CN103977432B - A kind of Color Sonography ultrasonic coupling agent - Google Patents
A kind of Color Sonography ultrasonic coupling agent Download PDFInfo
- Publication number
- CN103977432B CN103977432B CN201410110322.1A CN201410110322A CN103977432B CN 103977432 B CN103977432 B CN 103977432B CN 201410110322 A CN201410110322 A CN 201410110322A CN 103977432 B CN103977432 B CN 103977432B
- Authority
- CN
- China
- Prior art keywords
- grams
- parts
- herba
- coupling agent
- ultrasonic coupling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000007822 coupling agent Substances 0.000 title claims abstract description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 21
- 229920002472 Starch Polymers 0.000 claims abstract description 12
- 235000019698 starch Nutrition 0.000 claims abstract description 12
- 239000008107 starch Substances 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 10
- 239000008367 deionised water Substances 0.000 claims abstract description 7
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 7
- 230000001954 sterilising effect Effects 0.000 claims abstract description 7
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 6
- 241000746375 Andrographis Species 0.000 claims abstract description 6
- 241001163443 Daphne giraldii Species 0.000 claims abstract description 6
- 241000628997 Flos Species 0.000 claims abstract description 6
- 241000125142 Seseli Species 0.000 claims abstract description 6
- 239000002994 raw material Substances 0.000 claims abstract description 3
- 239000003814 drug Substances 0.000 claims description 11
- 239000008187 granular material Substances 0.000 claims description 10
- 238000002156 mixing Methods 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 6
- 238000004659 sterilization and disinfection Methods 0.000 claims description 5
- 239000000523 sample Substances 0.000 abstract description 5
- 206010040880 Skin irritation Diseases 0.000 abstract description 3
- 230000008878 coupling Effects 0.000 abstract description 3
- 238000010168 coupling process Methods 0.000 abstract description 3
- 238000005859 coupling reaction Methods 0.000 abstract description 3
- 230000036556 skin irritation Effects 0.000 abstract description 3
- 231100000475 skin irritation Toxicity 0.000 abstract description 3
- 229940126678 chinese medicines Drugs 0.000 abstract description 2
- 238000004140 cleaning Methods 0.000 abstract description 2
- 238000005516 engineering process Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 206010002198 Anaphylactic reaction Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000036783 anaphylactic response Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to the field of Chinese medicines, particularly to a kind of Color Sonography ultrasonic coupling agent.This Color Sonography ultrasonic coupling agent, it is characterized in that is made up of the raw material of following parts by weight: Herba Menthae 30 ~ 60 parts, Borneolum Syntheticum 20 ~ 40 parts, Flos Chrysanthemi 30 ~ 40 parts, Radix Angelicae Sinensis 20 ~ 50 parts, Herba Andrographis 30 ~ 50 parts, Herba Bidentis Tripartitae 20 ~ 60 parts, Rhizoma Donacis canniformis 30 ~ 50 parts, Herba Swertiae Mileensis 35 ~ 60 parts, Daphne giraldii Nitsche 20 ~ 40 parts, Cortex Phellodendri 30 ~ 40 parts, Rhizoma Belamcandae 20 ~ 30 parts, Radix Seselis mairei 10 ~ 15 parts, glycerol 50 ~ 80 parts, sterile deionized water 30 ~ 50 parts, starch 15 30 parts.The present invention has preferable coupling, without skin irritation, there is preferable sterilizing effect, do not damage probe, will not pollution clothes easy cleaning, and low cost, use the couplant of the present invention to carry out ultrasonic examination, image becomes apparent from.
Description
Technical field
Invention relates to the field of Chinese medicines, particularly to a kind of Color Sonography ultrasonic coupling agent.
Background technology
Color Sonography room unique dynamic display internal cardiac structures, heartthrob and the instrument of blood flowing, do not have any damage to human body.The function of ultrasonic coupling agent is to strengthen excusing from death probe and coupling between human body skin, the air between isolation ultrasonic probe and check point skin, makes sound wave conduction not affected by air, to reach good Detection results.
