CN103751869B - For liquid conveying system and the operational approach thereof of peritoneal dialysis - Google Patents

For liquid conveying system and the operational approach thereof of peritoneal dialysis Download PDF

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Publication number
CN103751869B
CN103751869B CN201310727308.1A CN201310727308A CN103751869B CN 103751869 B CN103751869 B CN 103751869B CN 201310727308 A CN201310727308 A CN 201310727308A CN 103751869 B CN103751869 B CN 103751869B
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passage
filling
row
liquid
waste discharge
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CN103751869A (en
Inventor
王洪利
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Shenzhen Zhili Medical Technology Co ltd
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BEIJING SUNNY MEDICAL TECHNOLOGY Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/28Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
    • A61M1/282Operational modes
    • A61M1/284Continuous flow peritoneal dialysis [CFPD]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/28Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/28Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
    • A61M1/287Dialysates therefor

Abstract

The invention discloses the liquid conveying system for peritoneal dialysis and operational approach thereof, wherein, passage is arranged in the filling that liquid conveying system for peritoneal dialysis comprises for being connected with human abdominal cavity, for the liquid feeding channel that the waste discharge passage being carried out from the liquid that intraperitoneal is discharged by the row's of filling passage discharging is connected with the liquid bag be used for hold dialysis solution, described filling row passage, waste discharge passage and liquid feeding channel are connected correspondingly with the liquid stream port of three non-uniform Distribution of three-way valve and connection in realizing passage at least between two between each two respective channel under a certain state, described filling row passage is also provided with the row's of filling pump, described filling row pump is two-way pump, to control the row of filling passage liquid stream direction.The technical problem that the present invention solves is to overcome the shortcoming of high, the complicated operation of required precision of existing peritoneal dialysis machine transfusion system complex structure, processing, provide structure simple, be easy to processing and the liquid conveying system for peritoneal dialysis of simple operation and operational approach thereof.

Description

For liquid conveying system and the operational approach thereof of peritoneal dialysis
Technical field
The present invention relates to medical instruments field.Be specially the liquid conveying system and operational approach thereof that are applicable to peritoneal dialysis.
Background technology
Peritoneal dialysis (PeritonealDialysis, english abbreviation PD) is a kind of one of more effective blood purification mode at present, carries out the surrogate therapeutic of renal function after being applicable to human body injury of kidney.Its cardinal principle is the peritoneal cavity aseptic, the apyrogenic dialysis solution prepared being poured into patient through conduit, the semipermeable membrane characteristic of peritoneum is utilized to carry out disperse, infiltration, exchange, and constantly changed by abdominal dialysis liquid, reach purged body intracellular metabolite refuse or toxin, and correct the object of water, electrolyte, acid base imbalance.The operation principle of peritoneal dialysis treatment is to intraperitoneal perfusion dialysis solution and after retaining a period of time, gets rid of external by the waste liquid after exchanging, and is namely made up of perfusion, stop, discharge three important steps.Peritoneal dialysis mainly contain two types, continuous Ambulatory peritoneal dialysis (english abbreviation CAPD) and automatization's peritoneal dialysis (english abbreviation APD).CAPD is manually-operated, and every day is changed 3-5 time, and each 2000ml, APD realize by peritoneal dialysis machine usually.Peritoneal dialysis machine or be called cycler (Cycler), usual patient stays at home and carries out every night, multiple liquid bag perfusion, stop, the whole loop control process of discharging completes automatically by machine.APD is the peritoneal dialysis technology of a develop rapidly in recent years, and it not only can help the technical problem solving patient's long-term treatment, and the patient of many renal failures can also be helped to reintegrate into society, and is society, family's creation of value.The technological core of APD is liquid supplying way, particularly patent CN1829545B, 200680012708.2 representative for current APD liquid supplying way.But in its fluid administration system design, all have employed numerous special valves or air door carries out logical combination, control with the break-make realizing each pipeline, its pipeline structure is caused to design complicated, requirement on machining accuracy is high, and thus cost is very high, and its operation more complicated.
