm, relieving cough and asthma, supporting the healthy energy, relieving sore-throat and clearing away the lung-heat, tonifying Qi and reinforcing kidney, warming lung and relieving asthma, and moistening lung and depressing Qi, can effectively treat asthma, and has the characteristics of treating both symptoms and root causes, being fast to act, obvious in treatment effect and high in recovery rate, greatly avoiding recurrence, and being free of toxic and side effects, safe and reliable, and convenient to take.

Description

A kind of Chinese medicine oral liquid for the treatment of asthma and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine oral liquid, be specifically related to a kind of Chinese medicine oral liquid for the treatment of asthma.

Background technology

Asthma is a kind of dyspnea of outbreak repeatedly the chronic anaphylaxis disease with the sound of stridulating, and belongs to the traditional Chinese medical science " asthma " category.It occurs many because of latent phlegm retaining in the lung, is added with the factors such as diseases caused by exogenous pathogenic factor, diet, feelings will, overstrain, so that stagnation of phlegm air flue, due to abnormal rising of lung-QI.Clinical dividing stage of attack and catabasis.Stage of attack, is divided again cold asthma and heat asthma.Catabasis is weak owing to breathing heavily for a long time, causes spleen, insufficiency of lung-QI, even occurs suffering from a deficiency of the kidney.The Chinese medicine preparation that is used for the treatment of in the market above-mentioned symptom is of a great variety, but the shortcoming that ubiquity uncertain therapeutic efficacy is cut, taken effect slowly, easily recurs is cured the symptoms, not the disease.

Summary of the invention

In order to overcome the shortcoming of prior art, the object of the present invention is to provide a kind for the treatment of both the principal and secondary aspects of a disease, instant effect, evident in efficacy, cure rate is high, the Chinese medicine oral liquid of the treatment asthma of non-relapse after healing and preparation method thereof.

For achieving the above object, the technical solution used in the present invention is as follows:

Treat a Chinese medicine oral liquid for asthma, made by the raw material of following weight portion: Radix Pseudostellariae 25-35, Radix Bupleuri 15-25, Semen pruni armeniacae 12-24, Bulbus Fritillariae Cirrhosae 20-30, Rhizoma Atractylodis Macrocephalae 11-19, Herba Rorippae 16-28, Herba Ephedrae 20-30, Semen Persicae 13-21, Radix Asteris 10-15, Herba Ardisiae Japonicae 17-26, Flos Farfarae 22-28, Herba Epimedii 26-34, Flos Luffae 15-20, Poria 10-15, Fructus rhois chinensis 14-22, Folium Kaki 24-32, Herba Gnaphalii Affinis 10-15, sucrose 35-45, water are appropriate.

Preferably, treat a Chinese medicine oral liquid for asthma, made by the raw material of following weight portion: Radix Pseudostellariae 30, Radix Bupleuri 20, Semen pruni armeniacae 18, Bulbus Fritillariae Cirrhosae 25, the Rhizoma Atractylodis Macrocephalae 16, Herba Rorippae 24, Herba Ephedrae 25, Semen Persicae 17, Radix Asteris 12, Herba Ardisiae Japonicae 23, Flos Farfarae 26, Herba Epimedii 32, Flos Luffae 18, Poria 12, Fructus rhois chinensis 17, Folium Kaki 28, Herba Gnaphalii Affinis 12, sucrose 40, water are appropriate.

The preparation method of the Chinese medicine oral liquid for the treatment of asthma of the present invention, comprises the following steps:

(1) get Radix Bupleuri, Semen pruni armeniacae, the Rhizoma Atractylodis Macrocephalae, Semen Persicae, Flos Farfarae, Herba Gnaphalii Affinis mix homogeneously, pulverized 30-50 mesh sieve, add 5-10 times of water gaging, reflux 1-2h, collects after first distillate, and redistillation 0.5-1h, merges distillate, and extraction volatile oil is stand-by;

