CN103815946A - Non-cranium-drill cranial ridge punching device for big and small mice - Google Patents

Non-cranium-drill cranial ridge punching device for big and small mice Download PDF

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Publication number
CN103815946A
CN103815946A CN201410074457.7A CN201410074457A CN103815946A CN 103815946 A CN103815946 A CN 103815946A CN 201410074457 A CN201410074457 A CN 201410074457A CN 103815946 A CN103815946 A CN 103815946A
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CN
China
Prior art keywords
needle body
cranium
body connecting
drill
threaded rod
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410074457.7A
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Chinese (zh)
Inventor
祁金顺
张军
张升校
马小雯
张雨薇
李玉峰
武美娜
杨威
王昭君
蔡红艳
原丽
仝嘉庆
郝明
陈建鸣
陈晋原
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Shanxi Medical University
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Shanxi Medical University
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Publication date
Application filed by Shanxi Medical University filed Critical Shanxi Medical University
Priority to CN201410074457.7A priority Critical patent/CN103815946A/en
Publication of CN103815946A publication Critical patent/CN103815946A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/16Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans
    • A61B17/1695Trepans or craniotomes, i.e. specially adapted for drilling thin bones such as the skull
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00Evaluating a particular growth phase or type of persons or animals
    • A61B2503/40Animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00Evaluating a particular growth phase or type of persons or animals
    • A61B2503/42Evaluating a particular growth phase or type of persons or animals for laboratory research

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dentistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

The invention belongs to the technical field of medical equipment, and particularly relates to a non-cranium-drill cranial ridge punching device for big and small mice, which mainly aims to solve the problems that when a traditional electric cranium drill is used for craniotomy, the pore diameter is difficult to adjust, the depth is uncontrollable, cerebral concussion can be easily caused due to the craniotomy carried out by the traditional electric cranium drill, and the like. The invention has the technical scheme that the non-cranium-drill cranial ridge punching device for the big and small mice comprises a handle, a fixing sleeve, an adjusting nut, a protection sleeve, a needle body connecting part, a needle body connecting petal, a fixing rod, a threaded rod and a needle body, wherein the needle body connecting part is arranged at the lower end of the handle, the needle body connecting petal is arranged at the lower end of the needle body connecting part, the upper end of the fixing rod is connected with the needle body connecting petal, the lower end of the fixing rod is connected with the upper end of the threaded rod, the lower end of the threaded end is connected with the needle body, the fixing sleeve is sleeved on the needle body connecting part, the adjusting nut and the protection sleeve are arranged on the threaded rod, and the adjusting nut is positioned above the protection sleeve. The non-cranium-drill cranial ridge punching device for the big and small mice, disclosed by the invention, has the advantages that the pore diameter is adjustable, the depth is controllable, the damage is low, and the operation is simple.