The most conventional couplant is mainly organogel composition, in semi-solid state, is coated onto on skin and easily produces discomfort sensation, it is also possible to produce the untoward reaction such as allergy, it is easy to get on patient's clothes, and be not easy to rinse, brings very burden to patient.
Summary of the invention
The present invention is in order to make up the deficiencies in the prior art, it is provided that a kind of without skin irritation, the Color Sonography excusing from death couplant that uses comfortable, low cost.
The present invention is achieved through the following technical solutions:
A kind of Color Sonography ultrasonic coupling agent, it is characterized in that is made up of the raw material of following parts by weight:
Herba Menthae 30 ~ 60 parts, Borneolum Syntheticum 20 ~ 40 parts, Flos Chrysanthemi 30 ~ 40 parts, Radix Angelicae Sinensis 20 ~ 50 parts, Herba Andrographis 30 ~ 50 parts, Herba Bidentis Tripartitae 20 ~ 60 parts, Rhizoma Donacis canniformis 30 ~ 50 parts, Herba Swertiae Mileensis 35 ~ 60 parts, Daphne giraldii Nitsche 20 ~ 40 parts, Cortex Phellodendri 30 ~ 40 parts, Rhizoma Belamcandae 20 ~ 30 parts, Radix Seselis mairei 10 ~ 15 parts, glycerol 50 ~ 80 parts, sterile deionized water 30 ~ 50 parts, starch 15-30 part.
The preparation method of the present invention is as follows: mixed by above-mentioned Chinese crude drug, and with Burdick lamp, it is carried out sterilization processing；It is then placed in baking box medicine is dried, with pulverizer, medicine is pulverized, be then ground into 200 mesh granules；Starch is joined in sterile deionized water and stir, be completely dissolved to starch and transparent gel, above-mentioned granule, clear gel and glycerol are mixed, utilize modern advanced pharmacy science and technology, make gel preparation.
Usage and dosage: external preparation, is applied in ultrasonic examination position by couplant, and heart is checked by mobile ultrasonic probe.
Pharmaceutical test: the present invention puts into container, adds suitable quantity of water, and stirring is completely dissolved to couplant, filters, thing residual solids material on filter paper after filtration, shows that couplant of the present invention has good water solublity, be dissolved completely in water.
Summary of Clinical Research data
Clinical observation:
Physical data:
As Color Sonography couplant, diagnosis and treatment patient 240 example is selected to carry out clinical observation.By random for patient subsidiary factory two groups, experimental group 120 example, matched group 12 example, basically identical in two groups of sons, without significant difference, there is comparability.
When carrying out Color Sonography, experimental group uses couplant of the present invention, and matched group uses conventional use of medical ultrasonic coupling agent, uses in strict accordance with operation instructions.
Using effect:
Experimental group: without anaphylaxis patient, image percent articulation reaches 98%.
Matched group: autopath 2 example, image percent articulation 90%.
Can be seen that the effect of couplant of the present invention is significantly better than matched group from result.
The invention has the beneficial effects as follows: there is preferable coupling, without skin irritation, there is preferable sterilizing effect, do not damage probe, will not pollution clothes easy cleaning, and low cost, use the couplant of the present invention to carry out ultrasonic examination, image becomes apparent from.
