CN103876840A - Optical-damage experimental device - Google Patents

Optical-damage experimental device Download PDF

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Publication number
CN103876840A
CN103876840A CN201310713279.3A CN201310713279A CN103876840A CN 103876840 A CN103876840 A CN 103876840A CN 201310713279 A CN201310713279 A CN 201310713279A CN 103876840 A CN103876840 A CN 103876840A
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China
Prior art keywords
experimental provision
support
framework
photic damage
damage experimental
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CN201310713279.3A
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CN103876840B (en
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刘庆淮
苏途
方圆
谢平
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Jiangsu Province Hospital
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Jiangsu Province Hospital
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Abstract

The invention provides an optical-damage experimental device comprising a support frame, a horizontal carrier and lamp screens. The support frame and the carrier are made of angle iron. The support frame is a cuboid framework formed by combination of stand columns and upper and low transverse frames. The horizontal carrier used for holding an animal experiment cage. An optical screen is arranged on the framework corresponding to at least one face of the animal experiment cage. The optical-damage experimental device is convenient to demount, illumination is uniform during experiment process, environment is good, operation is facilitated, and optical damage degree can be measured accurately.

Description

A kind of photic damage experimental provision
Technical field
The invention belongs to ophthalmology medical domain, be specifically related to a kind of for zoologizeing the photic damage experimental provision of retina photodamage experimental model.
Background technology
Retina is one of vital tissue structure of vision formation.Any extraneous light, only has the normally functioning retina of arrival could form certain visual pattern.If light is crossed weak or excessively strong, all cannot form visual pattern clearly.Therefore, appropriate light is very important to the formation of vision.On the contrary, if the time of the intensity of light, illumination etc. have exceeded amphiblestroid holding capacity, will cause amphiblestroid optical damage.Retina photodamage mechanism and control are important subject of field of ophthalmology always for many years, and wherein, the retina photodamage animal experiment device capable of setting up science is the emphasis of doctor and backroom boys's research always.Application number is 200920108782.5, and the Chinese patent that name is called " animal photo damage device " discloses a kind of a kind of animal photo damage device that discloses, and comprises lighttight box body, the animal of more than one lamp cylinder and printing opacity settles cylinder; The inwall of described lamp cylinder is evenly provided with the adjustable LED of illumination; Described lamp cylinder is located in box body; Described animal settles jacket casing to be located in lamp cylinder.There is following defect in said apparatus: 1. adopt LED lamp cylinder, there is no even tabula rasa, animal is subject to the light may be even not; 2. it is different from the daily feeding environment of animal that animal is settled the interior environment of cylinder, and in cylinder, an environment is difficult to cleaning; 3. cannot time switch light source and actual light intensity in measuring cylinder in time; 4. it is not clear that animal is settled cylinder and chest lucifuge and heat dispersion; Though 5.LED illumination scalable, LED lamp is changed trouble; 6. animal settles cylinder volume less, causes each light to expose size of animal few.Application number is 201220022980.1, the Chinese patent that name is called " retina photodamage experimental box " discloses a kind of retina photodamage experimental box, comprise the square box that length and width are equal, described box top is provided with the door of splitting, described casing left surface, right flank and trailing flank are provided with some louvres, the leading flank center of casing is provided with fan hole, in described fan hole, be embedded with fan, the inwall of described cabinet door, left surface inwall, right flank inwall and trailing flank inwall are equipped with respectively white daylight lamp, cabinets cavity is provided with some transparent grid screens inner chamber is separated into some points of cavitys.Adopt said apparatus, experiment is placed in each point of cavity of casing with rat, the rat in casing is carried out to strong radiation of visible light, the damage of induction rat retina with daylight lamp.There is following defect in above-mentioned experimental box: 1. be adopted as electric filament lamp, and even more serious compared with the source heat production of LED lamp; 2. space is comparatively airtight, animal activity inconvenience, animal feeding, clean environment inconvenience; 3. actual light intensity in measuring cylinder in time; 4. casing surrounding has louvre, and light-shading effect is not clear; 5. cannot time switch light source, the illumination experiment that cannot carry out that day alternates with night.
Summary of the invention
The present invention is directed to prior art deficiency, a kind of convenient disassembly is provided, illumination is even, and environment is good, easy to operate, the photic damage experimental provision that can accurately measure.
The concrete technical scheme of the present invention is as follows:
A kind of photic damage experimental provision, comprise support, horizontal tray and lamp screen, described support and horizontal tray are angle steel and make, support is the framework that column and upper lower horizontal border are combined into, framework is cuboid or cube, in framework, be provided with the horizontal tray for placing animal experimental cage, on framework corresponding at least one face of animal experimental cage, be provided with optical screen.
Above-mentioned photic damage experimental provision, optical screen can be fixed on the column or upper lower horizontal border of framework, staggered relatively with animal experimental cage face.
Above-mentioned photic damage experimental provision, horizontal tray is in state of the art, to disclose any structure of the present invention that is applicable to.Frame and supporting network that wherein a kind of structure can be made up of at least one pair of parallel support bar for bracket form, and the two ends of support bar are vertically fixed on the column of framework.Further, adopting under the situation of two pairs of parallel support bars, support bar forms " mouth " font and the equirotal parallel square frame of framework transverse frame.
A preferred version of above-mentioned photic damage experimental provision is the crossbeam that is respectively provided with pair of parallel on two horizontal pane faces up and down of described framework, and lower and upper cross-member is correspondence and aligned fashion one by one; At least one lamp screen is fixedly connected with crossbeam, and level or vertical distribution are between crossbeam.It is more easy, easy that this structure is installed optical screen.A further preferred version is that described horizontal tray is made up of in the bearing strip of crossbeam a pair of support bar and pair of parallel, the two ends of support bar are vertically fixed on the column of framework, the two ends of bearing strip are vertically fixed on respectively on two support bars, and the spacing of bearing strip is less than the spacing of two horizontal girds.Further can between the bearing strip of bracket, be provided with supporting network.When use, can, according to the bearing strip spacing of the size bracket of animal experimental cage, make bearing strip spacing be less than or equal to cage width, by the bearing strip that is positioned over horizontal tray of experimental cage.Regulate the spacing of framework horizontal pane face entablature simultaneously according to the size of experimental cage, make it to be greater than the width of experimental cage.In the hexahedro any one side of the solid towards animal experimental cage or multiple s' position, lamp screen is installed, lamp screen is fixed on crossbeam by bolt or band, can increase and decrease according to actual needs lamp screen quantity.
The supporting network of above-mentioned photic damage experimental provision is the grid that cross-coupled support bar forms hollow, can make animal experimental cage place more steady, and supporting network can be fixed on bearing strip by bolt or iron wire.
Above-mentioned photic damage experimental provision each several part material is angle steel, adopts dismountable connected mode, as bolt connects, and pin connection etc., further preferred angle steel with holes, without other punching, makes to install more easy when installation.
Above-mentioned photic damage experimental provision, lamp screen can be selected normal experiment lamp source used, preferably the LED optical screen of LED light source and even tabula rasa composition.
Above-mentioned photic damage experimental provision, also can, according to device internal temperature and requirement, freely install exhaust fan on support, reduces ambient temperature or aeration condition change exerts an influence to animal.
Above-mentioned photic damage experimental provision, its frame bottom can also be installed universal wheel, is convenient to mobile.
Above-mentioned photic damage experimental provision, also can be provided with illumination meter on its support, convenient monitoring intensity of illumination.
Above-mentioned photic damage experimental provision, is also provided with regular socket on its support, optical screen circuit, with regular socket link power supply, has countdown function, accurately light application time.
Above-mentioned photic damage experimental provision can use in the environment of lucifuge.
The present invention also provides a kind of photic damage experimental provision with lightshade cover, and the above-mentioned photic damage experimental provision with support, horizontal tray and optical screen is placed in to lightshade cover inside, is convenient to test having in luminous environment.The cover of lightshade cover selects conduction of heat express delivery metal to make, and is preferably venetian blind type, and blade openings upward.Both met the requirement of experiment lucifuge, and increased again ventilation effect in lighting box, environment can not cause light pollution yet to external world.Support, horizontal tray and lightshade cover inside are black frosted coating, avoid source reflection.
Advantage of the present invention:
1. photic damage experimental provision of the present invention, support and bracket use angle steel with holes, can arbitrarily regulate bearing strip position, lamp screen position and lamp screen quantity according to the size of laboratory animal cage, flexible, are suitable for the requirement of different experiments;
2. what the present invention adopted is that LED light source adds even tabula rasa formation LED screen, luminous more even, can select stepless regulated type LED lamp screen of all kinds according to experiment light intensity;