Description

The non-cranium of a kind of large mice bores skull boring device
Technical field
The invention belongs to armarium technical field, be specifically related to the non-cranium of a kind of large mice and bore skull boring device.
Background technology
The operation of opening cranium of large and small Mus is necessity operation of the administration of experimental mouse intracranial and Electrophysiology experimental record.Traditional electronic cranium bores opens the not only very difficult size that regulates the skull aperture of opening of cranium method, and the uncontrollable electric drill degree of depth, easily causes intracranial infection and brain tissue impairment; Electric drill can, to a Mus random concussion, cause the neurocyte of Mus intracranial and nerve fiber inevitably to be damaged, thereby affect the brain function of experimental mouse simultaneously, has strengthened the mortality rate of Mus, very unfavorable to experimental result.
Summary of the invention
The present invention has out the difficult adjusting in cranium aperture, the uncontrollable degree of depth, easy damaged cerebral tissue mainly for the operation of opening cranium that adopts conventional electric cranium to creep into the large mice of row, when cranium left by electric drill, cause cerebral concussion, affect the problems such as experimental result, provide a kind of simple, effectively, Wicresoft, aperture is controlled, the degree of depth is adjustable non-cranium bore skull boring device, to reduce the damage of experimental mouse brain, thereby meet the needs of intracranial administration and Electrophysiology record.
The present invention addresses the above problem the technical scheme of taking to be:
The non-cranium of a kind of large mice bores skull boring device, comprise hands handle, wherein: also comprise fixed cover, adjusting nut, protective sleeve, needle body connecting portion, needle body connects lobe, fixed bar, threaded rod and needle body, described needle body connecting portion is located at the lower end of handle, needle body connection lobe is located at the lower end of needle body connecting portion, the upper end of fixed bar is connected lobe with needle body and is connected, the lower end of fixed bar is connected with the upper end of threaded rod, the lower end of threaded rod is connected with needle body, fixed cover is enclosed within on needle body connecting portion, adjusting nut and protective sleeve are all located on threaded rod and adjusting nut is positioned at the top of protective sleeve.
The needle point of described needle body lower end be shaped as the taper of concave surface Rhizoma Sparganii.
The outer surface of described handle is provided with striped.
The present invention adopts technique scheme, fixed bar and needle body are connected employing between lobe and are flexibly connected, and the needle body being connected from fixed bar has different specifications, so just can select applicable needle body according to concrete requirement of experiment, and then control the pore size of perforate; Protective sleeve can effectively be controlled the skull perforate degree of depth, avoids crossing the dark damage to cerebral tissue because of perforate; Needle point is the taper of concave surface Rhizoma Sparganii, and light ground auger is opened skull fast, reduces experimental mouse cerebral hemorrhage and cerebral concussion, and then guarantees the accuracy of experimental result.Therefore, compared with prior art, the present invention has the following advantages: that 1, can select different size opens cranium pin, thereby controls the size of opening cranium aperture; 2, can accurately regulate the height of protective sleeve, control the degree of depth of skull perforate, while avoiding out cranium, cross dark injured brain tissue; 3, Wicresoft manually opens cranium operation, reduces Mus cerebral concussion and wound surface damage, accelerating wound healing; 4, install simple to operation, improve operation efficiency; 5, device is light and handy, and portable, cost is low.
Accompanying drawing explanation
Fig. 1 is structural representation of the present invention;
Fig. 2 is the structural representation of handle of the present invention;
Fig. 3 is the structural representation of needle body of the present invention;
Fig. 4 is the structural representation that needle body of the present invention connects lobe;
Fig. 5 is the structural representation of needle point of the present invention.
The specific embodiment
Embodiment 1
As shown in Figures 1 to 5, the non-cranium of a kind of large mice bores skull boring device, comprise handle 1, wherein: also comprise fixed cover 2, adjusting nut 3, protective sleeve 4, needle body connecting portion 5, needle body connects lobe 10, fixed bar 6, threaded rod 7 and needle body 8, be provided with nicking 11 at the outer surface of handle 1, described needle body connecting portion 5 is located at the lower end of handle 1, needle body connection lobe 10 is located at the lower end of needle body connecting portion 5, the upper end of fixed bar 6 is inserted needle body and is connected in lobe 10, the lower end of fixed bar 6 is connected with the upper end of threaded rod 7, the lower end of threaded rod 7 is connected with needle body 8, the needle point 9 of needle body 8 lower ends is the taper of concave surface Rhizoma Sparganii, fixed cover 2 is enclosed within on needle body connecting portion 5, adjusting nut 3 and protective sleeve 4 are all located on threaded rod 7 and adjusting nut 3 is positioned at the top of protective sleeve 4.
Concrete operation step is as follows:
The first step: experimental needs, determine the pore size of required skull perforate, and select the needle body of respective model;
Second step: the fixed bar of needle body is inserted to needle body and connect in lobe, and with fixed cover, it is spiral fixing;
The 3rd step: regulate adjusting nut and the position of protective sleeve on threaded rod, thereby determine needle body open the cranium degree of depth;
The 4th step: by rotary handle, open cranium to anaesthetizing fixing large mice.
Below by specific experiment, invention is described in detail technical scheme of the present invention in order further to explain.
For example wish is by the cranium of opening before SD rat (body weight 250g) intracranial hippocampal injection administration.Because the diameter of administration needle is 0.38mm, the diameter 0.5mm of required skull perforate is advisable, and is that to be 0.3mm open cranium pin for 0.5mm, needle point height therefore can select needle body diameter.The needle body that the fixed bar of opening cranium pin is inserted to handle connects in lobe, and with fixed cover, it is spiral fixing.Install and regulate adjusting nut and protective sleeve; opening cranium because of this not only needs brill to open skull; also need to puncture cerebral dura mater; to enter smoothly administration with administration needle; rule of thumb, the relative distance of protective sleeve and needle point is adjusted to about 1.2mm left and right, passes through rotary handle; in the relevant position of anaesthetizing fixing rat skull, (3.0mm after Bregma, the other 2.2mm that opens of center line) opens cranium.

