CN103830392A - Swelling-diminishing pain-relieving medicine and preparation method thereof - Google Patents

Swelling-diminishing pain-relieving medicine and preparation method thereof Download PDF

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CN103830392A
CN103830392A CN201410101385.0A CN201410101385A CN103830392A CN 103830392 A CN103830392 A CN 103830392A CN 201410101385 A CN201410101385 A CN 201410101385A CN 103830392 A CN103830392 A CN 103830392A
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radix
medicine
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blood
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CN103830392B (en
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匡如
任桂萍
王勤学
孙全伟
吕希峰
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JIAOZHOU PEOPLE'S TRADITIONAL CHINESE MEDICINE HOSPITAL
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JIAOZHOU PEOPLE'S TRADITIONAL CHINESE MEDICINE HOSPITAL
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Abstract

The invention belongs to the technical field of traditional Chinese medicines and particularly relates to a swelling-diminishing pain-relieving medicine and a preparation method thereof. The swelling-diminishing pain-relieving medicine comprises the following components in parts by weight: 75 parts of red sage root, 75 parts of red peony root, 37.5 parts of costus root, 37.5 parts of dried ground beetle, 2 parts of borneol, 37.5 parts of rhizoma corydalis, 7.5 parts of green tangerine peel, 22.5 parts of rhubarb, 5.5 parts of panax notoginseng and 75 parts of angelica sinensis. The medicine is based on the qi and blood differentiation theory of traditional Chinese medicine and combined with modern pharmacological research and comprises the raw medicines such as red sage root, angelica sinensis, panax notoginseng, dried ground beetle and rhizoma corydalis, so that the medicine has the remarkable efficacies of activating blood and removing stasis, diminishing swelling and relieving pain; proved by clinic applications, and the medicine is obvious in treatment effect; the medicine is a pure traditional Chinese medicine preparation and is free of obvious toxic or side effect; the patent medicine is capable of realizing one-time mass production and is convenient to carry and take.

