CN103920032A - Medicine for treating essential hypertension and preparation method thereof - Google Patents
Medicine for treating essential hypertension and preparation method thereof Download PDFInfo
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- CN103920032A CN103920032A CN201410141573.6A CN201410141573A CN103920032A CN 103920032 A CN103920032 A CN 103920032A CN 201410141573 A CN201410141573 A CN 201410141573A CN 103920032 A CN103920032 A CN 103920032A
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Abstract
The invention relates to a medicine for treating essential hypertension and a preparation method thereof. The medicine consists of the following raw materials by weight: 10-30g of salvia miltiorrhiza, 10-15g of Hangzhou white chrysanthemum, 10-15g of earthworm, 10-15g of fruits of Chinese magnoliavine, 10-15g of gardeniae, 10-15g of scutellaria baicalensis, 10-15g of medlar, 10-30g of corn stigmas, 5-10g of ginseng and 10-15g of hawthorn. The medicine disclosed by the invention, on the basis of knowledge of traditional Chinese medicine on hypertension, is prepared from pure natural Chinese herbal medicines, and has functions of removing liver heat and promoting diuresis, regulating blood fat, unblocking blood vessels, improving cardiovascular blood flow, inhibiting formation of atherosclerosis, improving serum cholesterol and enhancing an inhibiting effect; and the medicine is prepared into capsules convenient to be taken.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of medicine for the treatment of essential hypertension and preparation method thereof.
Background technology
Essential hypertension is a kind of commonly encountered diseases, frequently-occurring disease, is also the disease that a kind of mortality rate is higher.Epidemiological study prompting, below factor also may be relevant with hypertensive generation: obesity, smoking, excessive consumption of alcohol, low calcium, low magnesium and low potassium.As a rule, show as headache, dizzy, out of breath, tired, cardiopalmus, tinnitus, thereby cause the generation of vascular system disease.The hypertension initial stage just after psychentonia, anxious state of mind blood pressure temporarily raise, can recover subsequently normal, later hypertension is tending towards obviously and lasting gradually, but within one day daytime and night blood pressure still have obvious difference.Clinical manifestation Chang Yuxin, brain, renal insufficiency or the organ complication in hypertension later stage are relevant.The state of an illness has overall relevance and progressively expansionary, produces the physiological function pathological change of distinct program mainly with brain, maincenter, the heart, liver, kidney target organ and channels tissue, and its cause of disease is always had to multiple understanding.
Along with modernization medical science is to hypertensive understanding and improve, hypertension can be divided into constitutional and the large class of Secondary cases two.In most patients, hypertensive etiology unknown, is referred to as essential hypertension, accounts for the more than 95% of total hyperpietic; In less than 5% patient, hypertension is a kind of clinical manifestation of some disease, itself has clearly and the independently cause of disease, is called secondary hypertension.Essential hypertension, claim again hypertension, patient is except can causing the relevant symptom of hypertension itself, and long-term hypertension also can become the important risk factor of multiple cardiovascular and cerebrovascular disease, and affect important organ after one's own heart, the function of brain, kidney, finally can cause the nonfunction of these organs.
In view of above-mentioned defect, creator of the present invention has obtained this creation finally through long research and practice.
Summary of the invention
The object of the present invention is to provide a kind of medicine for the treatment of essential hypertension and preparation method thereof, in order to overcome above-mentioned technological deficiency.
For achieving the above object, the invention provides a kind of medicine for the treatment of essential hypertension, formed by the raw material of following weight fraction ratio:
Radix Salviae Miltiorrhizae 10～30g, Flos Chrysanthemi 10～15g, Pheretima 10～15g, Fructus Schisandrae Chinensis 10～15g, Fructus Gardeniae 10～15g, Radix Scutellariae 10～15g, Fructus Lycii 10～15g, Stigma Maydis 10～30g, Radix Ginseng 5～10g, Fructus Crataegi 10～15g.
Further, consisting of of above-mentioned each raw material:
Radix Salviae Miltiorrhizae 15～20g, Flos Chrysanthemi 10～13g, Pheretima 10～13g, Fructus Schisandrae Chinensis 10～13g, Fructus Gardeniae 10～13g, Radix Scutellariae 10～13g, Fructus Lycii 10～13g, Stigma Maydis 20～30g, Radix Ginseng 5～7g, Fructus Crataegi 10～13g.
Further, in the proportion of above-mentioned raw materials: Radix Salviae Miltiorrhizae 20g, Flos Chrysanthemi 10g, Pheretima 10g, Fructus Schisandrae Chinensis 10g, Fructus Gardeniae 10g, Radix Scutellariae 10g, Fructus Lycii 10g, Stigma Maydis 20g, Radix Ginseng 5g, Fructus Crataegi 10g.
Further, in above-mentioned manufacturing process, by the various powder that are crushed to, decocting boils 100 DEG C, decocts 30 minutes in boiled water, and decocting boils 3 times, adds water 3 liters, merging filtrate at every turn; Utilize crocus cloth coarse filtration, filter paper fine filtering; Utilize Rotary Evaporators, concentrated at 60 DEG C; Utilize thermostatic drying chamber, be dried 72 hours at 50 DEG C, obtain extractum; Extractum is pulverized, crossed 120 mesh sieves.
