CN103842793B - 样品施给器感测和放置 - Google Patents

样品施给器感测和放置 Download PDF

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Publication number
CN103842793B
CN103842793B CN201280046044.7A CN201280046044A CN103842793B CN 103842793 B CN103842793 B CN 103842793B CN 201280046044 A CN201280046044 A CN 201280046044A CN 103842793 B CN103842793 B CN 103842793B
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CN
China
Prior art keywords
sample applicator
substrate
sample
applicator
image
Prior art date
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CN201280046044.7A
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English (en)
Chinese (zh)
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CN103842793A (zh
Inventor
R.扎尼瑟
D.扎尼瑟
S.康罗伊
E.莱克内斯
M.扎尼瑟
F.波洛斯基
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Constitution Medical Inc
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Constitution Medical Inc
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Publication of CN103842793A publication Critical patent/CN103842793A/zh
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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B11/00Measuring arrangements characterised by the use of optical techniques
    • G01B11/14Measuring arrangements characterised by the use of optical techniques for measuring distance or clearance between spaced objects or spaced apertures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31Apparatus therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1011Control of the position or alignment of the transfer device
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/11Region-based segmentation
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/12Edge-based segmentation
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/50Depth or shape recovery
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/70Determining position or orientation of objects or cameras
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00Scenes; Scene-specific elements
    • G06V20/60Type of objects
    • G06V20/69Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/695Preprocessing, e.g. image segmentation
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Multimedia (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Length Measuring Devices By Optical Means (AREA)
  • Coating Apparatus (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201280046044.7A 2011-07-22 2012-07-13 样品施给器感测和放置 Active CN103842793B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161510728P 2011-07-22 2011-07-22
US61/510,728 2011-07-22
PCT/US2012/046784 WO2013016037A1 (en) 2011-07-22 2012-07-13 Sample applicator sensing and positioning

Publications (2)

Publication Number Publication Date
CN103842793A CN103842793A (zh) 2014-06-04
CN103842793B true CN103842793B (zh) 2016-05-25

Family

ID=46651589

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280046044.7A Active CN103842793B (zh) 2011-07-22 2012-07-13 样品施给器感测和放置

Country Status (8)

Country Link
US (2) US9146247B2 (enExample)
EP (1) EP2734825B1 (enExample)
JP (1) JP6106170B2 (enExample)
CN (1) CN103842793B (enExample)
AU (1) AU2012287302B2 (enExample)
CA (1) CA2842685A1 (enExample)
ES (1) ES2774942T3 (enExample)
WO (1) WO2013016037A1 (enExample)

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US9039992B2 (en) 2011-06-06 2015-05-26 Abbott Laboratories Apparatus for closed tube sampling and open tube sampling for automated clinical analyzers
ES2719846T3 (es) * 2011-07-22 2019-07-16 Roche Diagnostics Hematology Inc Sistemas y métodos de preparación de muestras de fluidos
US9121705B2 (en) * 2012-04-20 2015-09-01 Massachusetts Institute Of Technology Sensor for simultaneous measurement of thickness and lateral position of a transparent object
AU2013289898A1 (en) * 2012-07-13 2015-01-22 Roche Diagnostics Hematology, Inc. Controlled dispensing of samples onto substrates
JP6290651B2 (ja) * 2014-02-27 2018-03-07 株式会社キーエンス 画像測定器
JP6278741B2 (ja) * 2014-02-27 2018-02-14 株式会社キーエンス 画像測定器
CN105934663B (zh) 2014-03-20 2020-01-14 深圳迈瑞生物医疗电子股份有限公司 推片染色机及其推片控制方法、装置
EP3124912B1 (en) * 2015-07-30 2019-01-16 Unity Semiconductor GmbH Method and assembly for determining the thickness of a layer in a stack of layers
US10782306B2 (en) * 2015-12-24 2020-09-22 Koninklijke Philips N.V. Method and a system for determinations of cell suspensions
US10648905B2 (en) 2016-08-31 2020-05-12 Abbott Laboratories Systems, apparatus, and related methods for evaluating biological sample integrity
WO2019035077A1 (en) 2017-08-17 2019-02-21 Abbott Point Of Care Inc. DEVICES, SYSTEMS AND METHODS FOR PERFORMING OPTICAL ASSAYS
US11067526B2 (en) 2017-08-17 2021-07-20 Abbott Point Of Care Inc. Devices, systems, and methods for performing optical and electrochemical assays
EP3620771A1 (de) * 2018-09-06 2020-03-11 Siemens Healthcare Diagnostics Inc. Vorrichtung zum ausbringen von blut auf einem substrat
CN111239164B (zh) * 2020-04-02 2023-04-07 上海御微半导体技术有限公司 一种缺陷检测装置及其方法
KR20210145010A (ko) * 2020-05-22 2021-12-01 삼성전자주식회사 웨이퍼 검사 장치
WO2022074595A1 (en) * 2020-10-07 2022-04-14 Xtpl S. A. Methods of extruding a nanoparticle composition onto a substrate
CN113050667B (zh) * 2021-02-05 2022-02-08 广东国地规划科技股份有限公司 一种无人机采样控制方法、控制器及其系统
WO2025119902A1 (en) 2023-12-04 2025-06-12 F. Hoffmann-La Roche Ag Hemoglobin determination methods and systems

