CN103812232A - Wireless passive implantable medical treatment device based on voltage feedback and control method for same - Google Patents

Wireless passive implantable medical treatment device based on voltage feedback and control method for same Download PDF

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CN103812232A
CN103812232A CN201410078943.6A CN201410078943A CN103812232A CN 103812232 A CN103812232 A CN 103812232A CN 201410078943 A CN201410078943 A CN 201410078943A CN 103812232 A CN103812232 A CN 103812232A
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voltage
circuit
voltage feedback
implantable medical
microprocessor
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CN103812232B (en
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张旭
李春婵
李刚
刘庆凯
任朝晖
白谦睿
闫立丽
刘斌
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Capital Medical University
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Capital Medical University
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Abstract

The invention discloses a wireless passive implantable medical treatment device based on voltage feedback and a control method for the same. The wireless passive implantable medical treatment device based on voltage feedback comprises an in-vitro controller and an in-vivo implantable medical treatment device, wherein the in-vitro controller comprises a first microprocessor, a PWM generator and a BUCK circuit; the in-vivo implantable medical treatment device comprises a voltage feedback circuit connected behind a rectification and filter circuit and connected with a medical treatment executer in parallel, the voltage feedback circuit is composed of two resistors which are connected in series, a tap is led out from the middle of the two resistors as the sampling end of an ADC, and the voltage feedback circuit is used for feeding the sampling voltage of the medical treatment executer back to the first microprocessor; the first microprocessor is used for adjusting the duty cycle of the output square wave of the PWM generator according to the sampling voltage, so as to control the output voltage of the BUCK circuit. The voltage feedback circuit is simple and low in energy consumption; the voltage feedback is increased during wireless energy transfer, and an energy emission level is capable of providing energy according to the load need of a receiving end, thus contributing to increase the effective utilization rate of energy and prolonging the service life of a system battery.

Description

Wireless and passive implantable medical device and control method thereof based on Voltage Feedback
Technical field
The present invention relates to wireless and passive implantable medical device energy supply technical field, particularly a kind of wireless and passive implantable medical device and control method thereof based on Voltage Feedback.
Background technology
Along with the development of microelectric technique and the raising of medical science level, implantable medical device obtains applying more and more widely, from cardiac pacemaker, brain degree of depth stimulator, SCS device to artificial cell and artificial organs etc.Implantable medical device manufacture craft is higher, prevailing price costliness.But at present, most implantable medical devices still rely on powered battery, limited by battery capacity, probably only have 3-5 useful life.Once battery exhausts, just need operation to change, this will bring tremendous economic burden to patient, also will bear wound and misery on health simultaneously.
Chinese invention patent " a kind of method of measurement of wireless and passive and circuit " (publication number: CN102003973A) discloses a kind of measuring circuit, consists of inside and outside two parts.In circuit, comprise outside and inner a pair of coil, external coil is internal circuit power supply by the mode of electromagnetic coupled, can realize without the human parameters under battery and measuring.Chinese invention patent " a kind of wireless and passive measurement mechanism " (publication number: CN102944259A) proposes a kind of wireless and passive measurement mechanism based on farad capacitor, alternating current on secondary coil is farad capacitor charging by charge management module after rectifying and wave-filtering and voltage stabilizing processing, uses for measuring circuit.
Above two kinds of embodiments all can be used for implantable medical human parameters to be measured, and implanted circuit part is not containing battery, can extend its useful life indefinite duration.But both external power supplies adopt firm power mode, capacity usage ratio is low, is not only a kind of waste to energy, also can reduce the life-span of externally fed battery, in the time that vivo and vitro coil-span changes, need manual adjustments transmitting terminal power in addition, use dumb.
Summary of the invention
The invention provides a kind of wireless and passive implantable medical device and control method thereof based on Voltage Feedback, the present invention is in the time of wireless power, by detecting the voltage condition of receiving terminal, adjust the power of transmitting terminal, can solve the low problem of capacity usage ratio in the power supply of wireless and passive implantable medical device, described below:
A kind of wireless and passive implantable medical device based on Voltage Feedback, comprise: external controller and vivo implantation type medical treatment device two parts, described external controller comprises: first microprocessor, PWM generator and BUCK circuit, described vivo implantation type medical treatment device comprises: voltage feedback circuit, described voltage feedback circuit is connected to current rectifying and wave filtering circuit afterwards and is in parallel with medical actuator
Described voltage feedback circuit is made up of the resistance of two series connection, in the middle of two resistance, draws the sampling end of tap as ADC, and the sampled voltage of described medical actuator is fed back to described first microprocessor by described voltage feedback circuit; Described first microprocessor
Regulate the duty ratio of described PWM generator output square wave according to described sampled voltage, to control described BUCK circuit output voltage size.
Described wireless and passive implantable medical device also comprises: rechargeable battery and charge management module,
Described charge management module is responsible for battery charging management and the electric weight situation of described rechargeable battery is fed back to described first microprocessor, and described first microprocessor control display module shows battery electric quantity.
Described wireless and passive implantable medical device also comprises: power amplification circuit and drive circuit,
Described power amplification circuit connects into full-bridge topologies by four N channel field-effect pipes, described power amplification circuit input is connected with described drive circuit output, described drive circuit drives chip or two half-bridge driven chips to form by a full-bridge, and described drive circuit input control signal is the full symmetric square wave of described first microprocessor output.
A control method for wireless and passive implantable medical device, is characterized in that, described control method comprises the following steps:
(1) the optimal voltage V of setting voltage feedback circuit sampling end aDP;
(2) obtain voltage difference Δ V aD=V aD-V aDP;
Wherein, V aD=R2/ (R1+R2) * V0, V0 is the direct voltage of current rectifying and wave filtering circuit output; R1, R2 are the voltage of series resistance, and R1+R2>10Ri, and R1, R2 resistance reasonable mixture ratio, make V aD<V1, Ri is late-class circuit input resistance; V1 is the output voltage of voltage stabilizing circuit; (3) according to described voltage difference and preset range [a, a], the duty ratio of PWM generator output square wave is controlled;
When | Δ V aD|-a<0 or | Δ V aD| when-a=0, D n=D n-1, Dn is the duty ratio of PWM generator output square wave while carrying out transmitting power adjustment for the n time, D n-1it is the duty ratio of PWM generator output square wave while carrying out transmitting power adjustment for the n-1 time;
When | Δ V aD| when-a>0, D n=D n-1-k* Δ V aD, k is adjustment factor.
