CN103877542B - One is fallen dozen temperature and is pasted and its preparation method - Google Patents
One is fallen dozen temperature and is pasted and its preparation method Download PDFInfo
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- CN103877542B CN103877542B CN201410093672.1A CN201410093672A CN103877542B CN 103877542 B CN103877542 B CN 103877542B CN 201410093672 A CN201410093672 A CN 201410093672A CN 103877542 B CN103877542 B CN 103877542B
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- 239000000843 powder Substances 0.000 claims abstract description 20
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- 239000002674 ointment Substances 0.000 claims description 23
- 239000000463 material Substances 0.000 claims description 18
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 16
- 108010010803 Gelatin Proteins 0.000 claims description 12
- 229920000159 gelatin Polymers 0.000 claims description 12
- 239000008273 gelatin Substances 0.000 claims description 12
- 235000019322 gelatine Nutrition 0.000 claims description 12
- 235000011852 gelatine desserts Nutrition 0.000 claims description 12
- 238000003756 stirring Methods 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 8
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- 238000010438 heat treatment Methods 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 238000007789 sealing Methods 0.000 claims description 6
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 4
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims description 4
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 4
- 241000723346 Cinnamomum camphora Species 0.000 claims description 4
- 229920002125 Sokalan® Polymers 0.000 claims description 4
- 241000234314 Zingiber Species 0.000 claims description 4
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- 238000009835 boiling Methods 0.000 claims description 4
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims description 4
- 229940116229 borneol Drugs 0.000 claims description 4
- 229930008380 camphor Natural products 0.000 claims description 4
- 229960000846 camphor Drugs 0.000 claims description 4
- 239000001325 capsicum annuum l. var. longum oleoresin Substances 0.000 claims description 4
- 229960001631 carbomer Drugs 0.000 claims description 4
- 239000006185 dispersion Substances 0.000 claims description 4
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims description 4
- 235000010228 ethyl p-hydroxybenzoate Nutrition 0.000 claims description 4
- 239000004403 ethyl p-hydroxybenzoate Substances 0.000 claims description 4
- 229940043351 ethyl-p-hydroxybenzoate Drugs 0.000 claims description 4
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 claims description 4
- 235000008397 ginger Nutrition 0.000 claims description 4
- 239000010649 ginger oil Substances 0.000 claims description 4
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 4
- 235000012658 paprika extract Nutrition 0.000 claims description 4
- DYUUPIKEWLHQGQ-SDXBLLFJSA-N paprika oleoresin Chemical compound C(\[C@]12[C@@](O1)(C)C[C@@H](O)CC2(C)C)=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=C[C@H]1C(C)=C[C@H](O)CC1(C)C DYUUPIKEWLHQGQ-SDXBLLFJSA-N 0.000 claims description 4
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 4
- 238000010298 pulverizing process Methods 0.000 claims description 4
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 4
- 239000010409 thin film Substances 0.000 claims description 4
- 229940099259 vaseline Drugs 0.000 claims description 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 3
- -1 polyoxyethylene Polymers 0.000 claims description 2
- 208000006820 Arthralgia Diseases 0.000 abstract description 7
- 208000025747 Rheumatic disease Diseases 0.000 abstract description 7
- 230000000552 rheumatic effect Effects 0.000 abstract description 7
- 208000026137 Soft tissue injury Diseases 0.000 abstract description 6
- 208000002193 Pain Diseases 0.000 abstract description 3
- 239000008280 blood Substances 0.000 abstract description 2
- 210000004369 blood Anatomy 0.000 abstract description 2
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- 238000010792 warming Methods 0.000 abstract description 2
- 244000144730 Amygdalus persica Species 0.000 abstract 1
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- 235000003717 Boswellia sacra Nutrition 0.000 abstract 1
- 240000007551 Boswellia serrata Species 0.000 abstract 1
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- 235000008671 Calycanthus floridus Nutrition 0.000 abstract 1
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- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 241000218158 Clematis Species 0.000 abstract 1
- 240000007311 Commiphora myrrha Species 0.000 abstract 1
