CN103860293A - Individualized reversal design and manufacturing method for full knee joint replacing prosthesis - Google Patents
Individualized reversal design and manufacturing method for full knee joint replacing prosthesis Download PDFInfo
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- CN103860293A CN103860293A CN201410081733.2A CN201410081733A CN103860293A CN 103860293 A CN103860293 A CN 103860293A CN 201410081733 A CN201410081733 A CN 201410081733A CN 103860293 A CN103860293 A CN 103860293A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/38—Joints for elbows or knees
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
Abstract
The invention relates to an individualized reversal design and manufacturing method for a full knee joint replacing prosthesis. The method comprises the following steps that 1, three-dimensional digital models of the thighbone and the tibia are built on the basis of the medical image data of the knee joint of a patient; 2, virtual bone cutting software is used for respectively carrying out simulated bone cutting on the three-dimensional digital models of the thighbone and the tibia; 3, the reversal design of CAD (computer-aided design) models of a thighbone replacing prosthesis, a tibia replacing prosthesis and a tibia gasket prosthesis is carried out; 4, the full knee joint replacing prosthesis is manufactured according to the CAD models of each prosthesis through the 3D (three-dimensional) printing technology. The method provided by the invention has the advantages that on the basis of the original bone structure of the patient, the virtual knee joint replacing operation bone cutting form is combined, the structural form of the replacing prosthesis is subjected to reversal design, the structural form consistency of the cut bone and the replacing implanted body structure is realized to the greatest degree, and the optimum matching between the prosthesis and the individual bone form is reached. In addition, the laser selective melting 3D printing technology is used for manufacturing the designed replacing prosthesis, the optimum matching between the prosthesis and the knee joint bone cutting surface is ensured on the basis of the minimum bone cutting quantity, and the effect optimization is reached.
Description
Technical field
The present invention relates to a kind of design and manufacture method of artificial knee joint prosthesis, be specifically related to a kind of personalized reversal design and manufacture method based on former bone growth promoting form full knee joint transposing prosthesis.
Background technology
At present, osteoarthritis, rheumatoid arthritis are the common joint diseases of old people, have a strong impact on patient's quality of life, lack effective expectant treatment method.For the patient of osteoarthritis in late period, total knee replacement has been widely used in clinical now, becomes effective Therapeutic Method of this type of disease for the treatment of, can alleviate patient's slight illness, improves the quality of living.
The knee-joint anatomy form that studies show that each individual patients is different, and at present full knee replacement is all the prosthese of several different models of standardization, modularized design with knee joint prosthesis system, standardized like this prosthese and patient individual's knee joint morphology just there will be and not mate.Prosthese and knee joint morphology do not mate and can cause the covering of prosthese complete or hang, so cause prosthese wearing and tearing, service life shortens and the clinical symptoms such as joint replacement patella pain, swelling, the possibility that even causes prosthese to overhaul.Therefore be necessary to design the prosthese that reaches optimum matching with knee joint morphology, improve surgical effect, reduce complication.This just need to manufacture and design personalized knee-joint prosthesis for each patient.But existing knee-joint prosthesis process technology generally adopts the method such as die casting, numerical control polish, cannot realize the personalized designs and customization processing and manufacturing of knee-joint prosthesis.
Laser selective melting technology is as a kind of New Processing, and development reaches its maturity, and has been verified and can be successfully applied to biomedical manufacture field.It adopts laser high-temperature heating to make the mode that in constituency, material melts completely, successively piles up entity component, can accurate forming parts with complex structures, and forming part dense structure, precision are high.Utilize the novel manufacturing method of laser selective melting technology as knee-joint prosthesis, will break knee-joint prosthesis traditional moulds forging type, realize the personalized processing and manufacturing of knee-joint prosthesis.
Summary of the invention
For the problems referred to above, the object of this invention is to provide a kind of personalized reversal design and manufacture method based on former bone growth promoting form full knee joint transposing prosthesis.
