CN1038303C - Process for preparing high efficient oral haemorrhoids drug - Google Patents
Process for preparing high efficient oral haemorrhoids drug Download PDFInfo
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- CN1038303C CN1038303C CN91111946A CN91111946A CN1038303C CN 1038303 C CN1038303 C CN 1038303C CN 91111946 A CN91111946 A CN 91111946A CN 91111946 A CN91111946 A CN 91111946A CN 1038303 C CN1038303 C CN 1038303C
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- vitamin
- haemorrhoids
- drug
- hemorrhoid
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Abstract
The present invention relates to a method for making an oral tablet for treating piles. The method comprises the following steps: in the existence pf auxiliary materials such as starch, tartaric acid and dextrin, vitamin C, acetic acid, vitamin E and vitamin P are made into tablets by mixing, solution preparation, granulation, drying and granule rectification; each tablet weighs 0.3g. Patients take the tablets for three times per day and 2 tablets each time; patients with light piles can be healed in one week, and patients with serious piles can be healed in four weeks.
Description
The present invention relates to a kind of manufacture method of hemorrhoid medicine.
In state-owned sentence proverb, " ten people, nine hemorrhoid " visible hemorrhoid harm is big.The method of treatment hemorrhoid can be divided into 3 kinds at present.The 1st kind is external suppository, and on the market as ZHICHUAN SHUAN such as xiaozhiling injection and hibitane, this class exterior-applied article can only relief of symptoms, can not effect a radical cure hemorrhoid.The 2nd kind is operative treatment, and major defect is that the patient is very painful, be difficult for being accepted, and the easily recurrence of operation back, and leave sequela.The 3rd kind is injection treatment, also can only be relief of symptoms, can not effect a radical cure hemorrhoid.
The inventor lacks according to falling into of above-mentioned Therapeutic Method, through studying intensively for many years, has invented a kind of above-mentioned three kinds of Therapeutic Method, i.e. preparation method of oral haemorrhoids drug of being different from fully.Through clinical practice, confirmation be a kind of easy, patient is easy to accept, effective oral haemorrhoids drug.
The prescription that the inventive method is used, its Main Ingredients and Appearance are vitamin C, Citrin and alpha-tocopherol acetate, the tartaric acid of other adjuvants such as antioxidant.The magnesium stearate that starch that the agent of powder knot is used and granulate agent are used.
Look on the pharmacopeia and illustrate:
Ascorbic function is the attenuating capillary fragility, increases the human body resistance, promotes effects such as wound heals.
The function of Citrin is to reduce fragility capillaceous and permeability, suppresses the effect such as hemorrhage grade of blood capillary.
The function of alpha-tocopherol acetate is to improve effects such as muscular dystrophy, the metabolism of promotion flesh.
The inventor is in view of the property function that is had of said vitamin C, E, P and cooperate formed effect, after soon these three kinds of medicines will cooperate by a certain percentage, can bring into play sterilization, antiinflammatory, pain relieving, functions such as hemostasis, detumescence, prove through clinical practice repeatedly, three kinds of oral haemorrhoids drugs that main component is formed thus have the effect of beyond thought radical cure hemorrhoid.No matter be internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, anus is attacked and anus patients such as anal fistula can prove effective.
Now, be described in down the preparation method of oral haemorrhoids drug of the present invention:
Prescription: with 10,000 oral haemorrhoids sheets of every system meter
Vitamin c powder 1,000-1,600 grams
Citrin powder 200-350 gram
Alpha-tocopherol acetate 50-80 gram
Starch 680-1400 gram
Tartaric acid 8-12 gram
Magnesium stearate 40-60 gram
Dextrin 250-350 gram.
The step of preparation is:
(1) preparation of vitamin C and P mixed powder.
The vitamin C of above-mentioned scope and P powder and starch are put into universal mixer, start to stir and carry out dry blending, move into then and be milled to 80 purpose granularities in the general grater.And in addition tartaric acid is dissolved in 50% the ethanol, add this mangcorn powder and stir evenly.
(2) take by weighing alpha-tocopherol acetate.
(3) pelletize
The acetic acid rope E that supports one's family adds in the mixer fill in the plain C of dimension, the P mixed powder, stirs, and adds quantitative dextrin again, mixes thoroughly, makes suitable soft material with 60% ethanol.Granulate again by 20 mesh sieves with general granulation machine.
(4) oven dry
To make particulate material and put into general drying baker, under 60 ℃ temperature, dry.
(5) in dried granules, add magnesium stearate, cross 16 mesh sieve granulate.
(6) tabletting
In general tablet machine compacting in flakes.
Oral haemorrhoids drug of the present invention has following effect.
(1) many effects; Have relieve the pain, hemostasis, repercussive effect.
(2) curative effect is fast; Use this medicine can cure 2 courses of treatment continuously, be 2 week each course of treatment.
(3) cure rate height; In 200 many cases of having treated, cure rate is 100%, and none example is invalid.
