CN103920212A - Automatic injecting device capable of giving sound indication when injection is completed - Google Patents
Automatic injecting device capable of giving sound indication when injection is completed Download PDFInfo
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- CN103920212A CN103920212A CN201410161876.4A CN201410161876A CN103920212A CN 103920212 A CN103920212 A CN 103920212A CN 201410161876 A CN201410161876 A CN 201410161876A CN 103920212 A CN103920212 A CN 103920212A
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- piston rod
- injection
- container
- housing
- end portion
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Abstract
The invention relates to an automatic injecting device (1) capable of giving sound indication when injection is completed. The device comprises a container (2), a piston (8), a piston rod (9), a bias pressure mechanism (18), a shell (14) and control mechanisms (13 and 22), wherein the piston rod (9) is connected to the piston (8) in the injecting process, the bias pressure mechanism (18) is used for making the piston rod (9) move to the far side relative to the container (2), the container (2), the piston rod (9) and the bias pressure mechanism (18) are contained in the shell (14), and the control mechanisms (13 and 22) are used for generating sound indication when injection is completed. The device is characterized in that each control mechanism comprises a first element (13) and a second element (22), each first element is flexible or prone to fracture and connected to the shell (14) or the piston rod (9) in the injecting process, each second element is connected to the piston rod (9) or the shell (14) in the injecting process, and the first elements and the second elements cooperate with each other to give sounding indication under the action of the bias pressure mechanism (18) when the injection is completed.
Description
The application is that to be called " with the automated injection device that completes injection sound indication ", international filing date be that JIUYUE in 2008 29 days, international application no are that PCT/IB2008/003285, national applications number are dividing an application of 200880131863.5 application for a patent for invention to name.
Technical field
The present invention relates to a kind of device for automatic injection product, described device guarantees that user is by product fully injection substantially.
Background technology
In this application, the distal end portion of assembly or device is appreciated that as referring between the correct operating period the end away from user hands, and proximal end is appreciated that as referring to the end of the most close user hands between the correct operating period.Similarly, in this application, " distal direction " is for limiting injection direction, and " proximal direction " is for limiting the direction contrary with injection direction.
It is essential that some disease makes regularly (for example,, on the basis of every day) injectable drug or product become.In order to simplify the treatment of these diseases, developed some device for automatic injection to allow patient oneself to inject.
Certainly, because patient is conventionally neither nurse neither be educated people aspect medical device, this device for automatic injection must verifiedly be use very simple and very safe.Especially, importantly guarantee to utilize such device to inject the product of controlled dose, that is to say, must inject completely.And in some cases, user can be extracted the device for automatic injection before injection completes.Therefore fully injection and user can be from injection site extracting apparatus substantially, concerning user, to be importantly apprised of product.
Known a kind of automated injection device from patent application WO2007/132353, wherein sound sends in whole injection process, thereby when sound stops, indicating patient infusion to complete.
Need to there is the self-injection device that can clearly indicate user to inject.
Summary of the invention
The present invention meets the need by proposing the alternative of said apparatus.The present invention proposes a kind of for product automatic injection being injected to the device of injection site, and described device produces sound indication when injection completes.
The present invention relates to a kind of for product automatic injection being injected to the device of injection site, described product is carried by container, described container has open proximal end and carries distal end portion and the piston of closure substantially of pin, described pin provides outlet for the described product from described container, described piston is arranged in described container and can be with respect to described container distal motion, the motion distad of described piston makes described product discharge from described container by described pin, thereby realize the injection of described product, described device comprises:
-piston rod, described piston rod is used for along distal direction, being attached to described piston at injection process,
-bias mechanism, described bias mechanism is used for making described piston rod with respect to described container distal motion at injection process,
-housing, described housing design is used for receiving at least in part described container, described piston rod and described bias mechanism,
-controlling organization, described controlling organization is designed near described piston is arranged in the described distal end portion of described container and described product produces sound indication when described container is fully discharged substantially, thereby the indication that provides described product to inject for user
Described device is characterised in that:
Described controlling organization comprises at least one first element and at least one the second element, described the first element is flexible or easy fracture and in injection process, is attached to directly or indirectly described housing or described piston rod, described the second element is attached to directly or indirectly described piston rod or described housing in injection process, and described the first and second elements cooperate each other to produce described sound indication under the effect of described bias mechanism when injection finishes.
Device of the present invention allows user clearly to be informed and injected.
