CN103893314B

CN103893314B - A kind of Chinese medicine preparation for the treatment of expectorant blood stasis type cyclomastopathy

Info

Publication number: CN103893314B
Application number: CN201410138607.6A
Authority: CN
Inventors: 马丽红
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-03-30
Filing date: 2014-03-30
Publication date: 2015-09-02
Anticipated expiration: 2034-03-30
Also published as: CN103893314A

Abstract

The invention discloses a kind of Chinese medicine preparation for the treatment of expectorant blood stasis type cyclomastopathy.Patient's emptiness of spleen and stomach, or eating and drinking without temperance, or melancholy impairing the spleen, or angry impairing the liver, edema with the liver involved gram spleen soil causes dysfunction of the spleen in transportation, water-damp not being transformed, gathers and is expectorant; Qi being the governor of blood, blood being the material foundation of QI, the capable then blood of gas, the stagnation of QI is blood addiction then, and accumulation of phlegm in the hypochondrium is tied mutually in newborn network and produces nodules of the breast.Dialectical treatment expectorant blood stasis type cyclomastopathy should with blood circulation promoting and blood stasis dispelling, dissipating phlegm and resolving masses for principle.For this reason, the present invention selects to have Selenitum, Semen Melo, Ma Jiaoer, Ramulus et Folium Dichroae febrifugae, Radix Anemones Tomentosae, Herba Senecionis nudicaulis, Radix Buddlejae Butterflybush, Coniogramme japonica (Thunb.) Diels, Herba Nanocnides pilosae, Flos Pruni mume make Chinese medicine preparation.By the court through clinical trial, evident in efficacy, total effective rate 97.5%; And treatment cost is low, method is easy.

Description

A kind of Chinese medicine preparation for the treatment of expectorant blood stasis type cyclomastopathy

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine preparation for the treatment of expectorant blood stasis type cyclomastopathy.

Background technology

Cyclomastopathy is the benign proliferative lesion of female normal mammary gland tissue, the non-tumor of non-inflammation, is also the modal mastopathy of modern female.The medicine that doctor trained in Western medicine treats cyclomastopathy at present has: (1) antiestrogen: as tamoxifen, it can obviously alleviate mastalgia symptom, make lump deliquescing or reduce, but life-time service can cause menoxenia, amenorrhea, affect ovarian function, or increase the danger that carcinoma of endometrium occurs.(2) androgens medicine: androgens medicine has the effect removing mastalgia, dissipation lump, and side effect is larger.(3) lisuride class medicine: the conventional hidden booth of sea, is suitable for the patient that prolactin level is higher, can alleviates clinical symptoms in various degree.Side effect has Nausea and vomiting, dizzy, orthostatic hypotension etc.Thyroxine by suppressing the reaction that stimulates thyrotrophin-releasing hormone of hypophysis, and reaches the effect reducing prolactin antagonist release and secrete, its side effect had palpitation, tremble, hyperhidrosis, excitement, insomnia etc.(4) other: as 5% potassium iodide can produce lutropin by Stimulation of Pituitary Gland, make follicular cyst of ovary luteinization, estrogen reduces, and has hard masses softening and resolving, lenitive effect, but easily recurs after drug withdrawal.Traditional Chinese medical herbal treatment cyclomastopathy, from entirety, dialectically to combine with differential diagnosis of diseases, can from many aspects, multiple angle adjustment endocrine, enhancing human body immunity power.Relative to western medicine and medical practitioners treatment, Chinese medicine is effective in cure good, the features such as side effect is little, stable curative effect, effectively can improve the quality of life of patient.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of expectorant blood stasis type cyclomastopathy.Patient's emptiness of spleen and stomach, or eating and drinking without temperance, or melancholy impairing the spleen, or angry impairing the liver, edema with the liver involved gram spleen soil causes dysfunction of the spleen in transportation, water-damp not being transformed, gathers and is expectorant; Qi being the governor of blood, blood being the material foundation of QI, the capable then blood of gas, the stagnation of QI is blood addiction then.Accumulation of phlegm in the hypochondrium is tied mutually in newborn network and produces nodules of the breast.Dialectical treatment expectorant blood stasis type cyclomastopathy should with blood circulation promoting and blood stasis dispelling, dissipating phlegm and resolving masses for principle.