Citations (9)

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US5416609A (en) * 1992-05-13 1995-05-16 Minolta Co., Ltd. Image pickup apparatus for focusing an object image based on mirror reflected height of the object
US5437242A (en) * 1992-09-17 1995-08-01 Wacker-Chemitronic Gessellschaft Fuer Elektronik-Grundstoffe Mbh Process and apparatus for controlling the melt level while pulling single crystals
US5953125A (en) * 1995-09-01 1999-09-14 Zygo Corporation Optical gap measuring apparatus and method
CN1508594A (zh) * 2002-12-18 2004-06-30 Lg.菲利浦Lcd株式会社 液晶显示面板的分配器及控制基板与喷嘴之间间隙的方法
US20050151092A1 (en) * 2003-10-14 2005-07-14 Olympus Corporation Manipulator apparatus, manipulating system, image processing apparatus, program, and apparatus controlling process
CN1685238A (zh) * 2002-09-27 2005-10-19 株式会社岛津制作所 用于液体分注的方法及装置
CN100350556C (zh) * 2004-03-23 2007-11-21 大日本网目版制造株式会社 处理装置
US20080210894A1 (en) * 2004-05-12 2008-09-04 Top Engineering Co., Ltd. Sealant dispenser and control method thereof
US20090269799A1 (en) * 2008-04-25 2009-10-29 Constitutional Medical Investors, Inc. Method of determining a complete blood count and a white blood cell differential count

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US4618261A (en) * 1984-01-16 1986-10-21 Massachusetts Institute Of Technology Optical gap measuring
FR2782800B1 (fr) 1998-09-01 2000-10-20 Abx Sa Dispositif pour la preparation automatique d'etalements sanguins sur des lames
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US7295026B2 (en) * 2005-06-03 2007-11-13 Ut-Battelle, Llc Automated position control of a surface array relative to a liquid microjunction surface sampler
ATE468076T1 (de) * 2006-11-22 2010-06-15 Health Robotics Srl Verfahren und maschine zur handhabung giftiger stoffe
US8248590B2 (en) 2008-01-28 2012-08-21 Siemens Healthcare Diagnostics Inc. Method and apparatus for auxiliary illumination for detecting an object
WO2010055558A1 (ja) * 2008-11-12 2010-05-20 富士通株式会社 文字領域抽出装置,文字領域抽出機能を備えた撮像装置,および文字領域抽出プログラム
JP2011080952A (ja) * 2009-10-09 2011-04-21 Osaka Univ 距離測定装置、距離測定方法、距離測定プログラム、およびコンピュータ読み取り可能な記録媒体
US20120024416A1 (en) 2010-07-29 2012-02-02 Helena Laboratories Corporation System and method for dispensing fluid from a container and into a fluid receptacle
JP5801410B2 (ja) 2010-11-10 2015-10-28 コンスティテューション・メディカル・インコーポレイテッドConstitution Medical, Inc. 検査用に生物試料を準備するための自動化されたシステムおよび方法

Patent Citations (9)

* Cited by examiner, † Cited by third party
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US5416609A (en) * 1992-05-13 1995-05-16 Minolta Co., Ltd. Image pickup apparatus for focusing an object image based on mirror reflected height of the object
US5437242A (en) * 1992-09-17 1995-08-01 Wacker-Chemitronic Gessellschaft Fuer Elektronik-Grundstoffe Mbh Process and apparatus for controlling the melt level while pulling single crystals
US5953125A (en) * 1995-09-01 1999-09-14 Zygo Corporation Optical gap measuring apparatus and method
CN1685238A (zh) * 2002-09-27 2005-10-19 株式会社岛津制作所 用于液体分注的方法及装置
CN1508594A (zh) * 2002-12-18 2004-06-30 Lg.菲利浦Lcd株式会社 液晶显示面板的分配器及控制基板与喷嘴之间间隙的方法
US20050151092A1 (en) * 2003-10-14 2005-07-14 Olympus Corporation Manipulator apparatus, manipulating system, image processing apparatus, program, and apparatus controlling process
CN100350556C (zh) * 2004-03-23 2007-11-21 大日本网目版制造株式会社 处理装置
US20080210894A1 (en) * 2004-05-12 2008-09-04 Top Engineering Co., Ltd. Sealant dispenser and control method thereof
US20090269799A1 (en) * 2008-04-25 2009-10-29 Constitutional Medical Investors, Inc. Method of determining a complete blood count and a white blood cell differential count

Also Published As

Publication number Publication date
JP6106170B2 (ja) 2017-03-29
JP2014521938A (ja) 2014-08-28
US9146247B2 (en) 2015-09-29
ES2774942T3 (es) 2020-07-23
AU2012287302A1 (en) 2013-05-02
HK1193469A1 (zh) 2014-09-19
AU2012287302B2 (en) 2015-02-19
CA2842685A1 (en) 2013-01-31
CN103842793A (zh) 2014-06-04
EP2734825A1 (en) 2014-05-28
US20160011223A1 (en) 2016-01-14
EP2734825B1 (en) 2020-01-01
WO2013016037A1 (en) 2013-01-31
US20130021461A1 (en) 2013-01-24

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