CN103886801A - Experiment device for measuring toe tumefaction of mice - Google Patents
Experiment device for measuring toe tumefaction of mice Download PDFInfo
- Publication number
- CN103886801A CN103886801A CN201210561733.3A CN201210561733A CN103886801A CN 103886801 A CN103886801 A CN 103886801A CN 201210561733 A CN201210561733 A CN 201210561733A CN 103886801 A CN103886801 A CN 103886801A
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- China
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- test tube
- experiment device
- electronic balance
- tumefaction
- mice
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention belongs to the technical field of veterinary drugs and discloses an experiment device for measuring toe tumefaction of mice. The experiment device includes a test tube (1) and an electronic balance (2). The experiment device is characterized in that the top end of the test tube (1) is provided with an opening; and a horizontally downward conduit is connected to the opening so that during measurement, overflowed liquid is guided to the electronic balance.
Description
Technical field
The invention belongs to medical research field, relate to a kind of experiment of measuring the swelling of rat toes and put.
Technical background
Rat toes inflammation swelling method is the most frequently used acute nonspecific inflammation test model in research anti-inflammatory drug test, the test method of measuring swelling comprises Zhou Changfa, Thickness Method, volumetric method or glass volumetric method, wherein affected by subjective factor larger for Zhou Changfa and Thickness Method, and accuracy and repeatability are poor.Volumetric method is comparatively conventional, also more accurate, but equipment therefor and all comparatively complicated with method is not easy to a large amount of zooperies.Read glass scale and also have larger personal error, and the selected container operation of glass volumetric method is also easy not, the inconvenience that above-mentioned test method all exists sobering animal to bring because arresting difficulty in the time carrying out simultaneously.
summary of the invention
The object of patent of the present invention is to provide the experimental provision of toes swelling under a kind of simple, rapid, accurate, safe mensuration rat waking state.
Patent of the present invention is achieved in that experimental provision disclosed by the invention, formed by test tube (1) and electronic balance (2), it is characterized in that there is an opening on test tube (1) top, opening part connects the downward conduit of a level, when measurement, the liquid of overflow is imported in electronic balance.Filled with fluid in conduit when measurement, the liquid filling is ultrapure water.The preferred technical scheme of patent of the present invention is by diameter 4cm, and the glass test tube of high 10 ~ 15cm is fixed on iron stand, and under test tube, placing is electronic balance with numeral, and its sensitivity is 0.1mg, one bottle of ultrapure water, one, taper Conscious Rat test cover.
When measurement, catch rat tail on the other hand, another hand is caught the closing in rope of mouse cover, allows rat naturally creep into mouse cover, tightens up rope, fastens.A little ultrapure water is overflowed from test tube ultrapure water injecting tube and fall into balance on goods and services, the weight of the ultrapure water that recording balance shows is as basis weight.In mouse cover, draw out hind leg to be measured, stretched fixing, immerse in the ultrapure water in test tube, that ultrapure water liquid level is equal with foot pad upper limb, the actual weight of the ultrapure water that recorded electronic balance shows, the actual weight that is ultrapure water deducts the weight that basis weight is exactly this toes discharge ultrapure water, is converted into as required volume.
Measure with this device that the toes swelling coefficient of variation of Conscious Rat is little, reproducible, error is little, accuracy is high, warranty test rat still can carry out this test under waking state.
Claims (4)
1. the invention discloses a kind of experimental provision of measuring the swelling of rat toes, formed by test tube (1) and electronic balance (2), it is characterized in that there is an opening on test tube (1) top, opening part connects the downward conduit of a level, when measurement, the liquid of overflow is imported in electronic balance.
2. device according to claim 1, filled with fluid in conduit while it is characterized in that measuring.
3. device according to claim 1, is characterized in that filled liquid is ultrapure water.
4. device according to claim 1, is characterized in that, by diameter 4cm, the glass test tube of high 10 ~ 15cm is fixed on iron stand, and under test tube, placing is electronic balance with numeral, and its sensitivity is 0.1mg.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210561733.3A CN103886801A (en) | 2012-12-22 | 2012-12-22 | Experiment device for measuring toe tumefaction of mice |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210561733.3A CN103886801A (en) | 2012-12-22 | 2012-12-22 | Experiment device for measuring toe tumefaction of mice |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103886801A true CN103886801A (en) | 2014-06-25 |
Family
ID=50955668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210561733.3A Pending CN103886801A (en) | 2012-12-22 | 2012-12-22 | Experiment device for measuring toe tumefaction of mice |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103886801A (en) |
-
2012
- 2012-12-22 CN CN201210561733.3A patent/CN103886801A/en active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140625 |