Claims (3)

1. the non-cranium of large mice bores skull boring device, comprise handle (1), it is characterized in that: also comprise fixed cover (2), adjusting nut (3), female protective sleeve (4) is established in inner side, needle body connecting portion (5), needle body connects lobe (10), fixed bar (6), threaded rod (7) and needle body (8), described needle body connecting portion (5) is located at the lower end of handle (1), needle body connection lobe (10) is located at the lower end of needle body connecting portion (5), the upper end of fixed bar (6) is connected lobe (10) and is connected with needle body, the lower end of fixed bar (6) is connected with the upper end of threaded rod (7), the lower end of threaded rod (7) is connected with needle body (8), fixed cover (2) is enclosed within on needle body connecting portion (5), adjusting nut (3) and protective sleeve (4) are all located at the upper and adjusting nut (3) of threaded rod (7) and are positioned at the top of protective sleeve (4).
2. the non-cranium of the large mice of one according to claim 1 bores skull boring device, it is characterized in that: the needle point (9) of described needle body (8) lower end be shaped as the taper of concave surface Rhizoma Sparganii.
3. the non-cranium of the large mice of one according to claim 1 bores skull boring device, it is characterized in that: the outer surface of described handle (1) is provided with striped (11).
CN201410074457.7A 2014-03-03 2014-03-03 Non-cranium-drill cranial ridge punching device for big and small mice Pending CN103815946A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410074457.7A CN103815946A (en) 2014-03-03 2014-03-03 Non-cranium-drill cranial ridge punching device for big and small mice

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410074457.7A CN103815946A (en) 2014-03-03 2014-03-03 Non-cranium-drill cranial ridge punching device for big and small mice

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CN103815946A true CN103815946A (en) 2014-05-28

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105496500A (en) * 2015-12-14 2016-04-20 黄少安 Ceramic drill
CN109512482A (en) * 2017-09-20 2019-03-26 王力平 A kind of spacing collar trepan
CN110946628A (en) * 2020-01-06 2020-04-03 西藏新好科技有限公司 Tissue medical treatment sampler for livestock

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4821716A (en) * 1987-09-04 1989-04-18 Neurodynamics, Inc. Method and apparatus for perpendicular perforation of the cranium
CN2284600Y (en) * 1996-12-02 1998-06-24 昌乐县人民医院 Safety cranial trepan
CN2287907Y (en) * 1996-03-30 1998-08-19 秦怀海 Removable cranial bone awl
WO2010093712A2 (en) * 2009-02-10 2010-08-19 Innerspace Medical, Inc. Bolt stop system for use in accessing intracranial space
CN203749495U (en) * 2014-03-03 2014-08-06 山西医科大学 Rat and mouse non-cranium-drilling cranium trepanning device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4821716A (en) * 1987-09-04 1989-04-18 Neurodynamics, Inc. Method and apparatus for perpendicular perforation of the cranium
CN2287907Y (en) * 1996-03-30 1998-08-19 秦怀海 Removable cranial bone awl
CN2284600Y (en) * 1996-12-02 1998-06-24 昌乐县人民医院 Safety cranial trepan
WO2010093712A2 (en) * 2009-02-10 2010-08-19 Innerspace Medical, Inc. Bolt stop system for use in accessing intracranial space
CN203749495U (en) * 2014-03-03 2014-08-06 山西医科大学 Rat and mouse non-cranium-drilling cranium trepanning device

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105496500A (en) * 2015-12-14 2016-04-20 黄少安 Ceramic drill
CN109512482A (en) * 2017-09-20 2019-03-26 王力平 A kind of spacing collar trepan
WO2019057033A1 (en) * 2017-09-20 2019-03-28 王力平 Trephine having limiting sleeve
CN110946628A (en) * 2020-01-06 2020-04-03 西藏新好科技有限公司 Tissue medical treatment sampler for livestock

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Application publication date: 20140528