For achieving the above object, the present invention takes following technical scheme: a kind of personalized reversal design and manufacture method of full knee joint transposing prosthesis, it is characterized in that, and comprising:
1) set up the step of femur and tibia three-dimensional digitalization model based on the kneed medical image data of patient;
2) use virtual osteotomy software respectively femur and tibia three-dimensional digitalization model to be simulated the step of osteotomy;
3) step of the cad model of reversal design femur replacement prosthesis, tibia replacement prosthesis and tibial insert prosthese;
4) according to the cad model of above-mentioned each prosthese and manufacture the step of total knee replacement vacation by 3D printing technique.
Described step 1) specifically comprises: the 1. CT/MRI tomoscan image of the DICOM form based on patient's knee joint femur, use medical image software Mimics, the feature that shows different gray scales according to soft tissue from skeleton in image carries out that image is cut apart, after repairing treatment, carry out three-dimensionalreconstruction to obtain femur three-dimensional digitalization model, and be output as PLY formatted file; 2. the CT/MRI tomoscan image of the DICOM form based on patient's knee joint tibia, use medical image software Mimics, the feature that shows different gray scales according to soft tissue from skeleton in image carries out that image is cut apart, after repairing treatment, carry out three-dimensionalreconstruction to obtain tibia three-dimensional digitalization model, and be output as PLY formatted file.
Described step 2) specifically comprise: 1. the PLY formatted file of femur three-dimensional digitalization model is imported to Geomagic Studio software, the mechanical axis of model femur, then on the vertical of mechanical axis, find the surgery epicondyle line of femur, take femur mechanical axis as Z axis, surgery epicondyle line is X-axis, sets up three-dimensional system of coordinate according to right-handed Cartesian coordinate system rule; Complete behind the location of femur, simulate distal femur osteotomy according to the operation plan of total knee replacement, obtain the amputation bone model of femur and retain bone model, export as STL formatted file; 2. the PLY formatted file of tibia three-dimensional digitalization model is imported to Geomagic Studio software, the mechanical axis of model tibia, then take tibia mechanical axis as Z axis, surgery epicondyle line is X-axis, sets up three-dimensional system of coordinate according to right-handed Cartesian coordinate system rule; Complete behind the location of tibia, by 7 ° of tibia hypsokinesis, under Lateral tibial plateau, 10mm simulates proximal tibia osteotomy, obtains the amputation bone model of tibia and retains bone model, exports as STL formatted file.
Described step 3) specifically comprises: 1., first according to the amputation bone model of femur, extract distal femur curved-surface shape, keep constant fairing and optimization, the acquisition femoral prosthesis curved-surface shape of carrying out of distal femur curved-surface shape; Then according to the reservation bone model of femur, extract osteotomy and retain surface of bone configuration of surface feature, design femoral prosthesis binding face feature; Finally add fixed structure, comprise and add stationary cylinder and rear end connection cylinder, obtain final femur replacement prosthesis cad model; 2. according to the reservation bone model of tibia, extract osteotomy and retain surface of bone configuration of surface feature, design tibial prosthesis binding face feature; Then hammer into thing with the design of tibial bone pulp cavity pattern, obtain final tibia replacement prosthesis cad model; 3. obtain the basic configuration of tibial insert prosthese according to femur replacement prosthesis curved surface and tibia amputation bone model, the morphological characteristic of design tibial insert, make itself and femoral prosthesis curved surface and tibial prosthesis structure optimum matching, obtain final tibial insert prosthese cad model.
Described step 4) specifically comprises: 1. the cad model of femur replacement prosthesis, tibia replacement prosthesis and tibial insert prosthese is imported in rapid shaping assistant software MaterialiseMagics and processed, comprise and put location, interpolation support and layering, and the hierarchical file obtaining is saved as to CLI form; 2. hierarchical file is imported to the setting of carrying out scan mode selection and sweep span in RPPath software, obtain importing to rapid prototyping system after two-dimension data, pass into noble gas, the 3D that carries out laser selective melting prints and manufactures; 3. take out femur replacement prosthesis, tibia replacement prosthesis and tibial insert prosthese test specimen that 3D prints, implement the operation of subsequent heat treatment, sandblast and polishing, complete the manufacture of full knee joint transposing prosthesis finished product.
