CN103860827A - Traditional Chinese medicine preparation for treating migraine - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for treating migraine. The modern medical science thinks that the migraine is a severe headache caused by intracranial vascular dysfunction, blood disorders, and tired and pain nerve fibers, belongs to the domains of 'headache', 'migraine' and the like in the traditional Chinese medicine. Therefore, the traditional Chinese medicines: namely octagonal lotus, rhizoma tupistrae chinensis, intermediate peashrub flower, hairyvein agrimony, curious kadsura root stem, fructus citri, alpine swertia, viola muehldorfii, tuber fleeceflower stem, kweichow sage herb, and liquorice are selected to be decocted into soup by a manufacturing laboratory in a hospital. A clinical test proves that the significant efficiency on the migraine is 73.8%, the total effective rate is 96.2%, and the traditional Chinese medicine preparation is small in toxic and side effects.

Description

One is treated migrainous Chinese medicine preparation

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to one and treat migrainous Chinese medicine preparation.

Background technology

Migraine is one of common clinical disease, is the common sympton of department of neurology, and the cause of disease is a lot, comprises tens kinds of intracranial, cranium diseases, all over the body etc. outward.Migraine is the one of vascular headache, and primary disease is that sickness rate is higher, is about 5% due to the disorderly caused syndrome of the outer tremulous pulse systolic and diastolic function of intracranial.Age of onset was at 14 years old-48 years old, and female is slightly more than man.Take a side frontal temporal part pain as its feature, aggravate as main take jumping pain, severe pain or paroxysmal; Often break out, generally continue 4h-72h, seldom exceed 72 hours; Mostly be unilateral headache, bilateral headache incidence rate is lower, accounts for 25%～60%; Its morbidity and inherited genetic factors, the factors such as Nervous and Mental Factors, endocrine factors and diet are relevant, and it is nervous, worried that risk factor mostly is, fatigue, flu or wound.Find through clinical experience in recent years, Chinese medicine has good curative effect aspect treatment migraine.

Summary of the invention

The object of this invention is to provide one and treat migrainous Chinese medicine preparation.Modern medicine thinks, migraine is the intracranial vessel dysfunction of releiving, and blood obstacle involves pain sensation fiber nerve and the severe headache that causes.Belong to the categories such as motherland's medical science " headache ", " migraine ".

The object of the invention is to be achieved through the following technical solutions, the migrainous Chinese medicine preparation of this treatment is made up of the Chinese medicine of following weight portion: 15-20 parts of dysosma auranticocaulis (Hand. Mazz.) Hus, 10-15 parts of Rhizoma Tupistrae Chinensis, 16-22 parts of Flos Caraganae intermediaes, 20-25 parts of Herba Agrimoniaes, 9-17 parts of Radix seu Caulis Kadsurae Heteroclitae, 5-8 parts of Fructus Citris, 13-18 parts of Herba Swertiae heteranthaes, 4-8 parts of Radix violae delavayis, 15-25 parts of Caulis Polygoni Multiflori, 25-30 parts of Herba Salviae Cavaleriei, 4-6 parts, Radix Glycyrrhizae.

Preferably, 18 parts of dysosma auranticocaulis (Hand. Mazz.) Hus, 13 parts of Rhizoma Tupistrae Chinensis, 19 parts of Flos Caraganae intermediaes, 23 parts of Herba Agrimoniaes, 13 parts of Radix seu Caulis Kadsurae Heteroclitae, 6.5 parts of Fructus Citris, 16 parts of Herba Swertiae heteranthaes, 6 parts of Radix violae delavayis, 20 parts of Caulis Polygoni Multiflori, 27 parts of Herba Salviae Cavaleriei, 5 parts, Radix Glycyrrhizae.

Preparation method is made decoction by traditional method by above-mentioned Chinese medicine decocting.