In this application, by statement " A is attached to B along directions X ", meant when A is moved along directions X, A is attached to B.In other words, if A is moved along directions X, so also make B along directions X, move under the pulling of A.
In this application, by statement " A is attached to B directly or indirectly ", meant by A is directly attached to B, or A is attached to B(indirectly connects by linking the intermediate member of A to B) make A and B relative to each other fixing.
In one embodiment of the invention, described the first element is different from described bias mechanism.
In one embodiment of the invention, described the first element comprises at least one parts of deflection radially that can deflect into free position from depressed position, the parts of described radially deflection are producing sound when its depressed position moves on to its free position, described the second element comprises at least one abutment surface, described abutment surface on the parts of described radially deflection stress application to the parts of described radially deflection are placed in to its depressed position before injection finishes, and make described abutment surface under the effect of described bias mechanism, when injection finishes, discharge described stress.
For instance, when injection finishes, by bias mechanism, be applied under the parts or the active force on abutment surface of radially deflection, the parts of described radially deflection depart from described abutment surface, or the parts of deflection radially described in described abutment surface departs from, described parts produce sound to the frictional force on described surface.In an embodiment, can produce additional sound, thereby the parts for example by described radially deflection collide contact surface when turning back to its free position, produce additional sound.
In one embodiment of the invention, described piston rod comprises hollow cylinder, described hollow cylinder is provided with neck ring in its proximal end, the wall of described neck ring can outward radial deflection, and described device is further included in longitudinal rod fixing with respect to described housing in injection process, described longitudinal rod is spaced apart with respect to described piston rod proximad, the distal end portion of described longitudinal rod is received in slidably in described hollow cylinder and is provided with projection, described projection has the overall diameter of the interior diameter that is greater than described neck ring, the parts of described radially deflection comprise that the described wall of described neck ring and described abutment surface comprise described projection, described projection before injection finishes on the wall of described neck ring stress application, and by depart from described neck ring under the effect of described bias mechanism, when finishing, injection discharges described stress.
In such a embodiment, when described projection departs from described neck ring under the active force being applied by described bias mechanism, the friction of described projection in described neck ring produces sound.Therefore, user is apprised of and has been injected.
In another embodiment of the present invention, the parts of described radially deflection comprise the longitudinal supporting leg of at least one deflection, the longitudinal supporting leg of this deflection has and is fixed to the proximal end of described housing and free distal end portion, described abutment surface comprises the outer wall of described piston rod, the described outer wall of described piston rod contact the distal end portion of the longitudinal supporting leg of described deflection and before injection finishes stress application in the distal end portion of the longitudinal supporting leg of described deflection to deflected into its depressed position, the described outer wall of described piston rod discharges described stress by depart from the longitudinal supporting leg of described deflection under the effect of described bias mechanism when injection finishes.
In another embodiment of the present invention, the parts of described radially deflection comprise the longitudinal supporting leg of at least one deflection, the longitudinal supporting leg of described deflection has the distal end portion on the outer wall that is fixed on described piston rod, described abutment surface comprises longitudinal projection of described inner walls, described longitudinal projection contact the proximal end of the longitudinal supporting leg of described deflection and before injection finishes stress application in the proximal end of the longitudinal supporting leg of described deflection to deflected into its depressed position, described longitudinal projection discharges described stress by depart from the longitudinal supporting leg of described deflection under the effect of described bias mechanism when injection finishes.
Device of the present invention may further include the contact surface on the inwall that is positioned described housing, thereby the longitudinal supporting leg of described deflection collides described contact surface when turning back to its free position, produces sound.
In another embodiment of the present invention, described the first element comprises easy fracture parts, described easy fracture parts have the proximal end that is attached to directly or indirectly described housing, and the distal end portion that is attached to directly or indirectly described piston rod, thereby make described easy fracture parts when injection finishes, rupture and produce sound under the effect of described bias mechanism.
In one embodiment of the invention, described easy fracture parts comprise the flexible wire rod with proximal end and distal end portion, the proximal end of described flexible wire rod is fixed to the fixing point being positioned in described housing proximal region, at fixing point described in injection process, with respect to described housing, fix, and the distal end portion of described flexible wire rod is fixed to the proximal end of described piston rod, the length of described flexible wire rod is less than when injection finishes the distance that the described proximal end of described piston rod and described fixing point are separated, the motion distad under the effect of described bias mechanism of described piston rod makes the fracture when injection finishes of described flexible wire rod.For example, but described wire rod can be made by the material of rigidity or semi-rigid easy fracture.In one embodiment, described wire rod is made by nylon or polypropylene.
