CN103920212B - Automatic injecting device capable of giving sound indication when injection is completed - Google Patents
Automatic injecting device capable of giving sound indication when injection is completed Download PDFInfo
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- CN103920212B CN103920212B CN201410161876.4A CN201410161876A CN103920212B CN 103920212 B CN103920212 B CN 103920212B CN 201410161876 A CN201410161876 A CN 201410161876A CN 103920212 B CN103920212 B CN 103920212B
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Abstract
The invention relates to an automatic injecting device (1) capable of giving sound indication when injection is completed. The device comprises a container (2), a piston (8), a piston rod (9), a bias pressure mechanism (18), a shell (14) and control mechanisms (13 and 22), wherein the piston rod (9) is connected to the piston (8) in the injecting process, the bias pressure mechanism (18) is used for making the piston rod (9) move to the far side relative to the container (2), the container (2), the piston rod (9) and the bias pressure mechanism (18) are contained in the shell (14), and the control mechanisms (13 and 22) are used for generating sound indication when injection is completed. The device is characterized in that each control mechanism comprises a first element (13) and a second element (22), each first element is flexible or prone to fracture and connected to the shell (14) or the piston rod (9) in the injecting process, each second element is connected to the piston rod (9) or the shell (14) in the injecting process, and the first elements and the second elements cooperate with each other to give sounding indication under the action of the bias pressure mechanism (18) when the injection is completed.
Description
The application be it is entitled " with complete inject the sound indicate automated injection device ", international filing date be 2008
The patent of invention Shen that September 29 days, international application no are PCT/IB2008/003285, national applications number is 200880131863.5
Divisional application please.
Technical field
The present invention relates to a kind of device for automatic injection product, described device guarantees that user is basic by product
On fully inject.
Background technology
In this application, the distal end portion of component or device is understood to refer in proper use of period farthest away from user
The end of hand, and proximal end is understood to refer to the end in proper use of period near user's hand.Similarly, exist
In the application, " distal direction " is used to limit injection direction, and " proximal direction " is used to limit the side contrary with injection direction
To.
Some diseases make periodically（For example, on the basis of daily）Injection medicine or product become required.In order to simplify this
The treatment of a little diseases, has now been developed that some are used for the device of automatic injection to allow patient oneself to be injected.
Certainly, due to patient generally neither nurse nor in terms of medical device educated people, it is this
Device for automatic injection must verified be using very simple and very safe.In particular it is important, that guaranteeing to utilize this
The device of sample is injecting the product of controlled dose, that is to say, that, it is necessary to completely injected.And, in some cases, make
User can extract the device for automatic injection before injection is completed.Therefore, it is important that being apprised of product for user
Product have substantially completely been injected and user can be from injection site extracting apparatus.
Known a kind of automated injection device from patent application WO2007/132353, wherein sound is in whole injection process
In send, so as to when sound stops indicate patient injection complete.
Need the self-injection device that can clearly indicate that user's injection is completed.
The content of the invention
The present invention meets this needs by proposing the alternative of said apparatus.The present invention proposes a kind of for producing
Product automatic injection enters the device of injection site, and described device produces sound instruction when injection is completed.
The present invention relates to a kind of device for product automatic injection to be entered injection site, the product is carried by container,
The container has open proximal end and carries the substantially closed distal end portion and piston of pin, and the pin is from institute
The product for stating container provides outlet, and the piston is arranged in the container and can distad transport relative to the container
Dynamic, the piston distal movement makes the product discharge from the container by the pin, so as to realize the product
Injection, described device includes：
- piston rod, the piston rod is used to be attached to the piston along distal direction in injection process,
- bias mechanism, the bias mechanism is used to make the piston rod relative to the container to remote in injection process
Lateral movement,
- housing, the housing design is used to receive the container, the piston rod and the bias machine at least in part
Structure,
- controlling organization, the controlling organization is designed for when the piston is located near the distal end portion of the container
And produce the sound when product is substantially completely discharged from the container to indicate, so as to provide the product for user
The instruction that product injection is completed,
Described device is characterised by：
The controlling organization includes at least one first elements and at least one second elements, and first element is can
Scratch either easy fracture and the housing or the piston rod are directly or indirectly attached in injection process, it is described
Second element is directly or indirectly attached to the piston rod or the housing in injection process, described first and second yuan
Coordination with one another is indicated part with producing the sound at the end of injection in the presence of the bias mechanism.
