CN103976708B - Corneal vertex alignment methods and system and axis oculi optical path length measuring method and system - Google Patents
Corneal vertex alignment methods and system and axis oculi optical path length measuring method and system Download PDFInfo
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Abstract
The invention discloses the method that corneal vertex is directed at, comprise the steps: to judge that corneal vertex is in the perpendicular at eye optical system primary optical axis place and judges that corneal vertex is in the horizontal plane at eye optical system primary optical axis place according to horizontal direction corneal position alignment modules according to vertical direction corneal position alignment modules, determine that corneal vertex is on eye optical system primary optical axis；Judge that corneal vertex is in the front or behind of the operating position that described eye optical system is arranged according to described vertical direction corneal position alignment modules or described horizontal direction corneal position alignment modules；Described corneal vertex is moved to described operating position.The present invention also disclosed the system of corneal vertex alignment and the method apply to OCT system and the measuring method of axis oculi optical path length that axis oculi optical path length is measured.Present invention achieves the accurate alignment of corneal vertex, and realize the accurate measurement of axis oculi optical path length on this basis.
Description
Technical field
The invention belongs to ophthalmology OCT field, be specifically related to a kind of method that corneal vertex is accurately directed at, be
Unite and the method and system are applied to axis oculi optical path length and measure and ophthalmic medical equipment.
Background technology
Optical coherent chromatographic imaging (OCT, Optical Coherence Tomography) is a kind of emerging
Optical image technology, for traditional clinical imaging means, have resolution height, image taking speed,
The advantages such as radiationless damage, moderate cost, compact conformation, are basic medical research and clinical diagnostic applications
Important potential instrument.Currently, in multiple optical Ophthalmologic apparatus, for ophthalmologic examination and controlling
The OCT device treated has become as the Ophthalmologic apparatus that eye disease diagnosis is indispensable.
In a lot of ophthalmic medical instruments, it is required for allowing instrument light path primary optical axis be directed at human eye pupil or cornea
Summit.In existing instrument, many employing iris identification are directed at pupil.But due to the difference of different people eye-shaped state,
After pupil center's alignment, corneal vertex may not be directed at system light path primary optical axis.Reason has 2 points: one, people
There is certain angle in eye axle and the optical axis, and the corner dimension of different human eye is different.Practical operation instrument mistake
Cheng Zhong, people to be measured stares at a certain fixation point, but this fixation point is not used to accurately judge human eye optical axis and regard
The angle of axle.Even if thus pupil optical system for alignment primary optical axis, but corneal vertex is not the most at system light path key light
On axle；Two, according to iris identification pupil center, after allowing system light path primary optical axis be directed at pupil center, by
In the difference of human eye's anterior chamber form, now corneal vertex may not be directed at system light path primary optical axis.
According to the measuring method of optics, to accurately measure corneal parameters, such as corneal curvature and thickness etc., need
The corneal surface shape image gathered is carried out image rectification, and whether corneal vertex is in system light path primary optical axis
The image rectification after the three-dimensional imaging of the accuracy of correction, especially cornea can be affected.Thus measure people to be measured
During cornea cross-section image, corneal summit is needed accurately to be directed at.And tester is according to iris imaging side
The corneal vertex of detected person can only substantially be regulated to system primary optical axis by method, it is impossible to realizes corneal vertex
Accurately it is adjusted to the purpose of system primary optical axis.Owing to corneal vertex cannot accurately adjust the primary optical axis to system,
Thus the test result that result in the series of parameters relevant with eyes such as people's axis oculi optical path length is inaccurate.
Summary of the invention
The present invention provides a kind of corneal vertex alignment methods and system, also provides and this corneal vertex is directed at system
System is used in the OCT system surveying people's axis oculi optical path length, additionally provides the method fortune this corneal vertex being directed at
It is used in the method surveyed on people's axis oculi optical path length, its object is to solve following defect: (1), corneal vertex
Cannot accurately be directed at；(2) the axis oculi optical path length, caused because corneal vertex cannot accurately be directed at is measured
Inaccurate.
Technical scheme:
The method of a kind of corneal vertex alignment, comprises the steps:
First reception of the vertical direction optical system for alignment detector according to vertical direction corneal position alignment modules
On the image that face receives, the first hot spot of display is on the vertical centrage of described first receiving plane, determines
Described corneal vertex is on the perpendicular at eye optical system primary optical axis place；According to horizontal direction cornea
Display on the image that second receiving plane of the horizontal direction optical system for alignment detector of position alignment module receives
Second hot spot is on the horizontal center line of described second receiving plane, determines that described corneal vertex is in described eye
On the horizontal plane at section's optical system primary optical axis place；It is in described perpendicular and described according to corneal vertex
Horizontal plane, determines that described corneal vertex is on described eye optical system primary optical axis；
According to described vertical direction corneal position alignment modules or described horizontal direction corneal position alignment modules
Judge that corneal vertex is in the front or behind of the operating position that described eye optical system is arranged；
Described corneal vertex is moved to described operating position by control system；
Wherein, what described operating position referred to described vertical direction corneal position alignment modules goes out light light path key light
The first joint that axle and light-receiving optical path primary optical axis cross or described horizontal direction corneal position alignment modules
Go out light light path primary optical axis and the second joint that light-receiving optical path primary optical axis crosses；The primary optical axis of described ophthalmic system
For described vertical direction corneal position alignment modules and the intersecting lens of described horizontal direction corneal position alignment modules.
Further: described according to vertical direction corneal position alignment modules judge corneal vertex be in ophthalmology light
Cornea is judged on the perpendicular at system primary optical axis place and according to horizontal direction corneal position alignment modules
Summit is on the horizontal plane at eye optical system primary optical axis place, determines that corneal vertex is in opticianry
Concretely comprising the following steps on system primary optical axis:
Described vertical direction corneal position alignment modules and described horizontal direction corneal position alignment modules are set；
Described vertical direction corneal position alignment modules includes that being arranged on it goes out the vertical direction pair on light light path primary optical axis
Quasi-optical source, vertical direction collecting lens, vertical direction go out light diaphragm, vertical direction pinhole plate and vertical direction
Luminous lens and the vertical direction being arranged on its light-receiving optical path primary optical axis receive lens and vertical direction alignment
Light path detector；Described horizontal direction corneal position alignment modules includes that being arranged on it goes out light light path primary optical axis
Horizontal direction alignment light source, horizontal direction collecting lens, horizontal direction go out light diaphragm, horizontal direction pinhole plate
The horizontal direction reception lens with horizontal direction luminous lens and being arranged on its light-receiving optical path primary optical axis and level
Direction optical system for alignment detector；
The primary optical axis going out light light path of described vertical direction corneal position alignment modules and the primary optical axis of light-receiving optical path
Constitute described perpendicular；The primary optical axis going out light light path of described horizontal direction corneal position alignment modules and being subject to
The primary optical axis of light light path constitutes described horizontal plane；Described first joint and the second joint are in described
On the primary optical axis of eye optical system；
It is in the perpendicular at described eye optical system primary optical axis place according to described corneal vertex and is in institute
The horizontal plane stating eye optical system primary optical axis place judges that corneal vertex is in eye optical system primary optical axis
On.