In side: dysosma auranticocaulis (Hand. Mazz.) Hu, Rhizoma Tupistrae Chinensis, Flos Caraganae intermediae, Herba Agrimoniae eliminating stagnation are invigorated blood circulation, reducing swelling and alleviating pain, removing toxic substances heat clearing away, nourishing yin and purging fire, nourishing blood to tranquillize the mind; Radix seu Caulis Kadsurae Heteroclitae: expelling wind and removing dampness, promoting flow of QI and blood; Fructus Citri, Herba Swertiae heteranthae dispersing the stagnated live-QI to relieve the stagnation of QI regulating the flow of QI to ease the stomach, suppressing the hyperactive liver to relieve the wind syndrome, heart tonifying nourishes blood; Radix violae delavayi, Caulis Polygoni Multiflori removing obstruction in the collateral to relieve pain, tranquilizing by nourishing the heart; Herba Salviae Cavaleriei: hemostasis removing heat from blood; Radix Glycyrrhizae QI invigorating invigorating middle warmer heat-clearing and toxic substances removing, alleviates pain relieving, the mediation property of medicine.

Clinical data

1, physical data 130 examples my Out-patient Department of all serving as reasons is diagnosed as the patient of " migraine ", wherein male 55 examples, female's 75 examples; Age of onset 20～75 years old; The shortest person of the course of disease 2 days, elder 20 years.All cases is all got rid of due to organic disease and is had a headache through cranium brain CT or the inspection of cranium brain magnetic resonance imaging before treatment, and before and after treatment, does " rheoencephalogram " and " through cranium color Doppler " and check with observe the curative effect.Inducement person 29 examples relevant to menstrual cycle, the person's of overworking 50 examples, feelings will impassable patient 36 examples, without obvious inducement person's 15 examples.

2, the headache of diagnostic criteria repeated relapsing, the intermission is completely normal, gets rid of the headache that other organic diseases cause; Possess in following 63 diagnosable: 1. when headache outbreak with feeling sick, vomiting, time or have ictal stomachache; 2. side headache partially; 3. pulsatile headache; 4. short-term is had a rest or the rear alleviation of sleep; 5. visual abnormality; 6. there is migrainous family history.

3 this group of Therapeutic Method patients take Chinese medicine preparation of the present invention, take dysosma auranticocaulis (Hand. Mazz.) Hu 18g, Rhizoma Tupistrae Chinensis 13g, 19 parts of Flos Caraganae intermediaes, Herba Agrimoniae 23g, Radix seu Caulis Kadsurae Heteroclitae 13g, Fructus Citri 6.5g, Herba Swertiae heteranthae 16g, Radix violae delavayi 6g, Caulis Polygoni Multiflori 20g, Herba Salviae Cavaleriei 27g, Radix Glycyrrhizae 5g, make decoction by traditional method decocting, 1 dose of every day, early, evening 2 sub-services, within 7 days, be a course for the treatment of.

4, efficacy assessment standard: the curative effect after (1) treatment.Effective: transference cure, rheoencephalogram, the inspection of cranium brain color Doppler recover normal, follow up a case by regular visits to not recurrence in 2 years; Effective: transference cure, rheoencephalogram, the inspection of cranium brain color Doppler still have extremely, follow up a case by regular visits in 2 years and still have outbreak, and attack times reduces 2/3, and the symptom of outbreak obviously alleviates before; Invalid: though symptom alleviates to some extent, attack times does not subtract, rheoencephalogram, cranium brain color Doppler check without improving.

5, therapeutic outcome (1) this group patient treatment is added up curative effect after 3 courses for the treatment of, wherein effective: 96 examples (73.8%); Effective: 29 examples (22.3%); Invalid: 5 examples (3.8%); Total effective rate reaches 96.2%.

(2) cerebral blood flow index comparison before and after treatment.After middle cerebral artery (MCA), the treatment of anterior cerebral artery (ACA) flow velocity, all there is obvious reduction.See the following form 1.