The device of the present invention allows user clearly to be informed that injection is completed.
In this application, mean that, when making A move in X direction, A is attached to B by statement " A is attached in X direction B ".Change
Sentence is talked about, if making A move in X direction, then B is moved in X direction under the pulling of A.
In this application, meant by the way that A is attached directly to into B, Huo Zhetong by statement " A is directly or indirectly attached to B "
A is attached to B by the intermediate member for crossing link A to B（Connection indirectly）It is fixed relative to each other A and B.
In one embodiment of the invention, first element is different from the bias mechanism.
In one embodiment of the invention, first element includes that free position can be deflected into from depressed position
At least one part that can radially bend, the part that can radially bend is produced when its free position is moved on to from its depressed position
Raw sound, second element includes at least one against surface, it is described against surface on the part that can radially bend
Apply stress so that the part that can radially bend is placed in into its depressed position before injection terminates, and make described against table
Face discharges at the end of injection the stress in the presence of the bias mechanism.
For example, at the end of injection, the part that can radially bend is being applied to by bias mechanism or against on surface
Active force under, the part that can radially bend departs from described against surface, or it is described against surface depart from it is described can footpath
To the part of flexure, the part produces sound to the frictional force on the surface.In embodiment, additional sound can be produced
Sound, for example by the part that can radially bend, when its free position is returned to, making contact surface is additional so as to produce
Sound.
In one embodiment of the invention, the piston rod includes hollow cylinder, and the hollow cylinder is in its proximal end
Be provided with neck ring, the wall of the neck ring can outward radial flexure, and described device further included in injection process
Relative to the longitudinal rod that the housing is fixed, the longitudinal rod is spaced apart relative to the piston rod proximad, the longitudinal rod
Distal end portion be slidingly received in the hollow cylinder and be provided with projection, the projection has more than the neck ring
The overall diameter of interior diameter, the wall of the part that can radially bend including the neck ring and described includes institute against surface
Projection is stated, the projection applies stress before injection terminates on the wall of the neck ring, and by the bias mechanism
Effect is lower to be departed from the neck ring and the stress is discharged at the end of injection.
In such an embodiment, when the projection departs from described under the active force applied by the bias mechanism
During neck ring, friction of the projection in the neck ring produces sound.Therefore, user is apprised of injection and completes.
In another embodiment of the present invention, the part that can radially bend includes that at least one deflection is longitudinally propped up
Leg, the deflection longitudinal direction supporting leg is described against surface bag with the proximal end and free distal end portion for being fixed to the housing
Include the outer wall of the piston rod, described in the wall contacts of the piston rod deflection longitudinal direction supporting leg distal end portion and note
Penetrate and the distal end portion for being stressed in deflection longitudinal direction supporting leg is applied before terminating to deflect it into its depressed position, the piston
The outer wall of bar is discharged by departing from deflection longitudinal direction supporting leg in the presence of the bias mechanism at the end of injection
The stress.
In another embodiment of the present invention, the part that can radially bend includes that at least one deflection is longitudinally propped up
Leg, deflection longitudinal direction supporting leg has the distal end portion being fixed on the outer wall of the piston rod, described to include institute against surface
Longitudinal projection of inner walls is stated, longitudinal projection contacts the proximal end of deflection longitudinal direction supporting leg and terminates in injection
Before apply the proximal end for being stressed in deflection longitudinal direction supporting leg to deflect it into its depressed position, longitudinal projection is led to
Cross and depart from deflection longitudinal direction supporting leg in the presence of the bias mechanism stress is discharged at the end of injection.
The device of the present invention may further include the contact surface being positioned on the inwall of the housing, the deflection
Longitudinal supporting leg collides the contact surface when its free position is returned to so as to produce sound.
In another embodiment of the present invention, first element includes easy fracture part, the easy fracture part tool
There are the proximal end for being directly or indirectly attached to the housing, and the distally for being directly or indirectly attached to the piston rod
End, makes the easy fracture part rupture so as to produce sound at the end of injection in the presence of the bias mechanism.