(2) Chinese crude drug mix homogeneously under remainder, pulverized 40-60 mesh sieve, decocted with water and extracted 2 times, 8-12 times of water gaging for the first time, adds 4-8 times of water gaging for the second time, decocts 1-2h at every turn, merge decoction liquor, filter, it is 1.14-1.18 that filtrate is concentrated into relative density, then add 80% ethanol make containing alcohol amount be 50-60%, cold preservation leaves standstill 36-48h, get supernatant decompression recycling ethanol, be concentrated into relative density and be 1.15-1.20, stand-by;

(3) get sucrose and make syrup, the volatile oil making with step (1) merges, stir evenly, then the concentrated solution that adds step (2) to make, the standardize solution that adds water, stirs evenly, filters, and fill, sterilizing, to obtain final product.

Usage and consumption: oral, a 10ml, 2-3 time on the one.

Beneficial effect of the present invention:

Oral liquid of the present invention has effect of removing heat-phlegm, relieving cough and asthma, strengthening the body resistance, sore-throat relieving lung heat clearing, vital energy benefiting and the kidney invigorating, warming the lung Dingchuan, lung moistening sending down the abnormal ascending QI, can effectively treat asthma, and there is treating both the principal and secondary aspects of a disease, instant effect, evident in efficacy, cure rate is high, non-relapse after healing, the feature that has no side effect, safe and reliable, taking convenience.

Detailed description of the invention

Treat a Chinese medicine oral liquid for asthma, made by the raw material of following weight (g): Radix Pseudostellariae 25, Radix Bupleuri 15, Semen pruni armeniacae 12, Bulbus Fritillariae Cirrhosae 20, the Rhizoma Atractylodis Macrocephalae 11, Herba Rorippae 16, Herba Ephedrae 20, Semen Persicae 13, Radix Asteris 10, Herba Ardisiae Japonicae 17, Flos Farfarae 22, Herba Epimedii 26, Flos Luffae 15, Poria 10, Fructus rhois chinensis 14, Folium Kaki 24, Herba Gnaphalii Affinis 10, sucrose 35, water are appropriate.

The preparation method of the Chinese medicine oral liquid for the treatment of asthma, comprises the following steps:

(1) get Radix Bupleuri, Semen pruni armeniacae, the Rhizoma Atractylodis Macrocephalae, Semen Persicae, Flos Farfarae, Herba Gnaphalii Affinis mix homogeneously, pulverized 40 mesh sieves, add 7 times of water gagings, reflux 1.5h, collects after first distillate, and redistillation 1h, merges distillate, and extraction volatile oil is stand-by;

(2) Chinese crude drug mix homogeneously under remainder, pulverized 50 mesh sieves, decocted with water and extracted 2 times, 10 times of water gagings for the first time, add 6 times of water gagings for the second time, decoct 1.5h at every turn, merge decoction liquor, filter, it is 1.16 that filtrate is concentrated into relative density, then add 80% ethanol make containing alcohol amount be 55%, cold preservation leaves standstill 48h, get supernatant decompression recycling ethanol, be concentrated into relative density and be 1.18, stand-by;

(3) get sucrose and make syrup, the volatile oil making with step (1) merges, stir evenly, then the concentrated solution that adds step (2) to make, the standardize solution that adds water, stirs evenly, filters, and fill, sterilizing, to obtain final product.

Embodiment 2

Treat a Chinese medicine oral liquid for asthma, made by the raw material of following weight (g): Radix Pseudostellariae 30, Radix Bupleuri 20, Semen pruni armeniacae 18, Bulbus Fritillariae Cirrhosae 25, the Rhizoma Atractylodis Macrocephalae 16, Herba Rorippae 24, Herba Ephedrae 25, Semen Persicae 17, Radix Asteris 12, Herba Ardisiae Japonicae 23, Flos Farfarae 26, Herba Epimedii 32, Flos Luffae 18, Poria 12, Fructus rhois chinensis 17, Folium Kaki 28, Herba Gnaphalii Affinis 12, sucrose 40, water are appropriate.

Preparation method is with embodiment 1.