(4) once radical cure; From beginning applying clinical time more than 2 years so far, no case was recurrence.
(5) easy to use: this product is oral, every heavy 0.3 gram.Every day 3 times, each 2.
(6) have no side effect.
With embodiment the present invention is done detailed explanation below.
Embodiment 1
A, vitamin c powder 1200 gram, Citrin powder 240 grams, starch 1200 grams are put into universal mixer, start and stirred 10 minutes, move into then and be milled to 80 order granularities in the general grater, sieve, 10 gram tartaric acid are dissolved in 10 milliliter of 50% ethanol and add in this mangcorn powder stand-by.
B, a and two kinds of materials of alpha-tocopherol acetate are being mixed in the mixer usually, adding dextrin 250 grams again, restraining 60% ethanol with 100 and be made into soft material.
C, then this soft material is placed common baking oven, under 60 ℃, dried 110 minutes.
D, taking-up oven dry material add magnesium stearate 50 grams and carry out pelletize, and last (f) is tabletting in general tablet machine, and sheet weighs 0.3 and restrains, and every content is by analysis
100 milligrams of vitamin Cs
5 milligrams of vitamin Es
20 milligrams of Citrins
Embodiment 2
The amount of removing following raw materials according changes into
Vitamin c powder 1440 grams
Citrin powder 300 grams
Starch 710 grams
Tartaric acid 12 grams
Alpha-tocopherol acetate 72 grams
Dextrin 300 grams
Ethanol 60% 100 grams
Outside magnesium stearate 55 grams, its process conditions are identical with example 1.Every in the tablet that makes heavily is 0.3 gram, and every content is:
120 milligrams of vitamin Cs
6 milligrams of vitamin Es
24 milligrams of Citrins
Clinical application effect
(1) certain woman, 54 years old, the workman suffered from inside and outside mixed hemorrhoid more than 20 year, with hibitane hemorrhoid suppository for many years, was interrupted recurrence therebetween.When recurring whenever, the hemorrhoid enlargement, stool band blood, sharp ache is shouted frequently, and not only patient but also household are also very painful.Take tablet every day 3 times of embodiment 1, each 2 dosage, take this medicine after 1 week, pain relief, stool band blood obviously reduces, and hemorrhoid are dwindled.Take medicine continuously and fully recover after 4 weeks.
(2) certain woman, 28 years old, nurse, the future trouble of bearing child hemorrhoid.Stool band blood is many, the hemorrhoid enlargement, and pain is unbearably.By after 4 week of dosage medication of above-mentioned the 1st example, cure fully.
(3) certain man, 62 years old, the retired veteran cadre just suffered from hemorrhoid.Stool band blood, hemorrhoid enlargement, pain.Take the tablet of embodiment 2, every day 3 times, each 2.After 3 week of medication, cure fully.
(4) certain man, 63 years old, the retired veteran cadre suffered from inside and outside mixed hemorrhoid more than 10 year, once did operation in 301 Hospital of the Chinese People's Liberation Army.Have secretions to flow out during the postoperative anus, patient is very painful.Take the tablet of embodiment 2, every day 3 times, after each 21 week, the secretions discharge reduces, and cures fully after 4 week.
Claims (1)
1, a kind of preparation method of oral haemorrhoids drug is characterized in that this method comprises the steps, will
Vitamin c powder 1000-1600 gram
Citrin powder 200-350 gram
Alpha-tocopherol acetate 50-80 gram
Starch 680-1400 gram
Tartaric acid 8-12 gram
Magnesium stearate 40-60 gram
Dextrin 250-350 gram
Mixing, pelletize, oven dry, granulate, tabletting.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN91111946A CN1038303C (en) | 1991-12-30 | 1991-12-30 | Process for preparing high efficient oral haemorrhoids drug |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN91111946A CN1038303C (en) | 1991-12-30 | 1991-12-30 | Process for preparing high efficient oral haemorrhoids drug |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1061906A CN1061906A (en) | 1992-06-17 |
| CN1038303C true CN1038303C (en) | 1998-05-13 |
Family
ID=4910932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN91111946A Expired - Fee Related CN1038303C (en) | 1991-12-30 | 1991-12-30 | Process for preparing high efficient oral haemorrhoids drug |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1038303C (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2212722A (en) * | 1987-11-25 | 1989-08-02 | Theravit Limited | Vitamin compositions |
| EP0343694A2 (en) * | 1984-03-07 | 1989-11-29 | Roshdy Dr. Ismail | Agent for the treatmment and protection of the skin |
-
1991
- 1991-12-30 CN CN91111946A patent/CN1038303C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0343694A2 (en) * | 1984-03-07 | 1989-11-29 | Roshdy Dr. Ismail | Agent for the treatmment and protection of the skin |
| GB2212722A (en) * | 1987-11-25 | 1989-08-02 | Theravit Limited | Vitamin compositions |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1061906A (en) | 1992-06-17 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |