CN103768142A - Fever-reducing patch and preparation method thereof - Google Patents
Fever-reducing patch and preparation method thereof Download PDFInfo
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- CN103768142A CN103768142A CN201210402682.XA CN201210402682A CN103768142A CN 103768142 A CN103768142 A CN 103768142A CN 201210402682 A CN201210402682 A CN 201210402682A CN 103768142 A CN103768142 A CN 103768142A
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- Prior art keywords
- fever
- layer
- reducing patch
- defervescent
- picking
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a fever-reducing patch and a preparation method thereof. The fever-reducing patch consists of a backing layer, a pasting layer and a gel medicine layer. The fever-reducing patch is characterized that the fever-reducing patch is a thermoplastic polymer adhesive, and is composed of a thermoplastic elastomer with the melting point of 50-250 DEG C, a tackifier, a plasticizer and the like. The fever-reducing patch is convenient and rapid to use and rapid in absorption, helps to reduce requirements on dosing frequency and dosage, and helps to mitigate side effects of oral medicines and injection medicines on gastrointestinal tracts and the like.
Description
Technical field
Patent of the present invention relates to a kind of patch, the simple and easy Defervescent picking that particularly a kind of energy absorbs rapidly by skin.
Background technology
In the middle of life, fever is unavoidable, market drug for abating fever is also a feast for the eyes, but traditional febrifuge route of administration is without parenteral, intramuscular injection and intravenous administration, has certain traumatic, systemic administration side effect is large and onset is slow, and drug effect is subject to the factor impacts such as medicine number of times, dosage.
summary of the invention
The object of the invention is to make up above-mentioned deficiency, overcome drug for abating fever clinically and use central drawback, this technological invention provides a kind of Simple Skin patch, formed by backing layer, adhered layer and gel medicine layer three part, reach the dual function of bringing down a fever by antipyretic and high-molecular gel: (1) Drug therapy: gel layer is by the transdermal enhancing effect of hydration and Percutaneous absorption enhancer, make effective ingredient with which enter blood circulation through skin, reach comprehensive, lasting effect.(2) Physical temperature-lowering: hydrophilic gel has good power conversion function, is absorbed heat and is taken away a large amount of hot temperatures of body local by vaporization, and positive energy exchange, brings down a fever rapidly, protection brain cell.
Technical scheme of the present invention is: a kind of Defervescent picking, is made up of backing layer, adhered layer and medicine layer three parts.After each medicine is weighed according to percentage by weight, be dissolved in polymer matrix, on adhesion and adhered layer, add non-woven fabrics backing layer.
Compared with existing product, the advantage of this invention:
(1) bring down a fever by acetaminophen and polymer drug and the dual-use function of physics heat radiation, the effect of bringing down a fever is better;
(2) make medicine play antipyretic effect by being affixed on skin surface, reduce drug side effect;
(3) local drug concentration is higher than the blood drug level of oral or intravenous administration;
(4) patient's medication voluntarily, only need throw off patch gets final product interruption of the administration, and medication is convenient.
The specific embodiment
Adhered layer is a kind of thermoplastic polymer adhesive, and its composition comprises that fusing point is the thermoplastic elastomer (TPE) of 50-250 ℃ and viscosifier, plasticizer etc.
Medicine is weighed as follows according to percentage by weight: acetaminophen 2～11%, Herba Menthae 1～15%, ethanol 1～20%, polymer substance 5～15%.
In addition, can add as required glycerol 1～10%, Borneolum Syntheticum 1～15%, Flos Lonicerae extract 0.5～1%, water 2～20%.
Claims (4)
1. the present invention discloses a kind of Defervescent picking, it is characterized in that said Defervescent picking is made up of backing layer, adhered layer and gel medicine layer three part.
2. the main medicine addressed is acetaminophen 2～11%, Herba Menthae 1～15%, ethanol 1～20%, separately has high-molecular gel substrate.
3. Defervescent picking according to claim 1, is characterized in that, said adhered layer is a kind of thermoplastic polymer adhesive, and its composition comprises that fusing point is the thermoplastic elastomer (TPE) of 50-250 ℃ and viscosifier, plasticizer etc.
4. Defervescent picking according to claim 2, is characterized in that, the medicine of addressing also has polymer substance 5～15%, glycerol 1～10%, Borneolum Syntheticum 1～15%, Flos Lonicerae extract 0.5～1% and water 2～20%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210402682.XA CN103768142A (en) | 2012-10-22 | 2012-10-22 | Fever-reducing patch and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210402682.XA CN103768142A (en) | 2012-10-22 | 2012-10-22 | Fever-reducing patch and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103768142A true CN103768142A (en) | 2014-05-07 |
Family
ID=50561202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210402682.XA Pending CN103768142A (en) | 2012-10-22 | 2012-10-22 | Fever-reducing patch and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103768142A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168208A (en) * | 2015-06-30 | 2015-12-23 | 武汉烺祺生物科技有限公司 | Externally used drug for abating fever and preventing sunstroke |
-
2012
- 2012-10-22 CN CN201210402682.XA patent/CN103768142A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168208A (en) * | 2015-06-30 | 2015-12-23 | 武汉烺祺生物科技有限公司 | Externally used drug for abating fever and preventing sunstroke |
| CN105168208B (en) * | 2015-06-30 | 2019-01-01 | 武汉烺祺生物科技有限公司 | A kind of external drug brought down a fever and prevented heatstroke and lower the temperature of bringing down a fever |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140507 |