Detailed description of the invention
Embodiment 1:
By Herba Menthae 30 grams, Borneolum Syntheticum 20 grams, Flos Chrysanthemi 30 grams, Radix Angelicae Sinensis 20 grams, Herba Andrographis 30 grams, Herba Bidentis Tripartitae 30 grams, Rhizoma Donacis canniformis 35 grams, Herba Swertiae Mileensis 35 grams, Daphne giraldii Nitsche 20 grams, Cortex Phellodendri 30 grams, Rhizoma Belamcandae 20 grams, Radix Seselis mairei 10 grams mixing, and with Burdick lamp, it is carried out sterilization processing；It is then placed in baking box medicine is dried, with pulverizer, medicine is pulverized, be then ground into 200 mesh granules；20 grams of starch are joined in 30 grams of sterile deionized water and stir, be completely dissolved to starch and transparent gel, by above-mentioned granule, clear gel and 50 grams of glycerol mixing, utilize modern advanced pharmacy science and technology, make gel preparation and be the present invention.
Embodiment 2:
By Herba Menthae 40 grams, Borneolum Syntheticum 30 grams, Flos Chrysanthemi 35 grams, Radix Angelicae Sinensis 30 grams, Herba Andrographis 40 grams, Herba Bidentis Tripartitae 20 grams, Rhizoma Donacis canniformis 40 grams, Herba Swertiae Mileensis 45 grams, Daphne giraldii Nitsche 35 grams, Cortex Phellodendri 40 grams, Rhizoma Belamcandae 25 grams, Radix Seselis mairei 12 grams mixing, and with Burdick lamp, it is carried out sterilization processing；It is then placed in baking box medicine is dried, with pulverizer, medicine is pulverized, be then ground into 200 mesh granules；25 grams of starch are joined in 45 grams of sterile deionized water and stir, be completely dissolved to starch and transparent gel, by above-mentioned granule, clear gel and 70 grams of glycerol mixing, utilize modern advanced pharmacy science and technology, make gel preparation and be the present invention.
Embodiment 3:
By Herba Menthae 60 grams, Borneolum Syntheticum 35 grams, Flos Chrysanthemi 38 grams, Radix Angelicae Sinensis 45 grams, Herba Andrographis 45 grams, Herba Bidentis Tripartitae 50 grams, Rhizoma Donacis canniformis 45 grams, Herba Swertiae Mileensis 55 grams, Daphne giraldii Nitsche 40 grams, Cortex Phellodendri 40 grams, Rhizoma Belamcandae 30 grams, Radix Seselis mairei 15 grams mixing, and with Burdick lamp, it is carried out sterilization processing；It is then placed in baking box medicine is dried, with pulverizer, medicine is pulverized, be then ground into 200 mesh granules；30 grams of starch are joined in 50 grams of sterile deionized water and stir, be completely dissolved to starch and transparent gel, by above-mentioned granule, clear gel and 80 grams of glycerol mixing, utilize modern advanced pharmacy science and technology, make gel preparation and be the present invention.
Claims (1)
1. a Color Sonography ultrasonic coupling agent, it is characterised in that: it is made up of following raw material: by Herba Menthae 30 grams, Borneolum Syntheticum 20 grams, Flos Chrysanthemi 30 grams, Radix Angelicae Sinensis 20 grams, Herba Andrographis 30 grams, Herba Bidentis Tripartitae 30 grams, Rhizoma Donacis canniformis 35 grams, Herba Swertiae Mileensis 35 grams, Daphne giraldii Nitsche 20 grams, Cortex Phellodendri 30 grams, Rhizoma Belamcandae 20 grams, Radix Seselis mairei 10 grams mixing, and with Burdick lamp, it is carried out sterilization processing；It is then placed in baking box medicine is dried, with pulverizer, medicine is pulverized, be then ground into 200 mesh granules；20 grams of starch are joined in 30 grams of sterile deionized water and stir, be completely dissolved to starch and transparent gel, by above-mentioned granule, clear gel and 50 grams of glycerol mixing, make gel preparation and be Color Sonography ultrasonic coupling agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410110322.1A CN103977432B (en) | 2014-03-24 | 2014-03-24 | A kind of Color Sonography ultrasonic coupling agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410110322.1A CN103977432B (en) | 2014-03-24 | 2014-03-24 | A kind of Color Sonography ultrasonic coupling agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103977432A CN103977432A (en) | 2014-08-13 |
