CN103845667A - Traditional Chinese medicine for treating drug-resistant tuberculosis - Google Patents
Traditional Chinese medicine for treating drug-resistant tuberculosis Download PDFInfo
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- CN103845667A CN103845667A CN201210529041.0A CN201210529041A CN103845667A CN 103845667 A CN103845667 A CN 103845667A CN 201210529041 A CN201210529041 A CN 201210529041A CN 103845667 A CN103845667 A CN 103845667A
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Abstract
The invention discloses traditional Chinese medicine for treating drug-resistant tuberculosis, which belongs to the technical field of medicine. The traditional Chinese medicine is prepared according to the following formula: 2-5g of radix stemonae, 1-3g of ternate buttercup root, 0.5-2g of begonia grass and 3-6g of boschniakia rossica. The traditional Chinese medicine disclosed by the invention is prepared on the basis of understanding and treatment principle of tuberculosis pathogenesis with reference to modern pharmacological research, has a very satisfactory curative effect on bone tuberculosis, intestinal tuberculosis, pelvic tuberculosis and tuberculosis of cervical lymph nodes and the like while treating tuberculosis, and is short in course of treatment, good in curative effect and free of side effects.
Description
Technical field
The present invention relates to medical technical field, specifically, relate to a kind of Chinese medicine for the treatment of drug-resistant tuberculosis.
Background technology
Tuberculosis is a kind of chronic infectious disease of serious harm people ' s health, and at present the whole world 2,000,000,000 people that have an appointment are infected, newly occur every year the about 800-1000 ten thousand of tuberculosis patient, every year because tuberculosis death toll is about 200-300 ten thousand.At present, China's tuberculosis year number of the infected is about 1,300,000, because tuberculosis death toll reaches 130,000 every year, exceedes the summation of other Death of Infectious Diseases number.China is one of 22 popular serious countries of tuberculosis in the whole world, is also one of 27 popular serious countries of drug-resistant tuberculosis in the whole world simultaneously.China's tuberculosis number of patients occupies second place of the world, is only second to India.Thereby tuberculosis is one of major disease of China's priority control.
Tuberculosis is the chronic infectious disease being caused by mycobacterium tuberculosis complex (Mycobacterium tuberculosis complex is called for short mycobacterium tuberculosis or tulase), can involve the many tracts of whole body.Modal disease sites is lungs, accounts for the 80-90% of each organ tuberculosis sum, also can involve the organs such as liver, kidney, brain, lymph node.There are respiratory tract, digestive tract, skin and uterus in main route of transmission lungy, but is mainly to pass through respiratory tract.After the pulmonary tuberculosis patient sputum of discharge of bacteria is dry, antibacterial is with stirring up a cloud of dust, and sucked and whether cause that infection, human body suck the spittle that contains mycobacterium tuberculosis ill mainly relevant by many factors such as the resistances of the quantity of suction tulase, virulence, human body by other people.
Classification lungy is as follows:
1, primary pulmonary tuberculosis.Mycobacterium tuberculosis is entered in lung by respiratory tract, and produce primary effusion focus at this, focus multidigit is under the visceral pleura on the top of upper infralobar part or inferior lobe, the lymphatic vessel of local drainage is invaded and is caused tuberculous lymphangitis, mycobacterium tuberculosis can be drained to hilar lymph node with lymphatic vessel, causes tuberculous lymphadenitis.The major lesions of primary pulmonary tuberculosis is primary lesion in lung, and lymphangitis and pulomonary hilar lymphoid tuberculosis, also claim primary complex.
2, hematogenous pulmonary tuberculosis.Mycobacterium tuberculosis in lung in primary lesion is invaded blood flow can cause disseminated tuberculosis disease, and acute hematogenous disseminated tuberculosis disease claims again phthisis miliaris, and rabat CT shows as two lung diffusivity foxtail millet burl joint shadows, and tuberosity size is more consistent, distribution uniform.When repeatedly entering blood flow, a small amount of tulase can cause subacute hematogenous pulmonary tuberculosis pulmonary tuberculosis.
3, secondary pulmonary tuberculosis.After primary pulmonary tuberculosis spontaneous recovery or healing, body infects the tuberculosis that mycobacterium tuberculosis causes again.Be more common in adult.The pathogenesis of secondary pulmonary tuberculosis has two kinds of viewpoints, Endogenous relapse and Exogenous reinfections.Endogenous relapse refer to the mycobacterium tuberculosis of hiding in body under suitable condition again breeding cause activeness pathological changes, Exogenous reinfection to refer to that primary tuberculosis fully recovers, again invade body by extraneous mycobacterium tuberculosis and the tuberculosis that again causes.
4, tuberculous pleuritis.Comprise tuberculous dry pleurisy, tuberculous exadative pleurisy, tuberculous empyema.
5, the outer tuberculosis of other lungs.The outer tuberculosis of other lungs is named by position and internal organs, as: tuberculosis of bone and joint, tuberculous meningitis, renal tuberculosis, tuberculosis of intestine etc.
