CN103989789A - Traditional Chinese medicine dropping liquid for treating tympanitis and preparation method thereof - Google Patents

Traditional Chinese medicine dropping liquid for treating tympanitis and preparation method thereof Download PDF

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CN103989789A
CN103989789A CN201410235981.8A CN201410235981A CN103989789A CN 103989789 A CN103989789 A CN 103989789A CN 201410235981 A CN201410235981 A CN 201410235981A CN 103989789 A CN103989789 A CN 103989789A
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chinese medicine
traditional chinese
medicine dropping
otitis media
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CN103989789B (en
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高广忠
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Anhui Muchuntang Natural Medicine Research And Development Co ltd
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Abstract

The invention relates to traditional Chinese medicine preparations and particularly relates to traditional Chinese medicine dropping liquid for treating tympanitis and a preparation method thereof. The traditional Chinese medicine dropping liquid is prepared from the following traditional Chinese medicine raw materials in parts by weight: 15-20 parts of coptis root, 5-10 parts of mint, 5-10 parts of borneol, 6-8 parts of natural indigo, 1-2 parts of frankincense, 3-5 parts of astragalus root, 1-2 parts of dragon bone, 3-5 parts of honeysuckle flower, 1-2 parts of phellodendron bark, 3-5 parts of cicada slough and 100-150 parts of balsam. The preparation method comprises the steps of immersing coptis roots, mints, natural indigos, frankincense, astragalus roots, dragon bones, honeysuckle flowers, phellodendron barks and cicada sloughs into the balsam, sealing for keeping, and standing at a shady and cool place for 36-48 hours; then, transferring the medicines into a pot, and heating for 10-15 minutes with soft fire; finally, filtrating residues, adding the borneol into a filtrate, and dissolving the borneol, thereby obtaining the traditional Chinese medicine dropping liquid for treating tympanitis. The traditional Chinese medicine dropping liquid for treating tympanitis and the preparation method thereof have the advantages that the used traditional Chinese medicines are safe and reliable; all the medicines are harmonized, so that the traditional Chinese medicine dropping liquid has the effects of clearing away heat and toxic materials, drying dampness and removing pus, removing necrosis and promoting granulation, and counteracting evil force and assuaging pain, and has the characteristics of definite treatment effect, high effect taking speed, high cure rate, no side effect and the like during the treatment of tympanitis.