- 235000006965 Commiphora myrrha Nutrition 0.000 abstract 1
- 244000163122 Curcuma domestica Species 0.000 abstract 1
- 235000003392 Curcuma domestica Nutrition 0.000 abstract 1
- 239000004863 Frankincense Substances 0.000 abstract 1
- 241001506304 Kadsura japonica Species 0.000 abstract 1
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- 244000148992 Lindera benzoin Species 0.000 abstract 1
- 235000004520 Lindera benzoin Nutrition 0.000 abstract 1
- 235000008262 Lindera benzoin var. benzoin Nutrition 0.000 abstract 1
- 241000218378 Magnolia Species 0.000 abstract 1
- 235000007265 Myrrhis odorata Nutrition 0.000 abstract 1
- 240000005001 Paeonia suffruticosa Species 0.000 abstract 1
- 235000003889 Paeonia suffruticosa Nutrition 0.000 abstract 1
- 239000006002 Pepper Substances 0.000 abstract 1
- 235000016761 Piper aduncum Nutrition 0.000 abstract 1
- 235000017804 Piper guineense Nutrition 0.000 abstract 1
- 244000203593 Piper nigrum Species 0.000 abstract 1
- 235000008184 Piper nigrum Nutrition 0.000 abstract 1
- 235000006040 Prunus persica var persica Nutrition 0.000 abstract 1
- 240000004980 Rheum officinale Species 0.000 abstract 1
- 235000008081 Rheum officinale Nutrition 0.000 abstract 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 abstract 1
- 240000003248 Zanthoxylum nitidum Species 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 235000003373 curcuma longa Nutrition 0.000 abstract 1
- 239000010446 mirabilite Substances 0.000 abstract 1
- 235000013976 turmeric Nutrition 0.000 abstract 1
- 208000034656 Contusions Diseases 0.000 description 9
- 206010024453 Ligament sprain Diseases 0.000 description 9
- 230000001684 chronic effect Effects 0.000 description 9
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- 208000010040 Sprains and Strains Diseases 0.000 description 6
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- 210000000544 articulatio talocruralis Anatomy 0.000 description 2
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- 210000000323 shoulder joint Anatomy 0.000 description 2
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- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to one and fall dozen temperature subsides and its preparation method, this falls dozen temperature subsides and comprises medicinal powder, this medicinal powder comprises the composition of following weight part: Herba Lycopodii 400, Herba Lycopodii 200, myrrh 128, Shinyleaf Pricklyash Root 100, Radix Angelicae Sinensis 350, the radix paeoniae rubrathe 190, Fructus Aurantii 125, Radix Glycyrrhizae 100, rhizome of chuanxiong 350, Tree Peony Bark 190, Root of Sixpetal Clematis 125, levisticum 100, rheum officinale 320, the root of three-nerved spicebush 190, Kadsura Pepper Stem 125, notopterygium root 100, Herba Lycopi 320, rhizoma cyperi 190, bush 125, safflower 320, Folium Hibisci Mutabilis 150, dried orange peel 125, ramulus mori 270, Yanhusuo 150, cassia twig 125, radix bupleuri 270, mirabilite 125, root tuber of aromatic turmeric 125, tarragon 200, frankincense 128, the bark of official magnolia 125, peach kernel 200. dozen temperature subsides of falling of the present invention are mainly used in warming channel to dredge meridian, promoting circulation of blood pain relieving, for rheumatic arthralgia, and the treatment of soft tissue injury.
Description
Technical field
The present invention relates to one and fall dozen temperature subsides and its preparation method, particularly relate to one and be used for the treatment of rheumatic arthralgia, temperature subsides and its preparation method are beaten in falling of soft tissue injury.
Background technology
Along with the development of society, the work of people becomes day by day busy. Simultaneously, also bringing the healthy hidden danger that some can not be ignored, wherein rheumatic arthralgia and soft tissue injury are comparatively common.
Rheumatic arthralgia refers to the illness causing podomere pain, numbness, significant deformation, joint stuffiness because of outer heresy invasion and attack limbs passages through which vital energy circulates. Common are rheumatism, rheumatoid arthritis, ankylosing spondylitis, traumatic arthritis, chronic scapulohumeral periarthritis, sciatica, chronic lumbar internal lesion caused by overexertion, neck, lumbar hyperosteogency, prolapse of lumbar intervertebral disc, intervertebral foramina stenosis disease, women's apoplexy in postpartum etc. Have on clinical difficulty gradual, touching more, the feature of recurrent exerbation, be a kind of treat rather thorny common disease and frequently-occurring disease, be the chronic disease of a kind of great harm working people's physical and mental health.