In one embodiment of the invention, the easy fracture part includes flexible with proximal end and distal end portion
Wire rod, the proximal end of the flexible wire rod is fixed to the fixing point being positioned in the housing proximal region, in injection
During the fixing point fix relative to the housing, and the distal end portion of the flexible wire rod is fixed to the piston
The proximal end of bar, the length of the flexible wire rod is less than the proximal end of the piston rod and institute at the end of injection
The separate distance of fixing point is stated, piston rod distal movement in the presence of the bias mechanism makes described flexible
Wire rod ruptures at the end of injection.For example, but the wire rod can be made up of the material of rigid or semi-rigid easy fracture.
In one embodiment, the wire rod is made up of nylon or polypropylene.
In another embodiment of the present invention, the piston rod includes hollow cylinder, and the hollow cylinder is in its nearside
End is provided with neck ring, and the easy fracture part includes the rigid cable with proximal end and distal end portion, the rigid cable it is near
Side is fixed to the fixing point being positioned in the housing proximal region, and the fixing point is in injection process relative to the shell
Body is fixed, and the distal end portion of the rigid cable is slidingly received in the hollow cylinder, the institute of the rigid cable
State distal end portion and be provided with projection, the projection has the overall diameter of the interior diameter more than the neck ring, the length of the rigid cable
Degree is less than the distance that the neck ring and the fixing point of the piston rod are separate at the end of injection, and the piston rod is in institute
Stating distal motion in the presence of bias mechanism makes the rigid cable rupture at the end of injection.For example, the rigid cable
Can be made up of easy fracture material.In one embodiment, the rigid cable is made up of polypropylene.
Description of the drawings
The device of the present invention is described further referring now to following description and drawings, in the accompanying drawings：
Fig. 1 is one embodiment of apparatus of the present invention using front longitudinal sectional view；
Fig. 2 is the partial sectional view of the device of Fig. 1, shows position of the controlling organization before injection terminates；
Fig. 3 is longitudinal sectional view of the device of Fig. 1 at the end of injection；
Fig. 4 is second embodiment of apparatus of the present invention using front longitudinal sectional view；
Fig. 5 is the partial sectional view of the device of Fig. 4, position of the display control mechanism before injection terminates；
Fig. 6 is longitudinal sectional view of the device of Fig. 4 at the end of injection；
Fig. 7-9 be the 3rd embodiment of apparatus of the present invention controlling organization respectively using it is front, injection terminate before
In injection process, and the partial sectional view at the end of injection；
Figure 10 a and 10b be the 4th embodiment of apparatus of the present invention controlling organization respectively using it is front and injection knot
Partial sectional view during beam；
Figure 11 is the partial sectional view in injection process of the 5th embodiment of apparatus of the present invention before injection terminates.
Specific embodiment
With reference now to accompanying drawing, will be described in the present invention.Fig. 1 shows the device for automatic injection of the invention
One embodiment longitudinal sectional view, now device be in use premise supply user when state, and with
It is referred to as device 1 in lower description.Device 1 includes container 2, and the container has nearside open end 3, substantially closing with pin 5
The distal end portion 4 of conjunction；Container 2 carries the product 6 that be injected into injection site 7.Container 2 is provided with outward flange in its proximal end
2a.Piston 8 is arranged in container 2 and can move relative to the container 2.As will hereinafter appear, piston 8 is along distally
The motion in direction will be such that product 6 discharges from container 2.Device 1 also includes piston rod 9：As will hereinafter appear, piston rod 9
Piston 8 is attached in injection process along distal direction.
In the example shown in Fig. 1-3, piston rod 9 includes hollow cylinder 10, and the hollow cylinder has in its distal end portion
Flange 11 and there is neck ring 12 in its proximal end, the interior diameter of the interior diameter of the neck ring 12 less than the hollow cylinder 10.
Neck ring 12 is provided with outward flange 12a in its proximal end.The wall 13 of neck ring 12 can outward radial flexure, that is to say, that neck
The interior diameter of ring 12 can around the inner surface of wall 13 for putting on the neck ring 12 on stress lower edge centrifugal direction
Slightly expand.