Description

A kind of Chinese medicine dropping for the treatment of otitis media and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine dropping for the treatment of otitis media and preparation method thereof.
Background technology
Otitis media, is commonly called as " rotten ear ", is the inflammation of mucosa of tympanic cavity.Pathogenic bacteria enters tympanum, and when resistance weakens or just produces inflammation when bacteriotoxin strengthens, it shows as, and in ear pain (increase the weight of night), heating, aversion to cold, bitter taste, urine are red or yellow, constipation, auditory dysesthesia etc.As the perforation of ear drum, in ear can flow out pus, and pain can alleviate, and normal and chronic mastoiditis exists simultaneously.Acute stages treated is not thorough, can change chronic otitis media into, with body constitution, climate change, the in ear liquid of can regularly suppurating, time few when many, delay is for many years.The traditional Chinese medical science is called primary disease " otopyosis ", " chronic suppurative otitis media ", thinks because of prevailing the causing of dampness-heat in the liver and gallbladder (fire) pathogen.
Otitis media is the inflammatory lesion of involving all or part of structure of middle ear (comprising pharyngotympanic tube, tympanum, tympanic antrum and mastoid air cell), is apt to occur in child.Can be divided into apyetous and suppurative two large classes.Apyetous person comprises secretory otitis media, barotraumatic otits media etc., and suppurative person has acute and chronic dividing.Specificity inflammation is shown in very little, as tuberculous otitis media etc.
Wherein, suppurative otitis media comprises:
(1) acute suppurative otitis media: infected the otitis media causing by suppurative bacterium, its symptom is mainly otalgia, suppurates.Children's's General Symptoms is more obvious than adult, can have heating, vomiting etc.Serious complication has intracranial complication, as meningitis, brain abscess etc.Other complication have labyrinthitis, facial paralysis etc.
(2) chronic suppurative otitis media: refer to middle-ear mucosa, periosteum or deeply reach the chronic suppurative inflammation of sclerotin.Primary disease is comparatively common clinically, is often interrupted or persistence is suppurated, the perforation of ear drum, auditory dysesthesia be as main clinical manifestation taking in ear, when serious, can cause the complication outside intracranial, cranium.1. General Symptoms: weight differs.Can be afraid of cold, heating, weak, loss of appetite.Children's's General Symptoms is heavier, the symptoms of digestive tract such as normal companion vomiting, diarrhoea.Once tympanum perforation, body temperature decline gradually, and General Symptoms obviously alleviates.2. otalgia: ear deep pain, increases the weight of gradually.As pulsation jumping pain or twinge, can be to homonymy head or tooth radiation.When swallowing and coughing, otalgia increases the weight of, and violent person is unable to fall asleep night for otalgia, dysphoria.After the perforation of ear drum is suppurated, otalgia is paused and is subtracted.3. discharging ear: be the cardinal symptom of primary disease, can be mucus, glutinous pus or pure purulence.Non-dangerous type is suppurated thinner, odorless.Though dangerous type is suppurated seldom, thicker, mostly is pure purulence, and with foreign odor taste.4. auditory dysesthesia and tinnitus: start to feel ear vexed, the audition that continues is gradually fallen, companion's tinnitus.Otalgia play person deafness can be left in the basket.Some patient can vertigo, and after perforation, deafness alleviates on the contrary.5. deaf: weight differs, because being mostly monaural morbidity, easily out in the cold, be generally conductive deafness.
Non-suppurative otitis media can cause following disease:
(1) auditory dysesthesia: when acute secretory otitis media mostly can decline rear in flu, by air, by plane or dive under water, occur auditory dysesthesia, can have " strengthening from sound " phenomenon.The order of severity of otitis media,secretory,chronic patient's deafness often has fluctuation.When compressing tragus or head position change, audition can make moderate progress, and when middle ear effusion is sticky, audition can not change because of the variation of head position.The many main suits without auditory dysesthesia of child, show as father and mother's call are ignored, absent minded, or require excessive volume while seeing TV.(2) otalgia: can have slight otalgia when acute secretory otitis media, otitis media,secretory,chronic is many can occur otalgia in the time of secondary infection.(3) the vexed swollen sense of in ear or inaccessible sense.(4) tinnitus: generally heavy, can be intermittence, when head movement, yawn or audible and gur gling when blowing the nose.Also can there is in ear flowing water in minority patients with secretory otitis media, but the persistent period is very short, is only about a few hours or 1 day.(5) otoscopy: acute stage tympanum periphery have radial stria vascularis.Pars tensa membranae tympani caves in, and shows as light cone and shortens, is out of shape or disappear; Manubrium of malleus backward, top displacement; Short process of malleus evagination is obvious.When hydrotympanum, tympanum loses normal gloss, is yellowish, orange red or amber; Chronic person's tympanum milky or dusty blue are opaque.If secretions is serosity, and underfill tympanum, can see through tympanum and see fluid level, be concave upright curved line, see through tympanum and sometimes can see bubble, after pharyngotympanic tube catheterization, bubble increases; If in tympanum, hydrops is many, tympanum evagination, tympanum limited range of motion.
At present, the Western medicine for the treatment of otitis media is a lot, but most drug therapeutic effect is poor, and also has the shortcomings such as treatment cost is high, side effect is large, even affects patient health when serious.In addition, also have the Chinese medicine of a lot for the treatment of otitis media, but the shortcoming such as great majority have that therapeutic effect is poor, cure rate is low and treatment cycle is long.
Summary of the invention