Description

A kind of reducing swelling and alleviating pain medicine and preparation method
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of reducing swelling and alleviating pain medicine and preparation method.
Background technology
The traditional Chinese medical science is thought: qi being the governor of blood, blood being the material foundation of QI, the capable blood of gas arrives, blood to the whole body as pass through, YIN and YANG balancing, healthy.If limbs injured, congestion retardance, QI-blood circulation is not smooth; " stagnation of QI and blood may bring about pain, general rule is not swollen ".Treatment is main with " blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain ", and congestion goes fresh blood life, QI and blood and suitable, " general rule is not bitterly ".
Swell and ache and mainly contain three sevens kinds of impairments for post-traumatic tissue, be main or the treatment of application Western medicine nonsteroidal reducing swelling and alleviating pain Deng treatment by Chinese herbs, unsatisfactory curative effect, and the side effect of western medicine and medical practitioners nonsteroidal is large, especially can cause the complication that upper digestive tract is serious, somewhat expensive, and long-time application can cause the important organ infringements such as Drug Liver and kidney.
Summary of the invention
The object of the invention is to overcome above-mentioned technical problem and provide a kind of side effect little, easy to carry, eutherapeutic reducing swelling and alleviating pain medicine.
For achieving the above object, the present invention adopts following technical scheme:
A kind of reducing swelling and alleviating pain medicine, comprises following component by weight: Radix Salviae Miltiorrhizae 75 weight portions, Radix Paeoniae Rubra 75 weight portions, the Radix Aucklandiae 37.5 weight portions, eupolyphaga 37.5 weight portions, Borneolum Syntheticum 2 weight portions, Rhizoma Corydalis 37.5 weight portions, Pericarpium Citri Reticulatae Viride 7.5 weight portions, Radix Et Rhizoma Rhei 22.5 weight portions, Radix Notoginseng 5.5 weight portions, Radix Angelicae Sinensis 75 weight portions.
A preparation method for described reducing swelling and alleviating pain medicine, comprises the following steps:
(1) Radix Notoginseng, the Radix Aucklandiae, eupolyphaga, Rhizoma Corydalis, Pericarpium Citri Reticulatae Viride, Radix Et Rhizoma Rhei powder are broken into fine powder and cross 100 mesh sieves, mix for subsequent use;
(2) Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Radix Angelicae Sinensis are decocted with water to twice, each 2 hours, collecting decoction, filtered, and it is for subsequent use that filtrate is concentrated into into paste spice;
(3) paste spice in step 2 is added to the fine powder in step 1, mix, dry, pulverize into fine powder, cross 100 mesh sieves;
(4) borneol and grinding, crosses 80 mesh sieves, mixes with the fine powder in equivalent incremental method and above-mentioned steps 3, incapsulates, and after ethane via epoxyethane sterilizing, places 7~10 days, can obtain described reducing swelling and alleviating pain medicine.
We are according to traditional Chinese medical science differentiation of syndromes according to pathogeneses of QI and blood theory, in conjunction with modern pharmacological research, use the ingredients prescriptions such as Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Radix Notoginseng, eupolyphaga, Rhizoma Corydalis, there is the curative effect of significant blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, obvious through clinical practice curative effect, and be pure Chinese medicinal preparation, without obvious toxic-side effects, making patent medicine can disposablely produce in enormous quantities, carries taking convenience.
Function cures mainly: blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.
Indication: the disease such as swell and ache causing for each position congestion retardance, soft tissue injury.
Etiology and pathogenesis: the traditional Chinese medical science is thought: qi being the governor of blood, blood being the material foundation of QI, the capable blood of gas arrives, blood to the whole body as pass through, YIN and YANG balancing, healthy.If limbs injured, congestion retardance, QI-blood circulation is not smooth; " stagnation of QI and blood may bring about pain, general rule is not swollen ".
The rule for the treatment of: blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.
Medication principle
1, Radix Salviae Miltiorrhizae: bitter in the mouth, micro-pungent, cold nature, the medicine of the heart, spleen, liver, kidney blood system; Cure mainly blood stasis head, breast, the side of body, abdomen pain, gather, menoxenia, dysmenorrhea amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, arthralgia, traumatic injury congestive edema, epidemic febrile disease is vexed, palpitation due to deficiency of blood, sore swollen toxin.
2, Radix Paeoniae Rubra: Radix Paeoniae Rubra bitter in the mouth, cool in nature, there is effect of blood stasis dispelling, pain relieving, removing heat from blood, detumescence.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, carbuncle skin infection.The Radix Paeoniae Rubra point excess-heat that can purify the blood, dissipating blood stasis blood is detained.Can only be used for blood system excess-heat, be good at promoting blood circulation to remove blood stasis.Control the stagnant amenorrhea of the stasis of blood, hernia abdominal mass is gathered, stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle.For epidemic febrile disease, heat enters nutrient blood, heating, crimson tongue, body and sends out macule, and bleeding due to blood-heat etc.
3, the Radix Aucklandiae: pungent acrid in the mouth; Bitter; Warm in nature.Gui Jing: return spleen; Large intestine, tri-jiao channel.Effect: circulation of qi promoting, pain relieving, spleen invigorating, helps digestion and cures mainly: promoting the circulation of QI to relieve pain; Intestinal stasis relieving in tune.Main born of the same parents coerce distension foot; Abdominal distention; Tell and have loose bowels; Heavy after dysentery.For heavy after breast gastral cavity distending pain, dysentery, food stagnation does not disappear, anorexia; Middle gas is not economized; Burst is deaf; Snake bite and insect sting; Toothache.
4, eupolyphaga: source: this product is the female worm dry body of Corydiidae insecticide eupolyphoge sinensis or Ji eupolyphoge sinensis.After seizure, put in boiling water and scald extremely, dry or dry.Nature and flavor with return through: salty, cold; Slightly poisonous.Return Liver Channel.Function with cure mainly: removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.Attention: anemia of pregnant woman's forbidding.
5, Borneolum Syntheticum: the resin and the volatile oil processed goods that are Spore density Borneolum Syntheticum extract the crystallization obtaining, and acrid in the mouth hardship, is slightly cold.Enter the heart, Liver Channel.GUIXIN, liver, lung meridian; The loose poison of heat clearing away, effect of improving acuity of vision and removing nebula, cures mainly calentura unconsciousness due to high fever, apoplexy syncope due to accumulation of phlegm infantile convulsion, heat-damp in summer is hoodwinked key clearly, sore throat deafness, aphtha tooth is swollen.