Further: be in the most flat of described eye optical system primary optical axis place according to described corneal vertex
Mask body decision method is: receive according to the first receiving plane of described vertical direction optical system for alignment detector
On image, the first hot spot of display is on the vertical centrage of optical system for alignment detector and judges described corneal vertex
It is in the perpendicular at described eye optical system primary optical axis place；
The horizontal plane being in described eye optical system primary optical axis place according to described corneal vertex specifically judges
Method is: according to display on the image that the second receiving plane of described horizontal direction optical system for alignment detector obtains
Second hot spot is on the horizontal center line of optical system for alignment detector and judges that described corneal vertex is in described ophthalmology
The horizontal plane at optical system primary optical axis place.
Further: described first joint and described second joint overlap.
Further: according to described vertical direction corneal position alignment modules or described horizontal direction cornea position
Put alignment modules judge corneal vertex be in described eye optical system arrange operating position front or after
The concrete grammar of side is: described first hot spot is in the vertical center of described vertical direction optical system for alignment detector
The first half of line and the center of deviation vertical direction optical system for alignment detector are the most remote, then described corneal vertex is described
It is positioned at rear, operating position and deviation is the most remote；Described first hot spot is in the detection of described vertical direction optical system for alignment
The lower half of the vertical centrage of device and the center of deviation vertical direction optical system for alignment detector are the most remote, then illustrate
Described corneal vertex is positioned at front, operating position and deviation is the most remote；
Described second hot spot be in the horizontal center line of described horizontal direction optical system for alignment detector left side and
The center deviateing described horizontal direction optical system for alignment detector is the most remote, then illustrate that described corneal vertex is positioned at described
Front, operating position and deviation are the most remote；Described second hot spot is in described horizontal direction optical system for alignment detector
The right-hand part of horizontal center line and the center of deviation horizontal direction optical system for alignment detector are the most remote, then explanation is described
Corneal vertex is positioned at rear, operating position and deviation is the most remote；
Wherein, described corneal vertex is positioned at front, described operating position and refers to corneal vertex from horizontal direction angle
Too far, human eye need to be to horizontal direction cornea for film location alignment modules or vertical direction corneal position alignment modules
Position alignment module or vertical direction corneal position alignment modules are near corneal vertex could move to described work
Make position；Described corneal vertex is positioned at rear, operating position and refers to corneal vertex from horizontal direction corneal position
Alignment modules or vertical direction corneal position alignment modules are the nearest, and human eye need to be away from horizontal direction corneal position
Corneal vertex could be moved to operating position by alignment modules or vertical direction corneal position alignment modules.
Further, in step: judge that corneal vertex is in eye according to vertical direction corneal position alignment modules
Judge on the perpendicular at section's optical system primary optical axis place and according to horizontal direction corneal position alignment modules
Corneal vertex is on the horizontal plane at eye optical system primary optical axis place, determines that corneal vertex is in ophthalmology
Before on optical system primary optical axis, also comprise the steps:
Regulate pupil center location according to iris imaging system, pupil center location is substantially adjusted to opticianry
On system primary optical axis；
Iris picture is adjusted to more visible level, now judges that described corneal vertex is in described eye optical system
Near the operating position arranged.
Further: described iris picture is adjusted to more visible level is that the position by regulation sample arm assembly is real
Existing, its concrete regulating step is:
Around controlling described regulation sample arm assembly by artificial or control system and move up and down,
Described corneal vertex is moved near the operating position that described system is arranged.
The present invention also disclosed the system of a kind of corneal vertex alignment, including: vertical direction corneal position is directed at
Module, horizontal direction corneal position alignment modules；Described vertical direction corneal position alignment modules is used for judging
Corneal vertex is on the perpendicular at eye optical system primary optical axis place；Described horizontal direction corneal position
Alignment modules is for judging that corneal vertex is in the horizontal plane at eye optical system primary optical axis place；According to
Described vertical direction corneal position alignment modules and described horizontal direction corneal position alignment modules judge angle jointly
Film summit is on system primary optical axis.
Further: described vertical direction corneal position alignment modules includes: be arranged on out light light path primary optical axis
On vertical direction alignment light source, vertical direction collecting lens, vertical direction go out light diaphragm, vertical direction pin
Orifice plate and vertical direction luminous lens and the vertical direction being arranged on light-receiving optical path primary optical axis receive lens and
Vertical direction optical system for alignment detector；Described horizontal direction corneal position alignment modules includes being arranged on out light light
The horizontal direction alignment light source of road primary optical axis, horizontal direction collecting lens, horizontal direction go out light diaphragm, level
Pointing needle orifice plate and horizontal direction luminous lens and be arranged on the horizontal direction of light-receiving optical path primary optical axis and receive thoroughly
Mirror and horizontal direction optical system for alignment detector；Described first joint and described second joint are in described
On the primary optical axis of eye optical system.
Further: it is saturating that described vertical direction corneal position alignment modules also includes being arranged on described vertical reception
The vertical optical filter of mirror front end；Described horizontal direction corneal position alignment modules also includes being arranged on described level
Receive the horizontal optical filter of lens front.
The present invention also disclosed a kind of OCT system surveying people's axis oculi optical path length, including: OCT system source,
Fiber coupler, detection system, control system, sample arm assembly and reference arm assembly；Described OCT system
Light source provides incident illumination to described sample arm assembly and described reference arm assembly respectively through fiber coupler, wherein
Through the incident light beam strikes of described sample arm assembly to human eye optical fundus and through human eye fundus reflex, reflect
Light after described sample arm assembly with the light reflected from described reference arm assembly at described fiber coupler
In interfere, described interference light is detected system and detects, through control system process after, obtain human eye
OCT fault imaging, it is characterised in that: described sample arm assembly includes that the corneal vertex alignment being arranged on end is
System, described corneal vertex includes described vertical direction corneal position alignment modules and described level side to Barebone
To corneal position alignment modules.
Further, described sample arm assembly is additionally included in and sets gradually in light path: Polarization Controller, tune
Light path module, X-direction scanning means, Y-direction scanning means and diopter regulate mirror and connect mesh object lens；Wherein,
Described Polarization Controller and described fiber coupler are adjacent.
The present invention also disclosed a kind of method surveying people's axis oculi optical path length light path value, it is characterised in that includes
Following steps:
Described corneal vertex alignment methods is utilized corneal vertex to be accurately registered on the primary optical axis of OCT system,
And make described corneal vertex be in the operating position that system is arranged；
According to formula LEye=LRDK1toEc+S+hRetinal, record people axis oculi optical length LEye；
Wherein: what described operating position referred to described vertical direction corneal position alignment modules goes out light light path key light
The first joint that axle and light-receiving optical path primary optical axis cross or described horizontal direction corneal position alignment modules
Go out light light path primary optical axis and the second joint that light-receiving optical path primary optical axis crosses；
LRDK1toEc represents when the light modulation journey assembly of OCT system is in reset position, OCT system scanning imagery
The distance of locus corresponding to the top of image and the corneal vertex being in operating position；S is light modulation journey group
The displacement of part；HRetinal is that the locus corresponding to retina OCT image top is yellow to measured
The light path of speckle central fovea, this value is obtained by oculi posterior segment OCT image.
Beneficial effects of the present invention: (1), utilize vertical direction corneal position alignment modules and horizontal direction angle
Corneal vertex is adjusted the operating position arranged to system by film location alignment modules accurately, thus reaches angle
The purpose that film summit is accurately directed at；(2), Barebone is applied to survey the OCT of people's axis oculi optical length by cornea
In system, OCT system can be realized and accurately measure the purpose of people's axis oculi optical path length；(3) by cornea alignment side
Method is used in the measuring method of axis oculi optical path length, it is achieved that the accurate measurement of axis oculi light path value.
Accompanying drawing explanation
Fig. 1 is the schematic flow sheet of corneal vertex alignment methods；
Fig. 2 is the OCT system light path surveying people's axis oculi optical path length including corneal vertex to Barebone 500
Figure；
Fig. 3 is vertical direction corneal position alignment modules 200 index path；
Fig. 4 is horizontal direction corneal position alignment modules 300 index path；
Fig. 5 is the corneal vertex that the first receiving plane 208a of vertical direction optical system for alignment detector 208 obtains
The schematic diagram of the perpendicular at Ec deviation eye optical system primary optical axis place；
Fig. 6 is the corneal vertex that the first receiving plane 208a of vertical direction optical system for alignment detector 208 obtains
Ec is in the schematic diagram of the perpendicular at eye optical system primary optical axis place；
Fig. 7 is the corneal vertex that the second receiving plane 308a of horizontal direction optical system for alignment detector 308 obtains
The schematic diagram of the horizontal plane at Ec deviation eye optical system primary optical axis place；
Fig. 8 is the corneal vertex that the second receiving plane 308a of horizontal direction optical system for alignment detector 308 obtains
Ec is in the schematic diagram of the horizontal plane at eye optical system primary optical axis place；
Fig. 9 is that axis oculi optical path length calculates schematic diagram.
In figure, the title of each sequence number and correspondence is respectively as follows:
E, sample (human eye)
Ec, corneal vertex
101, OCT system source
102, fiber coupler
103, Polarization Controller
1050, reference arm assembly
104, reference arm light Reuter mirror
105, reference arm reflecting mirror
106, detection system
107, control system
108, sample arm light path focusing lens
1080, light modulation journey module
109, X-direction light path scanning means
110, Y-direction light path scanning means
111, diopter regulation mirror
112, mesh object lens are connect
500, corneal vertex is to Barebone
200, vertical direction corneal position alignment modules
201, vertical direction alignment light source
202, vertical direction collecting lens
203, vertical direction goes out light diaphragm
204, vertical direction pinhole plate
205, vertical direction luminous lens
206, vertical direction optical filter
207, vertical direction receives lens
208, vertical direction optical system for alignment detector
208a, the first receiving plane of vertical direction optical system for alignment detector 208
300, horizontal direction corneal position alignment modules
301, horizontal direction alignment light source
302, horizontal direction collecting lens
303, horizontal direction goes out light diaphragm
304, horizontal direction pinhole plate
305, horizontal direction luminous lens
306, horizontal direction optical filter
307, horizontal direction receives lens
308, horizontal direction optical system for alignment detector
308a, the second receiving plane of horizontal direction optical system for alignment detector 308
400, sample arm assembly
Detailed description of the invention
In order to make the technical problem to be solved, technical scheme and beneficial effect clearer,
Below in conjunction with drawings and Examples, the present invention is further elaborated.Should be appreciated that this place is retouched
The specific embodiment stated only in order to explain the present invention, is not intended to limit the present invention.
(1), corneal vertex alignment methods
With reference to the schematic flow sheet that Fig. 1, Fig. 1 are cornea alignment methods, comprise the steps:
S101: judge that corneal vertex is in eye optical system master according to vertical direction corneal position alignment modules
The perpendicular at optical axis place and judge that corneal vertex is in eye according to horizontal direction corneal position alignment modules
The horizontal plane at section's optical system primary optical axis place, determines that corneal vertex is on eye optical system primary optical axis；
S102: according to described vertical direction corneal position alignment modules or described horizontal direction corneal position pair
Quasi-mode block judges that corneal vertex is in the front or behind of the operating position that eye optical system is arranged；
Described corneal vertex is moved to described operating position by S103: control system.
Specifically, for step S101, with reference to Fig. 2, vertical direction corneal position alignment modules 200 judges
Whether corneal vertex Ec is on the perpendicular at eye optical system primary optical axis place, horizontal direction cornea position
Put alignment modules 300 and can only judge whether corneal vertex Ec is in the level at eye optical system primary optical axis place
In plane.Because knowing from light path principle, it is impossible to only judge from vertical direction corneal position alignment modules 200
Whether corneal vertex Ec is on eye optical system primary optical axis, simultaneously also cannot be only from horizontal direction cornea
Position alignment module 300 judges whether corneal vertex Ec is on eye optical system primary optical axis；Therefore only have
When the satisfied perpendicular being both in eye optical system primary optical axis place of corneal vertex Ec, it is in again ophthalmology light
On the horizontal plane at system primary optical axis place, just can determine that corneal vertex is in eye optical system primary optical axis
On.In the present invention, vertical direction corneal position alignment modules 200 go out light light path primary optical axis and light light
Road primary optical axis intersects at the first joint and constitutes perpendicular；Horizontal direction corneal position alignment modules 300
Go out light light path primary optical axis and light-receiving optical path primary optical axis intersects at the second joint and constitutes horizontal plane.
Illustrate that vertical direction corneal position alignment modules 200 and horizontal direction corneal position are to quasi-mode in detail below
The composition of block 300.
Fig. 3 is vertical direction corneal position alignment modules 200 index path.It is arranged on vertical direction corneal position
The light that the vertical direction alignment light source 201 gone out on light light path primary optical axis of alignment modules 200 sends is through vertically side
After collecting lens 202, vertical direction go out light diaphragm 203, focus on vertical direction pinhole plate 204, this light
Cornea top is focused on after being then passed through vertical direction luminous lens 205 behind the hole of vertical direction pinhole plate 204
Point Ec, after corneal vertex Ec reflects, light beam is through being arranged on vertical direction corneal position alignment modules 200
Light-receiving optical path primary optical axis on vertical direction receive lens 207, converge to vertical direction optical system for alignment detector
On 208.Go out light light path primary optical axis and the light-receiving optical path primary optical axis of vertical direction corneal position alignment modules 200 are handed over
It is compiled in the first joint A1.
Further, also set up on light light path primary optical axis in going out of vertical direction corneal position alignment modules 200
Having vertical direction optical filter 206, it receives between lens 207 at the first joint A1 and vertical direction,
Namely receive at vertical direction at the incidence end of lens 207.The effect of vertical direction optical filter 206 is
Other veiling glares beyond vertical direction alignment light source 201 are filtered, only by vertical direction to quasi-optical for crossing
The light that source 201 sends.
Further, vertical direction optical system for alignment detector 208 at least position sensor dough-making powder battle array detection battle array
One in row, certainly, for the optical system for alignment detector of other satisfied use conditions, also protects in the present invention
The row protected.
Fig. 4 is the index path of horizontal direction corneal position alignment modules 300.It is arranged on horizontal direction cornea position
Put light that the horizontal direction alignment light source 301 on light light path primary optical axis of alignment modules 300 sends through level
After direction collecting lens 302, horizontal direction go out light diaphragm 303, focus on horizontal direction pinhole plate 304, should
Light through horizontal direction pinhole plate 304 hole portion after be then passed through horizontal direction luminous lens 305 after focus on angle
Film summit Ec.After corneal vertex Ec reflects, the configured corneal position alignment modules in the horizontal direction of light beam
Horizontal direction on the light-receiving optical path primary optical axis of 300 receives lens 307, converges to horizontal direction optical system for alignment and visits
Survey on device 308.Go out light light path primary optical axis and light-receiving optical path primary optical axis is intersected in the second joint A2.
Further, the also setting up on light light path primary optical axis going out of horizontal direction corneal position alignment modules 300
Having horizontal direction optical filter 306, it receives between lens 307 at the second joint A2 and horizontal direction,
Receive the most in the horizontal direction at the incidence end of lens 307, be used for filtering horizontal direction alignment light source 301
Other veiling glares, the light only sent by horizontal direction alignment light source 301.
Further, horizontal direction optical system for alignment detector 308 at least position sensor, face battle array detection battle array
One in row.Certainly, for the optical system for alignment detector of other satisfied use conditions, also protect in the present invention
The row protected.
Further, the first joint A1 and the second joint A2 is arranged to coincidence.
In the present invention, horizontal direction corneal position alignment modules 300 go out light light path primary optical axis and light light
Road primary optical axis constitutes described horizontal plane, and the definition of this horizontal plane is applicable in full；Vertical direction cornea position
That puts alignment modules 200 goes out light light path primary optical axis and light-receiving optical path primary optical axis composition perpendicular, and this is vertically put down
The definition in face is applicable in full.
With reference to Fig. 5 and Fig. 6.Fig. 5 is the first receiving plane 208a of vertical direction optical system for alignment detector 208
The schematic diagram of the perpendicular at the corneal vertex Ec deviation eye optical system primary optical axis place obtained.In Fig. 5,
L208a is the vertical centrage of the first receiving plane 208a of vertical direction optical system for alignment detector 208, L208b
Horizontal center line for the first receiving plane 208a of vertical direction optical system for alignment detector 208.In Figure 5,
First hot spot 204a is not on L208a, represents that corneal vertex Ec deviate from eye optical system master
The perpendicular at optical axis place.In figure 6, the first hot spot 204a is on L208a, can judge accordingly
Corneal vertex Ec is in the perpendicular at eye optical system primary optical axis place.But, according to Fig. 5 and Fig. 6
Can only judge whether corneal vertex Ec is in the perpendicular at eye optical system primary optical axis place, but whether locate
Cannot individually judge on eye optical system primary optical axis.Further, with reference to Fig. 3, Fig. 5 and Fig. 6, perpendicular
Nogata is to the center o208 of the first receiving plane 208a of optical system for alignment detector 208 and the first joint A1 phase
Lens 207 are received for vertical direction be conjugated, the first joint A1 and vertical direction pinhole plate 204 relative to
Vertical direction luminous lens 205 is conjugated.
With reference to Fig. 7 and Fig. 8.Fig. 7 is the second receiving plane 308a of horizontal direction optical system for alignment detector 308
The schematic diagram of the horizontal plane at the corneal vertex Ec deviation eye optical system primary optical axis place obtained.In Fig. 7,
L308a is the vertical centrage of the second receiving plane 308a of horizontal direction optical system for alignment detector 308, L308b
The second receiving plane 308a horizontal center line for horizontal direction optical system for alignment detector 308.Second light in Fig. 7
Speckle 304a is not on L308b, represents corneal vertex Ec deviation eye optical system primary optical axis place
Horizontal plane.In fig. 8, the second hot spot 304a is on L308b, therefore can judge corneal vertex
Ec is in the horizontal plane at eye optical system primary optical axis place.Further, with reference to Fig. 4, Fig. 7 and Fig. 8,
The center o308 and the second joint A2 of the second receiving plane 308a of horizontal direction optical system for alignment detector 308
Receiving lens 307 relative to horizontal direction to be conjugated, the second joint A2 is relative with horizontal direction pinhole plate 204
It is conjugated in horizontal direction luminous lens 305.Can only judge whether corneal vertex is in eye according to Fig. 7 and Fig. 8
The horizontal plane at section's optical system primary optical axis place, but whether be on eye optical system primary optical axis and then cannot
Individually judge.
In sum, corneal vertex Ec cannot be judged whether according to vertical direction corneal position alignment modules 200
It is on the primary optical axis at eye optical system place, also cannot be according to horizontal direction corneal position alignment modules 300
Judge whether corneal vertex Ec is on the primary optical axis at eye optical system place.Only comprehensive vertical direction angle
Film location alignment modules 200 and horizontal direction corneal position alignment modules 300, could judge that corneal vertex Ec is
No it is on system primary optical axis.
Step S101 can only judge whether corneal vertex Ec is on the primary optical axis of eye optical system, but this
Time can't determine corneal vertex Ec whether be in system arrange operating position on, it is therefore desirable to perform step
S102.With reference to Fig. 4 and Fig. 5, operating position described herein refers to vertical direction corneal position alignment modules
200 go out light light path primary optical axis and the first joint A1 that light-receiving optical path primary optical axis crosses or horizontal direction angle
Film location alignment modules 300 go out light light path primary optical axis and the second joint A2 that light-receiving optical path primary optical axis crosses.
Step S102: according to described vertical direction corneal position alignment modules or described horizontal direction cornea position
Put alignment modules and judge that corneal vertex is in the front or behind of the operating position that system is arranged.Due in step
In rapid S101, vertical direction corneal position alignment modules 200 and horizontal direction corneal position alignment are utilized
Corneal vertex Ec has been adjusted to the primary optical axis of eye optical system by module 300, the most in step s 102,
Have only to judge the front or behind that corneal vertex Ec is in the operating position that system is arranged.
The concrete decision method of step S102 is as follows.
Reference Fig. 6 also combines Fig. 2 and Fig. 3.In figure 6, the first hot spot 204a is in vertical direction alignment
The upper portion of the vertical centrage L208a of the first receiving plane 208a of light path detector 208, illustrates cornea
Summit Ec from connect mesh object lens 112 excessively close to, i.e. corneal vertex Ec is positioned at rear, operating position.Additionally it is in institute
The the first hot spot 204a stating the vertical centrage L208a first half deviates vertical direction optical system for alignment detector 208
Center O208 the most remote, then illustrate described corneal vertex Ec be positioned at rear, operating position and deviation the most remote, i.e.
Corneal vertex Ec from connect mesh object lens 112 more close to；First hot spot 204a is in the detection of vertical direction optical system for alignment
The lower half of the vertical centrage L208a of device 208, then explanation corneal vertex Ec is from connecing mesh object lens 112 too far,
I.e. corneal vertex Ec is positioned at front, operating position.Additionally it is in the perpendicular of vertical direction optical system for alignment detector 208
First hot spot 204a deviation vertical direction optical system for alignment detector 208 of the lower half of straight centrage L208a
Center is the most remote, then illustrate that described corneal vertex Ec is positioned at front, operating position and deviation is the most remote, i.e. corneal vertex
Ec from connect mesh object lens 112 more away from.
It is horizontally oriented the second receiving plane of optical system for alignment detector 308 with reference to Fig. 8, the second hot spot 304a
The left half part of the horizontal center line L308b of 308a, illustrate corneal vertex Ec from connecing mesh object lens 112 too far,
I.e. corneal vertex Ec is positioned at front, operating position.Additionally it is horizontally oriented the of optical system for alignment detector 308
Second hot spot 304a of the left side of the horizontal center line L308b of two receiving plane 308a deviates horizontal direction pair
The center O308 of quasi-optical road detector 308 is the most remote, then explanation corneal vertex Ec be positioned at front, operating position and
Deviate the most remote, i.e. corneal vertex Ec from connect mesh object lens 112 more away from；Second hot spot 304a is horizontally oriented
The right-hand part of the horizontal center line L308b of optical system for alignment detector 308, then explanation corneal vertex Ec is from connecing mesh
Object lens 112 are the nearest, i.e. corneal vertex Ec is positioned at rear, operating position.Additionally horizontal direction optical system for alignment detection
Second hot spot 304a deviation horizontal direction optical system for alignment of the right-hand part of the horizontal center line L308b of device 308 is visited
The center O308 surveying device 308 is the most remote, then explanation corneal vertex Ec is positioned at rear, operating position and deviation is the most remote,
I.e. corneal vertex Ec from connect mesh object lens 112 more close to.
It should be noted that corneal vertex Ec described above is positioned at front, described operating position refers to cornea
Summit Ec is from horizontal direction corneal position alignment modules 300 or vertical direction corneal position alignment modules 200
Too far, human eye need to be to horizontal direction corneal position alignment modules 300 or vertical direction corneal position to quasi-mode
200 pieces near corneal vertex Ec could move to described operating position；After corneal vertex Ec is positioned at operating position
Side refers to corneal vertex Ec from horizontal direction corneal position alignment modules 300 or vertical direction corneal position
Alignment modules 200 is the nearest, and human eye need to be away from horizontal direction corneal position alignment modules 300 or vertical direction
Corneal vertex Ec could be moved to operating position by corneal position alignment modules 200.
Comprehensive judgement above, according to vertical direction corneal position alignment modules 200 or horizontal direction cornea
Position alignment module 300, can judge that corneal vertex Ec along being positioned on the primary optical axis of eye optical system is
The front or behind of the operating position that system is arranged.It should be noted that operating position referred to is the
One joint A1 or the second joint A2.
Step S103: described corneal vertex is moved to described operating position by control system.
Step S101 determined corneal vertex Ec and is in the primary optical axis of eye optical system；Step S102 is sentenced
Determine corneal vertex Ec and be positioned at the front or behind of the operating position that system is arranged, and the distance away from operating position
Also can draw in the lump；After experienced by step S101 and S102, the realization of step S103 is to be controlled by manipulation
Upper and lower, the left and right of sample preparation product arm component 400 (see Fig. 2) and front and back corneal vertex Ec is moved on to operating position,
Will corneal vertex Ec and the first joint A1 overlap or corneal vertex Ec and the second joint A2 overlap.
Specifically, system regulates the upper and lower, left of sample arm assembly 400 according to the most described corneal vertex alignment principles
Right and front and back, corneal vertex Ec is adjusted to the first joint A1 or the second joint A2.When system control
Time before and after sample arm assembly 400, the sample arm assembly 400 light path to optical fundus Er can be changed, thus system
The movement of Synchronization Control light modulation journey module 1080 can compensate the change of light path of sample arm assembly 400, all the time
Keep from fiber coupler 102 to human eye optical fundus Er with to reference arm reflecting mirror 105 aplanatism, thus all the time
Obtain the OCT image on optical fundus.Once system controls sample arm assembly 400, and corneal vertex Ec is adjusted to first
During joint A1 or the second joint A2, system just can determine which width optical fundus OCT that currently gathered is
Image.Then system just can stop gathering and the judgement work of corneal vertex.It is adjusted to work again from corneal vertex Ec
Make optical fundus OCT image corresponding during the that is first joint A1 or the second joint A2 of position according to described people
Axis oculi light path value calculating method records axis oculi optical path length.
Further, before step S101 is carried out, also comprise the steps:
S201: regulate pupil center location according to iris imaging system, described pupil center location is substantially adjusted to
On system primary optical axis；
S202: regulation probe front and back position, is adjusted to iris picture more visible level, now judges described cornea top
Point is near the operating position that described system is arranged.
The purpose of S201 and S202 is the rough adjustment on corneal summit, for step S101-step below
In S103, accurately adjusting of corneal vertex is prepared.
Specifically, the realization of " iris picture is adjusted to more visible level " in step S202 is by manually
Or control system controls around described regulation sample arm assembly and moves up and down, by described cornea
Summit moves near the operating position that described system is arranged.
This two step and step S101-step S103, it is achieved that be accurately adjusted to corneal vertex Ec to specify
Operating position, it is achieved that the accurate alignment of corneal vertex Ec, the collection for optical fundus OCT image provides the foundation.
After corneal vertex Ec realizes accurately being directed at, now control system 107 allows and surveys people's axis oculi optical path length
OCT system starts to gather signal.By the movement of light modulation journey module 1080 (see Fig. 2), change sample arm group
The light path of part 400 so that from fiber coupler 102 to the light path of optical fundus Er and to reference arm reflecting mirror 105
Light path coupling, thus obtain the OCT image on optical fundus.
System also can allow the position of reference arm reflecting mirror 105 move to change light path, if it does, sample ami light
Road focusing lens 108 is no need for mobile.
(2), corneal vertex is to Barebone
With reference to Fig. 2, the present invention also disclosed corneal vertex to Barebone 500, including vertical direction corneal position
Alignment modules 200, horizontal direction corneal position alignment modules 300.Wherein, horizontal direction corneal position alignment
Go out light light path primary optical axis and the light-receiving optical path primary optical axis of module 300 constitute horizontal plane；Vertical direction cornea position
That puts alignment modules 200 goes out light light path primary optical axis and light-receiving optical path primary optical axis composition perpendicular.Described level
The intersection of plane and perpendicular is eye optical system primary optical axis.
Further, with reference to Fig. 3, vertical direction corneal position alignment modules 200 includes: be arranged on out light light
Vertical direction alignment light source 201 on the primary optical axis of road, vertical direction collecting lens 202, vertical direction go out light light
Door screen 203, vertical direction pinhole plate 204 and vertical direction luminous lens 205 and be arranged on light-receiving optical path primary optical axis
On vertical direction receive lens 207 and vertical direction optical system for alignment detector 208；Horizontal direction corneal position
Alignment modules 300 includes being arranged on out the horizontal direction alignment light source 301 of light light path primary optical axis, horizontal direction is gathered
Optical lens 302, horizontal direction go out light diaphragm 303, horizontal direction pinhole plate 304 and horizontal direction luminous lens
305 receive lens 307 and the detection of horizontal direction optical system for alignment with the horizontal direction being arranged on light-receiving optical path primary optical axis
Device 308.Vertical direction corneal position alignment modules 200 and the merit of horizontal direction corneal position alignment modules 300
Can be the same with aforementioned, tired stating is not done at this.
Further, with reference to Fig. 4, vertical direction corneal position alignment modules 200 also includes being arranged on described erecting
Nogata is to the vertical optical filter 206 receiving lens 207 front end；Horizontal direction corneal position alignment modules 300 is also
Including the horizontal optical filter 306 being arranged on described horizontal direction reception lens 307 front end.Vertically optical filter 206
Effect with horizontal optical filter 306 with front chat the same, do not do tired stating at this.
Further, with reference to Fig. 3, Fig. 4, Fig. 5-Fig. 8, described vertical direction optical system for alignment detector 208
The first receiving plane 208a center o208 and the first joint A1 relative to vertical direction receive lens 207
Conjugation, the first joint A1 and described vertical direction pinhole plate 204 are relative to vertical direction luminous lens 205
Conjugation；The center O308 and of the second receiving plane 308a of described horizontal direction optical system for alignment detector 308
Two joint A2 receive lens 307 relative to horizontal direction and are conjugated, the second joint A2 and horizontal direction pin
Orifice plate 304 is conjugated relative to horizontal direction luminous lens 305.It should be noted that vertical direction is to quasi-optical
First receiving plane 208a of road detector 208 and the second receiving plane of horizontal direction optical system for alignment detector 308
The function at the center of 308a with front chat the same, do not do tired stating at this.
The system of corneal vertex alignment is capable of being directed at, for people the operating position of corneal vertex Ec and setting
Accurately measuring of axis oculi light path value provides guarantee.
(3) the OCT system of people's axis oculi optical path length, is surveyed
Reference Fig. 2, Fig. 2 are the index path of the OCT system surveying people's axis oculi optical path length, including: OCT system
Light source 101, fiber coupler 102, reference arm assembly 1050, detection system 106, control system 107 and
Sample arm assembly 400, this sample arm assembly 400 comprises corneal vertex to Barebone 500.OCT system source
The light of 101 outputs carries to sample arm assembly 400 and reference arm assembly 1050 respectively through fiber coupler 102
For light.That road light through sample arm assembly 400 provides light to tested human eye optical fundus Er, from optical fundus Er
Scattering return light after sample arm assembly 400 with the light reflected from reference arm assembly 1050 at optical fiber
Bonder 102 interferes, interferes light to be detected system 106 and detect, then at control system 107
Reason, finally demonstrates the OCT image of sample.Wherein Barebone 500 is included erecting by corneal vertex
Nogata is to corneal position alignment modules 200, horizontal direction corneal position alignment modules 300.Corneal vertex is directed at
Corneal vertex Ec is adjusted to the operating position that system is arranged, the most foregoing first joint by system 500
A1 or the second joint A2.Owing to the OCT system of this survey people's axis oculi optical path length contains vertical direction angle
Film location alignment modules 200 and horizontal direction corneal position alignment modules 300, for realizing surveying people's axis oculi optical length
Degree provides an important prerequisite, that is, corneal vertex Ec must be adjusted to the working position that system is arranged accurately
Put.
Further, sample arm assembly 400 also includes the Polarization Controller 103 being successively set in light path, adjusts
Light path module 108, X-direction light path scanning means 109, Y-direction light path scanning means 110 and diopter are adjusted
Joint mirror 111.Polarization Controller 103 is arranged near fiber coupler 102, and diopter regulation mirror 111 then leans on
Proximity mesh object lens 112 are arranged.
Additionally the axis oculi optical path length of different human eyes is different, and for realizing the coherent measurement of OCT system, system is joined
It is fixed for examining arm, now need to introduce light path regulatory mechanism in sample arm light path.Native system uses and allows
The adjustable scheme of spacing between sample arm light path focusing lens 108 and X-direction scanning means 109, expires
The needs of foot different people axis oculi optical path length detection, the position i.e. adjusting light modulation journey module 1080 realizes.Separately
Outward, adjusting light modulation journey module 1080 and also include sample arm optical fiber head (not shown), it and sample arm light path are adjusted
The position of focus lens 108 is changeless, say, that adjusts light modulation journey module 1080 and is changing light path
During, sample arm light path focusing lens 108 and sample arm optical fiber head are to move as an entirety,
And the relative position between them keeps constant.
(4), the measurement of axis oculi optical path length
When corneal vertex Ec is adjusted to OCT system by the method and system utilizing aforementioned described corneal vertex alignment
Behind system assigned work position, the data of the axis oculi optical path length recorded are more accurate.Concrete, axis oculi optical length
The relevant parameter that degree is measured is with reference to Fig. 9 and combines Fig. 2 and Fig. 3.When light modulation journey module 1080 is in reset position
When putting (not shown), the relevant original position such as grade of system reference arm is positioned at RDK1.Wherein characterize at RDK1
When system sample arm light modulation journey module 1080 is in reset position, the image apex of OCT system scanning imagery
Corresponding locus, and the distance of RDK1 and the eye cornea summit Ec being in operating distance
LRDK1toEc can be obtained by system calibrating.
When measuring measured optical fundus OCT image, due to the difference of human eye axis oculi optical path length, tester can
Control and regulation light modulation journey module 1080 obtains optical fundus OCT image.Such as, when surveying optical fundus OCT image, adjust
Light path module 1080 to X-direction light path scanning means 109 near the distance of S.Now OCT system is scanned into
As the light path of S is also moved in region to human eye rear.In Fig. 9, scanning area top moves to RDK2 from RDK1.
It should be noted that the OCT of 2 rectangle frame sign different parts measures scope in Fig. 9, rectangle frame is simply
The signal region of scanning, physical scan area can be the shapes such as sector, does not limits at this.
Specifically, the measuring process of people's axis oculi optical path length LEye is as follows:
S301: utilize described vertical direction corneal position alignment modules and described horizontal direction corneal position alignment
Corneal vertex is accurately registered on the primary optical axis of OCT system by module, and makes described corneal vertex be in system
The operating position arranged；
The concrete regulating step of S301 and effect are above elaborating, no longer speak more at this.