In another embodiment of the present invention, described piston rod comprises hollow cylinder, described hollow cylinder is provided with neck ring in its proximal end, described easy fracture parts comprise the rigidity cable with proximal end and distal end portion, the proximal end of described rigidity cable is fixed to the fixing point being positioned in described housing proximal region, described fixing point is fixed with respect to described housing in injection process, and the distal end portion of described rigidity cable is received in described hollow cylinder slidably, the described distal end portion of described rigidity cable is provided with projection, described projection has the overall diameter of the interior diameter that is greater than described neck ring, the length of described rigidity cable is less than when injection finishes the distance that the described neck ring of described piston rod and described fixing point are separated, described piston rod distal motion under the effect of described bias mechanism makes the fracture when injection finishes of described rigidity cable.For example, described rigidity cable can be made by easy fracture material.In one embodiment, described rigidity cable is made by polypropylene.
Accompanying drawing explanation
Referring now to description and accompanying drawing below, device of the present invention is described further, in the accompanying drawings:
Fig. 1 is the longitudinal sectional view before use of first embodiment of apparatus of the present invention;
Fig. 2 is the partial sectional view of the device of Fig. 1, shows the position of controlling organization before injection finishes;
Fig. 3 is the device of Fig. 1 longitudinal sectional view when injection finishes;
Fig. 4 is the longitudinal sectional view before use of second embodiment of apparatus of the present invention;
Fig. 5 is the partial sectional view of the device of Fig. 4, shows the position of controlling organization before injection finishes;
Fig. 6 is the device of Fig. 4 longitudinal sectional view when injection finishes;
Fig. 7-9th, the controlling organization of the 3rd embodiment of apparatus of the present invention is respectively in the injection process before use, before injection finishes, and the partial sectional view when injection finishes;
Figure 10 a and 10b are that the controlling organization of the 4th embodiment of apparatus of the present invention is distinguished before use and the partial sectional view when injection finishes;
Figure 11 is the partial sectional view in the injection process of the 5th embodiment before injection finishes of apparatus of the present invention.
Specific embodiment
With reference now to accompanying drawing,, will describe the present invention in detail.Fig. 1 shows according to the longitudinal sectional view of first embodiment of the device for automatic injection of the present invention, state when this timer is in and offers user before use, and be referred to as in the following description device 1.Device 1 comprises container 2, and described container has nearside open end 3, with the closed distal end portion 4 substantially of pin 5; Container 2 carries the product 6 that will be injected into injection site 7.Container 2 is provided with outward flange 2a in its proximal end.Piston 8 is arranged in container 2 and can moves with respect to described container 2.As occurred hereinafter, piston 8 will make product 6 discharge from container 2 along moving of distal direction.Device 1 also comprises piston rod 9: as occurred hereinafter, piston rod 9 will be attached to piston 8 along distal direction in injection process.
In the example shown in Fig. 1-3, piston rod 9 comprises hollow cylinder 10, and described hollow cylinder has flange 11 and has neck ring 12 in its proximal end at its distal end portion, and the interior diameter of described neck ring 12 is less than the interior diameter of described hollow cylinder 10.Neck ring 12 is provided with outward flange 12a in its proximal end.The wall 13 of neck ring 12 can outward radial deflection, that is to say, the interior diameter of neck ring 12 can expand along centrifugal direction under the stress on around slightly at the inner surface of wall 13 that puts on described neck ring 12.
Device 1 further comprises housing 14: housing 14 has the overall shape at the pipe of both ends open.Housing 14 is received container 2 and piston rod 9.As occurred hereinafter, container 2 is fixing with respect to housing 14 in injection stage.Container 2 can be in injection stage for example, be fixed on housing 14 by any connection or fixed mechanism (clip, the co-acting part that is engaged with each other).These connections and/or fixed mechanism are described and no longer repeat at this in WO2007/132353.
Housing 14 comprises inner barrel 15 in its proximal region, and described inner barrel is provided with the edge 16 that forms distally abutment surface 17.
The device of Fig. 1-3 further comprises bias mechanism, and described bias mechanism for automatically distad promoting piston rod 9 when injecting.In the example showing, this bias mechanism is the form appearance with the helical spring 18 around piston rod 9 location.The proximal end of helical spring 18 is pressed on the distally abutment surface 17 of edge 16 of inner barrel 15 of housing 14, and the distal end portion of described helical spring 18 is pressed in the proximal face of proximal flange 11 of piston rod 9.