Treat a Chinese medicine preparation for expectorant blood stasis type cyclomastopathy, the Chinese medicine preparation of this treatment expectorant blood stasis type cyclomastopathy is made up of the Chinese medicine of following weight portion: Selenitum 9-15 part, Semen Melo 9-15 part, horse hand over youngster 15-25 part, Ramulus et Folium Dichroae febrifugae 3-6 part, Radix Anemones Tomentosae 3-9 part, Herba Senecionis nudicaulis 9-15 part, Radix Buddlejae Butterflybush 9-15 part, Coniogramme japonica (Thunb.) Diels 9-15 part, Herba Nanocnides pilosae 15-25 part, Flos Pruni mume 2-4 part.

Preferably, Selenitum 12 parts, Semen Melo 12 parts, horse hand over youngster 20 parts, Ramulus et Folium Dichroae febrifugae 4 parts, Radix Anemones Tomentosae 6 parts, Herba Senecionis nudicaulis 12 parts, Radix Buddlejae Butterflybush 12 parts, Coniogramme japonica (Thunb.) Diels 12 parts, Herba Nanocnides pilosae 20 parts, Flos Pruni mume 3 parts.

Above-mentioned Chinese medicine decocting is made decoction by preparation method.

Fang Zhong: Selenitum nourishing YIN to lower pathogenic fire, softening the hard mass expectorant; Semen Melo lung heat clearing intestine moistening and in quench the thirst, repercussive eliminating stagnation; Horse hands over youngster's detumescence and drawing out poison, phlegm resolving powder knot, removing food stagnancy; Ramulus et Folium Dichroae febrifugae eliminating phlegm dissipating bond; Radix Anemones Tomentosae resolving phlegm and dissipating blood stasis; Herba Senecionis nudicaulis, Radix Buddlejae Butterflybush region are invigorated blood circulation, regulating menstruation; The pain relieving of Coniogramme japonica (Thunb.) Diels promoting blood flow to regulate menstruation, expelling phlegm for arresting cough; Herba Nanocnides pilosae promoting blood circulation to restore menstrual flow; Flos Pruni mume is soothing the liver to reduce phlegm.

Clinical data

1,40 routine cases selected by physical data are in January, 2010 ~ 2011 year January patient to our hospital, are expectorant blood stasis type cyclomastopathy through clinical definite, 23 ~ 41 years old age, 30.01 years old mean age.The course of disease 1 week ~ 12 months 21 examples; 1 ~ 3 year person 10 example, more than 3 years person 9 examples.One-sided patient 31 example, bilateral patient 9 example.

2, diagnostic criteria is formulated with reference to the diagnostic criteria of breast disease Professional Committee of Society of Surgery of China Association of Traditional Chinese Medicine in 2002.Standard is as follows: 1. symptom and sign: breast has distending pain in various degree, twinges and dull pain, can have dependency with menstruation, emotion changes, continuous 3 months or be interrupted pain within 3 ~ 6 months, do not alleviate; There is single or multiple lump in breast, lump dispersibles in whole breast, unclear with surrounding tissue boundary, pushes away movable, may touch a tender spot, can the growth and decline with the change of emotion and menstrual cycle, and some patients can have nipple discharge or rash to itch.2. auxiliary examination: all cases all take the photograph sheet, the inspection of breast high-frequency color doppler ultrasound through mammary gland platinum target, are diagnosed as cyclomastopathy.