Device 1 further includes housing 14：Housing 14 has the overall shape of the pipe in both ends open.Housing 14 is received and held
Device 2 and piston rod 9.As will hereinafter appear, container 2 is fixed in injection stage relative to housing 14.Container 2 can be
By any connection or fixed mechanism in injection stage（Such as clip, the co-acting part being engaged with each other）It is fixed on housing 14.
These couple and/or fixed mechanism is described in WO2007/132353 and here is not repeated.
Housing 14 includes inner barrel 15 in its proximal region, and the inner barrel is provided with the edge to form distal abutment surface 17
16。
The device of Fig. 1-3 further includes bias mechanism, and the bias mechanism is used for piston rod 9 in injection from trend
Distally promotes.In the illustrated example, the bias mechanism is that occur in the form of the helical spring 18 around the positioning of piston rod 9.
The proximal end of helical spring 18 is pressed on the distal abutment surface 17 of the edge 16 of the inner barrel 15 of housing 14, and the spiral bullet
The distal end portion of spring 18 is pressed in the proximal face of proximal flange 11 of piston rod 9.
In use front position as shown in Figure 1, helical spring 18 is in compression position and the neck ring 12 of piston rod 9
Outward flange 12a is pressed in the teeth portion of two deflections on the inner barrel 15 for being positioned at housing 14（Do not show）Proximal abutment surface
On.
As in the embodiment disclosed in figs. 1-3, device 1 further includes the push button 19 for activation injection.In the enforcement for showing
In example, push button 19 is positioned in the proximal region of housing 14 and can put in user the proximal-lateral wall of the push button 19
Pressure effect lower edge distal direction on 19a is slightly moved.For this purpose, push button 19 is on the inner surface of its proximal-lateral wall 19a
It is provided with two teeth portion 20 extended along distal direction.In activation injection, the two teeth portion 20 will be contacted and be pressed with piston thereon
The teeth portion of two deflections of the inner barrel 15 of the outward flange 12a of bar 9（Do not show）And the teeth portion of the two deflections is deflected, from
And the piston rod 9 is discharged from the inner barrel 15.Then, push button 19 is used as the triggering device of injection.
Push button 19 is further provided with longitudinal rod 21, and the longitudinal rod has free distal end portion 21b and is attached to push button 19
Horizontal proximal wall 19a inner surface on proximal end 21a.Hollow cylinder 10 of the overall diameter of longitudinal rod 21 less than piston rod 9
Interior diameter.Longitudinal rod 21 is spaced apart relative to the proximad of piston rod 9 and its distal end portion 21b is slidingly received in piston rod
In 9 hollow cylinder 10, as shown in Figure 1.
The distal end portion 21b of longitudinal rod 21 is provided with projection 22, and the projection has less than the interior diameter of hollow cylinder 10 still
More than the overall diameter of the interior diameter of neck ring 12.
The operation of the device of Fig. 1-3 will now be described.
User possesses as shown in Figure 1 in the device 1 using front position.In this position, as previously mentioned
, helical spring 18 is in compression position.Equally in this position, longitudinal rod 21 is accepted in the hollow cylinder of piston rod 9
In 10.
When user determines that carrying out product injects, user is placed in device 1 on injection site 7 and by push button
Apply pressure distad in 19 horizontal proximal wall 19a so as to trigger injection.Thus make push button 19 relative to housing 14 to remote
Lateral movement, and as has already been mentioned above, thus teeth portion 20 discharges helical spring 18 from the release plunger bar 9 of inner barrel 15, makes
It is distad stretched so as to return to its natural extended position.It is this for discharging bias mechanism（Such as spiral of apparatus of the present invention 1
Spring 18）Activation step be described in WO2007/132353.
Because helical spring 18 stretches along distal direction, the helical spring is pressed on the flange 11 of piston rod 9 by it
Distal end portion and distad promote piston rod 9.As the result of its distal motion, piston rod 9 contact with piston 8 and with appearance
Device 2 couples so that pin 5 distad finite motion and is inserted injection site 7 by container 2（As shown in Figure 3）.This inserting step exists
For example in WO2007/132353 it is described.Subsequently, by making the outward flange 2a Jing middle springs 30 of container and being received in shell
The distal region of body 14 is interior and classical mechanisms of the Jing for example described in WO2007/132353 is connected on the housing 14
Needle shield 40 against so that the further distal movement of container 2 is prevented from.As shown in figure 3, the distal end portion of needle shield 40 against
On injection site 7.As a result, the further distal movement of piston rod 9 makes the distal motion of piston 8：Injecting step starts.