In use front position as shown in Figure 1, the outward flange 12a of the neck ring 12 of helical spring 18 in compression position and piston rod 9 is pressed on the nearside abutment surface of tooth portion (not shown) of two deflections on the inner barrel 15 that is positioned at housing 14.
Embodiment as Figure 1-3, device 1 further comprises for activating the push button 19 of injection.In the embodiment showing, push button 19 is positioned in the proximal region of housing 14 and can puts under the pressure-acting on the proximal-lateral wall 19a of described push button 19 and move slightly along distal direction at user.For this reason, push button 19 is provided with two tooth portions 20 of extending along distal direction on the inner surface of its proximal-lateral wall 19a.When activating injection, these two tooth portions 20 will contact the tooth portion (not shown) of two deflections and the tooth portion of these two deflections of deflection of the inner barrel 15 that is pressed with piston rod 9 outward flange 12a on it, thereby described piston rod 9 is discharged from described inner barrel 15.Then, push button 19 is as the flip flop equipment of injection.
Push button 19 is further provided with longitudinal rod 21, and described longitudinal rod has free distal end portion 21b and is attached to the proximal end 21a on the inner surface of horizontal proximal wall 19a of push button 19.The overall diameter of longitudinal rod 21 is less than the interior diameter of the hollow cylinder 10 of piston rod 9.With respect to piston rod 9 proximads, spaced apart and its distal end portion 21b is received in the hollow cylinder 10 of piston rod 9, as shown in Figure 1 longitudinal rod 21 slidably.
The distal end portion 21b of longitudinal rod 21 is provided with projection 22, and but described projection has and is less than hollow cylinder 10 interior diameters is greater than the overall diameter of neck ring 12 interior diameters.
To the operation of the device of Fig. 1-3 be described now.
User has the device 1 in use front position as shown in Figure 1.In this position, as previously mentioned, helical spring 18 is in compression position.In this position, longitudinal rod 21 is accepted in the hollow cylinder 10 of piston rod 9 equally.
When user determines to carry out product injection, thereby user is placed in device 1 on injection site 7 and by the pressure distad applying on the horizontal proximal wall 19a of push button 19 and triggers injection.Make thus push button 19 with respect to housing 14 distal motion, and as has already been mentioned above, and tooth portion 20, from inner barrel 15 release plunger bars 9, discharges helical spring 18 thus, thereby it is distad stretched, gets back to its natural extended position.Thisly for example, for discharging the activation step of bias mechanism (helical spring 18 of apparatus of the present invention 1), at WO2007/132353, be described.
Because helical spring 18 stretches along distal direction, described helical spring is pressed in the distal end portion on the flange 11 of piston rod 9 and is distad promoted piston rod 9 by it.As the result of its distal motion, piston rod 9 contacts with piston 8 and connects with container 2, make container 2 distad finite motion and pin 5 is inserted to injection site 7(as shown in Figure 3).This inserting step is for example being described in WO2007/132353.Subsequently, outward flange 2a by making container through middle springs 30 be received in classical mechanism in the distal region of housing 14 and through for example describing in WO2007/132353 be connected to needle shield 40 on described housing 14 against, make container 2 further motion be distad prevented from.As shown in Figure 3, the distal end portion of needle shield 40 is resisted against on injection site 7.Result is, piston rod 9 further motion distad makes piston 8 distal motion: injecting step starts.Therefore piston rod 9 is attached to piston 8 along distal direction.
In insertion and injecting step process, push button 19 keeps fixing by for example coupling mechanism or fixed mechanism (not shown) with respect to housing 14.Therefore longitudinal rod 21 is fixed with respect to described housing in injection process.Result is, thereby when piston rod 9 distal motion realize insertion and injecting step, longitudinal rod 21 is slided with respect to the hollow cylinder 10 of described piston rod 9.
On Fig. 2, shown at injection close to an end secondary piston bar 9 and longitudinal rod 21 relative position each other.As the clear demonstration of this figure, the projection 22 of the distal end portion 21b of longitudinal rod 21 contacts with the inner surface of the wall 13 of the neck ring 12 of the hollow cylinder 10 of piston rod 9.The wall 13 of neck ring 12 is interior diameters that overall diameter radially deflection and projection 22 is greater than neck ring 12, make the radially outward deflection of described wall 13 of described neck ring 12: in other words, in the projection 22 as abutment surface, put under the effect of the stress on the inner surface of wall 13 of neck ring 12, the interior diameter of neck ring 12 is expanded slightly.