The beneficial effect of technical scheme provided by the invention is: (1) voltage feedback circuit is simple, and circuit energy consumption is low; (2) feedback voltage regulate algorithm simple, computational speed soon, easily realize; (3), when vivo and vitro coil distance changes, can automatically adjust transmitting power assurance vivo implantation type medical treatment device and normally work; (4) increase Voltage Feedback when radio energy-transmitting, energy emission degree can need to provide energy according to receiving terminal load, is conducive to put forward high-octane effective rate of utilization, extends the useful life of system battery.
Accompanying drawing explanation
Fig. 1 is the structural representation of the wireless and passive implantable medical device based on Voltage Feedback;
Fig. 2 is the circuit theory diagrams of power control unit;
Fig. 3 is the schematic diagram of power amplification circuit;
Fig. 4 is the flow chart of the control method of the wireless and passive implantable medical device based on Voltage Feedback.
In accompanying drawing, being listed as follows of each parts:
A: external controller; B: vivo implantation type medical treatment device;
C: voltage feedback circuit 1: rechargeable battery;
2: charge management module; 3: the first wireless communication modules;
4: first microprocessor; 5: Keysheet module;
6: power control unit; 7: drive circuit;
8: power amplification circuit; 9: show and voice module;
10:PWM generator; 11:BUCK circuit;
12: current rectifying and wave filtering circuit; 13: voltage stabilizing circuit;
14: the second wireless communication modules; 15: medical actuator;
L1: the first coil; C1: the first electric capacity;
L2: the second coil; C2: the second electric capacity.
Embodiment
For making the object, technical solutions and advantages of the present invention clearer, below in conjunction with accompanying drawing, embodiment of the present invention is described further in detail.
In order to solve the low problem of capacity usage ratio in the power supply of wireless and passive implantable medical device, the embodiment of the present invention provides a kind of wireless and passive implantable medical device and control method thereof based on Voltage Feedback, described below:
Referring to Fig. 1, should comprise by the wireless and passive implantable medical device based on Voltage Feedback: external controller A and vivo implantation type medical treatment device B two parts.External controller A is directly for vivo implantation type medical treatment device B provides energy, vivo implantation type medical treatment device B measures for body intrinsic parameter or output signal specific reaches the object for the treatment of certain disease, as brain pacemaker output stimulus signal treatment Parkinson's, cardiac pacemaker output stimulation maintains heart and normally beats.
External controller A comprises: rechargeable battery 1, charge management module 2, the first wireless communication module 3, first microprocessor 4, Keysheet module 5, power control unit 6, drive circuit 7, power amplification circuit 8, demonstration and voice module 9, the first coil L1 and the first capacitor C 1, and power control unit 6 comprises PWM generator 10 and BUCK circuit 11;
Rechargeable battery 1 powers to the first wireless communication module 3, first microprocessor 4, power control unit 6, drive circuit 7, power amplification circuit 8, demonstration and voice module 9, Keysheet module 5, in the time that the electric weight of rechargeable battery 1 exhausts, monitor that by charge management module 2 external power adapter is that rechargeable battery 1 charges, and at any time the electric weight situation of rechargeable battery 1 is fed back to first microprocessor 4, control display module by first microprocessor 4, show battery electric quantity.
The first wireless communication module 3, for communicating by letter with vivo implantation type medical treatment device B, can adopt the module such as nRF24L01 and CC1101.
As shown in Figure 2, power control unit 6 comprises in PWM generator 10 and BUCK circuit 11(Fig. 2 shown in dotted line frame), BUCK circuit 11 output voltage V s are that power amplification circuit 8 is powered, Vs=D*V, D is that PWM generator 10 is exported duty cycle square wave, and V is cell voltage.First microprocessor 4 regulates PWM generator 10 to export the Duty ratio control BUCK circuit 11 output voltage sizes of square wave according to the reception electric weight situation of vivo implantation type medical treatment device B, thereby regulation and control transmitting power is constant to maintain receiving terminal received energy.
As shown in Figure 3, power amplification circuit 8 is made up of four N channel field-effect pipes, and power amplification circuit 8 connects into full-bridge topologies by four N channel field-effect pipes, and power amplification circuit 8 inputs are connected with drive circuit 7 outputs.Drive circuit 7 drives chip or two half-bridge driven chips to form by a full-bridge, and drive circuit 7 input control signals are the full symmetric square wave that first microprocessor 4 is exported.Signal S1, S2 are exported by drive circuit 7, can be directly used in the switch of N channel field-effect pipe in power ratio control amplifying circuit 8.As seen from Figure 3, it is conducting that any time only has M1, M4 or M2, M3, obtains at G1, G2 end the ac square wave that amplitude is Vs.Wherein, drive circuit 7 can be made up of HIP4081 or TPS2836.
The first coil L1 and the first capacitor C 1 resonant circuit in series, utilize resonance to increase transmitting power, is vivo implantation type medical treatment device B energy supply.
As seen from the above, in external controller A, can realize the control to transmitting power by the duty ratio that regulates PWM generator 10 to export square wave.
Show and be connected with the first microcontroller 4 with voice module 9, Keysheet module 5, in order to good user interface to be provided.