Summary of the invention
The technical problem that the present invention solves is to overcome the shortcoming of high, the complicated operation of required precision of existing peritoneal dialysis transfusion system complex structure, processing, provide a kind of structure simple, be easy to processing and the liquid conveying system for peritoneal dialysis of simple operation.
Liquid conveying system for peritoneal dialysis of the present invention, passage is arranged in the filling comprised for being connected with human abdominal cavity, for the liquid feeding channel that the waste discharge passage being carried out from the liquid that intraperitoneal is discharged by the row's of filling passage discharging is connected with the liquid bag be used for hold dialysis solution, described filling row passage, waste discharge passage and liquid feeding channel are connected correspondingly with three liquid stream ports of three-way valve and connection in realizing passage at least between two between each two respective channel under a certain state, described filling row passage is also provided with the row's of filling pump, described filling row pump is two-way pump, to control the row of filling passage liquid stream direction.
As preferably, between described at least two respective channel the connection of a certain state comprise fill with row passage be communicated with between waste discharge passage, the row's of filling passage is communicated with between liquid feeding channel, be communicated with between liquid feeding channel with waste discharge passage, or passage and being communicated with between waste discharge passage and liquid feeding channel three passages are arranged in filling.
As preferably, described three-way valve comprises valve body and spool, described spool has at least three and communicates with each other and through liquid flowing channel, and described valve body is provided with three with two liquid flowing channels each in the liquid flowing channel between two of described liquid flowing channel at the corresponding described liquid stream port be communicated with of different conditions.
As preferably, the valve body of described three-way valve is the cylindric valve body with inner core, the spool of described three-way valve is the inwall being positioned at described valve body and being close to described valve body, relative to the cylindrical spool that described valve body rotates, described spool has three and communicates with each other and through described liquid flowing channel, three described liquid flowing channels form "T"-shaped or " Y " shape in the projection of horizontal plane, and the length of T-shaped or Y shape two arm portions is equal with the length of vertical section, described valve body is provided with three with two liquid flowing channels each in the liquid flowing channel between two of described liquid flowing channel at the corresponding described liquid stream port be communicated with of different conditions.
As preferably, when three described liquid flowing channels form " Y " in the projection of horizontal plane, angle between the projection of wherein two liquid flowing channels is 60 °, and the angle between the projection of the projection of another liquid flowing channel and these two liquid flowing channels is 150 °.
As preferably, described spool is connected with the driving device driving described Spool rotating, and described driving device is electrohydraulic valve actuator machine or mechanical energy rotary apparatus.
As preferably, described filling row pump is peristaltic pump or membrane pump.
As preferably, the described row's of filling passage is provided with at least one for detecting the first via pressure transducer of the pressure in the described row of filling passage, described first via pressure transducer is between abdominal cavity and the row's of filling pump, described liquid feeding channel is provided with at least one for detecting the second road pressure transducer of the pressure in described liquid feeding channel, and described waste discharge passage is provided with at least one for detecting the 3rd road pressure transducer of the pressure in described waste discharge passage.
As preferably, described first via pressure transducer and described filling are arranged between passage, between described second road pressure transducer and described liquid feeding channel and between described 3rd road pressure transducer and described waste discharge passage and are equipped with barrier film device.
As preferably, described filling row passage, liquid feeding channel and/or waste discharge passage are also provided with at least one for detecting the temperature sensor of the temperature of dialysis solution, and/or described filling is arranged passage, liquid feeding channel and/or is provided with barrier film device between waste discharge passage and the temperature sensor being located at this passage.
As preferably, described filling row passage, waste discharge passage and/or liquid feeding channel are provided with at least one flow transducer and/or weight sensor and/or optical pickocff, are provided with barrier film device between each passage and the flow transducer be located on this passage and/or weight sensor and/or optical pickocff.