Fig. 3 shows when piston rod 9 relative position between the neck ring 12 of piston rod 9 and the projection 22 of longitudinal rod 21 when further distal motion injecting has just finished.Under the effect of the active force of helical spring 18, projection 22 departs from the neck ring 12 of having got back to its free position.When described projection departs from described neck ring 12, the friction of projection 22 on the wall 13 of neck ring 12 produces sound, as the sound indication of having injected for user indication.As seen in Figure 3, now piston 8 approaches container 2 distal end portion and product are fully discharged substantially from container 2.
In this example, the wall 13 of neck ring 12 is used as the element and the projection 22 that are positioned the first deflection on piston rod 9 the second element that is attached to described housing, and described the first and second elements cooperate each other to produce sound indication under the effect of bias mechanism 18.
Second embodiment that has shown apparatus of the present invention on Fig. 4-6, is referred to as device 101, and wherein the element of the first deflection is attached to housing.On these figure, continued to use the Reference numeral that represents same parts in Fig. 1-3.
The device 101 of Fig. 4-6 comprises the piston rod 9 with hollow cylinder 110 shapes, described hollow cylinder at its distal end portion by transverse wall 111 closures.In the embodiment of these accompanying drawings, bias mechanism occurs to be received in the form of the helical spring 118 in the hollow cylinder 110 of piston rod 109.The distal end portion of helical spring 118 is pressed in the proximal face of transverse wall 111 of piston rod 109, and the proximal end of helical spring 118 is pressed in the abutment surface (not shown) on the inner barrel 15 that is positioned housing 14 in the similar mode of describing in Fig. 1-3.
Before use, piston rod 109 is attached to housing 14 by being bonded on the radial projection 116 of the inner barrel 15 in nearside recess 112, and described nearside recess 112 is arranged in the proximal region of piston rod 109 outer walls.
The outer wall of piston rod 109 is further provided with distal recess 113, and described distal recess is distad spaced apart with respect to described nearside recess 112.
Device 101 further comprises two longitudinal supporting legs 121 of deflection.The proximal end 121a of the longitudinal supporting leg 121 of deflection is fixed on housing 14, and the distal end portion 121b of described longitudinal supporting leg 121 is freely.As shown in Figure 4, in position, the free distal end portion 121b of the longitudinal supporting leg 121 of deflection is resisted against in the distal recess 113 of piston rod 109 outer walls before use.In this position, the free position of the longitudinal supporting leg 121 of deflection in them, and the longitudinal wall 117 in distally of the inwall 122 of the longitudinal supporting leg 121 of each deflection and the inner barrel 15 of housing 14 is parallel and with its soft contact, as shown on Fig. 4.
In order to inject, user pushes push button 19 so that release plunger bar 109 in identical mode as described in Fig. 1-3.As the embodiment of Fig. 1-3 has described, piston rod 109 motion is distad inserted and injection pin 5.
As previously mentioned, in injection process, push button 19 is fixing with respect to housing 14.
In injection stage, piston rod 109 slides with respect to the longitudinal supporting leg 121 of deflection, and the longitudinal supporting leg of described deflection is fixing with respect to housing 14.Result is, due to the change of hollow cylinder 110 external diameters of piston rod 109, the distal end portion 121b of the longitudinal supporting leg 121 of deflection departs from distal recess 113, and therefore makes the distal end portion outward radial deflection of the supporting leg of described deflection, as shown in Figure 5.Therefore, the outer wall stress application of piston rod 109 is on the longitudinal supporting leg 121 of deflection.As shown in this figure, in this depressed position of the longitudinal supporting leg 121 of deflection, the inwall 122 of the longitudinal supporting leg 121 of described deflection no longer contacts with the longitudinal wall 117 in distally of inner barrel 15.
As shown in Figure 6, when piston 8 arrives the distal end portion of container 2, piston rod 109 departs from the longitudinal supporting leg 121 of described deflection under the active force of the helical spring 118 stretching.The outer wall of piston rod 109 no longer stress application is upper in the distal end portion 121b of the longitudinal supporting leg 121 of deflection, and the longitudinal supporting leg 121 of deflection gets back to their free position, as shown in Figure 6.By being back to their free position, the longitudinal supporting leg 121 of deflection, particularly the distal end portion 121b via them collides the longitudinal wall 117 in distally of described inner barrel, thereby produces sound and inform that user injected.The longitudinal wall 117 in distally of described inner barrel, as the contact surface for the longitudinal supporting leg of described deflection, produces sound at the longitudinal wall in the distally of described the above inner barrel of contact surface and the longitudinal supporting leg of described deflection.