Therefore piston rod 9 is attached to piston 8 along distal direction.
During insertion and injecting step, push button 19 is by such as coupling mechanism or fixed mechanism（Do not show）Relative to
Housing 14 keeps fixing.Therefore longitudinal rod 21 is fixed in injection process relative to the housing.As a result, when piston rod 9 to
When distally motion is inserted with injecting step so as to realize, longitudinal rod 21 is set to slide relative to the hollow cylinder 10 of the piston rod 9.
The relative position closed to an end between secondary piston bar 9 and longitudinal rod 21 in injection is shown on Fig. 2.As being somebody's turn to do
What figure clearly showed, the wall 13 of the neck ring 12 of the projection 22 of the distal end portion 21b of longitudinal rod 21 and the hollow cylinder 10 of piston rod 9
Inner surface contact.The wall 13 of neck ring 12 is that overall diameter can radially bend and projection 22 is interior straight more than neck ring 12
Footpath so that the wall 13 of the neck ring 12 is radially outward deflected：In other words, putting on as the projection 22 against surface
In the presence of stress on the inner surface of the wall 13 of neck ring 12, the interior diameter for making neck ring 12 slightly expands.
Fig. 3 show when piston rod 9 further distal motion and at the end of injection just the neck ring 12 of piston rod 9 with
Relative position between the projection 22 of longitudinal rod 21.In the presence of the active force of helical spring 18, projection 22 departs from has returned
To the neck ring 12 of its free position.Friction of the projection 22 on the wall 13 of neck ring 12 when the projection departs from the neck ring 12 is produced
Sound is born, indicates that the sound that injection is completed is indicated as user.As seen in Figure 3, the close container 2 of present piston 8 is remote
Side and product is substantially completely discharged from container 2.
In this example, the wall 13 of neck ring 12 is used as the element of the first deflection being positioned on piston rod 9 and dashes forward
Play 22 to be used as to be attached to the second element of the housing, first and second element is assisted each other in the presence of bias mechanism 18
Make to be indicated to produce the sound.
Second embodiment of apparatus of the present invention is shown on Fig. 4-6, referred to as device 101, wherein the first deflection
Element be attached to housing.The reference that same parts are represented in Fig. 1-3 has been continued to use on these figures.
The device 101 of Fig. 4-6 includes the piston rod 9 with the shape of hollow cylinder 110, and the hollow cylinder is in its distal end portion
Closed by transverse wall 111.In the embodiment shown in the drawings, bias mechanism is being received in the hollow cylinder 110 of piston rod 109
Helical spring 118 form occur.The distal end portion of helical spring 118 is pressed in the proximal face of the transverse wall 111 of piston rod 109
On, and the proximal end of helical spring 118 is pressed in the inner barrel 15 for being positioned at housing 14 in the similar mode described in Fig. 1-3
On against surface（Do not show）On.
Using front, piston rod 109 by being bonded on nearside recess 112 in the radial projection 116 of inner barrel 15 couple
To housing 14, the nearside recess 112 is arranged in the proximal region of the outer wall of piston rod 109.
The outer wall of piston rod 109 is further provided with distal recess 113, and the distal recess is relative to the nearside recess
112 are distad spaced apart.
Device 101 further includes two deflection longitudinal direction supporting legs 121.Proximal end 121a of deflection longitudinal direction supporting leg 121
It is fixed on housing 14, and the distal end portion 121b of longitudinal supporting leg 121 is free.As shown in figure 4, using front position
In, the free distal end portion 121b of deflection longitudinal direction supporting leg 121 is resisted against in the distal recess 113 of the outer wall of piston rod 109.At this
In position, deflection longitudinal direction supporting leg 121 is in their free position, and the inwall of each deflection longitudinal direction supporting leg 121
122 it is parallel with the distally longitudinal wall 117 of the inner barrel 15 of housing 14 and with its soft contact, as indicated on fig. 4.
In order to be injected, user pushes push button 19 so as to release plunger in the identical mode as described by Fig. 1-3
Bar 109.What the embodiment such as Fig. 1-3 had been described above, the distal movement of piston rod 109 makes pin 5 insert and inject.