Vivo implantation type medical treatment device B comprises: the second coil L2, the second capacitor C 2, current rectifying and wave filtering circuit 12, voltage feedback circuit C, voltage stabilizing circuit 13, the second wireless communication module 14 and medical actuator 15.
The second coil L2 and the second capacitor C 2 formation in parallel resonant circuit, receive the electromagnetic energy that external the first coil L1 transmits.
Current rectifying and wave filtering circuit 12 is connected with the second coil L2, the second capacitor C 2 resonant circuit forming in parallel, and ac electric is converted to direct current, and steady direct voltage V0 is exported in filtering.
Voltage stabilizing circuit 13 is V1 by 0 voltage stabilizing of the output voltage V of current rectifying and wave filtering circuit 12, powers for medical actuator 15 and the second wireless communication module 14, completes that corresponding human parameters is measured or stimulus signal output, and useful information is fed back to external controller A.
Voltage feedback circuit C is connected to after current rectifying and wave filtering circuit 12 in parallel with medical actuator 15, and voltage feedback circuit C is made up of the resistance of two series connection, draws the sampling end of tap as ADC in the middle of two resistance.
In sum, wireless and passive implantable medical device that should be based on Voltage Feedback by external controller A directly for vivo implantation type medical treatment device B provides energy, by increasing Voltage Feedback, energy emission degree can need to provide energy according to receiving terminal load, be conducive to put forward high-octane effective rate of utilization, extend the useful life of system battery.
Referring to Fig. 4, the control method of being somebody's turn to do the wireless and passive implantable medical device based on Voltage Feedback comprises the steps:
First determine the second coil L2 position alignment in external the first coil L1 and body, then open the power supply of external controller A.When the second coil L2 receives after the electromagnetic energy on the first coil L1, through current rectifying and wave filtering circuit 12 output dc voltage V0, after power for medical actuator 15 through voltage stabilizing circuit 13 output voltage V 1.In the time that energy supply is sufficient, on medical actuator 15, there is information exchange to cross the second wireless communication module 14 and feed back to external controller A, inform normal work.First microprocessor 4 receives electric weight situation according to vivo implantation type medical treatment device B and regulates PWM generator 10 to export the Duty ratio control BUCK circuit 11 output voltage sizes of square wave, realize the regulation and control to transmitting power by controlling transmitted waveform amplitude in the first coil L1, constant to maintain receiving terminal received energy, the regulating step of concrete duty ratio is as follows:
101: the sampling end that is first voltage feedback circuit C is set an optimal voltage V aDP;
In actual applications, implantable medical device is installed and used first, as external the first coil L1, when in body, between the second coil L2, distance is determined, BUCK circuit 11 in external controller A can provide a voltage range that is enough to maintain the 15 normal work of implantable medical actuator, now V aDthe minimum sample voltage value of (be the sampling end of voltage feedback circuit C sample the voltage obtaining) is V aDP.
102: obtain voltage difference Δ V aD=V aD-V aDP;
V aD=R2/ (R1+R2) * V0, wherein, V0 is the direct voltage that current rectifying and wave filtering circuit 12 is exported, R1, R2 should meet in the time selecting: R1+R2>10Ri(Ri is late-class circuit input resistance); R1, R2 resistance reasonable mixture ratio, guarantee V aD<V1, V1 is the output voltage of voltage stabilizing circuit 13.
103: the duty ratio of PWM generator 10 being exported to square wave according to voltage difference and preset range is controlled.
Consider entire system operating efficiency, acquiescence Δ V aDin the time of [a, a] range changing, transmitting power is not adjusted, wherein a is constant, can set according to side circuit.For example, in certain implantable medical device, R1:R2=5:1, voltage stabilizing circuit 13 output voltages are 3V, consider entire system operating efficiency, can allow Δ V aDfluctuation within the scope of [0.2,0.2] V.
When | Δ V aD|-a<0 or | Δ V aD| when-a=0, D n=D n-1, Dn is the duty ratio that while carrying out transmitting power adjustment for the n time, PWM generator 10 is exported square wave, D n-1it is the duty ratio that while carrying out transmitting power adjustment for the n-1 time, PWM generator 10 is exported square wave.
When | Δ V aD| when-a>0, D n=D n-1-k* Δ V aD, k is adjustment factor, can arrange according to side circuit Rational Parameters, has both avoided value too large, power adjustments amplitude is large, damages device, again can not be too little, and affect efficiency.
In sum, the embodiment of the present invention provides a kind of control method of the wireless and passive implantable medical device based on Voltage Feedback, this control method is by setting up a simple voltage sampling circuit at energy receiving terminal, feedback receiving-end voltage signal, thereby the transmitting power that regulates transmitting terminal by adjusting the Duty ratio control BUCK circuit output voltage size of PWM generator output square wave, improves capacity usage ratio.
It will be appreciated by those skilled in the art that accompanying drawing is the schematic diagram of a preferred embodiment, the invention described above embodiment sequence number, just to describing, does not represent the quality of embodiment.
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.