According to above the deficiencies in the prior art, the invention provides a kind of Chinese medicine dropping for the treatment of otitis media and preparation method thereof, it is evident in efficacy, safe and reliable, have no side effect, and has wide potential applicability in clinical practice.
A kind of Chinese medicine dropping for the treatment of otitis media of the present invention, according to parts by weight meter, be prepared from by following raw material of Chinese medicine: 100~150 parts of 15~20 parts of Rhizoma Coptidis, 5~10 parts of Herba Menthaes, 5~10 parts of Borneolum Syntheticums, 6~8 parts of Indigo Naturaliss, 1~2 part of Olibanum, 3~5 parts of the Radixs Astragali, 1~2 part of Os Draconis, 3~5 parts of Flos Loniceraes, 1~2 part of Cortex Phellodendri, 3~5 parts of Periostracum Cicadaes and Oleum sesami.
Wherein, preferred version is as follows:
According to parts by weight meter, be prepared from by following raw material of Chinese medicine: 120 parts of 20 parts of Rhizoma Coptidis, 10 parts of Herba Menthaes, 8 parts of Borneolum Syntheticums, 6 parts of Indigo Naturaliss, 1 part of Olibanum, 3 parts of the Radixs Astragali, 1 part of Os Draconis, 3 parts of Flos Loniceraes, 2 parts of Cortex Phellodendris, 5 parts of Periostracum Cicadaes and Oleum sesami.
The preparation method of the Chinese medicine dropping for the treatment of otitis media of the present invention, carry out according to following steps:
(1) Rhizoma Coptidis, Herba Menthae, Indigo Naturalis, Olibanum, the Radix Astragali, Os Draconis, Flos Lonicerae, Cortex Phellodendri and Periostracum Cicadae are immersed in Oleum sesami, airtight, seal, be statically placed in 36~48 hours, shady and cool lucifuge place up for safekeeping;
(2) said medicine is transferred in pot to slow fire heating 10~15 minutes;
(3) filtration residue adds Borneolum Syntheticum in filtrate, after it is dissolved, and the Chinese medicine dropping of the otitis media that can obtain medical treatment.
The present invention in use, with 3~5 of dropper fine-stills in ear, every day three times.
Pharmacology analysis:
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.The kind clear part of the body cavity above the diaphragm housing the heart and lungs of Rhizoma Coptidis (processed with wine) is burning hot.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually damp and hot middle resistance, feeling of fullness vomiting for cold and heat.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.
Herba Menthae: function cures mainly dispelling wind, heat radiation, ward off dirty, removing toxic substances.Control affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria.
Borneolum Syntheticum: acrid in the mouth, hardship, be slightly cold; GUIXIN, liver, lung meridian; Delicate fragrance a surname is loose, has the refreshment of having one's ideas straightened out, the loose poison of heat clearing away, and effect of improving acuity of vision and removing nebula, cures mainly calentura unconsciousness due to high fever, apoplexy syncope due to accumulation of phlegm infantile convulsion, heat-damp in summer is hoodwinked key clearly, sore throat deafness, aphtha tooth is swollen, carbuncle sore infantile malnutrition hemorrhoid, conjunctival congestion and swelling pain, pterygium.
Indigo Naturalis: heat clearing away, blood cooling and ecchymoses removing, removing toxic substances, purging liver-fire, arresting convulsion.Cure mainly: control epidemic febrile disease intenseness of heat, macule, spits blood, spits blood, pediatric epilepsy scared, skin ulcer is swollen, erysipelas, snake bite and insect sting.
Olibanum: cure mainly regulating qi and activating blood, analgesic therapy, chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
The Radix Astragali: invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, diuresis, granulation promoting.For weak, the chronic diarrhea proctoptosis of the deficiency of vital energy, spontaneous perspiration, edema, sub-official's prolapsus, chronic nephritis proteinuria, diabetes, open sore part disunion of a specified duration.
Os Draconis: tranquillization with heavy prescription tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Control infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, and spontaneous sweating, seminal emission stranguria with turbid discharge, tells nosebleed and has blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time.
Flos Lonicerae: cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency and treats effect of wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.
Cortex Phellodendri: heat clearing away.Dampness, pathogenic fire purging, removing toxic substances.Control hematodiarrhoea, have loose bowels, quench one's thirst, jaundice , flaccidity of feet with lamenness, nocturnal emission, stranguria with turbid discharge, hemorrhoid, have blood in stool, also under leucorrhea, hectic fever due to YIN-deficiency consumptive fever, conjunctival congestion and swelling pain, aphtha of the mouth and tongue, sore swollen toxin.
Periostracum Cicadae: loose wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion cataracta, convulsion with spasms, tetanus.
The invention has the advantages that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.All medicine phases and have heat-clearing and toxic substances removing, dampness except pus, removing the necrotic tissue and promoting granulation and the analgesic effect that exorcises evil spirits, treatment otitis media has that determined curative effect, instant effect, cure rate are high, the feature such as have no side effect.
Curative effect judgement:
Collect 42 routine outpatient service otitis media patients, male 30 examples, female's 12 examples; Age 8-60 year, average 34 years old; The course of disease is the longest 1 year, the shortest 1 week, average about half a year.Cardinal symptom: auditory dysesthesia in various degree, the inaccessible sense of in ear; Companion's tinnitus person 15 examples, companion otalgia person 13 examples.Toposcopy: bilateral auditory meatus is without secretions, otopiesis; Visible fluid level person 19 examples, extract liquid person 23 examples out through auripuncture, and electric audiometry shows all transmission deafness in various degree, and wherein 3 examples are made myringotomy, and 1 example is made grommet insertion.All patients apply dropping liquid of the present invention and treat, and every day three times, each 3~5, are used in conjunction 10 days.Curative effect determinate standard is: effective: subjective symptoms disappears, and auditory rehabilitation is normal, and tympanum is normal, and mobility is good, and electric audiometry shows that conductance returns to normal range, lower than 15db; Effective: subjective symptoms obviously alleviates, auditory rehabilitation, tympanum activity is fair, within conductance 20-30db is shown in electric audiometry; Invalid: subjective symptoms is unchanged, toposcopy with take medicine before identical.