On Fig. 7-8, shown the partial sectional view that the element of the first deflection of the 3rd embodiment of apparatus of the present invention cooperates with the second element.
The device 201 of Fig. 7-8 comprises piston rod 209, and described piston rod comprises hollow cylinder 210, and described hollow cylinder is used as the helical spring 218 of bias mechanism by transverse wall 211 closures and receiving therein at its distal end portion.Piston rod 209 is provided with nearside recess 212 and with respect to described nearside recess 212 longitudinal supporting leg 213 of isolated deflection distad on its outer wall.The distal end portion 213b of longitudinal supporting leg 213 of described deflection is fixed to the outer wall of piston rod 209 and its proximal end 213a is freely.Device 201 further comprises housing 214, and described housing comprises longitudinal projection 215 on wall within it.The inwall of housing 214 be further provided with the isolated radial teeth of described longitudinal projection 215 proximad portion 216 and with described longitudinal projection 215 isolated contact surface 214a distad.
As shown in Figure 7, in the position before device 201 is used, the proximal end 213a of longitudinal tongue 213 of deflection is resisted against in longitudinal projection 215 of housing 214, and radial teeth portion 216 is engaged in the nearside recess 212 of piston rod 209 outer walls.
When triggering injection, radial teeth portion 216 is disengaged (step does not show) with nearside recess 212, and piston rod 209 discharges and and distal motion under the effect of d/d helical spring 218.As shown in Figure 8, in injection stage, the distal end portion 213a of longitudinal tongue 213 of piston rod 209 distal motion and deflection distad slides with respect to longitudinal projection 215 of housing 214.In this step process, longitudinally projection 215 stress applications are on longitudinal tongue 213 of the deflection in its depressed position.
As shown in Figure 9, when injection finishes, the distal end portion 213a of longitudinal tongue 213 of deflection arrives the distal end portion of projection 215 and departs from described longitudinal projection 215, gets back to its not subjected to pressure position.By turning back to its not subjected to pressure position, the contact surface 214a of the distal end portion 213a of longitudinal tongue 213 of deflection collision housing 214 inwalls, informs that user injected thereby produce sound.
The 4th embodiment that has partly shown apparatus of the present invention on Figure 10 a and 10b, wherein the first element is easy fracture.The device 301 of Figure 10 a and 10b comprises piston rod 309, is fixed with the distal end portion 321b of wire rod 321 at the proximal end 309a place of described piston rod.The proximal end 321a of wire rod 321 is fixed on the fixing point 320 of push button 319 transverse wall 319a, and described push button is attached to described housing (not shown) in injection stage.Therefore, fixing point 320 is positioned in the proximal region of housing 14 and in injection process fixing with respect to described housing 14.Wire rod 321 is flexible and can self folds when using front position at device 301, as shown in Figure 10 a.
When position that device 301 finishes in its injection, the length of wire rod 321 is less than the distance that the proximal end 309a of fixing point 320 and piston rod 309 is separated.Result is, when piston (not shown) arrives the distal end portion of container (not shown), wire rod 321 launches until rupture under the active force of helical spring (not shown) that pulls piston rod 309 along distal direction, as shown in Figure 10 b.
As shown in Figure 10 a, when wire rod 321 fracture, thereby it produces sound and informs that user injected.
Wire rod 321 can be made by any material that can rupture under stress.For example, but wire rod 321 can be made by the material of nylon, polypropylene or other rigidity or semi-rigid easy fracture.
Figure 11 has partly shown the 5th embodiment of apparatus of the present invention, and wherein the wire rod of Figure 10 a and 10b is replaced by rigidity cable 421.The proximal end 421a of rigidity cable 421 is fixed on the fixing point 420 being positioned on push button 419, and in injection stage process, described button 419 is attached to housing (not shown).Allow rigidity cable 421 in the interior slip of hollow cylinder 410 of piston rod 409.
The distal end portion 421b of rigidity cable 421 is provided with projection 422, and the overall diameter of described projection is greater than the interior diameter of neck ring 412, and described neck ring is arranged on the proximal end 409a place of the hollow cylinder 410 of piston rod 409.The wall of neck ring 412 is not that interior diameter deflection and neck ring 412 does not allow to expand under stress.
The length of rigidity cable 421 is less than the distance that fixing point 420 and neck ring 412 are separated.
In the process of injection stage, allow projection 422 in the interior slip of hollow cylinder 410 of piston rod 409 until described projection contacts with neck ring 412 before injection just will finish.
