CN103082088A - Preparation method of glycine trace element chelate with high purity - Google Patents
Preparation method of glycine trace element chelate with high purity Download PDFInfo
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- CN103082088A CN103082088A CN 201110342037 CN201110342037A CN103082088A CN 103082088 A CN103082088 A CN 103082088A CN 201110342037 CN201110342037 CN 201110342037 CN 201110342037 A CN201110342037 A CN 201110342037A CN 103082088 A CN103082088 A CN 103082088A
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- chelate
- glycine
- amino acid
- trace element
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Abstract
The invention provides a preparation method of a glycine trace element chelate with high purity. The method comprises the following steps: first, dissolving a certain amount of amino acid in water; reacting the amino acid aqueous solution and calcium oxide or calcium hydroxide at room temperature to obtain a calcium amino acid chelate solution; and then reacting the calcium amino acid chelate solution with metal sulfate to obtain a target compound. The method provided by the invention prepares the glycine trace element chelate with high purity at a low cost; and the chelate has high stability, is conducive to digestion and absorption of animal body, and can be used as a feed additive.
Description
Technical field
The present invention relates to a kind of method for preparing high-purity Chelates of Amino Acids And Trace Elements, specifically refer to a kind of method for preparing the glycine microelement chelate.
Background technology
Since oneth century, trace element uses as feed addictive and experienced three developing stage: what use at first is the inorganic salts of trace element, is mainly sulfate and oxide etc., but finds many defectives in application.For example with the antagonism of other nutriments, to the destruction of the nutrients such as vitamin, the low and mixture homogeneity of biological value is low etc.For overcoming these shortcomings, people bring into use trace mineral supplement second generation product-acylate.There are the weak points such as the biology utilization rate is low, biochemical function is unstable equally in it.Trace element amino acid chelate is the new and effective feed addictive of class that at first 20 century 70s are succeeded in developing the earliest by U.S.'s ALBICN biology laboratory, have good stability, anti-interference, easily by animal absorb, the biological value advantages of higher.Be described as the third generation product of micro-first additive.
China also studied and uses microelements aminophenol chelated since the eighties in 20th century, and had obtained effect preferably on pig, fowl, ruminant, rabbit and fish.Main product has methionine iron, copper methionine, cobalt methionine, lysine iron, Copper lysinate, ferrous glycine etc. at present, and some composite trace element amino-acid chelate additives.
At present, all exist product purity low existing the preparation in the method for methionine microelement chelate, the phenomenon that stability is looked into is unfavorable for digesting and assimilating of animal.In addition, in prior art, the amount of methionine has all substantially exceeded micro-amount, has increased cost.
Summary of the invention
The preparation method who the purpose of this invention is to provide a kind of low-cost high-purity glycine microelement chelate.
The objective of the invention is to reach by the following technical programs: at first a certain amount of amino acid is dissolved in water, amino acid solution and calcium oxide or calcium hydroxide room temperature reaction, obtain the amino acid calcium chelate solution, then reaction obtains target compound with metal sulfate.
The reaction equation of described preparation high-purity glycine microelement chelate is as follows:
Described trace element is a kind of in iron, copper, zinc, manganese.
Described soluble metal trace element is a kind of in ferrous sulfate, copper sulphate, zinc sulfate, manganese sulfate
The described reaction time is 0.5-3 hour.
Described reaction temperature is 20 ℃-80 ℃.
The specific embodiment
Embodiment 1
Glycine (15g, 0.2mol) is dissolved in 100ml water, adds CaO5.7g(0.1mol) (perhaps 7.4g Ca (OH)
2).System is stirred, dissolve to CaO.After 30min, add cupric sulfate pentahydrate (25.4g, 0.1mol) in system.The system thickness that becomes after a few minutes, reaction 30min.Reaction adds 80ml water after finishing in system, system is heated to 70-80 ℃, filters, and the filter cake water cleans 2 times.The filtrate Vacuum Concentration is extremely done.Obtain blue powder solid 21g.
Embodiment 2
Glycine (25g, 0.33mol) is dissolved in 120ml water, adds CaO (9.5g, 0.168).System is stirred, dissolve to CaO.After 30min, add white vitriol (47.8g, 0.165) in system.After reaction 30min, filter, filter cake washes with water 2 times.Filtrate is concentrated into dried, obtains white powder solid 35g.