Clinical manifestation lungy: phthisical clinical manifestation variation, can there is no in early days symptom, part patient symptom is slight, easily think by mistake be flu and ignore.Typical pulmonary tuberculosis onset is slow, and the course of disease is longer, can have low grade fever, asthenia, inappetence, cough and spitting of blood.But Most lesions is slight, can be asymptomatic, even being found in the time of health check-up.Small part patient has outstanding poisoning symptom, is more common in miliary tuberculosis or caseous pneumonia.Senile pulmonary tuberculosis patient's symptom is easily covered by chronic bronchitis shape all the year round.
At present, clinically in treatment lungy, doctor trained in Western medicine adopts cleans operation and medicine chemotherapeutic treatment, and with the immune function of enhancing body, still, western medical treatment can produce certain side effect to human body, and therapeutic effect is not fine.And existing treatment Chinese medicine lungy has, curative effect is long, therapeutic effect is not obvious and easily cause the defects such as drug resistance.At present, not yet find effectively, can treat in a short time Chinese medicine lungy.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine for the treatment of drug-resistant tuberculosis, solve above technical problem.
For addressing the above problem, the technical solution adopted in the present invention is:
A Chinese medicine for the treatment of drug-resistant tuberculosis, is characterized in that: described Chinese medicine is formed by following formulated: hundred 2-5 gram of milk root, Radix Ranunculi Ternati 1-3 gram, Radix Semiaquilegiae 0.5-2 gram, Herba Cynomorii 3-6 gram.
Say further, described Chinese medicine is formed by following formulated: hundred 3 grams of milk roots, 2 grams of Radix Ranunculi Ternatis, 1 gram of Radix Semiaquilegiae, 5 grams of Herba Cynomorii.
The property of medicine, the pharmacology of the Chinese medicine using in the formula of medicine of the present invention are as follows:
Hundred milk roots, are called again the Radix Stemonae, sweet in the mouth, hardship; Slightly warm in nature; Return lung meridian.The effect of there is the cough-relieving of lung moistening the chest stuffiness relieving, killing consumptive disease worm.Can be used for treating new chronic cough and cough, pulmonary tuberculosis cough, spitting of blood chest pain, passes corpse stream chronic infectious disease.It is warm in nature and not hot, and cold and heat are coughed and be shoulded it, and this is different ear.
Radix Ranunculi Ternati, sweet in the mouth, pungent; Slightly warm in nature; Return liver, lung meridian.There is the effect such as dissipating phlegm and resolving masses, removing toxic substances and promoting subsidence of swelling; Cure mainly: scrofula sucutaneous nodule, furuncle, worm venom, migraine, malaria, toothache, pulmonary tuberculosis, tuberculous lymphadenitis, lymphadenitis, pharyngolaryngitis.Radix Ranunculi Ternati is the tuber of cohosh ranunculus ternatus, because of its tuber meat, and several clustering, nearly spindle, crust yellowish-brown, likeness in form ram's horn and gaining the name.Modern pharmacology and clinical research show Radix Ranunculi Ternati and preparation effective in cure to pulmonary tuberculosis, lymphoid tuberculosis and kinds cancer and lymphoma.
Radix Semiaquilegiae, claims again mouse dung grass.Bitter in the mouth, cold nature.There is the effect such as removing toxic substances and promoting subsidence of swelling, relieving stranguria by diuresis.Cure mainly the diseases such as scrofula carbuncle, snake bite and insect sting, hernia, urine leaching pain.
Herba Cynomorii, formal name used at school Herba Boschniakiae Rossicae, popular name Herba Orobanches.Sweet in the mouth, salty; Warm in nature; Can all herbal medicine, there is the function of kidney invigorating and YANG supporting, loosening bowel to relieve constipation and hemostasis.If cooperation other drug, can treat the reproductive system diseases such as sexual impotence, chills and pain of the waist and kness, nocturnal emission and woman's acyesis, also can be used for treating the various diseases such as senility habitual constipation, cystitis, hematuria.In addition, it excites heart vigor in addition, promotes the function of body immunity and allaying tiredness.On the root of the Alnus plant of Herba Cynomorii multiparasitization on the steep ditch formula overhanging cliff of height above sea level 1450-1800 rice, it is the rare medicinal plants in Changbai Mountain.Herba Cynomorii is famous and precious in all over the world with its distinctive pharmacological action, and folklore has the special effects such as kidney invigorating and YANG supporting, loosening bowel to relieve constipation, body-building, life lengthening.Chinese Academy of Sciences's school of life and health sciences finds through the research of 11 years, and in Herba Cynomorii, contain the super kinases of a large amount of CR, the super kinases of CR is a kind of material that changes cell metabolism, has the effect of repairing tender constitution gene and cell activity enhancing.
Beneficial effect: the present invention is understanding and the Therapeutic Principle based on to Tuberculosis mechanism, formulated with reference to modern pharmacological research, in the phthisical while for the treatment of, bone tuberculosis, tuberculosis of intestine, pelvic cavity Fructus Citri tangerinae core and the tuberculosis of cervical lymph nodes etc. are had to good curative effect, short treating period, good effect, have no side effect.
The specific embodiment
Below in conjunction with specific embodiment, the present invention will be further described.
