CN103948454B - The overall intravascular stent of branch's controllable type and implanting device thereof - Google Patents

The overall intravascular stent of branch's controllable type and implanting device thereof Download PDF

Info

Publication number
CN103948454B
CN103948454B CN201410179096.2A CN201410179096A CN103948454B CN 103948454 B CN103948454 B CN 103948454B CN 201410179096 A CN201410179096 A CN 201410179096A CN 103948454 B CN103948454 B CN 103948454B
Authority
CN
China
Prior art keywords
stent
sub
main support
implanting device
branch
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201410179096.2A
Other languages
Chinese (zh)
Other versions
CN103948454A (en
Inventor
蒙炜
李涛
卢强
肖正华
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
West China Hospital of Sichuan University
Original Assignee
West China Hospital of Sichuan University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by West China Hospital of Sichuan University filed Critical West China Hospital of Sichuan University
Priority to CN201410179096.2A priority Critical patent/CN103948454B/en
Priority to PCT/CN2014/078306 priority patent/WO2015165135A1/en
Publication of CN103948454A publication Critical patent/CN103948454A/en
Application granted granted Critical
Publication of CN103948454B publication Critical patent/CN103948454B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/844Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents folded prior to deployment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/962Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/954Instruments specially adapted for placement or removal of stents or stent-grafts for placing stents or stent-grafts in a bifurcation

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

The present invention discloses the overall intravascular stent of a kind of branch controllable type and implanting device thereof, comprises main support, sub-stent and implanting device, and sub-stent seamless link is on the lateral wall of main support and UNICOM inner with main support; Main support, sub-stent all have compressive state and deployed condition 2 kinds of forms, when main support, sub-stent are in compressive state, size is less than size when being in deployed condition, main support, sub-stent are in compressive state under the constraint of implanting device, are in deployed condition when departing from implanting device.The present invention supports the main support of main blood vessel by being used for and being used for supporting the sub-stent unitary construction of branch vessel, and by the disposable implantable intravascular of implanting device, can shorten the operating time of implantable intravascular support, alleviate patient suffering, minimizing operative doctor and patient accept time and the dosage of ray.