Claims (4)

1. the wireless and passive implantable medical device based on Voltage Feedback, comprise: external controller and vivo implantation type medical treatment device, it is characterized in that, described external controller comprises: first microprocessor, PWM generator and BUCK circuit, described vivo implantation type medical treatment device comprises: voltage feedback circuit, described voltage feedback circuit is connected to current rectifying and wave filtering circuit afterwards and is in parallel with medical actuator
Described voltage feedback circuit is made up of the resistance of two series connection, in the middle of two resistance, draws the sampling end of tap as ADC, and the sampled voltage of described medical actuator is fed back to described first microprocessor by described voltage feedback circuit; Described first microprocessor regulates the duty ratio of described PWM generator output square wave according to described sampled voltage, to control described BUCK circuit output voltage size.
2. a kind of wireless and passive implantable medical device based on Voltage Feedback according to claim 1, is characterized in that, described wireless and passive implantable medical device also comprises: rechargeable battery and charge management module,
Described charge management module is for Charge Management and the electric weight situation of described rechargeable battery is fed back to described first microprocessor, and described first microprocessor control display module is realized the electric weight of described rechargeable battery is shown.
3. a kind of wireless and passive implantable medical device based on Voltage Feedback according to claim 1, is characterized in that, described wireless and passive implantable medical device also comprises: power amplification circuit and drive circuit,
Described power amplification circuit connects into full-bridge topologies by four N channel field-effect pipes, described power amplification circuit input is connected with described drive circuit output, described drive circuit drives chip or two half-bridge driven chips to form by a full-bridge, and described drive circuit input control signal is the full symmetric square wave of described first microprocessor output.
4. for a control method for the wireless and passive implantable medical device described in the arbitrary claim of claim 1-3, it is characterized in that, described control method comprises the following steps:
(1) the optimal voltage V of setting voltage feedback circuit sampling end aDP;
(2) obtain voltage difference Δ V aD=V aD-V aDP;
Wherein, V aD=R2/ (R1+R2) * V0, V0 is the direct voltage of current rectifying and wave filtering circuit output; R1, R2 are the voltage of series resistance, and R1+R2>10Ri, and R1, R2 resistance reasonable mixture ratio, make V aD<V1, Ri is late-class circuit input resistance; V1 is the output voltage of voltage stabilizing circuit; (3) according to described voltage difference and preset range [a, a], the duty ratio of PWM generator output square wave is controlled;
When | Δ V aD|-a<0 or | Δ V aD| when-a=0, D n=D n-1, Dn is the duty ratio of PWM generator output square wave while carrying out transmitting power adjustment for the n time, D n-1it is the duty ratio of PWM generator output square wave while carrying out transmitting power adjustment for the n-1 time;
When | Δ V aD| when-a>0, D n=D n-1-k* Δ V aD, k is adjustment factor.
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105186714A (en) * 2015-09-10 2015-12-23 胡江浩 Low-power wireless charging circuit topological structure
CN109245257A (en) * 2018-10-31 2019-01-18 中天华信(天津)智能科技发展有限公司 A kind of wireless charging system and charge power adjusting method
CN117873274A (en) * 2024-03-13 2024-04-12 合源医疗器械(上海)有限公司 Output power control method and device, external device and implant management system

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Publication number Priority date Publication date Assignee Title
US20030085684A1 (en) * 2001-11-07 2003-05-08 Quallion Llc Implantable medical power module
CN102130514A (en) * 2011-03-30 2011-07-20 上海北京大学微电子研究院 Wireless power supply device of diagnosis and treatment system
CN102832722A (en) * 2012-08-31 2012-12-19 华南理工大学 Implanted self-adaptive wireless source transmission method and system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030085684A1 (en) * 2001-11-07 2003-05-08 Quallion Llc Implantable medical power module
CN102130514A (en) * 2011-03-30 2011-07-20 上海北京大学微电子研究院 Wireless power supply device of diagnosis and treatment system
CN102832722A (en) * 2012-08-31 2012-12-19 华南理工大学 Implanted self-adaptive wireless source transmission method and system

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105186714A (en) * 2015-09-10 2015-12-23 胡江浩 Low-power wireless charging circuit topological structure
CN109245257A (en) * 2018-10-31 2019-01-18 中天华信(天津)智能科技发展有限公司 A kind of wireless charging system and charge power adjusting method
CN109245257B (en) * 2018-10-31 2024-04-19 智核奇点科技(深圳)有限公司 Wireless charging system and charging power adjusting method
CN117873274A (en) * 2024-03-13 2024-04-12 合源医疗器械(上海)有限公司 Output power control method and device, external device and implant management system
CN117873274B (en) * 2024-03-13 2024-05-31 合源医疗器械(上海)有限公司 Output power control method and device, external device and implant management system

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