CN103859162A - Preparation method for high-purity tryptophan microelement chelate - Google Patents
Preparation method for high-purity tryptophan microelement chelate Download PDFInfo
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- CN103859162A CN103859162A CN201210541685.1A CN201210541685A CN103859162A CN 103859162 A CN103859162 A CN 103859162A CN 201210541685 A CN201210541685 A CN 201210541685A CN 103859162 A CN103859162 A CN 103859162A
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- tryptophan
- chelate
- amino acid
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- calcium
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Abstract
The invention provides a preparation method for a high-purity tryptophan microelement chelate. The method comprises the following steps: dissolving a certain amount of amino acid in water and reacting an aqueous amino acid solution with calcium oxide or calcium hydroxide at a room temperature so as to obtain a calcium amino acid chelate solution; and then reacting the calcium amino acid chelate solution with metal sulfate to obtain the target compound. The method in the invention prepares the high-purity tryptophan microelement chelate at low cost, and the prepared high-purity tryptophan microelement chelate has high stability, can be conveniently digested and absorbed by animals and is applicable as a feed additive.
Description
Technical field
The present invention relates to a kind of method of preparing high-purity Chelates of Amino Acids And Trace Elements, specifically refer to a kind of method of preparing tryptophan microelement chelate.
Background technology
Since oneth century, trace element uses and has experienced three developing stage as feed addictive: what use at first is micro-inorganic salts, is mainly sulfate and oxide etc., but in application, finds many defects.For example, with the antagonism of other nutriments, to the destruction of the nutrients such as vitamin, the low and mixture homogeneity of biological value is low etc.For overcoming these shortcomings, people bring into use trace mineral supplement second generation product-acylate.There is equally the weak points such as biology utilization rate is low, biochemical function is unstable in it.Trace element amino acid chelate is the new and effective feed addictive of a class that first 20 century 70s are succeeded in developing the earliest by U.S.'s ALBICN biology laboratory, have good stability, anti-interference, easily by animal absorb, biological value advantages of higher.Be described as the third generation product of micro-first additive.
China also studied and applies microelements aminophenol chelated since the eighties in 20th century, and had obtained good effect on pig, fowl, ruminant, rabbit and fish.Main product has methionine iron, copper methionine, cobalt methionine, lysine iron, Copper lysinate, tryptophan iron etc. at present, and some composite trace element amino-acid chelate additives.
Summary of the invention
The object of this invention is to provide a kind of preparation method of low-cost high-purity tryptophan microelement chelate.
The object of the invention is to reach by the following technical programs: first a certain amount of amino acid is dissolved in water, amino acid solution and calcium oxide or calcium hydroxide room temperature reaction, obtain amino acid calcium chelate solution, then reaction obtains target compound with metal sulfate.
The reaction equation of described preparation high-purity tryptophan microelement chelate is as follows:
Described trace element is the one in iron, copper, zinc, manganese.
Described soluble metal trace element is the one in ferrous sulfate, copper sulphate, zinc sulfate, manganese sulfate
The described reaction time is 0.5-3 hour.
Described reaction temperature is 20 ℃-80 ℃.
The specific embodiment
Embodiment 1
Tryptophan (15g, 0.2mol) is dissolved in 100ml water, adds CaO5.7g(0.1mol) (or 7.4g Ca (OH)
2).System is stirred, dissolve to CaO.After 30min, in system, add cupric sulfate pentahydrate (25.4g, 0.1mol).After a few minutes, system becomes thickness, reaction 30min.After reaction finishes, in system, add 80ml water, system is heated to 70-80 ℃, filters, and filter cake water cleans 2 times.Filtrate Vacuum Concentration is extremely dry.Obtain blue powder solid 21g.
Embodiment 2
Tryptophan (25g, 0.33mol) is dissolved in 120ml water, adds CaO (9.5g, 0.168).System is stirred, dissolve to CaO.After 30min, in system, add white vitriol (47.8g, 0.165).After reaction 30min, filter, filter cake washes with water 2 times.Filtrate is concentrated into dry, obtains white powder solid 35g.
Claims (3)
1. prepare the method for high-purity micro-tryptophan chelate for one kind, the step that it is characterized in that its preparation method is: first a certain amount of amino acid is dissolved in water, amino acid solution and calcium oxide or calcium hydroxide room temperature reaction, obtain amino acid calcium chelate solution, then reaction obtains target compound with metal sulfate.
2. the method for preparing as claimed in claim 1 tryptophan microelement chelate, is characterized in that: described trace element is the one in iron, copper, zinc, manganese.
3. the method for preparing as claimed in claim 1 tryptophan microelement chelate, is characterized in that: soluble metal trace element is the one in ferrous sulfate, copper sulphate, zinc sulfate, manganese sulfate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210541685.1A CN103859162A (en) | 2012-12-14 | 2012-12-14 | Preparation method for high-purity tryptophan microelement chelate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210541685.1A CN103859162A (en) | 2012-12-14 | 2012-12-14 | Preparation method for high-purity tryptophan microelement chelate |
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| CN103859162A true CN103859162A (en) | 2014-06-18 |
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| CN201210541685.1A Pending CN103859162A (en) | 2012-12-14 | 2012-12-14 | Preparation method for high-purity tryptophan microelement chelate |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110663823A (en) * | 2019-11-05 | 2020-01-10 | 化学工业（全国）饲料添加剂工程技术中心山东科技公司 | Preparation method of feed additive copper methionine |
| CN115594545A (en) * | 2022-11-15 | 2023-01-13 | 石家庄上争信息科技有限公司（Cn） | Method for producing Gly-containing water-soluble fertilizer |
-
2012
- 2012-12-14 CN CN201210541685.1A patent/CN103859162A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110663823A (en) * | 2019-11-05 | 2020-01-10 | 化学工业（全国）饲料添加剂工程技术中心山东科技公司 | Preparation method of feed additive copper methionine |
| CN115594545A (en) * | 2022-11-15 | 2023-01-13 | 石家庄上争信息科技有限公司（Cn） | Method for producing Gly-containing water-soluble fertilizer |
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Legal Events
| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140618 |