The existing treatment rheumatic arthralgia of existing market, or be use hormones and biotechnological formulation, its treatment cost height, medicine toxic side effect is many, is unfavorable for HUMAN HEALTH; It is difficult to absorb, and drug effect is low.
Summary of the invention
For solving the problems of the technologies described above, the present invention provides one to be used for the treatment of rheumatic arthralgia, and temperature subsides and its preparation method are beaten in falling of soft tissue injury.
The present invention is the technical scheme that technical solution problem adopts:
One is fallen dozen temperature and is pasted, and by weight, comprising:
Wherein, described medicinal powder comprises by weight:
Prepare above-mentioned falling and beat the warm method pasted, comprise the following steps:
1) medicinal material is pulverized respectively, it is mixed and made into medicinal powder by above-mentioned weight ratio;
2) prepare gelatin solution: in 10kg water, add 2kg glycerine, stop heating after boiling, add 3kg gelatin and be stirred to and dissolve completely, for subsequent use;
3) medicinal powder 20kg, ginger powder 4kg, PEO3kg and carbomer 1kg are mixed;
4) after glycerine 10kg and sodium polyacrylate 1kg being stirred to dispersion, add 8kg water, pour in step 3) gained mixture, stir evenly;
5) step 2 is then added) the middle gelatin solution prepared, stir into plasticity-material;
6) sanitas is added: with 0.4kg dissolve with ethanol borneol 0.33kg, camphor 0.17kg, Tegosept M 0.08kg and ethyl p-hydroxybenzoate 0.08kg, add gained material in step 5);
7) heating solution is added: take ginger oil essence 0.17kg, paprika oleoresin 1.2kg, add gained material in step 6);
8) finally add Vaseline 5kg, it is stirred to flexible paste.
Preferably, in above-mentioned preparation method, 100 order sieves will be crossed after described pulverizing medicinal materials in step 1).
Preferably, the method beaten temperature and paste is fallen in above-mentioned preparation, further comprising the steps:
1), described flexible ointment it is twisted into cylinder shape, utilizes tabletting machine to pull film that ointment is pressed into sheet;
2), sheet ointment by punch die machine, every sheet ointment is made to be complete rectangle;
3), tablet tear thin film, the glue face not having film one side to be pasted onto back of the body glue, cover the back of the body and paste;
4) tablet, good for the dress back of the body pasted loads aluminizes in interior bag, sealing.
Fall, for the preparation of above-mentioned, the medicinal powder beaten temperature and paste, by weight, comprising:
The useful effect of the present invention is: dozen temperature subsides of falling of the present invention are mainly used in warming channel to dredge meridian, promoting circulation of blood pain relieving, for rheumatic arthralgia, and the treatment of soft tissue injury.
The present invention fall beat temperature paste using method be external application, be affixed on affected part. Every day pastes once, each 4-6 hour.
Embodiment
Embodiment 1
One is fallen dozen temperature and is pasted, and by weight, comprising:
Wherein, described medicinal powder comprises by weight:
Prepare above-mentioned falling and beat the warm method pasted, comprise the following steps:
1) by pulverizing medicinal materials, it is mixed and made into medicinal powder by above-mentioned weight ratio;
2) prepare gelatin solution: in 10kg water, add 2kg glycerine, stop heating after boiling, add 3kg gelatin and be stirred to and dissolve completely, for subsequent use;
3) medicinal powder 20kg, ginger powder 4kg, polyoxyethylene (PEO) 3kg and carbomer 1kg are added in stirrer, cover lid, stir evenly (about 5-10 minute);
4) glycerine 10kg is put into little stirrer, add after sodium polyacrylate 1kg is stirred to dispersion, add 8kg water, pour in step 3) gained mixture, stir evenly (10-15 minute, during stirring, need pressurization to cover tightly lid);
5) step 2 is then added) the middle gelatin solution prepared, stir into plasticity-material (20-25 minute, need pressurization to cover tightly lid during stirring);
6) sanitas is added: with 0.4kg dissolve with ethanol borneol 0.33kg, camphor 0.17kg, Tegosept M 0.08kg and ethyl p-hydroxybenzoate 0.08kg, add gained material in step 5);
7) heating solution is added: take ginger oil essence 0.17kg, paprika oleoresin 1.2kg, add gained material in step 6);
8) finally add Vaseline 5kg, be stirred to can flexible paste (", " sound occurring, ointment has mixed a piece, and rotten to the corn state occurs in surface), obtain flexible ointment;
9) described flexible ointment is handled as follows:
(1), described flexible ointment it is twisted into cylinder shape, utilizes tabletting machine to pull film that ointment is pressed into sheet;
(2), sheet ointment by punch die machine, pull mode by rushing a slice, make every sheet ointment be complete rectangle;
(3), often rush a slice and collect a slice, detect die-cut edge, pressure surface complete, measure weight;
(4), tablet tear thin film, the glue face not having film one side to be pasted onto back of the body glue, cover the back of the body and paste;
(5) tablet, good for the dress back of the body pasted loads aluminizes in interior bag, sealing, the compactness of detection sealing and smooth;
(6), every 10 bags with rubber circle binding, vanning, sealing, paste for one case 500
Wherein sheet ointment is cut into the fritter of 10 �� 15cm.
Embodiment 2
One is fallen dozen temperature and is pasted, and by weight, comprising:
Wherein, described medicinal powder comprises by weight:
Prepare above-mentioned falling and beat the warm method pasted, comprise the following steps:
1) by pulverizing medicinal materials, it is mixed and made into medicinal powder by above-mentioned weight ratio;
2) prepare gelatin solution: in 10kg water, add 2kg glycerine, stop heating after boiling, add 3kg gelatin and be stirred to and dissolve completely, for subsequent use;
3) medicinal powder 20kg, ginger powder 4kg, PEO3kg and carbomer 1kg are mixed;
4) after glycerine 10kg and sodium polyacrylate 1kg being stirred to dispersion, add 8kg water, pour in step 3) gained mixture, stir evenly;
5) step 2 is then added) the middle gelatin solution prepared, stir into plasticity-material;
6) sanitas is added: with 0.4kg dissolve with ethanol borneol 0.33kg, camphor 0.17kg, Tegosept M 0.08kg and ethyl p-hydroxybenzoate 0.08kg, add gained material in step 5);
7) heating solution is added: take ginger oil essence 0.17kg, paprika oleoresin 1.2kg, add gained material in step 6);
8) finally add Vaseline 5kg, it is stirred to flexible paste and namely obtains flexible ointment;
9) described flexible ointment is carried out following process:
1), described flexible ointment it is twisted into cylinder shape, utilizes tabletting machine to pull film that ointment is pressed into sheet;
2), sheet ointment by punch die machine, every sheet ointment is made to be complete rectangle;
3), tablet tear thin film, the glue face not having film one side to be pasted onto back of the body glue, cover the back of the body and paste;
4) tablet, good for the dress back of the body pasted loads aluminizes in interior bag, sealing.
Embodiment 3
Falling of the present invention is used to beat temperature subsides treatment patient, it may also be useful to method is: be affixed on affected part, and every day pastes once, and even applying 7 days was 1 course for the treatment of, judged curative effect after 1 course for the treatment of.
Wherein, total case 112 example of acute soft tissue sprain and contusion group, the age all 12-69 year, 36 years old mean age; Wherein Ankle joint sprain and contusion 40 example, shoulder joint sprain and contusion 34 example, shoulder joint sprain and contusion 38 example, treatment result is as shown in table 1.
Total case 101 example of chronic soft tissue sprain and contusion group, the age 25-69 year, average young 36 years old, all have chronic strain medical history. The shortest person of the course of disease 1 month, goes up person most 2 years; Wherein chronic ankle joint damage 32 example, scapulohumeral periarthritis 41 example, chronic knee damage 28 example, treatment result is as shown in table 2.
Table 1 the present invention falls dozen temperature and pastes the result for the treatment of to acute soft tissue sprain and contusion
Acute soft tissue sprain and contusion group 112 example, recovery from illness 71 example, accounts for 63.39%; Effective 21 examples, account for 18.75%; Effective 15 examples, account for 13.39%; Invalid 5 examples, account for 4.47%. Efficiency is always had to be 95.53.
Table 2 the present invention falls dozen temperature and pastes the result for the treatment of to chronic soft tissue sprain and contusion
Chronic soft tissue sprain and contusion group is totally 101 example, cures 63 examples, accounts for 62.37%; Effective 19 examples, account for 18.81%; Effective 15 examples, account for 14.85%; Invalid 4 examples, account for 3.96%. Efficiency is always had to be 96.04%.
As can be seen from Table 1 and Table 2, the present invention falls and beats temperature and paste and have acute and chronic soft tissue injuries are had good curative effect.
Claims (5)
1. one kind is fallen dozen temperature subsides, by weight, consists of the following composition:
Wherein, described medicinal powder consists of the following composition by weight:
2. prepare according to claim 1 falling and beat the warm method pasted, comprise the following steps:
1) medicinal material is pulverized respectively, it is mixed and made into medicinal powder by weight ratio according to claim 1;
2) prepare gelatin solution: in 10kg water, add 2kg glycerine, stop heating after boiling, add 3kg gelatin and be stirred to and dissolve completely, for subsequent use;
3) medicinal powder 20kg, ginger powder 4kg, polyoxyethylene 3kg and carbomer 1kg are mixed;
4), after glycerine 10kg and sodium polyacrylate 1kg being stirred to dispersion, add 8kg water, pour step 3 into) in gained mixture, stir evenly;
5) step 2 is then added) the middle gelatin solution prepared, stir into plasticity-material;
6) add sanitas: with 0.4kg dissolve with ethanol borneol 0.33kg, camphor 0.17kg, Tegosept M 0.08kg and ethyl p-hydroxybenzoate 0.08kg, add step 5) in gained material;
7) add heating solution: take ginger oil essence 0.17kg, paprika oleoresin 1.2kg, add step 6) in gained material;
8) finally add Vaseline 5kg, it is stirred to flexible paste and namely obtains flexible ointment.
3. the method beaten temperature and paste is fallen in preparation according to claim 2, further comprising the steps:
A, described flexible ointment is twisted into cylinder shape, utilizes tabletting machine to pull film that ointment is pressed into sheet;
B, sheet ointment by punch die machine, make every sheet ointment be complete rectangle;
C, tablet is torn thin film, the glue face not having film one side to be pasted onto back of the body glue, cover the back of the body and paste;
D, the tablet that good for the dress back of the body is pasted load aluminizes in interior bag, sealing.
4. method according to claim 2, it is characterised in that, in step 1) in will after described pulverizing medicinal materials cross 100 orders sieve.
5. fall, for the preparation of according to claim 1, the medicinal powder beaten temperature and paste, by weight, consist of the following composition:
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104383445A (en) * | 2014-11-26 | 2015-03-04 | 王艳萍 | Traumatic injury analgesic |
| CN104524080A (en) * | 2015-02-02 | 2015-04-22 | 范晓华 | Traditional Chinese medicine preparation for treating injuries from falls, fractures, contusions and strains and preparation method |
| CN104998221A (en) * | 2015-09-01 | 2015-10-28 | 蒙山县中医医院 | Chinese medicinal herb preparation for treating chronic pain and preparing method of Chinese medicinal herb preparation |
| CN107875224A (en) * | 2017-12-21 | 2018-04-06 | 苏州希尔盖森新材料有限公司 | A kind of spontaneous heating external application Traditional Chinese medicine used as analgesic composition and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101708258A (en) * | 2009-11-30 | 2010-05-19 | 郭洪勋 | Medicament for treating bone damage |
| CN103566313A (en) * | 2013-11-27 | 2014-02-12 | 陈燕 | External-application medicine for treating traumatic injuries |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101708258A (en) * | 2009-11-30 | 2010-05-19 | 郭洪勋 | Medicament for treating bone damage |
| CN103566313A (en) * | 2013-11-27 | 2014-02-12 | 陈燕 | External-application medicine for treating traumatic injuries |
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