| CN103977432B true CN103977432B (en) | 2016-08-17 |
Family
ID=51269751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410110322.1A Active CN103977432B (en) | 2014-03-24 | 2014-03-24 | A kind of Color Sonography ultrasonic coupling agent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103977432B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104758958A (en) * | 2015-04-24 | 2015-07-08 | 刘传文 | Medicine assisting in ultrasonic diagnosis of an ovarian cyst and preparation method thereof |
| CN104922703A (en) * | 2015-06-26 | 2015-09-23 | 荆丙艳 | Medical bactericidal antiallergic ultrasonic coupling agent |
| CN106421824A (en) * | 2016-10-24 | 2017-02-22 | 广州穗健医疗科技有限公司 | Biological coupling slices of ultrasonic therapy instrument and preparation method thereof |
| CN107158412A (en) * | 2017-04-28 | 2017-09-15 | 四川康源医疗设备有限公司 | B ultrasound couplant and preparation method thereof |
| CN112107616B (en) * | 2020-09-14 | 2021-12-10 | 泸州市中医医院(泸州市中西医结合医院、泸州市江阳区中医医院) | Traditional Chinese medicine preparation for magnetic resonance MRCP examination and preparation method thereof |
| CN113907095B (en) * | 2021-10-13 | 2023-04-14 | 宁夏农林科学院植物保护研究所（宁夏植物病虫害防治重点实验室） | Application of divaricate saposhnikovia root in biological control, biological control medicament and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101658680A (en) * | 2009-10-09 | 2010-03-03 | 李晓鲁 | Medical environment-friendly sterilization ultrasound coupling agent and preparation method thereof |
| CN102028961A (en) * | 2010-12-04 | 2011-04-27 | 蔡永军 | Ultrasonic coupling agent used by traumatic patient after surgery |
| CN103341184A (en) * | 2013-07-31 | 2013-10-09 | 王玉梅 | Ultrasonic coupling agent and preparation method thereof |
| CN103638535A (en) * | 2013-12-04 | 2014-03-19 | 夏青 | B ultrasound coupling agent containing traditional Chinese components |
-
2014
- 2014-03-24 CN CN201410110322.1A patent/CN103977432B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101658680A (en) * | 2009-10-09 | 2010-03-03 | 李晓鲁 | Medical environment-friendly sterilization ultrasound coupling agent and preparation method thereof |
| CN102028961A (en) * | 2010-12-04 | 2011-04-27 | 蔡永军 | Ultrasonic coupling agent used by traumatic patient after surgery |
| CN103341184A (en) * | 2013-07-31 | 2013-10-09 | 王玉梅 | Ultrasonic coupling agent and preparation method thereof |
| CN103638535A (en) * | 2013-12-04 | 2014-03-19 | 夏青 | B ultrasound coupling agent containing traditional Chinese components |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103977432A (en) | 2014-08-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103977432B (en) | A kind of Color Sonography ultrasonic coupling agent | |
| CN101214286B (en) | Chinese medicine white spirit preparations for effectively treating rheumatic pain diseases | |
| CN102552361A (en) | Externally applied medicinal liquor and preparation method thereof | |
| CN103494932B (en) | Houttuynia cordata scalding spray film agent and preparation method thereof | |
| CN103285355B (en) | Medicine for treating calculi in urinary system | |
| CN102697925A (en) | Traditional Chinese medicine combination for treating aural eczema | |
| CN102698166A (en) | Chinese medicinal composition for treating human skin itch | |
| CN102125612B (en) | Chinese medicinal preparation for treating acute lumbar sprain | |
| CN104510972A (en) | Traditional Chinese medicinal composition for treating asthma and preparation method of traditional Chinese medicinal composition | |
| CN104013901A (en) | Medicament for treating pelvic inflammation | |