As it was previously stated, in injection process, push button 19 is fixed relative to housing 14.
In injection stage, piston rod 109 slides relative to deflection longitudinal direction supporting leg 121, deflection longitudinal direction supporting leg
Fix relative to housing 14.As a result, the change of the external diameter of hollow cylinder 110 due to piston rod 109, deflection longitudinal direction supporting leg
121 distal end portion 121b departs from distal recess 113, and therefore make the deflection supporting leg the deflection of distal end portion outward radial,
As shown in Figure 5.Therefore, the outer wall of piston rod 109 is applied and is stressed on the supporting leg 121 of deflection longitudinal direction.As shown in the figure,
In this depressed position of deflection longitudinal direction supporting leg 121, the inwall 122 of deflection longitudinal direction supporting leg 121 no longer with inner barrel
15 distally longitudinal wall 117 is contacted.
As shown in fig. 6, when piston 8 reaches the distal end portion of container 2, work of the piston rod 109 in the helical spring 118 for stretching
It is firmly lower to depart from deflection longitudinal direction supporting leg 121.The outer wall of piston rod 109 is no longer applied and is stressed in deflection longitudinal direction supporting leg
On 121 distal end portion 121b, and deflection longitudinal direction supporting leg 121 returns to their free position, as shown in Figure 6.By returning
To their free position, deflection longitudinal direction supporting leg 121, particularly the inner barrel is collided via their distal end portion 121b
Distally longitudinal wall 117, so as to producing sound and informing that user's injection is completed.The distally longitudinal wall 117 of the inner barrel is made
It is for the contact surface of deflection longitudinal direction supporting leg, the distally longitudinal wall of the inner barrel and institute in the contact surface
State deflection longitudinal direction supporting leg and produce sound.
Element and the second element association of the first deflection of the 3rd embodiment of apparatus of the present invention is shown on Fig. 7-8
The partial sectional view of work.
The device 201 of Fig. 7-8 includes piston rod 209, and the piston rod includes hollow cylinder 210, and the hollow cylinder exists
Its distal end portion closes and receives wherein the helical spring 218 as bias mechanism by transverse wall 211.Piston rod 209 is at it
Prop up the longitudinal direction of the deflection for nearside recess 212 being provided with outer wall and being distad spaced apart relative to the nearside recess 212
Leg 213.The distal end portion 213b of longitudinal supporting leg 213 of the deflection is fixed to the outer wall of piston rod 209 and its proximal end 213a
It is free.Device 201 further includes housing 214, and the housing includes longitudinal projection 215 on its inwall.Housing 214
Inwall be further provided with the radial teeth 216 being spaced apart with the proximad of longitudinal projection 215 and with longitudinal projection 215
Contact surface 214a being distad spaced apart.
As shown in fig. 7, in device 201 uses front position, proximal end 213a of longitudinal tongue 213 of deflection against
In longitudinal projection 215 of housing 214, and radial teeth 216 is engaged in the nearside recess 212 of the outer wall of piston rod 209.
In triggering injection, radial teeth 216 is disengaged with nearside recess 212（Step does not show）, and piston rod
209 discharge and and distal motion in the presence of the helical spring 218 being released.As shown in figure 8, in injection stage,
Longitudinal projections of the distal end portion 213a of longitudinal tongue 213 of the distal motion of piston rod 209 and deflection relative to housing 214
215 distad slide.In the step process, longitudinal projection 215 is applied and is stressed in the vertical of deflection in its depressed position
To on tongue 213.
As shown in figure 9, at the end of injection, the distal end portion 213a of longitudinal tongue 213 of deflection reaches the remote of projection 215
Side and depart from longitudinal projection 215, return to its not subjected to pressure position.By returning to its not subjected to pressure position, deflection
The distal end portion 213a of longitudinal tongue 213 collides contact surface 214a of the inwall of housing 214, informs that user notes so as to produce sound
Shoot away into.