As preferably, described barrier film device comprises housing and is positioned at the barrier film of described housing, and the lumen segmentation that described housing surrounds becomes by described barrier film arranges the first chamber that passage or liquid feeding channel or waste discharge passage are connected and the second chamber be connected with described temperature sensor or described pressure transducer with filling.
As preferably, described barrier film is by be discharged into without the granule come off or shot in fluid and the good material of biocompatibility is made, as silicone, polyurethane, Biopure tM, Kraton tM, Pebax tMor Santoprene tMin any one material make.
As preferably, the liquid conveying system of described peritoneal dialysis also comprises control device, and described control device and described first via pressure transducer, the second road pressure transducer, the 3rd road pressure transducer, driving device and filling are arranged pump and be connected with according to the relation accessory drive between the pressure of the row's of filling passage, liquid feeding channel and waste discharge passage or each channel pressure and/or the row's of filling pump.
As preferably, described control device is also connected with according to the temperature accessory drive of dialysis solution and/or the row's of filling pump with described temperature sensor.
As preferably, the flow transducer of described control device and the described row's of filling passage and waste discharge channel setting and/or weight sensor and/or optical pickocff are connected.
As preferably, the described row of filling passage, liquid feeding channel and waste discharge passage are made up of the tube for transfusion be tightly connected with described three-way valve.
As preferably, described filling row passage, liquid feeding channel, waste discharge passage and three-way valve are integrated in a replaceable cartridge.
The present invention also provides a kind of as above for the operational approach of the liquid conveying system of peritoneal dialysis, comprises following operator scheme:
Fill-up mode: be communicated with the row's of filling passage and human abdominal cavity, regulating three-way valve makes filling row passage communicate with liquid feeding channel, between waste discharge passage and liquid feeding channel and waste discharge passage and fill with and arrange between passage and cut off, the rotation direction of row's pump is filled with in adjustment, the rotation direction of filling row pump makes liquid enter filling from dialyzate bag by liquid feeding channel and three-way valve under the effect of the row's of filling pump and arranges passage and the abdominal cavity flowing to human body, thus realizes dialysis solution to be injected in human abdominal cavity;
Waste discharge pattern: regulating three-way valve makes filling arrange passage and waste discharge channel connection, liquid feeding channel and filling are arranged between passage and between liquid feeding channel and waste discharge passage and are all cut off, make the rotation direction of filling row pump contrary with the operative orientation under fill-up mode, Intraabdominal liquid is sequentially passed through under the effect of the row's of filling pump, and passage is arranged in filling, three-way valve enters waste discharge passage and flows out, thus realizes Intraabdominal waste liquid to excrete.
As preferably, also there is the pattern of pipeline being carried out to pre-flush before fill-up mode, be specially: regulating three-way valve makes liquid feeding channel arrange passage be communicated with mutually with waste discharge passage with filling, dialysis solution flows into the row's of filling passage and waste discharge passage discharging from dialyzate bag respectively through liquid feeding channel, realizes the pre-flush to pipeline.
The present invention also provides another for the operational approach of the liquid conveying system of peritoneal dialysis, comprises following operator scheme:
Fill-up mode: be communicated with the row's of filling passage and human abdominal cavity, regulating three-way valve makes filling row passage communicate with liquid feeding channel, between waste discharge passage and liquid feeding channel and waste discharge passage and fill with and arrange between passage and cut off, the rotation direction of row's pump is filled with in adjustment, the rotation direction of filling row pump makes dialysis solution enter filling from dialyzate bag by liquid feeding channel and three-way valve under the effect of the row's of filling pump and arranges passage and the abdominal cavity flowing to human body, thus realizes dialysis solution to be injected in human abdominal cavity;
Regulating three-way valve makes filling arrange passage and waste discharge channel connection, liquid feeding channel and filling are arranged between passage and between liquid feeding channel and waste discharge passage and are all cut off, make the rotation direction of filling row pump contrary with the operative orientation under fill-up mode, Intraabdominal liquid is sequentially passed through under the effect of the row's of filling pump, and passage is arranged in filling, three-way valve enters waste discharge passage and flows out, thus realizes Intraabdominal waste liquid to excrete;
In fill-up mode, detect the pressure of liquid feeding channel by first via pressure transducer and/or detected the row's of filling channel pressure by the second road pressure transducer and fed back to control device, described control device controls the action of three-way valve and the row's of filling pump.