The step of described step 4) 2. in, the 3D of laser selective melting prints to manufacture and is specially: flexible Pu Fen mechanism is entirely laid on powder on substrate, then laser scans according to the two-dimension data after model layering under computer control, after powder smelting, condense on lower one deck matrix, then moulding cylinder decline powder cylinder rises, the powder feeding again of paving powder system, paving powder, melting powder, repeat this process, until manufactured.
In a preferred embodiment, it is orthogonal scanning that 3D prints the scan mode of manufacturing, and sweep span is set to 0.08mm, processing bed thickness 0.035mm, scanning speed 700mm/s, laser power 160W.
In a preferred embodiment, noble gas is nitrogen or argon.
In a preferred embodiment, the manufactured materials of femur replacement prosthesis and tibia replacement prosthesis is selected biomedical cochrome powder or titanium alloy powder.
In a preferred embodiment, the manufactured materials of tibial insert prosthese is selected biomedical ultra-high molecular weight polyethylene powder.
The present invention is owing to taking above technical scheme, and it has the following advantages: 1, the present invention proposes the personalized reversal design thinking of a kind of full endoprosthetic knee based on former bone growth promoting form.It is on patient's knee joint morphology architecture basics, combined with virtual replacement knee in arthroplasty osteotomy form (comprise amputation bone and retain bone form), displacement borrowed structure form is carried out to reversal design, farthest realize amputation bone and replace the consistent of implant configuration, reaching the optimum matching of prosthese and individual bone form.2, another advantage of the present invention is to determine according to patient individual's knee joint morphology the deep strategy of each several part, reaches the requirement of excision sufferer structure and minimum deep amount.3, the present invention adopts 3D printing technique to manufacture full knee joint transposing prosthesis, break standardization formulation, turned over the unfavorable factors such as the precision that the technique such as die cast, mechanical process has is not high, the process-cycle is grown, involve great expense, start out a kind of novel medical science and manufacture field, not only be applicable to processed complex constitutional detail, and the process-cycle is short, individual character fit is high, and the personalization that is applicable to very much small lot is customized, and also demonstrating personalization becomes the feasibility of following artificial prosthesis developing direction.Therefore, adopt laser selective melting 3D printing technique manufacture full knee joint transposing prosthesis to solve a difficult problem for individual character manufacturing, can on the basis of personalized designs, produce the full knee joint transposing prosthesis with patient's knee joint morphology optimum matching, thereby realize the optimum matching that guarantees prosthese and knee joint osteotomy surface on the basis of minimum deep amount, optimization is effective.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, the present invention is carried out to detailed describing.But only the providing in order to understand better the present invention of accompanying drawing is provided, they not should be understood to limitation of the present invention.
Fig. 1 is schematic flow sheet of the present invention;
Fig. 2 is the primary femur aspect graph of patient;
Fig. 3 is the primary tibia aspect graph of patient;
Fig. 4 is that after osteotomy, femur retains bone figure;
Fig. 5 is femur amputation bone figure after osteotomy;
Fig. 6 is that osteotomy ossa tibiale posterius retains bone figure;
Fig. 7 is osteotomy ossa tibiale posterius amputation bone figure;
Fig. 8 is the femoral prosthesis schematic diagram that designs a model;
Fig. 9 is the tibial prosthesis schematic diagram that designs a model;
Figure 10 is the tibial insert schematic diagram that designs a model;
Figure 11 is that knee-joint prosthesis 3D of the present invention manufactures layering schematic diagram.
The specific embodiment
Below in conjunction with drawings and Examples, the present invention is described in detail.