3. the present invention can increase and decrease provided with fan as required, reduces ambient temperature or aeration condition and changes animal is exerted an influence;
4. universal wheel can also be installed in apparatus of the present invention bottom, is convenient to mobile;
5. apparatus of the present invention inner space is large, can place laboratory animal by whole cage, and feeding environment is identical on ordinary days with animal;
In LED of the present invention screen circuit with regular socket link power supply, there is countdown function, accurately light application time, accurately carries out periodicity illumination experiment;
7. apparatus of the present invention also can be provided with illumination meter, convenient monitoring intensity of illumination;
8. the lightshade cover surrounding tank wall that apparatus of the present invention are selected is shutter, blade openings upwards, this design increases radiating effect, be beneficial to the circulation of case inner air and outer air, and avoid extraneous light to disturb, lucifuge and circulation of air performance are good, and support, horizontal tray and lightshade cover inside are black frosted coating, avoid source reflection.
Accompanying drawing explanation
Fig. 1 is the main structure schematic diagram of photo-damage device of the present invention;
Fig. 2 is the top view of photo-damage device of the present invention;
Fig. 3 is the schematic diagram of lightshade cover of the present invention;
In attached Fig. 1 and 2: 1-support, 2-horizontal tray, 3-LED lamp screen, 4-crossbeam, 5-bearing strip, 6-animal experimental cage, 7-universal wheel.
The specific embodiment
Concrete steps of the present invention are described by the following examples, but not limited by embodiment.
The term that used in the present invention, except as otherwise noted, generally has the implication that those of ordinary skills understand conventionally.
Below in conjunction with specific embodiment comparable data, the present invention is described in further detail.Should be understood that these embodiment just in order to demonstrate the invention, but not limit the scope of the invention by any way.
Embodiment 1
A kind of photic damage experimental provision, its main structure schematic diagram as shown in Figure 1, Fig. 2 is the top view of Fig. 1, comprise support 1, horizontal tray 2 and LED lamp screen 3, described support 1 and horizontal tray 2 are angle steel with holes and make, and support 1 is the framework that column and upper lower horizontal border are combined into, and framework is cuboid, the crossbeam 4 that is also respectively provided with pair of parallel on two horizontal pane faces up and down of framework, lower and upper cross-member is correspondence and aligned fashion one by one; At least one lamp screen 3 is fixedly connected with crossbeam 4, and level or vertical distribution are between crossbeam 4; Horizontal tray 2 is housed in framework, horizontal tray 2 is made up of in the bearing strip 5 of crossbeam a pair of support bar and pair of parallel, the two ends of support bar are vertically fixed on the column of framework, the two ends of bearing strip 5 are vertically fixed on respectively on two support bars, and the spacing of bearing strip 5 is less than the spacing of two horizontal girds 4.
Above-mentioned photic damage experimental provision each several part material mode with bolts, is convenient to carry out in order to adapt to different animal experimental cages in dismounting and use procedure the adjustment of size and distance.Further has installed triangular plate and has reinforced at the drift angle place of support and horizontal tray frame face.Meanwhile, between the bearing strip of bracket, increase and fixed a supporting network, supporting network is the wire side that is formed hollow by cross-coupled support bar, animal experimental cage is placed more steady.Frame bottom can also be installed universal wheel 7, is convenient to mobile.
When use, can regulate according to the size of animal experimental cage 6 bearing strip 5 spacing of horizontal tray 2, make bearing strip 5 spacing be less than or equal to cage width, by the bearing strip that is positioned over horizontal tray 25 of experimental cage.Regulate the spacing of framework horizontal pane face entablature 4 simultaneously according to the size of experimental cage, make it to be greater than the width of experimental cage.At the hexahedro any one side of the solid towards animal experimental cage or multiple s' position mounted LED lamp screen 3, LED lamp screen 3 is fixed on crossbeam by bolt or band, can increase and decrease according to actual needs LED lamp and shield 3 quantity.
Can be on above-mentioned photic damage experimental provision architecture basics, support 1 is set up to exhaust fan, illumination meter and regular socket, make this photic damage experimental provision not only can reduce ambient temperature or aeration condition change to animal exert an influence, convenient monitoring intensity of illumination and accurate light application time, accurately carry out periodicity illumination experiment.
Meanwhile, lightshade cover 8 in whole support outer cup, as shown in Figure 3, the cover of lightshade cover 8 is venetian blind type, and blade is outwards opening up, and support 1 and lightshade cover 8 are inner with black frosted coating.This design increases radiating effect, is beneficial to the circulation of case inner air and outer air, and avoids extraneous light to disturb, and lucifuge and circulation of air performance are good, and support 1, horizontal tray 2 and lightshade cover 8 inside are black frosted coating, avoid source reflection.