Further, described capsule is No. 0 capsule, and the capacity of No. 0 capsule is 0.68ml, 0.6g/ml powder charge powder 0.35 ± 3g.
The present invention also provides a kind of preparation method of medicine for the treatment of essential hypertension, comprises the steps:
Step a, the raw material of preparing following weight fraction ratio forms: Radix Salviae Miltiorrhizae 10～30g, Flos Chrysanthemi 10～15g, Pheretima 10～15g, Fructus Schisandrae Chinensis 10～15g, Fructus Gardeniae 10～15g, Radix Scutellariae 10～15g, Fructus Lycii 10～15g, Stigma Maydis 10～30g, Radix Ginseng 5～10g, Fructus Crataegi 10～15g.
Step b, pulverizes the raw material ingredients of above-mentioned preparation, and decocting boils, and filters, and concentrated medicament is dry, extract powder is broken to 120 orders and loads capsule.
Beneficial effect of the present invention is compared with prior art: of the present invention based on Chinese medicine to hypertensive understanding, selecting pure natural Chinese herbal medicine is raw material, liver heat removing diuretic, adjusting blood fat, unobstructed blood vessels, improve cardiovascular blood flow, stop atherogenesis, improve serum cholesterol and increase inhibitory action, be prepared into the capsule of conveniently taking.
Detailed description of the invention
Below, the present invention above-mentioned technical characterictic and advantage with other are described in more detail.
The present invention treats the medicine of essential hypertension, and treatment essential hypertension, is made up of the raw material of following weight fraction ratio:
Radix Salviae Miltiorrhizae 10～30g, Flos Chrysanthemi 10～15g, Pheretima 10～15g, Fructus Schisandrae Chinensis 10～15g, Fructus Gardeniae 10～15g, Radix Scutellariae 10～15g, Fructus Lycii 10～15g, Stigma Maydis 10～30g, Radix Ginseng 5～10g, Fructus Crataegi 10～15g.
Better when the raw material of above-mentioned weight fraction ratio consists of following value: Radix Salviae Miltiorrhizae 15～20g, Flos Chrysanthemi 10～13g, Pheretima 10～13g, Fructus Schisandrae Chinensis 10～13g, Fructus Gardeniae 10～13g, Radix Scutellariae 10～13g, Fructus Lycii 10～13g, Stigma Maydis 20～30g, Radix Ginseng 5～7g, Fructus Crataegi 10～13g.
Wherein, in the proportion of above-mentioned raw materials: Radix Salviae Miltiorrhizae 20g, Flos Chrysanthemi 10g, Pheretima 10g, Fructus Schisandrae Chinensis 10g, Fructus Gardeniae 10g, Radix Scutellariae 10g, Fructus Lycii 10g, Stigma Maydis 20g, Radix Ginseng 5g, Fructus Crataegi 10g.Best results under this ratio condition.
The preparation method that the present invention treats essential hypertension medicine comprises the steps:
Step a, the raw material of preparing following weight fraction ratio forms: Radix Salviae Miltiorrhizae 10～30g, Flos Chrysanthemi 10～15g, Pheretima 10～15g, Fructus Schisandrae Chinensis 10～15g, Fructus Gardeniae 10～15g, Radix Scutellariae 10～15g, Fructus Lycii 10～15g, Stigma Maydis 10～30g, Radix Ginseng 5～10g, Fructus Crataegi 10～15g.
Step b, pulverizes the raw material ingredients of above-mentioned preparation, and decocting boils, and filters, and concentrated medicament is dry, extract powder is broken to 120 orders and loads capsule.
In above-mentioned manufacturing process, by the various powder that are crushed to, decocting boils 100 DEG C, decocts 30 minutes in boiled water, and decocting boils 3 times, adds water 3 liters, merging filtrate at every turn; Utilize crocus cloth coarse filtration, filter paper fine filtering; Utilize Rotary Evaporators, concentrated at 60 DEG C; Utilize thermostatic drying chamber, be dried 72 hours at 50 DEG C, obtain extractum; Extractum is pulverized, crossed 120 mesh sieves.
Described capsule is No. 0 capsule, and the capacity of No. 0 capsule is 0.68ml, 0.6g/ml powder charge powder 0.35 ± 3g.
The container that capsule is housed should be placed in shady and cool ventilation place, avoids sun exposure and close thermal source.
Radix Salviae Miltiorrhizae, Pheretima, activating blood circulation to dissipate blood stasis, Fructus Schisandrae Chinensis, Fructus Gardeniae, Radix Scutellariae, Fructus Crataegi removing heat from the liver to lower the high blood pressure, relieving restlessness is calmed the nerves, logical blood circulation regulating, blood vessel dilating, alleviating vascular spasm, improve blood vessel Intradermal cellulose content, reduce the viscosity of blood fat and blood, can make blood-retention or long-pending silt dissipate and gush and separate in absorbed into serum circulation or from stool.