Embodiment 1:
Described in the present embodiment, treat the Chinese medicine of drug-resistant tuberculosis, formed by following formulated: hundred 2 grams of milk roots, 1 gram of Radix Ranunculi Ternati, 0.5 gram of Radix Semiaquilegiae, 3 grams of Herba Cynomorii.
Embodiment 2:
Described in the present embodiment, treat the Chinese medicine of drug-resistant tuberculosis, formed by following formulated: hundred 5 grams of milk roots, 3 grams of Radix Ranunculi Ternatis, 2 grams of Radix Semiaquilegiae, 6 grams of Herba Cynomorii.
Embodiment 3:
Described in the present embodiment, treat the Chinese medicine of drug-resistant tuberculosis, formed by following formulated: hundred 3 grams of milk roots, 2 grams of Radix Ranunculi Ternatis, 1 gram of Radix Semiaquilegiae, 5 grams of Herba Cynomorii.
Case-data
100 routine MethodsThe cases enrolled, are the hospital outpatient patient of Pan county Seedling man between in May, 1999-2012 year JIUYUE, are diagnosed as Pulmonary Tuberculosis Infection patient, wherein male 57 examples, female's 43 examples; Disease time is 3 months to 3 years.
Diagnostic criteria: tcm diagnosis standard is with reference to the high medical teaching material Chinese Internal Medicine standard of national Chinese medicine, Western medicine diagnose standard is with reference to x-ray, breast CT, PPD, report is made a definite diagnosis in the checks such as national Disease Control and Prevention Center expectorant inspection.
38 male's examples recurred for once taking after tetrad medicine (ethamine is stung alcohol for rifampicin, isoniazid, the first amine of the pyrrole Qin) is cured; 11 routine male patients are at hospitalization, because hydrothorax requires to take the Chinese medicine of the present invention treatment of helping each other repeatedly simultaneously; 8 examples are serious because of gastrointestinal reaction for taking after tetrad medicine, occur gastralgic vomitting, have loose bowels, fixed drug eruption and abandon tetrad chemotherapy, require Chinese traditional treatment.It is 3 months to 19 monthly obtaining entirely more that male organizes average medicine time, and criterion of cure is that General Symptoms disappears, and expectorant is examined continuous 3 months 3 times and checked feminine gender, the two lung no abnormality seens of breast CT inspection, and patient recovers normal work.
Women's group mean age was at 20 to 75 years old.Wherein, the youngster of 17 examples for going out to work, once hospitalization, the medical history of taking medicine, does not cure or recurrence completely, on average takes after Chinese medicine 3-7 of the present invention month, fully recovers and returns to place of working.16 examples are cavernous pulmonary tuberculosis patient, and average sick time is 3-9, all have the history of kimonos tetrad medicine treatment in hospital, on average take after Chinese medicine 6-19 of the present invention month, and General Symptoms disappears, and breast CT checks empty calcification, recovers orthobiosis.10 examples, for joining the army or the asymptomatic recessive pulmonary tuberculosis of college entrance examination health check-up discovery, are on average taken after Chinese medicine 2-3 of the present invention month, and it is abnormal that CT check has no two lungs, expectorant inspection feminine gender.
Claims (2)
1. a Chinese medicine for the treatment of drug-resistant tuberculosis, is characterized in that: described Chinese medicine is formed by following formulated: hundred 2-5 gram of milk root, Radix Ranunculi Ternati 1-3 gram, Radix Semiaquilegiae 0.5-2 gram, Herba Cynomorii 3-6 gram.
2. the Chinese medicine for the treatment of according to claim 1 drug-resistant tuberculosis, is characterized in that: described Chinese medicine is formed by following formulated: hundred 3 grams of milk roots, 2 grams of Radix Ranunculi Ternatis, 1 gram of Radix Semiaquilegiae, 5 grams of Herba Cynomorii.
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Citations (3)
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| CN1911411A (en) * | 2006-08-21 | 2007-02-14 | 赵静平 | Traditional Chinese medicine prepn. for treating nephrotuberculosis |
| CN101028470A (en) * | 2006-03-03 | 2007-09-05 | 夏俊飞 | Medicinal composition for treating phthisis |
| CN101982193A (en) * | 2010-11-09 | 2011-03-02 | 吉林一正药业集团有限公司 | Traditional Chinese medicine composition for treating pulmonary tuberculosis, preparation method and application thereof |
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Patent Citations (3)
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|---|---|---|---|---|
| CN101028470A (en) * | 2006-03-03 | 2007-09-05 | 夏俊飞 | Medicinal composition for treating phthisis |
| CN1911411A (en) * | 2006-08-21 | 2007-02-14 | 赵静平 | Traditional Chinese medicine prepn. for treating nephrotuberculosis |
| CN101982193A (en) * | 2010-11-09 | 2011-03-02 | 吉林一正药业集团有限公司 | Traditional Chinese medicine composition for treating pulmonary tuberculosis, preparation method and application thereof |
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| 《中国家庭医生大全》编辑部编著: "《中国家庭医生大全》", 31 July 2008, 陕西师范大学出版社 * |
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