As preferably, when the pressure of liquid feeding channel and/or the row's of filling channel pressure numerical value reach the first setting value, the liquid conveying system that control device controls to be used for peritoneal dialysis enters waste discharge pattern.
As preferably, control device calculates the pressure of liquid feeding channel and the pressure difference therebetween of the row's of filling passage, and when difference reaches the second setting value, the liquid conveying system that control device controls to be used for peritoneal dialysis enters waste discharge pattern.
As preferably, by temperature sensor detect liquid feeding channel or fill with row passage in dialysis solution temperature and by temperature value transmission control device, when temperature value exceeds set point, control device regulating three-way valve makes liquid feeding channel and waste discharge channel connection make filling arrange between passage with liquid feeding channel simultaneously and the row's of filling passage is not all communicated with between waste discharge passage, thus dialysis solution is discharged through liquid feeding channel, three-way valve and waste discharge passage; Or when temperature value exceeds set point, the liquid conveying system that control device controls to be used for peritoneal dialysis enters waste discharge pattern.
As preferably, control device according to the data that the flow transducer on the row's of filling passage and/or weight sensor and/or optical pickocff transmit calculate each perfusion institute pour into the dialysis solution in human abdominal cavity amount and repeatedly perfusion institute pour into the dialysis solution cumulative amount in human abdominal cavity, control device can calculate the cumulative amount of the amount of the waste liquid of each waste discharge discharge and the waste liquid of repeatedly waste discharge discharge according to the data that the flow transducer on waste discharge passage and/or weight sensor and/or optical pickocff transmit.
Liquid conveying system for peritoneal dialysis of the present invention and operational approach thereof compared with prior art, have following beneficial effect:
1, the liquid conveying system for peritoneal dialysis of the present invention can complete by means of only three-way valve and two-way filling row pump and carry out pre-flush to passage, pours into dialysis solution to abdominal cavity of patients, from several operations such as the outside drained liquid of abdominal cavity of patients, the incompatible technology realizing the switching of multiple operation of logical groups that the valve numerous with existing dependence carries out break-make is compared, enormously simplify structure and operating procedure, reduce the requirement to machining accuracy, thus its cost is reduced, also make reliably easy and simple to handle simultaneously.
2, simple, the reliable operation of the structure of its three-way valve, and its spool is driven by electrohydraulic valve actuator machine, can make the spinning movement of spool more accurately, reliable.
3, its row's of filling pump adopts membrane pump or peristaltic pump, prevents the inwall of pump from contacting with dialysis solution and polluting dialysis solution.
4, its temperature sensor and pressure transducer are all by barrier film device and expanding channels, can prevent temperature sensor from directly contacting with dialysis solution with pressure transducer and polluting dialysis solution.
5, its control device can according to the temperature control valve drive motors of the relation between the row's of filling pressure of passage, liquid feeding channel and waste discharge passage or each channel pressure or temperature sensor and the row's of filling pump, three-way valve is made automatically to adjust to the position of needs, make the action of three-way valve timely and reliable, and control start and stop and the direction of rotation of the row's of filling pump, avoid operator and postpone to operate the danger produced.
Accompanying drawing explanation
Fig. 1 is the structural representation of the liquid conveying system embodiment for peritoneal dialysis of the present invention.
Fig. 2 is three position views of the three-way valve of the liquid conveying system for peritoneal dialysis of the present invention.
Fig. 3 is the schematic diagram of the liquid conveying system for peritoneal dialysis of the present invention when carrying out pre-flush channel operation.