As shown in Figure 1, personalized reversal design and the manufacture method of full knee joint transposing prosthesis provided by the invention comprise the following steps:
1, set up femur and tibia three-dimensional digitalization model based on the kneed medical image data of patient:
1) the CT/MRI tomoscan image of the DICOM form based on patient's knee joint femur, use medical image software Mimics, the feature that shows different gray scales according to soft tissue from skeleton in image carries out that image is cut apart, after repairing treatment, carry out three-dimensionalreconstruction to obtain femur three-dimensional digitalization model (as shown in Figure 2), and be output as PLY formatted file.
2) the CT/MRI tomoscan image of the DICOM form based on patient's knee joint tibia, use medical image software Mimics, the feature that shows different gray scales according to soft tissue from skeleton in image carries out that image is cut apart, after repairing treatment, carry out three-dimensionalreconstruction to obtain tibia three-dimensional digitalization model (as shown in Figure 3), and be output as PLY formatted file.
2, use virtual osteotomy software respectively femur and tibia three-dimensional digitalization model to be simulated to osteotomy:
1) the PLY formatted file of femur three-dimensional digitalization model is imported to Geomagic Studio software, the mechanical axis of model femur, then on the vertical of mechanical axis, find the surgery epicondyle line of femur, take femur mechanical axis as Z axis, surgery epicondyle line is X-axis, sets up three-dimensional system of coordinate according to right-handed Cartesian coordinate system rule; Complete behind the location of femur, simulate distal femur osteotomy according to the operation plan of total knee replacement, obtain the amputation bone model (as shown in Figure 5) of femur and retain bone model (as shown in Figure 4), export as STL formatted file.
2) the PLY formatted file of tibia three-dimensional digitalization model is imported to Geomagic Studio software, the mechanical axis of model tibia, then take tibia mechanical axis as Z axis, surgery epicondyle line is X-axis, sets up three-dimensional system of coordinate according to right-handed Cartesian coordinate system rule; Complete behind the location of tibia, by 7 ° of tibia hypsokinesis, under Lateral tibial plateau, (fibula side) 10mm simulates proximal tibia osteotomy, obtains the amputation bone model (as shown in Figure 7) of tibia and retains bone model (as shown in Figure 6), exports as STL formatted file.
3, the cad model of reversal design femur replacement prosthesis, tibia replacement prosthesis and tibial insert prosthese:
1) first according to the amputation bone model of femur, extract distal femur curved-surface shape, keep constant fairing and optimization, the acquisition femoral prosthesis curved-surface shape of carrying out of distal femur curved-surface shape; Then according to the reservation bone model of femur, extract osteotomy and retain surface of bone configuration of surface feature, design femoral prosthesis binding face feature; Finally add fixed structure, comprise and add stationary cylinder and rear end connection cylinder, obtain final femur replacement prosthesis cad model (as shown in Figure 8).
2), according to the reservation bone model of tibia, extract osteotomy and retain surface of bone configuration of surface feature, design tibial prosthesis binding face feature; Then hammer into thing with the design of tibial bone pulp cavity pattern, obtain final tibia replacement prosthesis cad model (as shown in Figure 9).
3) obtain the basic configuration of tibial insert prosthese according to femur replacement prosthesis curved surface mating surface, tibia amputation bone model, design tibial insert binding face feature, make itself and femoral prosthesis curved surface and tibial prosthesis structure optimum matching, obtain final tibial insert prosthese cad model (as shown in figure 10).
4, manufacture total knee replacement vacation according to the cad model of above-mentioned each prosthese and by 3D printing technique, it specifically comprises the following steps:
1) cad model of femur replacement prosthesis, tibia replacement prosthesis and tibial insert prosthese is imported in rapid shaping assistant software MaterialiseMagics and processed, comprise and put location, interpolation support and layering, and the hierarchical file obtaining is saved as to CLI form (as shown in figure 11).
2) hierarchical file is imported to the setting of carrying out scan mode selection and sweep span in RPPath software, obtain importing to rapid prototyping system Dimel-100 after two-dimension data, pass into noble gas, the 3D that carries out laser selective melting prints and manufactures.