Cerebral blood flow index comparison before and after table 1. treatment (cm/s, x ± s)

5, model case Lee so-and-so, female, 30 years old, office worker.Calendar year 2001 first visit on June 20.Migraine 7 years, through integrative therapy poor effect for many years.Recently headache outbreak is frequent, shows effect weekly 2～4 times, and has poor, vexed, the irritability of sleep, has hypochondriac pain, bitter taste, flushing concurrently, red tongue, yellow and thin fur, stringy pulse, and inappetence, is diagnosed as migraine.Take Chinese medicine preparation of the present invention, 7 doses.15 days 2 January in 2010 examines, and patient's headache alleviates, sleep improvement.Appetite increases, and examines its light red tongue, slightly string of white and thin fur, moderate pulse.3 doses of following the services.10 days 3 February in 2010 examines, and patient states headache heals, and other simultaneous phenomenon disappears, and follows up a case by regular visits to 2 years, does not recur again.

The specific embodiment

Embodiment mono-: take dysosma auranticocaulis (Hand. Mazz.) Hu 18g, Rhizoma Tupistrae Chinensis 13g, 19 parts of Flos Caraganae intermediaes, Herba Agrimoniae 23g, Radix seu Caulis Kadsurae Heteroclitae 13g, Fructus Citri 6.5g, Herba Swertiae heteranthae 16g, Radix violae delavayi 6g, Caulis Polygoni Multiflori 20g, Herba Salviae Cavaleriei 27g, Radix Glycyrrhizae 5g, become decoction by traditional preparation method decocting.

Embodiment bis-: take dysosma auranticocaulis (Hand. Mazz.) Hu 20g, Rhizoma Tupistrae Chinensis 15g, 22 parts of Flos Caraganae intermediaes, Herba Agrimoniae 25g, Radix seu Caulis Kadsurae Heteroclitae 17g, Fructus Citri 8g, Herba Swertiae heteranthae 13g, Radix violae delavayi 8g, Caulis Polygoni Multiflori 25g, Herba Salviae Cavaleriei 30g, Radix Glycyrrhizae 6g, become decoction by traditional preparation method decocting.

Embodiment tri-: take dysosma auranticocaulis (Hand. Mazz.) Hu 15g, Rhizoma Tupistrae Chinensis 10g, 16 parts of Flos Caraganae intermediaes, Herba Agrimoniae 20g, Radix seu Caulis Kadsurae Heteroclitae 9g, Fructus Citri 5g, Herba Swertiae heteranthae 18g, Radix violae delavayi 4g, Caulis Polygoni Multiflori 15g, Herba Salviae Cavaleriei 25g, Radix Glycyrrhizae 4g, become decoction by traditional preparation method decocting.

Claims (2)

1. the migrainous Chinese medicine preparation for the treatment of, is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of lower weight portion: 15-20 parts of dysosma auranticocaulis (Hand. Mazz.) Hus, Rhizoma Tupistrae Chinensis 10-15 part, 16-22 parts of Flos Caraganae intermediaes, 20-25 parts of Herba Agrimoniaes, 9-17 parts of Radix seu Caulis Kadsurae Heteroclitae, 5-8 parts of Fructus Citris, 13-18 parts of Herba Swertiae heteranthaes, 4-8 parts of Radix violae delavayis, 15-25 parts of Caulis Polygoni Multiflori, 25-30 parts of Herba Salviae Cavaleriei, 4-6 parts, Radix Glycyrrhizae.

2. one according to claim 1 is treated migrainous Chinese medicine preparation, it is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: 18 parts of dysosma auranticocaulis (Hand. Mazz.) Hus, 13 parts of Rhizoma Tupistrae Chinensis, 19 parts of Flos Caraganae intermediaes, 23 parts of Herba Agrimoniaes, 13 parts of Radix seu Caulis Kadsurae Heteroclitae, 6 parts of 16 parts of Radix violae delavayis of 6.5 parts of Herba Swertiae heteranthaes of Fructus Citri, 20 parts of Caulis Polygoni Multiflori, 27 parts of Herba Salviae Cavaleriei, 5 parts, Radix Glycyrrhizae.