Description

The overall intravascular stent of branch's controllable type and implanting device thereof
Technical field
The present invention relates to a kind of medical apparatus and instruments, particularly relate to a kind of intravascular stent and implanting device thereof.
Background technology
In intravascular stent implant surgery, there is the situation that main blood vessel and branch vessel thereof all need implant frame, existing method first utilizes implanting device to implant in main blood vessel by the main support supporting main blood vessel, again the sub-stent supporting branch vessel is sent into branch vessel by the main support implanted, need the reserved outlet being applicable to sub-stent and passing on main support wall, and need above-mentioned outlet align fingers blood vessel when implanting main support, operation link is many, time is long, and two support junctions exist the risk of internal hemorrhage due to trauma.Although the support of You Dai branch is reported at present, but this kind of intravascular stent is all rely on to have the mode of wound to cut the lower directly implantation of blood vessel direct-view, lack one and can pass through Wicresoft's intervening mode, the overall intravascular stent of branch's controllable type of the main blood vessel of disposable implantation and branch vessel and corresponding implanting device.
Summary of the invention
The present invention aims to provide the overall intravascular stent of a kind of branch controllable type and implanting device thereof, support the main support of main blood vessel by being used for and being used for supporting the sub-stent unitary construction of branch vessel, and by Wicresoft's intervening mode and the disposable implantable intravascular of implanting device, thus shorten the operating time of implantable intravascular support, alleviate patient suffering, when shortening clinician and corrective surgery, be exposed to the time under ray.
For achieving the above object, the present invention realizes by the following technical solutions:
The overall intravascular stent of branch disclosed by the invention controllable type and implanting device thereof, comprise main support, sub-stent and implanting device, on the lateral wall that described sub-stent is connected to main support and UNICOM inner with main support; Main support, sub-stent all have compressive state and deployed condition 2 kinds of forms, when main support, sub-stent are in compressive state, size is less than size when being in deployed condition, main support, sub-stent are in compressive state under the constraint of implanting device, are in deployed condition when departing from implanting device.Main support, sub-stent send into Ink vessel transfusing by implanting device, and after arriving precalculated position, remove the constraint to sub-stent, main support when taking out implanting device, sub-stent and main support support branch vessel and main blood vessel when deployed condition.
Preferably, described implanting device comprises interior sheath pipe, outer sheath and seal wire, the external diameter of described interior sheath pipe is less than the internal diameter of outer sheath, interior sheath tube wall offers through hole, described outer sheath front end tube wall has breach, the tube wall of side, described breach place offers platen passageway, described platen passageway and breach UNICOM through outer sheath tube wall in the axial direction, pressing plate is provided with in platen passageway, the through platen passageway of described pressing plate, the front end bifurcated of pressing plate forms 2 pressure arms, described pressure arm part covers breach, gap width between 2 pressure arms meet sub-stent seal wire by.
Further, described interior sheath pipe is supported on main support inside, and described outer sheath parcel is in main support and the sub-stent of compressive state, and the sidewall of sub-stent is stuck in breach, and the top of sub-stent contacts with pressure arm lower surface.
Further, the quantity of described main support is 1, and the quantity of sub-stent is 1 ~ 8, and the quantity of interior sheath pipe is 1, and the quantity of outer sheath is 1, and the quantity of seal wire is sub-stent quantity+1.
Further, described interior sheath pipe is provided with dividing plate vertically, according to branch stent and seal wire quantity, interior sheath pipe is divided into several passages by described dividing plate, number of channels is consistent with seal wire quantity, and one of them passage runs through main support, rest channels and sub-stent UNICOM.
Preferably, the connection of described sub-stent and main support is Hard link or is flexible coupling.When sub-stent and main support Hard link, sub-stent and main support can be integrally manufactured.Being flexible coupling is coating layer by main support surface, is connected to by sub-stent on main support, can reduces the location accuracy requirements of sub-stent, operation when being convenient to operation, controls.
Preferably, the angle between described sub-stent and main support and the angle between branch vessel and main blood vessel suitable.
Preferably, the material of described main support, sub-stent is metal, degradable biomaterial or the multilayer materials etc. such as all kinds of alloy such as all kinds of memorial alloy, medical stainless steel, cochrome, platinum, gold, tantalum such as Ultimum Ti.
Further, according to the difference of material therefor, main support, sub-stent can be bare bracket, surface coating support, degradable biomaterial support or coating stent of medicine.