Embodiment 3
Glycine (15g, 0.2mol) is dissolved in 100ml water, adds CaO (5.7g, 0.1mol) that system is stirred, dissolve to CaO.After 30min, add a water water manganese sulfate (16.9g, 0.1mol) in system.Reaction 30min.After reaction finishes, filter, the filter cake water cleans 2 times.The filtrate Vacuum Concentration is extremely done.Obtain light brown powder solid 20g.
Claims (6)
1. method for preparing high-purity micro-glycine chelate thing, the step that it is characterized in that its preparation method is: at first a certain amount of amino acid is dissolved in water, amino acid solution and calcium oxide or calcium hydroxide room temperature reaction, obtain the amino acid calcium chelate solution, then reaction obtains target compound with metal sulfate.
2. prepare as claimed in claim 1 the method for glycine microelement chelate, it is characterized in that: described preparation glycine microelement chelate reaction equation is as follows:
3. prepare as claimed in claim 1 the method for glycine microelement chelate, it is characterized in that: described trace element is a kind of in iron, copper, zinc, manganese.
4. prepare as claimed in claim 1 the method for glycine microelement chelate, it is characterized in that: a kind of in ferrous sulfate, copper sulphate, zinc sulfate, manganese sulfate of soluble metal trace element.
5. prepare as claimed in claim 1 the method for glycine microelement chelate, it is characterized in that: the described reaction time is 0.5-3 hour.
6. prepare as claimed in claim 1 the method for methionine microelement chelate, it is characterized in that: described reaction temperature is 20 ℃-80 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN 201110342037 CN103082088A (en) | 2011-11-03 | 2011-11-03 | Preparation method of glycine trace element chelate with high purity |
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| CN 201110342037 CN103082088A (en) | 2011-11-03 | 2011-11-03 | Preparation method of glycine trace element chelate with high purity |
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| CN103082088A true CN103082088A (en) | 2013-05-08 |
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| CN 201110342037 Pending CN103082088A (en) | 2011-11-03 | 2011-11-03 | Preparation method of glycine trace element chelate with high purity |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109043221A (en) * | 2018-09-25 | 2018-12-21 | 建德市维丰饲料有限公司 | A kind of preparation method of feed pre-mixing material for poultry and products thereof and application |
| CN110663823A (en) * | 2019-11-05 | 2020-01-10 | 化学工业（全国）饲料添加剂工程技术中心山东科技公司 | Preparation method of feed additive copper methionine |
| JP2020526563A (en) * | 2017-07-14 | 2020-08-31 | シージェイ チェイルジェダン コーポレーション | Methionine-metal chelate and its manufacturing method |
| CN114163342A (en) * | 2021-12-28 | 2022-03-11 | 山东亚太海华生物科技有限公司 | Preparation method of manganese glycinate for feed with high manganese content |
| CN115594545A (en) * | 2022-11-15 | 2023-01-13 | 石家庄上争信息科技有限公司（Cn） | Method for producing Gly-containing water-soluble fertilizer |
-
2011
- 2011-11-03 CN CN 201110342037 patent/CN103082088A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020526563A (en) * | 2017-07-14 | 2020-08-31 | シージェイ チェイルジェダン コーポレーション | Methionine-metal chelate and its manufacturing method |
| CN109043221A (en) * | 2018-09-25 | 2018-12-21 | 建德市维丰饲料有限公司 | A kind of preparation method of feed pre-mixing material for poultry and products thereof and application |
| CN110663823A (en) * | 2019-11-05 | 2020-01-10 | 化学工业（全国）饲料添加剂工程技术中心山东科技公司 | Preparation method of feed additive copper methionine |
| CN114163342A (en) * | 2021-12-28 | 2022-03-11 | 山东亚太海华生物科技有限公司 | Preparation method of manganese glycinate for feed with high manganese content |
| CN114163342B (en) * | 2021-12-28 | 2023-11-24 | 山东亚太海华生物科技有限公司 | Preparation method of manganese glycinate for feed with high manganese content |
| CN115594545A (en) * | 2022-11-15 | 2023-01-13 | 石家庄上争信息科技有限公司（Cn） | Method for producing Gly-containing water-soluble fertilizer |
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Application publication date: 20130508 |