6, Rhizoma Corydalis: warm in nature for Papaveraceae Corydalis herbaceos perennial, acrid in the mouth hardship, enters the heart, spleen, liver, lung, is the quality goods of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, is especially world-famous for effect of pain relieving.There are " invigorate blood circulation, regulate the flow of vital energy, pain relieving, diuresis " four large effects, and praise highly Rhizoma Corydalis " stagnation of QI in energy promoting the circulation of blood, stasis in gas, therefore specially control upper and lower all pains all over the body ".Rhizoma Corydalis acrid in the mouth, hardship, warm in nature.There is promoting blood circulation to remove blood stasis, the function of regulating QI to relieve pain.Cure mainly usage for pain of the each portion of whole body qi depression to blood stasis, dysmenorrhea, amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia is had a pain.
7, Pericarpium Citri Reticulatae Viride: rectification of name: Armeniaca mume Sieb., nature and flavor hardship, pungent, temperature.Gui Jing returns liver, gallbladder, stomach warp.Function cures mainly soothing the liver dispelling the stagnated QI; Removing food stagnancyization is stagnant.The distending pain over the hypochondrium of main stagnation of QI due to depression of the liver; Distending pain of the breast; Nodule in the breast; Acute mastitis; Hernia pain; The epigastric distending pain of stagnation of QI due to dyspepsia; And qi depression to blood stasis lump in the abdomen extremely; Chronic malaria addiction piece.
8, Radix Et Rhizoma Rhei: nature and flavor: hardship, cold.Gui Jing: spleen, stomach, large intestine, liver, pericardium channel.Effect: attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Removing toxic substances.Cure mainly: excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; Edema abdominal distention; Dysuria;
9, Radix Notoginseng: sweet, the micro-hardship of nature and flavor, temperature.Gui Jing returns liver, stomach warp.Function cures mainly: tuber: activating blood and removing stasis, hemostasis, reducing swelling and alleviating pain.For epistaxis, spit blood, spitting of blood, has blood in stool, dysfunctional uterine hemorrhage, puerperal abdominal pain due to blood stasis, traumatic injury.Flower: heat clearing away, suppressing the hyperactive liver, blood pressure lowering.For acute pharyngolaryngitis, giddy, dizzy, tinnitus.Attention: anemia of pregnant woman is cautious use of.
10, Radix Angelicae Sinensis: sweet in the mouth and weighing, therefore specially can enrich blood, its gas is light and pungent, thus again can promoting the circulation of blood, invigorating middle warmer has, in row, has benefit, is the key medicine in blood.Thereby it can be enriched blood, can invigorate blood circulation again, both can stimulate the menstrual flow, again can be active.All menoxenias, dysmenorrhea, blood deficiency amenorrhea, shallow complexion, weak anemia, metrorrhagia, postnatal blood stasis, example, through women's such as (when menstrual onsets, occur mouth and nose bleed) commonly encountered diseases, can be used angelica for treating.
We's syndrome of controlling, wound injured, or feelings will is not smooth, causes body QI-blood circulation to be obstructed, stagnation of QI and blood, the stagnation of QI is general rule pain not, congestion retardance is raw lump, blood oozing from the body openings or subcuta neous tissue in outside, give birth to ecchymosis.Treatment is with blood circulation promoting and blood stasis dispelling, and promoting the circulation of QI to relieve pain are method, QI and blood and suitable swelling and ache from disappearing.Therefore side use Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, removing heat from blood to disappear bitterly, nourishing blood to tranquillize the mind, inside reaches internal organs blood stasis dispelling stagnant, outer sharp joint and promoting blood circulation.Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving.Radix Notoginseng is the key medicine for the treatment of traumatology, and Removing Blood Stasis and do not hinder fresh blood, is treating blood disorders quality goods.Radix Et Rhizoma Rhei can descend congestion, blood to close, removing blood stasis, Rhizoma Corydalis promoting the circulation of QI to relieve pain, the stagnation of QI in energy promoting the circulation of blood, stasis in gas, compatibility Radix Paeoniae Rubra removing heat from blood and promoting blood circulation, Radix Aucklandiae regulating QI to remove the stagnation, warming middle-JIAO for easing the stomach, eupolyphaga removing mass removing blood stasis, reunion of fractured tendons and bones, Borneolum Syntheticum have one's ideas straightened out eye-catching eliminating stasis to stop pain, Rhizoma Corydalis, Pericarpium Citri Reticulatae Viride promoting the circulation of QI to relieve pain, stomach invigorating and in.
The specific embodiment
Below, in conjunction with example, substantive distinguishing features of the present invention and advantage are further described, but the present invention is not limited to listed embodiment.
Embodiment
A kind of reducing swelling and alleviating pain medicine, comprises following component by weight: Radix Salviae Miltiorrhizae 75 weight portions, Radix Paeoniae Rubra 75 weight portions, the Radix Aucklandiae 37.5 weight portions, eupolyphaga 37.5 weight portions, Borneolum Syntheticum 2 weight portions, Rhizoma Corydalis 37.5 weight portions, Pericarpium Citri Reticulatae Viride 7.5 weight portions, Radix Et Rhizoma Rhei 22.5 weight portions, Radix Notoginseng 5.5 weight portions, Radix Angelicae Sinensis 75 weight portions.
A preparation method for described reducing swelling and alleviating pain medicine, comprises the following steps:
(1) Radix Notoginseng, the Radix Aucklandiae, eupolyphaga, Rhizoma Corydalis, Pericarpium Citri Reticulatae Viride, Radix Et Rhizoma Rhei powder are broken into fine powder and cross 100 mesh sieves, mix for subsequent use;
(2) Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Radix Angelicae Sinensis are decocted with water to twice, each 2 hours, collecting decoction, filtered, and it is for subsequent use that filtrate is concentrated into into paste spice;
(3) paste spice in step 2 is added to the fine powder in step 1, mix, dry, pulverize into fine powder, cross 100 mesh sieves;
(4) borneol and grinding, crosses 80 mesh sieves,, mix with the fine powder in equivalent incremental method and above-mentioned steps 3, pack capsule into No. 0, every contains medicated powder 0.3 weight portion, after ethane via epoxyethane sterilizing, places 7~10 days, can obtain described reducing swelling and alleviating pain medicine, subpackage, 60/bottle.
Function of the present invention cures mainly: blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.The disease such as swell and ache causing for the retardance of each position congestion, soft tissue injury.
Usage and dosage: each 6~8 every day three times, 20 days is a course for the treatment of, anemia of pregnant woman's forbidding.
Clinical data
Give reducing swelling and alleviating pain medicine to 200 routine traumatic patients and treat 2 weeks, compared with matched group (ibuprofen and three seven kinds of impairments sheets)
The curative effect for the treatment of traumatic swollen tissue reducing swelling and alleviating pain medicine and ibuprofen, three sevens kinds of impairments relatively sees the following form:
Group Swelling regression time/sky
Treatment group (reducing swelling and alleviating pain medicine) 7.5±2.3
Matched group 1(tri-sevens kinds of impairments) 11.7±3.1
Matched group 2(ibuprofen) 12.6±3.3
Learn and process P < 0.05 by statistics, there were significant differences.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.