S302: according to formula LEye=LRDK1toEc+S+hRetinal, records people axis oculi optical path length LEye；
Wherein: what described operating position referred to described vertical direction corneal position alignment modules goes out light light path key light
The first joint that axle and light-receiving optical path primary optical axis cross or described horizontal direction corneal position alignment modules
Go out light light path primary optical axis and the second joint that light-receiving optical path primary optical axis crosses.
Wherein, hRetinal is that the locus corresponding to retina OCT image top is to measured's retina
The light path of central fovea of macula, this value can be obtained by the oculi posterior segment OCT image of gained.LRDK1toEc characterizes
The distance of RDK1 and the eye cornea summit Ec being in operating distance, for the given value of system calibrating.And dim
The amount of movement S of journey assembly 1080, can be obtained by motor moving step length computation and measurement, or pass through magnetic grid
A kind of subsidiary in chi, grating scale, appearance grid chi obtains.Above-mentioned formula
LEye=LRDK1toEc+S+hRetinal simply reflects human eye axial length light path value, but and the actual physiology of human eye
Axial length, can be obtained divided by human eye average eguivalent refractive index by LEye.
Further, with reference to Fig. 2, light modulation journey assembly 1080 includes driving means (not shown) and by driving
Dynamic device drives the sample arm light path focusing lens 108 and sample arm optical fiber head (not shown) being synchronized with the movement.Logical
Cross and utilize vertical direction corneal position alignment modules 200 and the angle of horizontal direction corneal position alignment modules 300
Barebone is measured people's axis oculi optical path length by film summit, improves the accuracy of test result.
It should be noted that the first described joint A1 and the second joint A2 has been described above in the preceding article,
It is not repeated at this.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all at this
Any amendment, equivalent and the improvement etc. made within bright spirit and principle, should be included in the present invention
Protection domain within.
Claims (12)
1. the method for a corneal vertex alignment, it is characterised in that comprise the steps:
First receiving plane of the vertical direction optical system for alignment detector according to vertical direction corneal position alignment modules
On the image received, the first hot spot of display is on the vertical centrage of described first receiving plane, determines institute
State corneal vertex to be on the perpendicular at eye optical system primary optical axis place；According to horizontal direction cornea position
On the image that second receiving plane of the horizontal direction optical system for alignment detector putting alignment modules receives the of display
Two hot spots are on the horizontal center line of described second receiving plane, determine that described corneal vertex is in described ophthalmology
On the horizontal plane at optical system primary optical axis place；It is in described perpendicular and described water according to corneal vertex
Average, determine that described corneal vertex is on described eye optical system primary optical axis；
According to described vertical direction corneal position alignment modules or described horizontal direction corneal position to quasi-mode
Block, determines that corneal vertex is in the front or behind of the operating position that described eye optical system is arranged；
Described corneal vertex is moved to described operating position by control system；
Wherein, what described operating position referred to described vertical direction corneal position alignment modules goes out light light path key light
The first joint that axle and light-receiving optical path primary optical axis cross or described horizontal direction corneal position alignment modules
Go out light light path primary optical axis and the second joint that light-receiving optical path primary optical axis crosses；The master of described eye optical system
Optical axis is described vertical direction corneal position alignment modules and the phase of described horizontal direction corneal position alignment modules
Intersection.
2. the method for corneal vertex alignment as claimed in claim 1, it is characterised in that: described basis is vertical
The image that first receiving plane of the vertical direction optical system for alignment detector of deflection film location alignment modules receives
First hot spot of upper display is on the vertical centrage of described first receiving plane, determines at described corneal vertex
On the perpendicular at described eye optical system primary optical axis place；According to horizontal direction corneal position to quasi-mode
On the image that second receiving plane of the horizontal direction optical system for alignment detector of block receives at the second hot spot of display
On the horizontal center line of described second receiving plane, determine that described corneal vertex is in described eye optical system
Concretely comprising the following steps on the horizontal plane at primary optical axis place:
Described vertical direction corneal position alignment modules and described horizontal direction corneal position alignment modules are set；
Described vertical direction corneal position alignment modules includes that being arranged on it goes out the vertical direction pair on light light path primary optical axis
Quasi-optical source, vertical direction collecting lens, vertical direction go out light diaphragm, vertical direction pinhole plate and vertical direction
Luminous lens, and the vertical direction that is arranged on its light-receiving optical path primary optical axis receives lens and described vertical side
To optical system for alignment detector；Described horizontal direction corneal position alignment modules includes that being arranged on it goes out light light path master
The horizontal direction alignment light source of optical axis, horizontal direction collecting lens, horizontal direction go out light diaphragm, horizontal direction
Pinhole plate and horizontal direction luminous lens, and it is arranged on the horizontal direction reception of its light-receiving optical path primary optical axis thoroughly
Mirror and described horizontal direction optical system for alignment detector；
The primary optical axis going out light light path of described vertical direction corneal position alignment modules and the primary optical axis of light-receiving optical path
Constitute described perpendicular；The primary optical axis going out light light path of described horizontal direction corneal position alignment modules and being subject to
The primary optical axis of light light path constitutes described horizontal plane；Described first joint and the second joint are in described
On the primary optical axis of eye optical system.
3. the method for the corneal vertex alignment as according to any one of claim 1-2, it is characterised in that: institute
State the first joint and described second joint overlaps.
4. the method for the corneal vertex alignment as according to any one of claim 1-2, it is characterised in that: root
Angle is determined according to described vertical direction corneal position alignment modules or described horizontal direction corneal position alignment modules
The concrete grammar of the front or behind that film summit is in the operating position that described eye optical system is arranged is:
Described first hot spot is in the first half and the deviation of the vertical centrage of described vertical direction optical system for alignment detector
The center of vertical direction optical system for alignment detector is the most remote, then illustrate that described corneal vertex is positioned at rear, operating position
And deviation is the most remote；Described first hot spot is in the vertical centrage of described vertical direction optical system for alignment detector
The center of lower half and deviation vertical direction optical system for alignment detector is the most remote, then illustrate that described corneal vertex is positioned at
Front, operating position and deviation are the most remote；
Described second hot spot be in the horizontal center line of described horizontal direction optical system for alignment detector left side and
The center deviateing described horizontal direction optical system for alignment detector is the most remote, then illustrate that described corneal vertex is positioned at described
Front, operating position and deviation are the most remote；Described second hot spot is in described horizontal direction optical system for alignment detector
The right-hand part of horizontal center line and the center of deviation horizontal direction optical system for alignment detector are the most remote, then explanation is described
Corneal vertex is positioned at rear, operating position and deviation is the most remote；
Wherein, described corneal vertex is positioned at front, described operating position and refers to corneal vertex from horizontal direction angle
Too far, human eye need to be to horizontal direction cornea for film location alignment modules or vertical direction corneal position alignment modules
Position alignment module or vertical direction corneal position alignment modules are near corneal vertex could move to described work
Make position；Described corneal vertex is positioned at rear, operating position and refers to corneal vertex from horizontal direction corneal position
Alignment modules or vertical direction corneal position alignment modules are the nearest, and human eye need to be away from horizontal direction corneal position
Corneal vertex could be moved to operating position by alignment modules or vertical direction corneal position alignment modules.