Preferably, sub-stent length 0.5-8cm (deployed condition), 0-2cm (compressive state), diameter 0.1-4cm (deployed condition), 0.1-3cm (compressive state); Main support length 5-90cm (deployed condition), 5-90cm (compressive state), diameter 0.1-5cm (deployed condition), 0.1-3cm (compressive state).
Preferably, the distance between sub-stent is 0.5-30cm (compressive state).
The overall intravascular stent of branch of the present invention controllable type and implanting device thereof, be applicable to Endovascular interventional treatment, support the main support of main blood vessel by being used for and being used for supporting the sub-stent unitary construction of branch vessel, and by Wicresoft's intervening mode and the disposable implantable intravascular of implanting device, existing separating stent-graft not only can be avoided to occur the risk of internal hemorrhage due to trauma, also contribute to simplifying intravascular stent implant surgery process, shorten operating time, alleviate patient suffering.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of main support deployed condition of the present invention;
Fig. 2 is the schematic diagram of main support compressive state of the present invention;
Fig. 3 is axial section of the present invention;
Fig. 4 is radial section figure of the present invention;
Fig. 5 is rearview of the present invention;
Fig. 6 is top view of the present invention;
In figure: in 1-main support, 2-sub-stent, 3-, sheath pipe, 4-outer sheath, 5-breach, 6-pressing plate, 7-separator channels, 8-dividing plate, 9-branch seal wire, 10-dominate silk, 11-through hole, 61-pressure arm.
Detailed description of the invention
In order to make object of the present invention, technical scheme and advantage clearly understand, below in conjunction with accompanying drawing, the present invention is further elaborated.
As shown in Figure 1 and Figure 2, the overall intravascular stent of branch disclosed by the invention controllable type, comprise main support 1, sub-stent 2, main support 1, sub-stent 2 are tubulose, and sub-stent 2 seamless link is on the lateral wall of main support 1 and UNICOM inner with main support; Main support 1, sub-stent 2 all have squeezed state and release state 2 kinds of forms, and when main support 1, sub-stent 2 are in squeezed state, size is all less than size when being in release state.Main support 1, sub-stent 2 are in squeezed state under the constraint of implanting device, are in release state after departing from implanting device.
As Fig. 3, Fig. 4, Fig. 5, shown in Fig. 6, the present invention also comprises implanting device, implanting device comprises interior sheath pipe 3, outer sheath 4 and seal wire, seal wire comprises leading silk 10 and branch's seal wire 9, the external diameter of interior sheath pipe 3 is less than the internal diameter of outer sheath 4, interior sheath pipe 3 tube wall offers through hole 11, outer sheath front end tube wall has breach 5, the tube wall of side, breach 5 place offers platen passageway 7, platen passageway 7 with breach 5 UNICOM and in the axial direction through outer sheath 4 tube wall, pressing plate 6 is provided with in platen passageway 7, the through platen passageway 7 of pressing plate 6, the front end bifurcated of pressing plate 6 forms 2 pressure arms 61, pressure arm 61 part covers breach 5.Interior sheath pipe 3 is provided with dividing plate 8 vertically, and interior sheath pipe 3 is divided into 2 passages by dividing plate 8, one of them passage and through hole 11 UNICOM.
Before carrying out implant surgery, outer sheath 4 parcel is in the main support 1 of squeezed state, the two opposite side walls being in the sub-stent 2 of squeezed state is stuck in breach 5, pressure arm 61 pushes down the top of sub-stent 2, the mouth of pipe of sub-stent 2 is positioned at directly over through hole 11, namely main support 1 is by the constraint of outer sheath 4, and sub-stent 2 is subject to the constraint of breach 5 and pressing plate 6, is all in compressive state.
During practical operation, first in main blood vessel, leading silk 10 is implanted, implanting device and support entirety is guided to send into main blood vessel, branch's seal wire 9 is adopted to guide sub-stent 2 to arrive the position required, branch's seal wire 9 and leading silk 10 are respectively by dividing plate 8 both sides passage separately, avoid the mutual interference between branch's seal wire 9 and leading silk 10, when sub-stent 2 arrives branch vessel mouth position, sheath pipe 3 in fixing, by branch's seal wire 9 successively through through hole 11, sub-stent 2, branch vessel is sent into behind the gap of two pressure arms 61, then pressing plate 6 is extracted out, sub-stent 2 axis direction is launched, sub-stent 2 enters branch vessel, after sub-stent 2 is adjusted to the right place, exit outer sheath 4 successively, branch's seal wire 9, interior sheath pipe 3 and leading silk 10, make sub-stent 2, main support 1 departs from the constraint of implanting device completely, be returned to the form of deployed condition, support blood vessel.
Certainly; the present invention also can have other various embodiments; when not deviating from the present invention's spirit and essence thereof; those of ordinary skill in the art can make various corresponding change and distortion according to the present invention, but these change accordingly and are out of shape the protection domain that all should belong to the claim appended by the present invention.