Claims (2)

1. a reducing swelling and alleviating pain medicine, it is characterized in that, comprise following component by weight: Radix Salviae Miltiorrhizae 75 weight portions, Radix Paeoniae Rubra 75 weight portions, the Radix Aucklandiae 37.5 weight portions, eupolyphaga 37.5 weight portions, Borneolum Syntheticum 2 weight portions, Rhizoma Corydalis 37.5 weight portions, Pericarpium Citri Reticulatae Viride 7.5 weight portions, Radix Et Rhizoma Rhei 22.5 weight portions, Radix Notoginseng 5.5 weight portions, Radix Angelicae Sinensis 75 weight portions.
2. a preparation method for reducing swelling and alleviating pain medicine described in claim 1, is characterized in that, comprises the following steps:
(1) Radix Notoginseng, the Radix Aucklandiae, eupolyphaga, Rhizoma Corydalis, Pericarpium Citri Reticulatae Viride, Radix Et Rhizoma Rhei powder are broken into fine powder and cross 100 mesh sieves, mix for subsequent use;
(2) Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Radix Angelicae Sinensis are decocted with water to twice, each 2 hours, collecting decoction, filtered, and it is for subsequent use that filtrate is concentrated into into paste spice;
(3) paste spice in step 2 is added to the fine powder in step 1, mix, dry, pulverize into fine powder, cross 100 mesh sieves;
(4) borneol and grinding, crosses 80 mesh sieves, mixes with the fine powder in equivalent incremental method and above-mentioned steps 3, incapsulates, and after ethane via epoxyethane sterilizing, places 7~10 days, can obtain described reducing swelling and alleviating pain medicine.
CN201410101385.0A 2014-03-19 2014-03-19 A kind of reducing swelling and alleviating pain medicine and preparation method Expired - Fee Related CN103830392B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1241419A (en) * 1998-07-02 2000-01-19 袁方 Fangzheng fracture-setting pain relieving ointment
CN1502350A (en) * 2002-11-22 2004-06-09 高庆刚 Traditional Chinese medicine composition (Fujangtieda liquor) for curing traumatic injury
CN101612233A (en) * 2009-07-31 2009-12-30 徐学农 A kind of Chinese medicine preparation of reducing swelling and alleviating pain

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1241419A (en) * 1998-07-02 2000-01-19 袁方 Fangzheng fracture-setting pain relieving ointment
CN1502350A (en) * 2002-11-22 2004-06-09 高庆刚 Traditional Chinese medicine composition (Fujangtieda liquor) for curing traumatic injury
CN101612233A (en) * 2009-07-31 2009-12-30 徐学农 A kind of Chinese medicine preparation of reducing swelling and alleviating pain

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Inventor after: Kuang Xiaowen

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