When projection 422 contacts with described neck ring, do not allow it from described neck ring 412, to depart from, and the wall of described neck ring 412 is not deflection.Result is, described rigidity cable is fracture when injection finishes under the active force of helical spring 418 that makes piston rod 309 distal motion, thereby produces sound and inform that user injected.
Rigidity cable 421 can be made by any material that can rupture under stress.For example, rigidity cable 421 is made by the material of polypropylene or other easy fracture.
Device of the present invention allows user clearly to be informed and injected.This is particularly important in self-injection device, and in described self-injection device, injection for example, realizes by automaton (bias mechanism), and user is on its not impact.If user is generally the patient of uncomfortable use injection device, importantly user will be apprised of the time that injection finishes and product is fully discharged substantially, thereby user can be extracted safely from injection site injection device.
Claims (6)
1. one kind for injecting product (6) automatic injection in the device (1) of injection site (7), described product is entrained by container (2), described container has open proximal end (3) and carries distal end portion (4) and the piston (8) of closure substantially of pin (5), described pin provides outlet for the described product from described container, described piston is arranged in described container and can be with respect to described container distal motion, the motion distad of described piston makes described product discharge from described container by described pin, thereby realize the injection of described product, described device (1) comprising:
-piston rod (9; 109; 209; 309; 409), described piston rod is used for along distal direction, being attached to described piston (8) in injection process,
-bias mechanism (18; 118; 218; 418), described bias mechanism is for making described piston rod (9 at injection process; 109; 209; 309; 409) with respect to described container (2) distal motion,
-housing (14; 214), described housing design is for receiving at least in part described container (2), described piston rod (9; 109; 209; 309; 409) and described bias mechanism (18; 118; 218; 418),
-controlling organization (13,22; 110,121,117; 213,214a, 215; 309,321; 409,421), described controlling organization is designed for when produce sound indication near the described distal end portion (4) of described piston (8) at described container (2) and when described product (6) is substantially fully discharged from described container, thereby the indication that provides described product to inject for user
Described device (1) is characterised in that:
Described controlling organization comprises at least one first element (13; 121; 213; 321; 421) and at least one second element (22; 110,117; 214a, 215; 309; 409), described the first element is can be deflection or easy fracture and in injection process, be attached to directly or indirectly described housing (14; 214) or described piston rod (9; 109; 209; 309; 409), described the second element is attached to directly or indirectly described piston rod (9 in injection process; 109; 209; 309; 409) or described housing (14; 214),
Described the first element comprises easy fracture parts (321; 421), described easy fracture parts have the proximal end (321a that is attached to directly or indirectly described housing; 421a), and be directly or indirectly attached to described piston rod (309; 409) distal end portion (321b; 421b), described easy fracture parts are fracture when injection finishes under the effect of described bias mechanism, thereby produces described sound indication.
2. device as claimed in claim 1 (1), it is characterized in that, described easy fracture parts comprise the flexible wire rod (321) of have proximal end (321a) and distal end portion (321b), the proximal end (321a) of described flexible wire rod (321) is fixed to the fixing point (320) in the proximal region that is positioned at described housing, at fixing point described in injection process (320), with respect to described housing, fix, and the distal end portion (321b) of described flexible wire rod (321) is fixed to the proximal end (309a) of described piston rod (309), the length of described flexible wire rod (321) is less than when injection finishes the distance that the described proximal end (309a) of described piston rod (309) and described fixing point (320) are separated, described piston rod (309) motion distad under the effect of described bias mechanism makes described flexible wire rod (321) fracture when injection finishes.
3. device as claimed in claim 2 (1), is characterized in that, described wire rod (321) is made by nylon or polypropylene.
4. device as claimed in claim 1 (1), it is characterized in that, described piston rod (409) comprises hollow cylinder (410), described hollow cylinder is provided with neck ring (412) in the proximal end (409a) of this hollow cylinder, described easy fracture parts comprise the rigidity cable (421) of have proximal end (421a) and distal end portion (421b), the proximal end (421a) of described rigidity cable (421) is fixed to the fixing point (420) in the proximal region that is positioned at described housing, at fixing point described in injection process (420), with respect to described housing, fix, and the distal end portion (421b) of described rigidity cable (421) is received in described hollow cylinder (410) slidably, the described distal end portion (421b) of described rigidity cable (421) is provided with projection (422), described projection has the overall diameter that is greater than described neck ring (412) interior diameter, the length of described rigidity cable (421) is less than when injection finishes the distance that the described neck ring (412) of described piston rod (409) and described fixing point (420) are separated, described piston rod (409) motion distad under the effect of described bias mechanism makes described rigidity cable (421) fracture when injection finishes.