The 4th embodiment of apparatus of the present invention is partially show on Figure 10 a and 10b, wherein the first element is easily broken
Split.The device 301 of Figure 10 a and 10b includes piston rod 309, and wire rod 321 is fixed with proximal end 309a of the piston rod
Distal end portion 321b.Proximal end 321a of wire rod 321 is fixed on the fixing point 320 of the transverse wall 319a of push button 319, the push button
The housing is attached in injection stage（Do not show）.Therefore, fixing point 320 be positioned in the proximal region of housing 14 and
Fix relative to the housing 14 in injection process.Wire rod 321 is flexible and in device 301 in using front position
When can itself fold, as shown in Figure 10 a.
When the position that device 301 terminates in its injection, the length of wire rod 321 is less than fixing point 320 and piston rod
The separate distance of 309 proximal end 309a.As a result, working as piston（Do not show）Reach container（Do not show）Distal end portion when, line
Material 321 launches until in the helical spring that piston rod 309 is pulled along distal direction（Do not show）Active force under rupture, such as scheme
Shown in 10b.
As shown in Figure 10 a, when wire rod 321 ruptures, it produces sound so as to inform that user's injection is completed.
Wire rod 321 can be made up of any material that can be ruptured under stress.For example, wire rod 321 can be by Buddhist nun
But the material of dragon, polypropylene or other rigid or semi-rigid easy fractures is made.
Figure 11 partially show the 5th embodiment of apparatus of the present invention, and wherein the wire rod of Figure 10 a and 10b is by rigid cable
Rope 421 replaces.Proximal end 421a of rigid cable 421 is fixed on the fixing point 420 being positioned on push button 419, in injection rank
During section, the button 419 is attached to housing（Do not show）.Rigid cable 421 is allowed in the hollow cylinder of piston rod 409
Slide in 410.
The distal end portion 421b of rigid cable 421 is provided with projection 422, and the overall diameter of the projection is interior more than neck ring 412
Diameter, the neck ring is arranged at proximal end 409a of hollow cylinder 410 of piston rod 409.The wall of neck ring 412 is not deflection
And neck ring 412 interior diameter not under stress expand.
The length of rigid cable 421 is less than the distance for separating fixing point 420 with neck ring 412.
During injection stage, it is allowed to which projection 422 is slided until described in the hollow cylinder 410 of piston rod 409
Projection is contacted before injection just will terminate with neck ring 412.
It is not allowed to depart from from the neck ring 412 when projection 422 is contacted with the neck ring, and the neck ring 412
Wall is not deflection.As a result, effect of the rigid cable in the helical spring 418 for making the distal motion of piston rod 309
Rupture at the end of injection under power, so as to producing sound and informing that user's injection is completed.
Rigid cable 421 can be made up of any material that can be ruptured under stress.For example, rigid cable 421 is by gathering
The material of propylene or other easy fractures is made.
The device of the present invention allows user clearly to be informed that injection is completed.This is particularly weighed in self-injection device
Will, in the self-injection device, it is injected through automatics（Such as bias mechanism）To realize, user does not have shadow to it
Ring.If user is usually the patient of uncomfortable use injection device, it is important that user will be apprised of injection and terminate simultaneously
And the time that product is substantially completely discharged, so as to user can safely extract injection device from injection site.
Claims (4)
1. one kind is used to that product (6) automatic injection to be entered the device (1) of injection site (7), and the product is taken by container (2)
Band, the container has the proximal end (3) of opening and carries the substantially closed distal end portion (4) and piston of pin (5)
(8), to provide outlet from the product of the container, the piston is arranged in the container and can be relative the pin
In the container distal motion, the piston distal movement makes the product arrange from the container by the pin
Go out, so as to realize the injection of the product, described device (1) includes：
- piston rod (409), the piston rod is used for being attached to the piston (8) along distal direction in injection process,
- bias mechanism (418), the bias mechanism is used to that the piston rod (409) to be made in injection process relative to the appearance
Device (2) distal motion,
- housing (14；214), the housing design be used for receive the container (2), the piston rod (409) at least in part with
And the bias mechanism (418),
- controlling organization (409,421), the controlling organization is designed for when the piston (8) is in the described remote of the container (2)
The sound is produced when side (4) is nearby and the product (6) is substantially completely discharged from the container to indicate, so as to make
User provides the instruction that the product injection is completed,
Described device (1) is characterised by：
The controlling organization includes at least one first elements (421),
First element includes easy fracture part (421), and the easy fracture part is described with being directly or indirectly attached to
The proximal end (421a) of housing, the easy fracture part ruptures in the presence of the bias mechanism at the end of injection, so as to
Produce the sound to indicate, and
The piston rod (409) includes hollow cylinder (410), and the hollow cylinder sets in the proximal end (409a) of the hollow cylinder
Neck ring (412) is equipped with, the piston rod (409) is configured to receive a part for the easy fracture part (421).