Fig. 4 is the schematic diagram that the liquid conveying system for peritoneal dialysis of the present invention carries out when pouring into dialysis solution operation to abdominal cavity of patients.
Fig. 5 be the liquid conveying system for peritoneal dialysis of the present invention carry out from the outside drained liquid of abdominal cavity of patients operation time schematic diagram.
Fig. 6 is the schematic diagram that the liquid conveying system for peritoneal dialysis of the present invention stopping fills with when arranging.
Fig. 7 is the structural representation of the three-way valve of the liquid conveying system for peritoneal dialysis of the present invention, and wherein left figure is the cross sectional representation of three-way valve, and right figure is the longitudinal section of three-way valve and the structural representation of electrohydraulic valve actuator machine.
Fig. 8 is the schematic diagram of the peristaltic pump of the liquid conveying system for peritoneal dialysis of the present invention.
Fig. 9 is the schematic diagram of the barrier film device of the liquid conveying system for peritoneal dialysis of the present invention.
Figure 10 is the cartridge type schematic diagram of the liquid conveying system for peritoneal dialysis of the present invention.
Reference numeral
1-fills with row's passage, 2-liquid feeding channel, 3-waste discharge passage, 4-three-way valve, 6-fills with row's pump, 7-liquid bag, 10-valve body, 11-spool, 11a-spool rear end, 12-liquid flowing channel, 13-liquid stream port, 14-electrohydraulic valve actuator machine, 15-pump head, 16-pump drive motors, 17-roller, 18-bearing, 19-temperature sensor, 20-barrier film device, 21-first via pressure transducer, 22-second road pressure transducer, 23-the 3rd road pressure transducer, 24-housing, 25-barrier film, 26-first chamber, 27-second chamber, 28-pump line, 29-first joint, 30-second joint, 31-control device.
Detailed description of the invention
The structural representation of Fig. 1 liquid conveying system embodiment for peritoneal dialysis of the present invention.As shown in Figure 1, liquid conveying system for peritoneal dialysis of the present invention, comprise the row of filling passage 1, liquid feeding channel 2 and waste discharge passage 3, the row's of filling passage 1 is for being connected with abdominal cavity, liquid feeding channel is used for being connected with the liquid bag holding dialysis solution, and waste discharge passage 3 is discharged for the liquid of being discharged from intraperitoneal by the row's of filling passage.Described filling row passage 1, liquid feeding channel 2 are connected with three liquid stream ports 13 of three-way valve 4 correspondingly with waste discharge passage 3, and the connection of realization at least between two in passage between each two respective channel under a certain state.Described filling row passage 1 is also provided with the row's of filling pump 6, and described filling row pump 6 is two-way pump, to control the row of filling passage liquid stream direction.
In the present invention, " three-way valve 4 " refers to have at least three liquid stream ports 13, and following operation can be realized: three liquid stream ports 13 all communicate with each other, or in three liquid stream ports 13 any two are interconnected, another liquid stream port 13 is closed simultaneously, or three liquid stream ports 13 are not communicated with all mutually.Therefore, three-way valve 4 of the present invention can adopt the valve of various concrete form and structure, as long as realize above function.
In the present invention, between described at least two respective channel the connection of a certain state comprise fill with row passage be communicated with between waste discharge passage, the row's of filling passage is communicated with between liquid feeding channel, be communicated with between liquid feeding channel with waste discharge passage, certainly, the row's of filling passage also can all be communicated with under a certain state with between waste discharge passage and liquid feeding channel three passages.
In the present invention, " two-way pump " refer to can realize inlet be switching to liquid outlet simultaneously liquid outlet be switching to the pump of inlet, that is, the pump that flow direction can be switched in positive and negative both direction can be realized.