5. the method for the corneal vertex alignment as according to any one of claim 1-2, it is characterised in that
Step: determine that corneal vertex is in eye optical system primary optical axis according to vertical direction corneal position alignment modules
On the perpendicular at place；Determine that corneal vertex is in ophthalmology light according to horizontal direction corneal position alignment modules
On the horizontal plane at system primary optical axis place, determine that corneal vertex is on eye optical system primary optical axis it
Before, also comprise the steps:
Regulate pupil center location according to iris imaging system, pupil center location is substantially adjusted to opticianry
On system primary optical axis；
Iris picture is adjusted to more visible level, now determines that described corneal vertex is in described eye optical system
Near the operating position arranged.
6. the method for corneal vertex alignment as claimed in claim 5, it is characterised in that: described by iris picture
Being adjusted to more visible level is to be realized by the position of regulation sample arm assembly, and its concrete regulating step is:
Around controlling described regulation sample arm assembly by artificial or control system and move up and down,
Described corneal vertex is moved near the operating position that described eye optical system is arranged.
7. the system of a corneal vertex alignment, it is characterised in that including: vertical direction corneal position is directed at
Module and horizontal direction corneal position alignment modules, described vertical direction corneal position alignment modules includes vertically
Direction optical system for alignment detector, described horizontal direction corneal position alignment modules includes horizontal direction optical system for alignment
Detector；Described vertical direction optical system for alignment detector is used for: detected by described vertical direction optical system for alignment
On the image that first receiving plane of device receives display the first hot spot be in described first receiving plane vertical in
On heart line, determine that described corneal vertex is on the perpendicular at eye optical system primary optical axis place；Described
Horizontal direction optical system for alignment detector is used for: by the second reception of described horizontal direction optical system for alignment detector
On the image that face receives, the second hot spot of display is on the horizontal center line of described second receiving plane, determines
Described corneal vertex is in the horizontal plane at described eye optical system primary optical axis place；Described vertical direction angle
Film location alignment modules and described horizontal direction corneal position alignment modules are provided commonly for determining that corneal vertex is in
On system primary optical axis.
8. the system of corneal vertex alignment as claimed in claim 7, it is characterised in that: described vertical direction angle
Film location alignment modules also includes: be arranged on out the vertical direction alignment light source on light light path primary optical axis, vertically
Direction collecting lens, vertical direction go out light diaphragm, vertical direction pinhole plate and vertical direction luminous lens, with
And the vertical direction being arranged on light-receiving optical path primary optical axis receives lens；Described horizontal direction corneal position is directed at
Module also include being arranged on out the horizontal direction alignment light source of light light path primary optical axis, horizontal direction collecting lens,
Horizontal direction goes out light diaphragm, horizontal direction pinhole plate and horizontal direction luminous lens, and is arranged on light light
The horizontal direction of road primary optical axis receives lens；Described vertical direction corneal position alignment modules go out light light path master
Optical axis and light-receiving optical path primary optical axis are intersected in the first joint, described horizontal direction corneal position alignment modules
Go out light light path primary optical axis and light-receiving optical path primary optical axis is intersected in the second joint；Described first joint and described
Second joint is on the primary optical axis of described eye optical system.
9. the system of corneal vertex alignment as claimed in claim 8, it is characterised in that: described vertical direction angle
Film location alignment modules also includes that being arranged on described vertical direction receives the vertical optical filter of lens front；Described
Horizontal direction corneal position alignment modules also includes that being arranged on described horizontal direction receives the level filter of lens front
Mating plate.
10. survey an OCT system for people's axis oculi optical path length, including: OCT system source, optical fiber couple
Device, detection system, control system, sample arm assembly and reference arm assembly；Described OCT system source is through light
Fine bonder provides incident illumination, wherein through described to described sample arm assembly and described reference arm assembly respectively
The incident light beam strikes of sample arm assembly is to human eye optical fundus and through human eye fundus reflex, and the light reflected is through institute
Occur dry after stating sample arm assembly in described fiber coupler with the light reflected from described reference arm assembly
Relate to, interfere light to be detected system and detect, after control system processes, obtain the OCT fault imaging of human eye,
It is characterized in that: described sample arm assembly includes being arranged on the corneal vertex of end to Barebone, described cornea
Summit includes vertical direction corneal position alignment modules and horizontal direction corneal position alignment modules to Barebone；
Described vertical direction corneal position alignment modules includes vertical direction optical system for alignment detector, described horizontal direction
Corneal position alignment modules includes horizontal direction optical system for alignment detector；Described vertical direction optical system for alignment detects
Device is used for: by showing on the image that the first receiving plane of described vertical direction optical system for alignment detector receives
The first hot spot be on the vertical centrage of described first receiving plane, determine that corneal vertex is in opticianry
On the perpendicular at system primary optical axis place；Described horizontal direction optical system for alignment detector is used for: by described
On the image that second receiving plane of horizontal direction optical system for alignment detector receives, the second hot spot of display is in institute
State on the horizontal center line of the second receiving plane, determine that described corneal vertex is in described eye optical system key light
The horizontal plane at axle place；Described vertical direction corneal position alignment modules and described horizontal direction corneal position
Alignment modules is provided commonly for determining that corneal vertex is on system primary optical axis.
The 11. OCT systems surveying people's axis oculi optical path length as claimed in claim 10, it is characterised in that institute
State sample arm assembly to be additionally included in and set gradually in light path: Polarization Controller, light modulation journey module, X-direction
Scanning means, Y-direction scanning means and diopter regulate mirror and connect mesh object lens；Wherein, described Polarization Control
Device and described fiber coupler are adjacent.
12. 1 kinds of methods surveying people's axis oculi optical path length light path value, it is characterised in that comprise the steps:
Utilize the corneal vertex alignment methods described in claim 1 that corneal vertex is accurately registered to OCT system
On primary optical axis, and described corneal vertex is made to be in the operating position that system is arranged；
According to formula LEye=LRDK1toEc+S+hRetinal, record people axis oculi optical length LEye；
Wherein: what described operating position referred to described vertical direction corneal position alignment modules goes out light light path key light
The first joint that axle and light-receiving optical path primary optical axis cross or described horizontal direction corneal position alignment modules
Go out light light path primary optical axis and the second joint that light-receiving optical path primary optical axis crosses；
LRDK1toEc represents when the light modulation journey assembly of OCT system is in reset position, OCT system scanning imagery
The distance of locus corresponding to the top of image and the corneal vertex being in operating position；S is light modulation journey
The displacement of assembly；HRetinal is that the locus corresponding to retina OCT image top is to measured
The light path of central fovea of macula, described hRetinal is obtained by oculi posterior segment OCT image.
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| JP7080076B2 (en) | 2018-03-16 | 2022-06-03 | 株式会社トプコン | Ophthalmic device and its control method |
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