Result: effective 28 examples in 42 routine patients, account for 66.7%; Effective 13 examples, account for 31%; Invalid 1 example, accounts for 2.4%.Statistics total effective rate is 97.6%.
Below enumerate several model cases:
Lee, man, 8 years old, auris dextra feeling of distension and oppression stopped up sense, auditory dysesthesia, in ear has hydrodynamic(al) sense.Look into tympanum complete, cave in and be lark, auris dextra transmission deafness is shown in electric audiometry, conductance 40~45db, and row tympanum drawing liquid has yellow liquid, is diagnosed as chronic suppurative otitis media.Once made pharyngotympanic tube catheterization, and used antibiotics antiinflammatory, local physical therapy etc., have certain effect in a short time, but recurrence again soon.Adopt subsequently Chinese medicine dropping of the present invention, every day three times, each 3~5, be used in conjunction 10 days.Patient is conscious easily, and auris dextra feeling of distension and oppression stops up sense and disappears, and auditory rehabilitation is normal, and tympanum is complete, and in tympanum, without transudate, electric audiometry shows that conductance returns to below 15db.Continue to drip 10 days to consolidate curative effect, make eventually persistent ailment accuse more, follow up a case by regular visits to 2 years without recurrence.
Jiang, man, 41 years old.Ears repeated intermittent is suppurated more than 2 years, and many places are sought curing and treated, and gives penicillin, the treatment of streptomycin [Dan, and effect is poor.Check: ears are aobvious purulent secretion all, and tympanum has the central perforation of 0.3mm, see that the congested swelling companion of tympanum slightly thickens.Take the photograph sheet and show bilateral chronic simple otitis media, mastoiditis, without bone destruction.Adopt subsequently Chinese medicine dropping of the present invention, every day three times, each 3~5, treatment in continuous a week, is shown in that double auditory canal is unobstructed, and without purulent secretion, tympanum central perforation place sharp edge is not congested.Continue to drip 10 days to consolidate curative effect, make eventually persistent ailment accuse more, follow up a case by regular visits to 2 years without recurrence.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1:
A kind of Chinese medicine dropping for the treatment of otitis media, according to parts by weight meter, be prepared from by following raw material of Chinese medicine: 120 parts of 20 parts of Rhizoma Coptidis, 10 parts of Herba Menthaes, 8 parts of Borneolum Syntheticums, 6 parts of Indigo Naturaliss, 1 part of Olibanum, 3 parts of the Radixs Astragali, 1 part of Os Draconis, 3 parts of Flos Loniceraes, 2 parts of Cortex Phellodendris, 5 parts of Periostracum Cicadaes and Oleum sesami.
Embodiment 2:
A kind of Chinese medicine dropping for the treatment of otitis media, according to parts by weight meter, be prepared from by following raw material of Chinese medicine: 100 parts of 15 parts of Rhizoma Coptidis, 5 parts of Herba Menthaes, 10 parts of Borneolum Syntheticums, 8 parts of Indigo Naturaliss, 2 parts of Olibanums, 5 parts of the Radixs Astragali, 2 parts of Os Draconis, 5 parts of Flos Loniceraes, 1 part of Cortex Phellodendri, 3 parts of Periostracum Cicadaes and Oleum sesami.
Embodiment 3:
A kind of Chinese medicine dropping for the treatment of otitis media, according to parts by weight meter, be prepared from by following raw material of Chinese medicine: 150 parts of 20 parts of Rhizoma Coptidis, 8 parts of Herba Menthaes, 10 parts of Borneolum Syntheticums, 8 parts of Indigo Naturaliss, 2 parts of Olibanums, 5 parts of the Radixs Astragali, 2 parts of Os Draconis, 5 parts of Flos Loniceraes, 2 parts of Cortex Phellodendris, 5 parts of Periostracum Cicadaes and Oleum sesami.
Embodiment 4:
Embodiment 1 prepares the Chinese medicine dropping for the treatment of otitis media in accordance with the following methods:
(1) Rhizoma Coptidis, Herba Menthae, Indigo Naturalis, Olibanum, the Radix Astragali, Os Draconis, Flos Lonicerae, Cortex Phellodendri and Periostracum Cicadae are immersed in Oleum sesami, airtight, seal, be statically placed in 42 hours, shady and cool lucifuge place up for safekeeping;
(2) said medicine is transferred in pot to slow fire heating 12 minutes;
(3) filtration residue adds Borneolum Syntheticum in filtrate, after it is dissolved, and the Chinese medicine dropping of the otitis media that can obtain medical treatment.
Embodiment 5:
Embodiment 2 prepares the Chinese medicine dropping for the treatment of otitis media in accordance with the following methods:
(1) Rhizoma Coptidis, Herba Menthae, Indigo Naturalis, Olibanum, the Radix Astragali, Os Draconis, Flos Lonicerae, Cortex Phellodendri and Periostracum Cicadae are immersed in Oleum sesami, airtight, seal, be statically placed in 36 hours, shady and cool lucifuge place up for safekeeping;
(2) said medicine is transferred in pot to slow fire heating 10 minutes;
(3) filtration residue adds Borneolum Syntheticum in filtrate, after it is dissolved, and the Chinese medicine dropping of the otitis media that can obtain medical treatment.
Embodiment 6:
Embodiment 3 prepares the Chinese medicine dropping for the treatment of otitis media in accordance with the following methods:
(1) Rhizoma Coptidis, Herba Menthae, Indigo Naturalis, Olibanum, the Radix Astragali, Os Draconis, Flos Lonicerae, Cortex Phellodendri and Periostracum Cicadae are immersed in Oleum sesami, airtight, seal, be statically placed in 48 hours, shady and cool lucifuge place up for safekeeping;
(2) said medicine is transferred in pot to slow fire heating 15 minutes;
(3) filtration residue adds Borneolum Syntheticum in filtrate, after it is dissolved, and the Chinese medicine dropping of the otitis media that can obtain medical treatment.