In the present invention, as preferred scheme, described three-way valve comprises valve body and spool, described spool has at least three and communicates with each other and through liquid flowing channel, and described valve body is provided with three with two liquid flowing channels each in the liquid flowing channel between two of described liquid flowing channel at the corresponding described liquid stream port be communicated with of different conditions.As further preferred, the valve body of three-way valve 4 is the cylindric valve body 10 with inner core, spool is the inwall being positioned at described valve body 10 and can being close to described valve body 10, relative to the cylindrical spool 11 that described valve body 10 rotates, as shown in Figure 7, described spool 11 has three and communicates with each other and through described liquid flowing channel 12, three liquid flowing channels 12 form "T"-shaped or " Y " shape in the projection of horizontal plane, and the length of T-shaped or Y shape two arm portions is equal with the length of vertical section, in the present embodiment, three liquid flowing channels 12 form "T"-shaped in the projection of horizontal plane, wherein two liquid flowing channels 12 are arranged in same level, another liquid flowing channel 12 is arranged on another horizontal plane.Described valve body 10 is provided with three with two liquid flowing channels each in the liquid flowing channel between two of described liquid flowing channel at the corresponding described liquid stream port 13 be communicated with of different conditions.
In other examples, three liquid flowing channels also can form " Y " shape (not shown) jointly, as, when three described liquid flowing channels form " Y " in the projection of horizontal plane, angle between the projection of wherein two liquid flowing channels is 60 °, angle between the projection of the projection of another liquid flowing channel and these two liquid flowing channels is 150 °, also can be other angles between certain three liquid flowing channels.
Certainly, spool also can arrange more liquid flowing channel, and liquid flowing channel can evenly be arranged, and also can non-homogeneously arrange, as long as can realize several situations communicating or disconnect between above-mentioned said three liquid stream ports.
By above scheme, liquid conveying system for peritoneal dialysis of the present invention at least can realize following operation: pour into dialysis solution to abdominal cavity of patients, from the outside drained liquid of abdominal cavity of patients, in addition, the liquid conveying system for peritoneal dialysis of the present invention also can realize carrying out pre-flush to passage.
Fig. 3 is the schematic diagram of the liquid conveying system for peritoneal dialysis of the present invention when carrying out pre-flush channel operation, as shown in several 1st figure left in Fig. 3 and Fig. 2, when pre-flush is carried out to passage, three liquid flowing channels 12 of three-way valve 4 are relative one by one with three liquid stream ports 13, three-way valve 4 is all communicated with waste discharge passage 3 with liquid feeding channel 2, the row's of filling passage 1, and the now row's of filling pump 6 forward running makes liquid to the left flowing in figure.Dialysis solution enters three-way valve 4 through liquid feeding channel 2 and flows into the row's of filling passage 1 and waste discharge passage 3 by three-way valve 4, and the flow direction of dialysis solution as indicated by the arrows in fig. 3.Dialysis solution can stop pre-flush operating after being full of the row's of filling passage 1 and waste discharge passage 3, and this operation can be driven the air in each passage away and be cleaned passage.
Fig. 4 is the schematic diagram that the liquid conveying system for peritoneal dialysis of the present invention carries out when pouring into dialysis solution operation to abdominal cavity of patients, as shown in several 2nd figure left in Fig. 4 and Fig. 2, when pouring into dialysis solution to abdominal cavity of patients, two liquid flowing channels 12 of three-way valve 4 are aimed at two the liquid stream ports 13 be connected with the row of filling passage 1 with liquid feeding channel 2 respectively and liquid feeding channel 2 are connected by three-way valve 4 with the row of filling passage 1, another liquid flowing channel 12 is closed, the now row's of filling pump 6 forward running makes liquid to the left flowing in figure, that is, the intraperitoneal of human body is flowed into.Dialysis solution enters three-way valve 4 through liquid feeding channel 2 and flows into the row's of filling passage 1 by three-way valve 4, and pump into the intraperitoneal of human body through the row's of filling pump 6, the flow direction of dialysis solution as shown by the arrows in figure 4.