Claims (10)

1. a photic damage experimental provision, it is characterized in that comprising support, horizontal tray and lamp screen, described support and bracket are angle steel and make, support is the framework that column and upper lower horizontal border are combined into, framework is cuboid or cube, in framework, be provided with the horizontal tray for placing animal experimental cage, on framework corresponding at least one face of animal experimental cage, be provided with optical screen.
2. photic damage experimental provision as claimed in claim 1, is characterized in that frame and supporting network that described horizontal tray is made up of at least one pair of support bar form, and the two ends of support bar are vertically fixed on the column of framework.
3. photic damage experimental provision as claimed in claim 1, is characterized in that being respectively provided with on two horizontal pane faces up and down of described framework the crossbeam of pair of parallel, and lower and upper cross-member is correspondence and aligned fashion one by one; At least one lamp screen is fixedly connected with crossbeam, and level or vertical distribution are between crossbeam.
4. photic damage experimental provision as claimed in claim 3, it is characterized in that described horizontal tray is made up of in the bearing strip of crossbeam a pair of support bar and pair of parallel, the two ends of support bar are vertically fixed on the column of framework, the two ends of bearing strip are vertically fixed on respectively on two support bars, and the spacing of bearing strip is less than the spacing of two horizontal girds.
5. photic damage experimental provision as claimed in claim 4, is characterized in that being provided with supporting network between the bearing strip of described horizontal tray.
6. the photic damage experimental provision as described in claim 1 any one, also install triangular plate and reinforce at the drift angle place that it is characterized in that described support and/or horizontal tray frame face.
7. the photic damage experimental provision as described in claim 1 any one, is characterized in that described lamp screen is made up of LED light source and even tabula rasa.
8. the photic damage experimental provision as described in claim 1 any one, is characterized in that being also provided with on described support one or more parts in exhaust fan, universal wheel, illumination meter, regular socket.
9. the photic damage experimental provision as described in claim 1-8 any one, is characterized in that described device also comprises lightshade cover, covers in inside by support.
10. photic damage experimental provision as claimed in claim 9, the cover that it is characterized in that described lightshade cover is venetian blind type, upward, described support and lightshade cover are inner with black frosted coating for blade openings.
CN201310713279.3A 2013-12-20 2013-12-20 A kind of photic damage experimental provision Active CN103876840B (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104361806A (en) * 2014-11-10 2015-02-18 辽宁石油化工大学 Teaching demonstration device for light penetrating force experiment
CN105156954A (en) * 2015-10-09 2015-12-16 中国科学院西北高原生物研究所 Light irradiation device used for establishment of experimental animal skin injury model
CN105675609A (en) * 2016-01-19 2016-06-15 北京阳明智道光电科技有限公司 Measuring device and quantitative assessment method of retinal photic injury
CN109006512A (en) * 2018-07-06 2018-12-18 西安医学院 A kind of experimental optical damage animal model construction device
CN113841621A (en) * 2021-09-28 2021-12-28 上海市第一人民医院 Experimental blue light-induced retinal light injury model device

Citations (5)

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Publication number Priority date Publication date Assignee Title
US5194041A (en) * 1991-08-05 1993-03-16 Standard Safety Equipment Co. Ventilation system for isolators
CN201492408U (en) * 2009-06-17 2010-06-02 北京大学第三医院 Animal photo damage device
CN202446290U (en) * 2012-01-18 2012-09-26 江苏省苏北人民医院 Retinal light injury experiment box
CN103211581A (en) * 2013-04-19 2013-07-24 温州医学院 Temperature-and-illumination-controllable type retinal photo-injury quantitative research device
CN203634291U (en) * 2013-12-20 2014-06-11 江苏省人民医院 Light injury experiment apparatus

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194041A (en) * 1991-08-05 1993-03-16 Standard Safety Equipment Co. Ventilation system for isolators
CN201492408U (en) * 2009-06-17 2010-06-02 北京大学第三医院 Animal photo damage device
CN202446290U (en) * 2012-01-18 2012-09-26 江苏省苏北人民医院 Retinal light injury experiment box
CN103211581A (en) * 2013-04-19 2013-07-24 温州医学院 Temperature-and-illumination-controllable type retinal photo-injury quantitative research device
CN203634291U (en) * 2013-12-20 2014-06-11 江苏省人民医院 Light injury experiment apparatus

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104361806A (en) * 2014-11-10 2015-02-18 辽宁石油化工大学 Teaching demonstration device for light penetrating force experiment
CN104361806B (en) * 2014-11-10 2018-02-09 辽宁石油化工大学 A kind of teaching demonstration device of light penetration power experiment
CN105156954A (en) * 2015-10-09 2015-12-16 中国科学院西北高原生物研究所 Light irradiation device used for establishment of experimental animal skin injury model
CN105675609A (en) * 2016-01-19 2016-06-15 北京阳明智道光电科技有限公司 Measuring device and quantitative assessment method of retinal photic injury
CN105675609B (en) * 2016-01-19 2018-03-20 北京阳明智道光电科技有限公司 A kind of retinal light damage measurement apparatus and quantitative evaluation method
CN109006512A (en) * 2018-07-06 2018-12-18 西安医学院 A kind of experimental optical damage animal model construction device
CN113841621A (en) * 2021-09-28 2021-12-28 上海市第一人民医院 Experimental blue light-induced retinal light injury model device

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Inventor after: Xie Ping

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Inventor after: Su Tu

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