Claims (8)

1. the overall intravascular stent of branch's controllable type and an implanting device thereof, is characterized in that, comprise main support, sub-stent and implanting device, on the lateral wall that described sub-stent is connected to main support and UNICOM inner with main support, main support, sub-stent all has compressive state and deployed condition 2 kinds of forms, main support, when sub-stent is in compressive state, size is less than size when being in deployed condition, main support, sub-stent is in compressive state under the constraint of implanting device, deployed condition is in when departing from implanting device, described implanting device comprises interior sheath pipe, outer sheath and seal wire, the external diameter of described interior sheath pipe is less than the internal diameter of outer sheath, interior sheath tube wall offers through hole, described outer sheath front end tube wall has breach, the tube wall of side, described breach place offers platen passageway, described platen passageway and breach UNICOM through outer sheath tube wall in the axial direction, pressing plate is provided with in platen passageway, the through platen passageway of described pressing plate, the front end bifurcated of pressing plate forms 2 pressure arms, described pressure arm part covers breach.
2. the overall intravascular stent of branch according to claim 1 controllable type and implanting device thereof, it is characterized in that: described interior sheath pipe is supported on main support inside, described outer sheath parcel is in main support and the sub-stent of compressive state, the sidewall of sub-stent is stuck in breach, and the top of sub-stent contacts with pressure arm lower surface.
3. the overall intravascular stent of branch according to claim 1 controllable type and implanting device thereof, it is characterized in that: the quantity of described main support is 1, the quantity of sub-stent is 1 ~ 8, and the quantity of interior sheath pipe is 1, the quantity of outer sheath is 1, and the quantity of seal wire is sub-stent quantity+1.
4. the overall intravascular stent of branch according to claim 3 controllable type and implanting device thereof, it is characterized in that: described interior sheath pipe is provided with dividing plate vertically, according to branch stent and seal wire quantity, interior sheath pipe is divided into several passages by described dividing plate, number of channels is consistent with seal wire quantity, one of them passage runs through main support, rest channels and sub-stent UNICOM.
5. the overall intravascular stent of branch according to claim 1 controllable type and implanting device thereof, it is characterized in that: described sub-stent and main support are integrated manufacture, the connection of sub-stent and main support is Hard link or is flexible coupling.
6. the overall intravascular stent of branch according to claim 1 controllable type and implanting device thereof, is characterized in that: the angle between described sub-stent and main support and the angle between branch vessel and main blood vessel suitable.
7. the overall intravascular stent of branch according to claim 1 controllable type and implanting device thereof, is characterized in that: the material of described main support, sub-stent is memorial alloy, medical stainless steel, alloy, platinum, gold, tantalum, degradable biomaterial or multilayer materials.
8. the overall intravascular stent of branch according to claim 1 controllable type and implanting device thereof, is characterized in that: described main support, sub-stent are bare bracket, surface coating support, degradable biomaterial support or coating stent of medicine.
CN201410179096.2A 2014-04-30 2014-04-30 The overall intravascular stent of branch's controllable type and implanting device thereof Expired - Fee Related CN103948454B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201410179096.2A CN103948454B (en) 2014-04-30 2014-04-30 The overall intravascular stent of branch's controllable type and implanting device thereof
PCT/CN2014/078306 WO2015165135A1 (en) 2014-04-30 2014-05-23 Branch controllable type integrated vascular stent and implantation apparatus thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410179096.2A CN103948454B (en) 2014-04-30 2014-04-30 The overall intravascular stent of branch's controllable type and implanting device thereof

Publications (2)

Publication Number Publication Date
CN103948454A CN103948454A (en) 2014-07-30
CN103948454B true CN103948454B (en) 2016-02-10

Family

ID=51325910

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410179096.2A Expired - Fee Related CN103948454B (en) 2014-04-30 2014-04-30 The overall intravascular stent of branch's controllable type and implanting device thereof

Country Status (2)

Country Link
CN (1) CN103948454B (en)
WO (1) WO2015165135A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104840283B (en) * 2015-05-27 2017-03-15 唐利龙 A kind of intravascular stent system with seal wire reserved passageway protection device
JP7479844B2 (en) * 2017-02-24 2024-05-09 ボルトン メディカル インコーポレイテッド Constrainable stent grafts, delivery systems and methods of use - Patents.com
CN109091275B (en) * 2018-08-24 2024-01-30 四川大学 Biodegradable stent
CN109009591B (en) * 2018-08-24 2024-02-27 四川大学 Bioabsorbable stent
CN109009590B (en) * 2018-08-24 2024-04-26 四川大学 Biological trapezoid degradable support
CN110338948A (en) * 2019-08-07 2019-10-18 中国医学科学院北京协和医院 Aortic branch support system
CN113288579B (en) * 2021-06-21 2022-07-12 卢国华 Novel artificial lacrimal duct
CN114504413B (en) * 2022-01-19 2023-08-15 四川大学华西医院 Implantable medical device and implantable medical device kit