Wherein, the 3D of laser selective melting prints to manufacture and is specially: flexible Pu Fen mechanism is entirely laid on powder on substrate, then laser scans according to the two-dimension data after model layering under computer control, after powder smelting, condense on lower one deck matrix, then moulding cylinder decline powder cylinder rises, the powder feeding again of Pu Fen mechanism, paving powder, melting powder, repeat this process, until manufactured.Above-mentioned flexible Pu Fen mechanism, moulding cylinder and powder cylinder all belong to the parts in rapid prototyping system Dimel-100, therefore repeat no more.
In a preferred embodiment, it is orthogonal scanning that 3D prints the scan mode of manufacturing, and sweep span is set to 0.08mm, processing bed thickness 0.035mm, scanning speed 700mm/s, laser power 160W.Need to illustrate, above-mentioned technological parameter is not fixing requirement, can change and correspondingly adjust according to rapid shaping processing environment.
In a preferred embodiment, noble gas is nitrogen or argon.
In a preferred embodiment, the manufactured materials of femur replacement prosthesis and tibia replacement prosthesis can be selected biomedical cochrome powder or titanium alloy powder, but is not limited only to this bi-material.
In a preferred embodiment, the manufactured materials of tibial insert prosthese can be selected biomedical High molecular weight polyethylene powder, but is not limited only to this kind of material.
3) take out femur replacement prosthesis, tibia replacement prosthesis and the tibial insert prosthese test specimen that 3D prints, implement the operations such as subsequent heat treatment, sandblast and polishing, complete the manufacture of full knee joint transposing prosthesis finished product.
The various embodiments described above are only for further describing object of the present invention, technical scheme and beneficial effect; be not limited to the present invention; within the spirit and principles in the present invention all; any modification of making, be equal to replacement, improvement etc., within protection scope of the present invention all should be included in.
Claims (10)
1. personalized reversal design and the manufacture method of full knee joint transposing prosthesis, is characterized in that, comprising:
1) set up the step of femur and tibia three-dimensional digitalization model based on the kneed medical image data of patient;
2) use virtual osteotomy software respectively femur and tibia three-dimensional digitalization model to be simulated the step of osteotomy;
3) step of the cad model of reversal design femur replacement prosthesis, tibia replacement prosthesis and tibial insert prosthese;
4) according to the cad model of above-mentioned each prosthese and manufacture the step of total knee replacement vacation by 3D printing technique.
2. personalized reversal design and the manufacture method of a kind of full knee joint transposing prosthesis as claimed in claim 1, is characterized in that, described step 1) specifically comprises:
1. the CT/MRI tomoscan image of the DICOM form based on patient's knee joint femur, use medical image software Mimics, the feature that shows different gray scales according to soft tissue from skeleton in image carries out that image is cut apart, after repairing treatment, carry out three-dimensionalreconstruction to obtain femur three-dimensional digitalization model, and be output as PLY formatted file;
2. the CT/MRI tomoscan image of the DICOM form based on patient's knee joint tibia, use medical image software Mimics, the feature that shows different gray scales according to soft tissue from skeleton in image carries out that image is cut apart, after repairing treatment, carry out three-dimensionalreconstruction to obtain tibia three-dimensional digitalization model, and be output as PLY formatted file.
3. personalized reversal design and the manufacture method of a kind of full knee joint transposing prosthesis as claimed in claim 1, is characterized in that, described step 2) specifically comprise:
1. the PLY formatted file of femur three-dimensional digitalization model is imported to Geomagic Studio software, the mechanical axis of model femur, then on the vertical of mechanical axis, find the surgery epicondyle line of femur, take femur mechanical axis as Z axis, surgery epicondyle line is X-axis, sets up three-dimensional system of coordinate according to right-handed Cartesian coordinate system rule; Complete behind the location of femur, simulate distal femur osteotomy according to the operation plan of total knee replacement, obtain the amputation bone model of femur and retain bone model, export as STL formatted file;
2. the PLY formatted file of tibia three-dimensional digitalization model is imported to Geomagic Studio software, the mechanical axis of model tibia, then take tibia mechanical axis as Z axis, surgery epicondyle line is X-axis, sets up three-dimensional system of coordinate according to right-handed Cartesian coordinate system rule; Complete behind the location of tibia, by 7 ° of tibia hypsokinesis, under Lateral tibial plateau, 10mm simulates proximal tibia osteotomy, obtains the amputation bone model of tibia and retains bone model, exports as STL formatted file.
