CN103984878A - 一种基于树搜索和片段组装的蛋白质结构预测方法 - Google Patents
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Cited By (15)
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CN104200131A (zh) * | 2014-07-23 | 2014-12-10 | 浙江工业大学 | 一种基于片段组装的蛋白质构象空间优化方法 |
CN104850361A (zh) * | 2015-06-01 | 2015-08-19 | 广东电网有限责任公司信息中心 | 一种数据清洗方法及系统 |
CN104933327A (zh) * | 2015-06-08 | 2015-09-23 | 浙江工业大学 | 一种局部增强的差分进化蛋白质构象空间搜索方法 |
CN104951669A (zh) * | 2015-06-08 | 2015-09-30 | 浙江工业大学 | 一种用于蛋白质结构预测的距离谱构建方法 |
CN104951670A (zh) * | 2015-06-08 | 2015-09-30 | 浙江工业大学 | 一种基于距离谱的群体构象空间优化方法 |
CN106372456A (zh) * | 2016-08-26 | 2017-02-01 | 浙江工业大学 | 一种基于深度学习Residue2vec的蛋白质结构预测方法 |
CN106650305A (zh) * | 2016-10-10 | 2017-05-10 | 浙江工业大学 | 一种基于局部抽象凸支撑面的多策略群体蛋白质结构预测方法 |
CN107145764A (zh) * | 2017-03-14 | 2017-09-08 | 浙江工业大学 | 一种双重分布估计引导的蛋白质构象空间搜索方法 |
CN109390033A (zh) * | 2018-08-29 | 2019-02-26 | 浙江工业大学 | 一种基于片段自适应选择的群体蛋白质结构预测方法 |
CN109461470A (zh) * | 2018-08-29 | 2019-03-12 | 浙江工业大学 | 一种蛋白质结构预测能量函数权重优化方法 |
WO2019134319A1 (zh) * | 2018-05-09 | 2019-07-11 | 深圳晶泰科技有限公司 | 类药有机分子的自动化构象分析方法 |
CN110164506A (zh) * | 2019-04-19 | 2019-08-23 | 浙江工业大学 | 一种基于域间残基接触的多域蛋白结构组装方法 |
WO2020029521A1 (zh) * | 2018-12-25 | 2020-02-13 | 深圳晶泰科技有限公司 | 有机分子的立体异构全集自动化生成方法 |
CN110890126A (zh) * | 2018-09-11 | 2020-03-17 | 富士通株式会社 | 用于探索化合物的设备和方法 |
CN112382336A (zh) * | 2020-12-01 | 2021-02-19 | 北京晶派科技有限公司 | 一种蛋白骨架设计方法及其应用 |
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Cited By (27)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104200131A (zh) * | 2014-07-23 | 2014-12-10 | 浙江工业大学 | 一种基于片段组装的蛋白质构象空间优化方法 |
CN104200131B (zh) * | 2014-07-23 | 2017-06-30 | 浙江工业大学 | 一种基于片段组装的蛋白质构象空间优化方法 |
CN104850361A (zh) * | 2015-06-01 | 2015-08-19 | 广东电网有限责任公司信息中心 | 一种数据清洗方法及系统 |
CN104933327B (zh) * | 2015-06-08 | 2018-06-01 | 浙江工业大学 | 一种局部增强的差分进化蛋白质构象空间搜索方法 |
CN104933327A (zh) * | 2015-06-08 | 2015-09-23 | 浙江工业大学 | 一种局部增强的差分进化蛋白质构象空间搜索方法 |
CN104951669A (zh) * | 2015-06-08 | 2015-09-30 | 浙江工业大学 | 一种用于蛋白质结构预测的距离谱构建方法 |
CN104951670A (zh) * | 2015-06-08 | 2015-09-30 | 浙江工业大学 | 一种基于距离谱的群体构象空间优化方法 |
CN104951670B (zh) * | 2015-06-08 | 2018-03-16 | 浙江工业大学 | 一种基于距离谱的群体构象空间优化方法 |
CN106372456A (zh) * | 2016-08-26 | 2017-02-01 | 浙江工业大学 | 一种基于深度学习Residue2vec的蛋白质结构预测方法 |
CN106372456B (zh) * | 2016-08-26 | 2019-01-22 | 浙江工业大学 | 一种基于深度学习的蛋白质结构预测方法 |
CN106650305A (zh) * | 2016-10-10 | 2017-05-10 | 浙江工业大学 | 一种基于局部抽象凸支撑面的多策略群体蛋白质结构预测方法 |
CN106650305B (zh) * | 2016-10-10 | 2019-01-22 | 浙江工业大学 | 一种基于局部抽象凸支撑面的多策略群体蛋白质结构预测方法 |
CN107145764B (zh) * | 2017-03-14 | 2019-07-30 | 浙江工业大学 | 一种双重分布估计引导的蛋白质构象空间搜索方法 |
CN107145764A (zh) * | 2017-03-14 | 2017-09-08 | 浙江工业大学 | 一种双重分布估计引导的蛋白质构象空间搜索方法 |
US11443834B2 (en) | 2018-05-09 | 2022-09-13 | Shenzhen Jingtai Technology Co., Ltd. | Automatic conformation analysis method for quasi-drug organic molecules |
WO2019134319A1 (zh) * | 2018-05-09 | 2019-07-11 | 深圳晶泰科技有限公司 | 类药有机分子的自动化构象分析方法 |
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CN109461470B (zh) * | 2018-08-29 | 2021-08-03 | 浙江工业大学 | 一种蛋白质结构预测能量函数权重优化方法 |
CN109390033A (zh) * | 2018-08-29 | 2019-02-26 | 浙江工业大学 | 一种基于片段自适应选择的群体蛋白质结构预测方法 |
CN110890126A (zh) * | 2018-09-11 | 2020-03-17 | 富士通株式会社 | 用于探索化合物的设备和方法 |
CN110890126B (zh) * | 2018-09-11 | 2024-03-26 | 富士通株式会社 | 用于探索化合物的设备和方法 |
WO2020029521A1 (zh) * | 2018-12-25 | 2020-02-13 | 深圳晶泰科技有限公司 | 有机分子的立体异构全集自动化生成方法 |
US11562809B2 (en) | 2018-12-25 | 2023-01-24 | Shenzhen Jingtai Technology Co., Ltd. | Method for automatically generating universal set of stereoisomers of organic molecule |
CN110164506A (zh) * | 2019-04-19 | 2019-08-23 | 浙江工业大学 | 一种基于域间残基接触的多域蛋白结构组装方法 |
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CN112382336B (zh) * | 2020-12-01 | 2023-09-01 | 北京晶泰科技有限公司 | 一种小蛋白骨架设计方法及其应用 |
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