Claims (3)

1. treat the Chinese medicine dropping of otitis media for one kind, it is characterized in that, according to parts by weight meter, being prepared from by following raw material of Chinese medicine: 100~150 parts of 15~20 parts of Rhizoma Coptidis, 5~10 parts of Herba Menthaes, 5~10 parts of Borneolum Syntheticums, 6~8 parts of Indigo Naturaliss, 1~2 part of Olibanum, 3~5 parts of the Radixs Astragali, 1~2 part of Os Draconis, 3~5 parts of Flos Loniceraes, 1~2 part of Cortex Phellodendri, 3~5 parts of Periostracum Cicadaes and Oleum sesami.
2. a kind of Chinese medicine dropping for the treatment of otitis media according to claim 1, it is characterized in that, according to parts by weight meter, being prepared from by following raw material of Chinese medicine: 120 parts of 20 parts of Rhizoma Coptidis, 10 parts of Herba Menthaes, 8 parts of Borneolum Syntheticums, 6 parts of Indigo Naturaliss, 1 part of Olibanum, 3 parts of the Radixs Astragali, 1 part of Os Draconis, 3 parts of Flos Loniceraes, 2 parts of Cortex Phellodendris, 5 parts of Periostracum Cicadaes and Oleum sesami.
3. a preparation method for the Chinese medicine dropping for the treatment of otitis media claimed in claim 1, is characterized in that carrying out according to following steps:
(1) Rhizoma Coptidis, Herba Menthae, Indigo Naturalis, Olibanum, the Radix Astragali, Os Draconis, Flos Lonicerae, Cortex Phellodendri and Periostracum Cicadae are immersed in Oleum sesami, airtight, seal, be statically placed in 36~48 hours, shady and cool lucifuge place up for safekeeping;
(2) said medicine is transferred in pot to slow fire heating 10~15 minutes;
(3) filtration residue adds Borneolum Syntheticum in filtrate, after it is dissolved, and the Chinese medicine dropping of the otitis media that can obtain medical treatment.
CN201410235981.8A 2014-05-29 2014-05-29 A kind of Chinese medicine dropping treating otitis media and preparation method thereof Expired - Fee Related CN103989789B (en)

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Publication number Priority date Publication date Assignee Title
CN108938836A (en) * 2018-09-26 2018-12-07 河北地邦动物保健科技有限公司 A kind of Chinese medicine composition that treating dog otitis media suppurative, earplug agent and preparation method thereof

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