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101152109A (en) * 2006-09-27 2008-04-02 黄方炯 Three-collateral bracket vascellum for arcus aortae
CN101897629A (en) * 2009-05-26 2010-12-01 微创医疗器械(上海)有限公司 Branched membrane-covered support conveying system and conveying method thereof
CN201664353U (en) * 2009-11-24 2010-12-08 汤敬东 Aortic split type bracket and double guide wire conveyor thereof
CN103476359A (en) * 2011-04-19 2013-12-25 美敦力瓦斯科尔勒公司 Mobile external coupling for branch vessel connection

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6918925B2 (en) * 2001-03-23 2005-07-19 Hassan Tehrani Branched aortic arch stent graft and method of deployment
US20080243233A1 (en) * 2005-02-08 2008-10-02 B-Balloon Ltd. Device and Methods for Treatment of Vascular Bifurcations
EP2398547A1 (en) * 2009-02-20 2011-12-28 Boston Scientific Scimed, Inc. Torqueable balloon catheter
US8474120B2 (en) * 2009-10-09 2013-07-02 W. L. Gore & Associates, Inc. Bifurcated highly conformable medical device branch access
CN102370528A (en) * 2010-08-09 2012-03-14 郭伟 Bracket type blood vessel
US8574283B1 (en) * 2011-08-30 2013-11-05 Suraj Govind Kamat Deployment of stents within bifurcated vessels

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101152109A (en) * 2006-09-27 2008-04-02 黄方炯 Three-collateral bracket vascellum for arcus aortae
CN101897629A (en) * 2009-05-26 2010-12-01 微创医疗器械(上海)有限公司 Branched membrane-covered support conveying system and conveying method thereof
CN201664353U (en) * 2009-11-24 2010-12-08 汤敬东 Aortic split type bracket and double guide wire conveyor thereof
CN103476359A (en) * 2011-04-19 2013-12-25 美敦力瓦斯科尔勒公司 Mobile external coupling for branch vessel connection

Also Published As

Publication number Publication date
WO2015165135A1 (en) 2015-11-05
CN103948454A (en) 2014-07-30

Similar Documents

Publication Publication Date Title
CN103948454B (en) The overall intravascular stent of branch's controllable type and implanting device thereof
JP5814949B2 (en) Aneurysm surgery device
CN103876860B (en) With the aorta tectorial membrane stent of chimney support supporting pipeline
CN204318826U (en) A kind of novel cage occluder for left auricle
CN101449987B (en) Sacculus conveyer
CN105999517A (en) Balloon catheter
CN201132006Y (en) Multi-layer saccule conduit tube
CN203677329U (en) Novel bracket releasing device
WO2009120021A2 (en) Carina modification catheter
CN104546242A (en) Transporting device of implanting body and implanting medical instrument
CN108742962A (en) A kind of stent delivery system
CN101015478A (en) Collateral covered graft-stent and releasing method thereof
CN204446185U (en) A kind of nanometer electrospinning overlay film etching support for the treatment of intracranial aneurysm
CN105413000A (en) Biliary drainage device
CN102370532B (en) Collateral type tectorial membrane support frame conveyor as well as installing method
CN204017094U (en) A kind of novel T-type drainage tube
US10219707B2 (en) Device for measurement of pressure and administration of drugs in an aneurysm in a blood vessel
WO2021129493A1 (en) Conveyor and lumen apparatus conveying system
CN203710194U (en) Delivery system for abdominal aorta stent
CN204446194U (en) One treats intracranial aneurysm electrolysis de-etching overlay film frame
CN206612865U (en) It is a kind of to stablize recyclable esophageal stents induction system
CN102949225A (en) Visualization endoscopic incision knife device
CN108451678B (en) Suspension type anti-reflux biliary tract stent
CN201481558U (en) Guide wire distributor
CN205459231U (en) Support is put into exchange and is used pipe installation

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20160210

Termination date: 20200430