Embodiment 3

Treat a Chinese medicine oral liquid for asthma, Radix Pseudostellariae 5, Radix Bupleuri 25, Semen pruni armeniacae 24, Bulbus Fritillariae Cirrhosae 30, the Rhizoma Atractylodis Macrocephalae 19, Herba Rorippae 28, Herba Ephedrae 30, Semen Persicae 21, Radix Asteris 15, Herba Ardisiae Japonicae 26, Flos Farfarae 28, Herba Epimedii 34, Flos Luffae 20, Poria 15, Fructus rhois chinensis 22, Folium Kaki 32, Herba Gnaphalii Affinis 15, sucrose 45, water are appropriate.

Preparation method is with embodiment 1.

model case:

Case 1: Liu, female, 58 years old, first visit on October 23 in 2012.Patient's asthma is shown effect more than 10 years repeatedly, increases the weight of February.Burst asthma before patient more than 10 years, opening mouth and lifting shoulder due to dyspnea very time, can not put down sleepingly, and medical in local hospital, anaphylactogen experiment prompting, to many kinds of substance allergy such as dust, hair, tobacco and wine, gives after the medicine symptomatic treatments such as Wan Tuolin, and symptom can slightly be alleviated; But asthma is shown effect repeatedly since then, often increase the weight of easy catching a cold in autumn and winter season and night.February, cause entered to be after autumn affected by the cold, and causes asthma increase the weight of by flu.Examine quarter: pant frequent, moving breathe heavily very, septum pectorale is felt oppressed, and Nocturnal increases the weight of to be difficult to fall asleep, and cough, coughs up a large amount of weak yellow foam sample expectorant, and nose flows a large amount of yellow thick nasal discharge, aversion to cold and cold limbs, back part is bitterly stiff, receive can, sleep poor, loose stool, urine can, lower limb are without edema.Light red tongue, yellow and greasy fur, deep-thready pulse.Tcm diagnosis: asthma.Belong to accumulation of phlegm-heat in the lung, lung spleen is suffered from a deficiency of the kidney, the rule for the treatment of: removing heat-phlegm, relieving cough and asthma, strengthening the body resistance.So taken oral liquid of the present invention, to take after one month, symptoms of asthma obviously alleviates, and continues to take after two months, and symptoms of asthma all disappears, without the disease of discomfort, recovery from illness.After 1 year, follow up a case by regular visits to not recurrence.

Case 2: grandson so-and-so, female, 42 years old, first visit on February 14 in 2013.Patient suffers from discontinuity asthma more than 5 years, increases the weight of more than February.Winter or cold outbreak whenever, cause was caught cold and brought out asthma February, and rapid breathing is moving more so, gurgling with sputum, chest and diaphragm is full vexed, coughs thin and whitish sputum, shortness of breath and fatigue, soreness of the waist and knees, loose stool is thin greatly, and every day, twice or thrice light red tongue was dark, and white, slippery and moist fur is greasy, thready and rolling pulse.Physical examination: respiratory harshness, at base of lung audible and wheezing sound, do not hear and moist rale.Western medicine diagnose: bronchial asthma.Tcm diagnosis: cold asthma (stage of attack), card belongs to wind-cold tightening the lung, stagnation of phlegm blood stasis, spleen deficiency of kidney-QI.Control with warming lung for dispelling cold dissipating phlegm and removing blood stasis, relieving cough and asthma, improving inspiration by invigorating the kidney.So taken oral liquid of the present invention, after taking medicine 20 days, to pant, gurgling with sputum, all diseases of expectoration successively decrease, large loose stool is thin, every day one twice, light red tongue is and dark, and tongue is slightly greasy in vain, stringy and thready pulse, following the service after 30 days cough with asthma, rale gradually flat, stool is shaped, once a day, accidental twice, light red tongue, white and thin fur, arteries and veins is string slightly.After 1 year, follow up a case by regular visits to not recurrence.