| CN102512535B (en) | Traditional Chinese medicine wiping solution for treating infant dermatitis caused by diaper | |
| CN103330810A (en) | Emergency medicine for snake wounds | |
| CN103566187A (en) | Paste for eliminating sores and promoting tissue regeneration | |
| CN108371688A (en) | A kind of graphene analgesic patch and preparation method thereof | |
| CN101732425A (en) | Externally-applied medicine composite for psoriasis | |
| CN104740038B (en) | One kind treats prostatitic Chinese medicine | |
| CN106729011A (en) | A kind of topical composition | |
| CN101342285A (en) | Chinese medicinal composition for treating exterior trauma and preparation method thereof | |
| CN103083639B (en) | Medicament for treating postpartum pain of body | |
| CN102961727B (en) | Traditional Chinese medicine composition for treating bone diseases in clinical nursing | |
| CN102846669B (en) | Medicament for treating aphtha | |
| CN103656086B (en) | The Chinese medicine preparation for the treatment of urarthritis | |
| CN103191202A (en) | Externally applied Chinese herb medicinal liquor for treating scapulohumeral periomethritis and arthralgia of limbs | |
| CN202161684U (en) | Heart meridian tissue disease treatment apparatus | |
| CN103751235A (en) | Traditional Chinese medicine composition for treating dysentery |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20191126 Address after: 251600 government residence of jade emperor temple town, Shanghe County, Ji'nan City, Shandong Province Patentee after: JINAN HUAQING AGRICULTURAL MACHINERY TECHNOLOGY Co.,Ltd. Address before: 250101, room 9, building 4569, dragon garden, 1801 Fenghuang Road, Ji'nan hi tech Zone, Shandong, China Patentee before: JINAN WEICHUAN INFORMATION TECHNOLOGY Co.,Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20200422 Address after: 250000 Hanyu Jingu A2-4-2003, Jinan High-tech Zone, Shandong Province Patentee after: SHANDONG HAINUO INTELLECTUAL PROPERTY OPERATION MANAGEMENT Co.,Ltd. Address before: 251600 government residence of jade emperor temple town, Shanghe County, Ji'nan City, Shandong Province Patentee before: JINAN HUAQING AGRICULTURAL MACHINERY TECHNOLOGY Co.,Ltd. |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20201030 Address after: Room 102, floor 1, North Market Supervision Bureau, Nanding Dang Road, Jiahe neighborhood committee, Wenting street, Chengwu County, Heze City, Shandong Province Patentee after: Chengwu Yichang Information Technology Co.,Ltd. Address before: 250000 Hanyu Jingu A2-4-2003, Jinan High-tech Zone, Shandong Province Patentee before: SHANDONG HAINUO INTELLECTUAL PROPERTY OPERATION MANAGEMENT Co.,Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20221213 Address after: No.20, No.001, Bole Street, Chengwu County, Heze City, Shandong Province, 274000 Patentee after: Chengwu Qiyuan State owned Assets Operation Co.,Ltd. Address before: 274200 Room 102, 1 / F, Jiahe neighborhood committee, Wenting street, Chengwu County, Heze City, Shandong Province Patentee before: Chengwu Yichang Information Technology Co.,Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20231128 Address after: No. 678 Chenggucheng Street, Chengwu County, Heze City, Shandong Province, 274200 Patentee after: Chengwu Dadi Corn Development Co.,Ltd. Address before: No.20, No.001, Bole Street, Chengwu County, Heze City, Shandong Province, 274000 Patentee before: Chengwu Qiyuan State owned Assets Operation Co.,Ltd. |
|
| TR01 | Transfer of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A type of ultrasound coupling agent for cardiac ultrasound Effective date of registration: 20231215 Granted publication date: 20160817 Pledgee: Industrial and Commercial Bank of China Limited Chengwu sub branch Pledgor: Chengwu Dadi Corn Development Co.,Ltd. Registration number: Y2023980072102 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right |