The foregoing is only preferred embodiment of the present invention, is only illustrative for invention, and nonrestrictive.Those skilled in the art is understood, and in the spirit and scope that limit, can carry out many changes to it in invention claim, amendment, and even equivalence, but all will fall within the scope of protection of the present invention.
Claims (6)
1. a medicine for the treatment of essential hypertension, is characterized in that, is made up of the raw material of following weight fraction ratio:
Radix Salviae Miltiorrhizae 10～30g, Flos Chrysanthemi 10～15g, Pheretima 10～15g, Fructus Schisandrae Chinensis 10～15g, Fructus Gardeniae 10～15g, Radix Scutellariae 10～15g, Fructus Lycii 10～15g, Stigma Maydis 10～30g, Radix Ginseng 5～10g, Fructus Crataegi 10～15g.
2. the medicine for the treatment of essential hypertension according to claim 1, is characterized in that, the consisting of of above-mentioned each raw material:
Radix Salviae Miltiorrhizae 15～20g, Flos Chrysanthemi 10～13g, Pheretima 10～13g, Fructus Schisandrae Chinensis 10～13g, Fructus Gardeniae 10～13g, Radix Scutellariae 10～13g, Fructus Lycii 10～13g, Stigma Maydis 20～30g, Radix Ginseng 5～7g, Fructus Crataegi 10～13g.
3. the medicine for the treatment of essential hypertension according to claim 1 and 2, it is characterized in that, in the proportion of above-mentioned raw materials: Radix Salviae Miltiorrhizae 20g, Flos Chrysanthemi 10g, Pheretima 10g, Fructus Schisandrae Chinensis 10g, Fructus Gardeniae 10g, Radix Scutellariae 10g, Fructus Lycii 10g, Stigma Maydis 20g, Radix Ginseng 5g, Fructus Crataegi 10g.
4. the medicine for the treatment of essential hypertension according to claim 1 and 2, is characterized in that, in above-mentioned manufacturing process, by the various powder that are crushed to, decocting boils 100 DEG C, decocts 30 minutes in boiled water, and decocting boils 3 times, adds water 3 liters, merging filtrate at every turn; Utilize crocus cloth coarse filtration, filter paper fine filtering; Utilize Rotary Evaporators, concentrated at 60 DEG C; Utilize thermostatic drying chamber, be dried 72 hours at 50 DEG C, obtain extractum; Extractum is pulverized, crossed 120 mesh sieves.
5. the medicine for the treatment of essential hypertension according to claim 4, is characterized in that, described capsule is No. 0 capsule, and the capacity of No. 0 capsule is 0.68ml, 0.6g/ml powder charge powder 0.35 ± 3g.
6. a preparation method for the treatment of the medicine of essential hypertension, is characterized in that, comprises the steps:
Step a, the raw material of preparing following weight fraction ratio forms: Radix Salviae Miltiorrhizae 10～30g, Flos Chrysanthemi 10～15g, Pheretima 10～15g, Fructus Schisandrae Chinensis 10～15g, Fructus Gardeniae 10～15g, Radix Scutellariae 10～15g, Fructus Lycii 10～15g, Stigma Maydis 10～30g, Radix Ginseng 5～10g, Fructus Crataegi 10～15g.
Step b, pulverizes the raw material ingredients of above-mentioned preparation, and decocting boils, and filters, and concentrated medicament is dry, extract powder is broken to 120 orders and loads capsule.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410141573.6A CN103920032A (en) | 2014-04-04 | 2014-04-04 | Medicine for treating essential hypertension and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410141573.6A CN103920032A (en) | 2014-04-04 | 2014-04-04 | Medicine for treating essential hypertension and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105902762A (en) * | 2016-06-18 | 2016-08-31 | 衣振兴 | Pharmaceutical composition for treating primary hypertension and preparation method and application thereof |
| CN106038925A (en) * | 2016-08-10 | 2016-10-26 | 衣明春 | Medicinal composition for treating primary hypertension, and preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102319368A (en) * | 2011-09-20 | 2012-01-18 | 叶立新 | Chinese medicinal composition for treating hypertension and preparation method thereof |
| CN103182008A (en) * | 2011-12-29 | 2013-07-03 | 晓健科技（大连）有限公司 | Preparation method for traditional Chinese medicine used for stabilizing and reducing blood pressure |
-
2014
- 2014-04-04 CN CN201410141573.6A patent/CN103920032A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102319368A (en) * | 2011-09-20 | 2012-01-18 | 叶立新 | Chinese medicinal composition for treating hypertension and preparation method thereof |
| CN103182008A (en) * | 2011-12-29 | 2013-07-03 | 晓健科技（大连）有限公司 | Preparation method for traditional Chinese medicine used for stabilizing and reducing blood pressure |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105902762A (en) * | 2016-06-18 | 2016-08-31 | 衣振兴 | Pharmaceutical composition for treating primary hypertension and preparation method and application thereof |
| CN106038925A (en) * | 2016-08-10 | 2016-10-26 | 衣明春 | Medicinal composition for treating primary hypertension, and preparation method and application thereof |
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Application publication date: 20140716 |
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