Case 3: Wu so-and-so, man, 28 years old, December in 2012 first visit on the 24th.More than main suit's asthma February, patient just has asthma medical history 15 years from little, and all important criminal several times, apply the treatments such as various antibiotic, antiallergic agent, anti-asthmatic and aerosol so far, but effect is not remarkable, therefore carry out here Chinese traditional treatment always every year.Examine quarter: patient's asthma begins to show effect whole night every afternoon, and can not sleep night, is seat, has rale, and companion's greenish-yellow complexion, becomes thin, and spirit is poor; The morning, chest was felt oppressed, moving breathe hard, and cough expectorant is few unfavorable, itching throat, easily diseases caused by exogenous pathogenic factor; Two fullness of the lung cloth wheezing sounds, yellow and greasy fur, red tongue, deep-thready pulse.The rule for the treatment of: lung deficiency of defensive qi, stagnation of phlegm cough with asthma; Suitable QI invigorating depressed lung-energy dispersing, clearing away heat and eliminating phlegm cough-relieving.So taken oral liquid of the present invention, take medicine after 30 days, breathe heavily aobvious subtracting, sleep, can put down sleepingly, cough is aobvious to be subtracted, yellow and greasy fur, deep-thready pulse, continues to take after 40 days without panting, and two lungs, without wheezing sound, are slept, in high spirits, malaise symptoms disappearance, yellow and thin fur, thready pulse.After 1 year, follow up a case by regular visits to not recurrence.

Claims (3)

1. treat the Chinese medicine oral liquid of asthma for one kind, it is characterized in that, made by the raw material of following weight portion: Radix Pseudostellariae 25-35, Radix Bupleuri 15-25, Semen pruni armeniacae 12-24, Bulbus Fritillariae Cirrhosae 20-30, Rhizoma Atractylodis Macrocephalae 11-19, Herba Rorippae 16-28, Herba Ephedrae 20-30, Semen Persicae 13-21, Radix Asteris 10-15, Herba Ardisiae Japonicae 17-26, Flos Farfarae 22-28, Herba Epimedii 26-34, Flos Luffae 15-20, Poria 10-15, Fructus rhois chinensis 14-22, Folium Kaki 24-32, Herba Gnaphalii Affinis 10-15, sucrose 35-45, water are appropriate.

2. a kind of Chinese medicine oral liquid for the treatment of asthma according to claim 1, it is characterized in that, made by the raw material of following weight portion: Radix Pseudostellariae 30, Radix Bupleuri 20, Semen pruni armeniacae 18, Bulbus Fritillariae Cirrhosae 25, the Rhizoma Atractylodis Macrocephalae 16, Herba Rorippae 24, Herba Ephedrae 25, Semen Persicae 17, Radix Asteris 12, Herba Ardisiae Japonicae 23, Flos Farfarae 26, Herba Epimedii 32, Flos Luffae 18, Poria 12, Fructus rhois chinensis 17, Folium Kaki 28, Herba Gnaphalii Affinis 12, sucrose 40, water are appropriate.

3. a preparation method for the Chinese medicine oral liquid for the treatment of asthma as claimed in claim 1 or 2, is characterized in that comprising the following steps:

(1) get Radix Bupleuri, Semen pruni armeniacae, the Rhizoma Atractylodis Macrocephalae, Semen Persicae, Flos Farfarae, Herba Gnaphalii Affinis mix homogeneously, pulverized 30-50 mesh sieve, add 5-10 times of water gaging, reflux 1-2h, collects after first distillate, and redistillation 0.5-1h, merges distillate, and extraction volatile oil is stand-by;

(2) Chinese crude drug mix homogeneously under remainder, pulverized 40-60 mesh sieve, decocted with water and extracted 2 times, 8-12 times of water gaging for the first time, adds 4-8 times of water gaging for the second time, decocts 1-2h at every turn, merge decoction liquor, filter, it is 1.14-1.18 that filtrate is concentrated into relative density, then add 80% ethanol make containing alcohol amount be 50-60%, cold preservation leaves standstill 36-48h, get supernatant decompression recycling ethanol, be concentrated into relative density and be 1.15-1.20, stand-by;

(3) get sucrose and make syrup, the volatile oil making with step (1) merges, stir evenly, then the concentrated solution that adds step (2) to make, the standardize solution that adds water, stirs evenly, filters, and fill, sterilizing, to obtain final product.