5. device as claimed in claim 4 (1), is characterized in that, described rigidity cable (421) is made by polypropylene.
6. the device (1) as described in any one in claim 1 to 4, is characterized in that, described the first element (13; 121; 213; 321; 421) with described bias mechanism (18; 118; 218; 418) difference.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201410161876.4A CN103920212B (en) | 2008-09-29 | 2008-09-29 | Automatic injecting device capable of giving sound indication when injection is completed |
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| Application Number | Priority Date | Filing Date | Title |
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| CN200880131863.5A CN102209563B (en) | 2008-09-29 | 2008-09-29 | Automatic injection device with audible indicator of completed injection |
| CN201410161876.4A CN103920212B (en) | 2008-09-29 | 2008-09-29 | Automatic injecting device capable of giving sound indication when injection is completed |
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| Application Number | Title | Priority Date | Filing Date |
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| CN200880131863.5A Division CN102209563B (en) | 2008-09-29 | 2008-09-29 | Automatic injection device with audible indicator of completed injection |
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| Publication Number | Publication Date |
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| CN103920212A true CN103920212A (en) | 2014-07-16 |
| CN103920212B CN103920212B (en) | 2017-04-12 |
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| CN201410161876.4A Active CN103920212B (en) | 2008-09-29 | 2008-09-29 | Automatic injecting device capable of giving sound indication when injection is completed |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109689130A (en) * | 2016-08-30 | 2019-04-26 | 赛诺菲-安万特德国有限公司 | Injection device |
| CN111282094A (en) * | 2020-03-05 | 2020-06-16 | 苏州恒瑞宏远医疗科技有限公司 | Automatic injection device and method of use |
| CN111463614A (en) * | 2020-03-05 | 2020-07-28 | 苏州恒瑞宏远医疗科技有限公司 | Mechanical transmission device |
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| WO2005070481A1 (en) * | 2004-01-23 | 2005-08-04 | The Medical House Plc | Injection device |
| DE102004052219A1 (en) * | 2004-10-27 | 2006-05-04 | Tecpharma Licensing Ag | Injection devices for delivering insulin with restrictor, comprises prestressed spring washer, bi/multi stable signal generating burst/place element and releasing element that emits signal with deformation |
| WO2007132353A2 (en) * | 2006-04-11 | 2007-11-22 | Becton Dickinson France S.A.S | Automatic injection device |
| DE102007013838A1 (en) * | 2007-03-22 | 2008-09-25 | Tecpharma Licensing Ag | Injection device with time-constant Ausschüttsignal |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2005070481A1 (en) * | 2004-01-23 | 2005-08-04 | The Medical House Plc | Injection device |
| DE102004052219A1 (en) * | 2004-10-27 | 2006-05-04 | Tecpharma Licensing Ag | Injection devices for delivering insulin with restrictor, comprises prestressed spring washer, bi/multi stable signal generating burst/place element and releasing element that emits signal with deformation |
| WO2007132353A2 (en) * | 2006-04-11 | 2007-11-22 | Becton Dickinson France S.A.S | Automatic injection device |
| DE102007013838A1 (en) * | 2007-03-22 | 2008-09-25 | Tecpharma Licensing Ag | Injection device with time-constant Ausschüttsignal |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109689130A (en) * | 2016-08-30 | 2019-04-26 | 赛诺菲-安万特德国有限公司 | Injection device |
| US11351304B2 (en) | 2016-08-30 | 2022-06-07 | Sanofi-Aventis Deutschland Gmbh | Injection device |
| CN111282094A (en) * | 2020-03-05 | 2020-06-16 | 苏州恒瑞宏远医疗科技有限公司 | Automatic injection device and method of use |
| CN111463614A (en) * | 2020-03-05 | 2020-07-28 | 苏州恒瑞宏远医疗科技有限公司 | Mechanical transmission device |
| CN111282094B (en) * | 2020-03-05 | 2020-11-10 | 苏州恒瑞宏远医疗科技有限公司 | Automatic injection device and method of use |
| CN111463614B (en) * | 2020-03-05 | 2021-05-18 | 苏州恒瑞宏远医疗科技有限公司 | Mechanical transmission device |
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|---|---|
| CN103920212B (en) | 2017-04-12 |
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