2. device (1) as claimed in claim 1, it is characterised in that the easy fracture part is included with proximal end (421a)
With the rigid cable (421) of distal end portion (421b), the proximal end (421a) of the rigid cable (421) be fixed to be positioned at it is described
Fixing point (420) in the proximal region of housing, the fixing point described in injection process (420) is fixed relative to the housing,
And the distal end portion (421b) of the rigid cable (421) is slidingly received in the hollow cylinder (410), the rigidity
The distal end portion (421b) of cable (421) is provided with projection (422), and the projection has straight more than in the neck ring (412)
The overall diameter in footpath, the length of the rigid cable (421) is less than the neck ring of the piston rod (409) at the end of injection
(412) and the separate distance of the fixing point (420), the piston rod (409) in the presence of the bias mechanism distad
Motion make the rigid cable (421) rupture at the end of injection.
3. device (1) as claimed in claim 2, it is characterised in that the rigid cable (421) is made up of polypropylene.
4. device (1) as described in any one of claim 1 to 2, it is characterised in that first element (421) and institute
State bias mechanism (418) different.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410161876.4A CN103920212B (en) | 2008-09-29 | 2008-09-29 | Automatic injecting device capable of giving sound indication when injection is completed |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410161876.4A CN103920212B (en) | 2008-09-29 | 2008-09-29 | Automatic injecting device capable of giving sound indication when injection is completed |
| CN200880131863.5A CN102209563B (en) | 2008-09-29 | 2008-09-29 | Automatic injection device with audible indicator of completed injection |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200880131863.5A Division CN102209563B (en) | 2008-09-29 | 2008-09-29 | Automatic injection device with audible indicator of completed injection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103920212A CN103920212A (en) | 2014-07-16 |
| CN103920212B true CN103920212B (en) | 2017-04-12 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410161876.4A Active CN103920212B (en) | 2008-09-29 | 2008-09-29 | Automatic injecting device capable of giving sound indication when injection is completed |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103920212B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018041741A1 (en) | 2016-08-30 | 2018-03-08 | Sanofi-Aventis Deutschland Gmbh | Injection device |
| CN111282094B (en) * | 2020-03-05 | 2020-11-10 | 苏州恒瑞宏远医疗科技有限公司 | Automatic injection device and method of use |
| CN111463614B (en) * | 2020-03-05 | 2021-05-18 | 苏州恒瑞宏远医疗科技有限公司 | Mechanical transmission device |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004052219A1 (en) * | 2004-10-27 | 2006-05-04 | Tecpharma Licensing Ag | Injection devices for delivering insulin with restrictor, comprises prestressed spring washer, bi/multi stable signal generating burst/place element and releasing element that emits signal with deformation |
| DE102007013838A1 (en) * | 2007-03-22 | 2008-09-25 | Tecpharma Licensing Ag | Injection device with time-constant Ausschüttsignal |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE376437T1 (en) * | 2004-01-23 | 2007-11-15 | Medical House Plc | INJECTION DEVICE |
| FR2899482A1 (en) * | 2006-04-11 | 2007-10-12 | Becton Dickinson France Soc Pa | Automatic medicament/product injection device for patient, has safety shield coupled to housing, and provided in active state at end of needle insertion step before which product/medicament injection step is not started |
-
2008
- 2008-09-29 CN CN201410161876.4A patent/CN103920212B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004052219A1 (en) * | 2004-10-27 | 2006-05-04 | Tecpharma Licensing Ag | Injection devices for delivering insulin with restrictor, comprises prestressed spring washer, bi/multi stable signal generating burst/place element and releasing element that emits signal with deformation |
| DE102007013838A1 (en) * | 2007-03-22 | 2008-09-25 | Tecpharma Licensing Ag | Injection device with time-constant Ausschüttsignal |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103920212A (en) | 2014-07-16 |
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