Fig. 5 be the liquid conveying system for peritoneal dialysis of the present invention carry out from the outside drained liquid of abdominal cavity of patients operation time schematic diagram, as shown in several 3rd figure left in Fig. 5 and Fig. 2, two liquid flowing channels 12 of three-way valve 4 are aimed at and are arranged two liquid stream ports 13 that passage 1 is connected with waste discharge passage 3 row's of filling passage 1 is connected by three-way valve 4 with waste discharge passage 3 with filling with respectively, and another liquid flowing channel 12 is closed.The row's of filling pump 6 antiport, makes the liquid stream in abdominal cavity out enter the row's of filling passage 1, and then enters waste discharge passage 3 and discharge, and the flow direction of liquid as shown in Figure 5.
Fig. 6 is the schematic diagram that the liquid conveying system for peritoneal dialysis of the present invention stopping fills with when arranging, as shown in Figure 6, the row's of filling pump 6 is out of service, three liquid flowing channels 12 of three-way valve 4 are all closed, as shown in left several 4th figure in Fig. 2, now the row's of filling passage 1, liquid feeding channel 2 are not communicated with mutually with waste discharge passage 3, can prevent liquid from flowing out.
Liquid conveying system for peritoneal dialysis of the present invention can complete above-mentioned all operations by means of only three-way valve and two-way filling row pump, compare with existing dependence technology, enormously simplify structure, reduce the requirement to machining accuracy, thus its cost is reduced, also make reliably easy and simple to handle simultaneously.
As preferably of the present invention, spool rear end 11a connecting drive device, driving device is applicable to the project into "T"-shaped and spool of " Y " shape of liquid flowing channel at horizontal plane.Driving device is preferably electrohydraulic valve actuator machine 14, as shown in Figure 7, left figure is the cross sectional representation of three-way valve 4, right figure is the longitudinal section of three-way valve 4 and the schematic diagram of electrohydraulic valve actuator machine 14, by operating valve drive motors 14, spool 11 to be rotated to the position needed to carry out corresponding pre-flush, to intraperitoneal perfusion dialysis solution, from abdominal cavity drained liquid or make filling arrange the operation such as stopping.The driving device that certain driving device also can adopt other actuatable valve cores to rotate as, rotary handle, or other mechanisms rotated by mechanical energy.
As preferably of the present invention, described filling row pump 6 is peristaltic pump or membrane pump, make dialysis solution can not with the contact internal walls of pump, prevent from other materials to bring in human body to work the mischief to human body.Wriggling pump structure as shown in Figure 8, left figure is the front view of peristaltic pump, right figure is the assembly structure figure of peristaltic pump, the pump drive motors 16 that peristaltic pump comprises pump head 15, flexible pump line 28 and drives pump head 15 to rotate, and pump head 15 is provided with multiple roller 17 be evenly arranged.Pump head 15 is also provided with pump head bearing 18, and is connected with pump drive motors 16 by bearing 18.
Well-known in this area, the efficiency of peritoneal dialysis is directly related in the intraperitoneal time with iiquid residence, and the discharge stage can limit with regard to its persistent period, and this persistent period is the function of drainage rate.The initial discharge process of usual CAPD is about 200ml/min, and along with patient's intra-abdominal pressure reduces, this drainage rate also decreases, and also just directly affects whole dialysis time.Therefore, in the design of APD, how dynamic adjustments, for the pump speed of the row of filling, seems particularly important to improve dialytic efficiency.
As preferably of the present invention, the present invention gives a solution: be designed to two kinds of contact conditions between pump head 15 and pump line 28: extrusion pump tubulose state and non-extrusion pump tubulose state.Particularly, move up and down by the related pump head 15 of pump head bearing 18 conversion realizing two kinds of states, wherein further comprises pump drive motors 16 and give kinetic energy by the pinion rotation in pump head 15.
When under extrusion pump tubulose state, when pump head 15 rotates, roller 17 extrudes flexible pump line 28, the direction flowing that liquid runs down in flexible pump line 28 is extruded, the flow velocity of row's pump 6 now can be filled with by the requirement setting of anticipation, now, also by adopting high-precision numeric type, each circumfusion amount that flow type peristaltic pump calculates dialysis solution and accumulative groundwater increment.
