CN103958445B - 用于放射性药物合成器的校准和归一化系统和方法 - Google Patents

用于放射性药物合成器的校准和归一化系统和方法 Download PDF

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Publication number
CN103958445B
CN103958445B CN201280059332.6A CN201280059332A CN103958445B CN 103958445 B CN103958445 B CN 103958445B CN 201280059332 A CN201280059332 A CN 201280059332A CN 103958445 B CN103958445 B CN 103958445B
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activity
synthesizer
activity detector
data
calibration standard
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Chinese (zh)
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CN103958445A (zh
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T.恩格尔
J.格里格
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GE Healthcare Ltd
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GE Healthcare Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T7/00—Details of radiation-measuring instruments
    • G01T7/005—Details of radiation-measuring instruments calibration techniques
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008—Peptides; Proteins
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Molecular Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nuclear Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measurement Of Radiation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201280059332.6A 2011-09-30 2012-09-28 用于放射性药物合成器的校准和归一化系统和方法 Active CN103958445B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161541246P 2011-09-30 2011-09-30
US61/541,246 2011-09-30
US61/541246 2011-09-30
PCT/US2012/057930 WO2013049577A1 (en) 2011-09-30 2012-09-28 Calibration and normalization systems and methods for radiopharmaceutical synthesizers

Publications (2)

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CN103958445A CN103958445A (zh) 2014-07-30
CN103958445B true CN103958445B (zh) 2015-12-09

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CN201280059332.6A Active CN103958445B (zh) 2011-09-30 2012-09-28 用于放射性药物合成器的校准和归一化系统和方法

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Country Link
US (1) US9523778B2 (https=)
EP (1) EP2760808B1 (https=)
JP (1) JP6018637B2 (https=)
CN (1) CN103958445B (https=)
AU (1) AU2012315757B9 (https=)
ES (1) ES2562656T3 (https=)
WO (1) WO2013049577A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201418893D0 (en) 2014-10-23 2014-12-10 Univ Hull Monolithic body
GB201418899D0 (en) * 2014-10-23 2014-12-10 Univ Hull System for radiopharmaceutical production
GB201418897D0 (en) 2014-10-23 2014-12-10 Univ Hull Methods and apparatus for the analysis of compounds
US10245002B2 (en) * 2017-08-01 2019-04-02 Siemens Medical Solutions Usa, Inc. Isotope specific calibration of a dose calibrator for quantitative functional imaging
CA3093236C (en) * 2018-03-07 2022-04-12 Siemens Medical Solutions Usa, Inc. Calibration bias reduction in a pressurized gas ion chamber-based dose calibrator
SG11202009326XA (en) * 2018-03-28 2020-10-29 Bracco Diagnostics Inc Early detection of radioisotope generator end life
GB201805283D0 (en) * 2018-03-29 2018-05-16 Ge Healthcare Ltd Method of synthesizing a radiopharmaceutical
US11615882B2 (en) 2018-11-07 2023-03-28 Ge Healthcare Limited Apparatus, non-transitory computer-readable storage medium, and computer-implemented method for distributed ledger management of nuclear medicine products

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004100490A2 (de) * 2003-05-07 2004-11-18 Schering Ag Vorrichtung und verfahren zum nucleophilen fluorieren
CN1791807A (zh) * 2003-05-23 2006-06-21 格尔根·尼尔森 放射疗法中的治疗前验证方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070040115A1 (en) * 2005-08-05 2007-02-22 Publicover Julia G Method for calibrating particle beam energy
US9056200B2 (en) * 2008-06-06 2015-06-16 Bayer Medical Care Inc. Apparatus and methods for delivery of fluid injection boluses to patients and handling harmful fluids
US8214159B2 (en) * 2008-12-04 2012-07-03 Siemens Medical Solutions Usa, Inc. Apparatus and method for automated quality control
GB0905328D0 (en) * 2009-03-27 2009-05-13 Ge Healthcare Ltd Indole derivatives
JP6078463B2 (ja) * 2010-04-09 2017-02-08 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ 放射性医薬品の濃度測定システムおよび方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004100490A2 (de) * 2003-05-07 2004-11-18 Schering Ag Vorrichtung und verfahren zum nucleophilen fluorieren
CN1791807A (zh) * 2003-05-23 2006-06-21 格尔根·尼尔森 放射疗法中的治疗前验证方法

Also Published As

Publication number Publication date
ES2562656T3 (es) 2016-03-07
WO2013049577A1 (en) 2013-04-04
US20140243500A1 (en) 2014-08-28
EP2760808A1 (en) 2014-08-06
US9523778B2 (en) 2016-12-20
CN103958445A (zh) 2014-07-30
EP2760808B1 (en) 2015-11-18
AU2012315757A1 (en) 2014-04-17
AU2012315757B2 (en) 2017-11-23
AU2012315757A9 (en) 2018-02-01
AU2012315757B9 (en) 2018-01-25
JP6018637B2 (ja) 2016-11-02
JP2015504412A (ja) 2015-02-12

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