Dialectical disease: primary symptom: 1. breast twinge; 2. lump is multiformity, obscure boundary, and matter is tough; 3. dark red or the livid purple or tongue limit point of tongue has addiction speckle, or Sublingual venation is slightly swollen, livid purple.Secondary disease: 1. distending pain of the breast and (or) lump not quite relevant to menstruation, emotion; 2. delayed period, passes through smooth or with clot; 3. greasy fur on tongue, hesitant pulse, string or cunning.

Standard: tool 3 primary symptoms or 2 primary symptoms+2 diseases.

3, Therapeutic Method patient takes Chinese medicine preparation of the present invention, takes Selenitum 12g, Semen Melo 12g, horse hands over youngster 20g, Ramulus et Folium Dichroae febrifugae 4g, Radix Anemones Tomentosae 6g, Herba Senecionis nudicaulis 12g, Radix Buddlejae Butterflybush 12g, Coniogramme japonica (Thunb.) Diels 12g, Herba Nanocnides pilosae 20g, Flos Pruni mume 3g.Decocting extracting juice.Every day 2 times, in 30 minutes after meal decoction being taken warmly, after clean period, first day started medication, until next menstrual onset is discontinued medication, a menstrual cycle is a course for the treatment of, continuously treatment 2 menstrual cycle.

4, criterion of therapeutical effect recovery from illness: mastalgia and lump disappear completely.Effective: after premenstrual, angry and fatigue, the degree of mastalgia obviously alleviates before comparatively treating, and lump volume-diminished is over half, has slight tenderness.Effective: after premenstrual, angry and fatigue, mastalgia alleviates, the deliquescing of lump quality, half that volume-diminished is not enough.Invalid: after treatment, symptom and sign fail to improve, even increase the weight of.

5, the routine patient of therapeutic outcome 40 wherein fully recovers 14 examples (35%), effective 15 examples (37.5%), effective 10 examples (25%), invalid 1 example (2.5%), and total effective rate 97.5% is evident in efficacy.Period in a medicine, patient does not have obvious untoward reaction to occur.

Detailed description of the invention

Embodiment one: take Selenitum 12g, Semen Melo 12g, horse hands over youngster 20g, Ramulus et Folium Dichroae febrifugae 4g, Radix Anemones Tomentosae 6g, Herba Senecionis nudicaulis 12g, Radix Buddlejae Butterflybush 12g, Coniogramme japonica (Thunb.) Diels 12g, Herba Nanocnides pilosae 20g, Flos Pruni mume 3g, traditionally decocting makes decoction.

Embodiment two: take Selenitum 15g, Semen Melo 9g, horse hands over youngster 25g, Ramulus et Folium Dichroae febrifugae 3g, Radix Anemones Tomentosae 9g, Herba Senecionis nudicaulis 9g, Radix Buddlejae Butterflybush 15g, Coniogramme japonica (Thunb.) Diels 9g, Herba Nanocnides pilosae 25g, Flos Pruni mume 2g, traditionally decocting makes decoction.

Embodiment three: take Selenitum 9g, Semen Melo 15g, horse hands over youngster 15g, Ramulus et Folium Dichroae febrifugae 6g, Radix Anemones Tomentosae 3g, Herba Senecionis nudicaulis 15g, Radix Buddlejae Butterflybush 9g, Coniogramme japonica (Thunb.) Diels 15g, Herba Nanocnides pilosae 15g, Flos Pruni mume 4g, traditionally decocting makes decoction.

Claims

1. treat the Chinese medicine preparation of expectorant blood stasis type cyclomastopathy for one kind, it is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight: Selenitum 12g, Semen Melo 12g, horse hand over youngster 20g, Ramulus et Folium Dichroae febrifugae 4g, Radix Anemones Tomentosae 6g, Herba Senecionis nudicaulis 12g, Radix Buddlejae Butterflybush 12g, Coniogramme japonica (Thunb.) Diels 12g, Herba Nanocnides pilosae 20g, Flos Pruni mume 3g, and traditionally decocting makes decoction.