4. personalized reversal design and the manufacture method of a kind of full knee joint transposing prosthesis as claimed in claim 1, is characterized in that, described step 3) specifically comprises:
1. first according to the amputation bone model of femur, extract distal femur curved-surface shape, keep constant fairing and optimization, the acquisition femoral prosthesis curved-surface shape of carrying out of distal femur curved-surface shape; Then according to the reservation bone model of femur, extract osteotomy and retain surface of bone configuration of surface feature, design femoral prosthesis binding face feature; Finally add fixed structure, comprise and add stationary cylinder and rear end connection cylinder, obtain final femur replacement prosthesis cad model;
2. according to the reservation bone model of tibia, extract osteotomy and retain surface of bone configuration of surface feature, design tibial prosthesis binding face feature; Then hammer into thing with the design of tibial bone pulp cavity pattern, obtain final tibia replacement prosthesis cad model;
3. obtain the basic configuration of tibial insert prosthese according to femur replacement prosthesis curved surface and tibia amputation bone model, the morphological characteristic of design tibial insert, make itself and femoral prosthesis curved surface and tibial prosthesis structure optimum matching, obtain final tibial insert prosthese cad model.
5. personalized reversal design and the manufacture method of a kind of full knee joint transposing prosthesis as claimed in claim 1, is characterized in that, described step 4) specifically comprises:
1. the cad model of femur replacement prosthesis, tibia replacement prosthesis and tibial insert prosthese is imported in rapid shaping assistant software MaterialiseMagics and processed, comprise and put location, interpolation support and layering, and the hierarchical file obtaining is saved as to CLI form;
2. hierarchical file is imported to the setting of carrying out scan mode selection and sweep span in RPPath software, obtain importing to rapid prototyping system after two-dimension data, pass into noble gas, the 3D that carries out laser selective melting prints and manufactures;
3. take out femur replacement prosthesis, tibia replacement prosthesis and tibial insert prosthese test specimen that 3D prints, implement the operation of subsequent heat treatment, sandblast and polishing, complete the manufacture of full knee joint transposing prosthesis finished product.
6. personalized reversal design and the manufacture method of a kind of full knee joint transposing prosthesis as claimed in claim 5, it is characterized in that, the step of described step 4) 2. in, the 3D of laser selective melting prints to manufacture and is specially: flexible Pu Fen mechanism is entirely laid on powder on substrate, then laser scans according to the two-dimension data after model layering under computer control, after powder smelting, condense on lower one deck matrix, then moulding cylinder decline powder cylinder rises, the powder feeding again of paving powder system, paving powder, melting powder, repeat this process, until manufactured.
7. personalized reversal design and the manufacture method of a kind of full knee joint transposing prosthesis as claimed in claim 6, is characterized in that, it is orthogonal scanning that 3D prints the scan mode of manufacturing, sweep span is set to 0.08mm, processing bed thickness 0.035mm, scanning speed 700mm/s, laser power 160W.
8. personalized reversal design and the manufacture method of a kind of full knee joint transposing prosthesis as described in claim 5 or 6 or 7, is characterized in that, noble gas is nitrogen or argon.
9. personalized reversal design and the manufacture method of a kind of full knee joint transposing prosthesis as described in claim 1 to 7 any one, it is characterized in that, the manufactured materials of femur replacement prosthesis and tibia replacement prosthesis is selected biomedical cochrome powder or titanium alloy powder.
10. personalized reversal design and the manufacture method of a kind of full knee joint transposing prosthesis as described in claim 1 to 7 any one, is characterized in that, the manufactured materials of tibial insert prosthese is selected biomedical High molecular weight polyethylene powder.
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