Under non-extrusion pump tubulose state, pump head 15 pairs of pump lines 28 do not control, ensure to start to rely on Intraabdominal pressure to realize naturally draining of waste liquid in discharge process, and when intra-abdominal pressure reduction can not continue nature excretion, change pump line again into squeezed state, now also carry out by the pressure differential between multiple pressure transducer the speed that dynamic adjustments fills with row's pump 6, the time of discharge process can be shortened on the one hand, ensure the groundwater increment dischargeable capacity of next circulation, to improve dialytic efficiency, also to ensure that drainage rate is the tolerance interval of patient safety on the other hand.After this, also by the effect of the pressure transducer described in description.
Certainly, these are only preferred scheme, other also can be adopted to make liquid and the discontiguous pump of pump, and the operation requirements of perfusion needed for peritoneal dialysis, reservation, discharge process can be met.
As preferably, described filling row passage 1, liquid feeding channel 2 and/or waste discharge passage 3 are also provided with at least one for detecting the temperature sensor 19 of the temperature of dialysis solution.In the present embodiment, described liquid feeding channel 2 and the row's of filling passage 1 are equipped with the temperature sensor 19 of the temperature for detecting dialysis solution.Waste discharge passage 3 can be arranged also can not set temperature sensor.Temperature sensor 19 is more reliable than the temperature of human perception dialysis solution, can detect the temperature of dialysis solution more accurately, more in time, prevents the dialysis solution being unsuitable for body temperature from flowing into human body.Be provided with barrier film device 20 between described temperature sensor and the passage being provided with this temperature sensor, can prevent temperature sensor 19 from contacting with dialysis solution and polluting dialysis solution.Certainly, the row's of filling passage also can set temperature sensor, is also provided with barrier film device between the row's of filling passage and the temperature sensor being located at the row's of filling passage.
Well-known in this area, filling with row pressure power Measurement & Control in peritoneal dialysis process is a very important factor, if the pressure increase of particularly linking on the pipeline of patient exceeds warning restriction, may produce serious injury to patient.As preferably, the described row's of filling passage 1 is provided with at least one for detecting the first via pressure transducer 21 of the pressure in the described row of filling passage 1, described first via pressure transducer 21 is between abdominal cavity and the row's of filling pump 6, described liquid feeding channel 2 is provided with at least one for detecting the second road pressure transducer 22 of the pressure in described liquid feeding channel 2, and described waste discharge passage 3 is provided with at least one for detecting described the 3rd road pressure transducer 23 for the pressure in waste discharge road.Be equipped with barrier film device 20 between described first via pressure transducer 21 and the described row of filling passage 1, between described second road pressure transducer 22 and described liquid feeding channel 2 and between described 3rd road pressure transducer 23 and described waste discharge passage 3, can prevent pressure transducer from directly contacting with liquid.
Described filling row passage 1, waste discharge passage 3 and/or liquid feeding channel 2 are provided with at least one flow transducer and/or weight sensor and/or optical pickocff.That is, the row's of filling passage 1 and waste discharge passage 3 are equipped with a flow transducer and/or weight sensor and/or optical pickocff, and liquid feeding channel 2 can arrange the sensor, also can not arrange.
Described barrier film device 20 comprises housing 24 and is positioned at the barrier film 25 of described housing 24, and as shown in Figure 9, housing can be the cylindricality in the left figure of figure, can also be spherical as in right figure.The lumen segmentation that described housing 24 surrounds becomes by described barrier film 25 arranges the first chamber 26 that passage 1 or liquid feeding channel 2 or waste discharge passage 3 are connected and the second chamber 27 be connected with described temperature sensor 19 or pressure transducer with filling.First chamber of barrier film device has for having the second joint 30 for being connected with temperature sensor or pressure transducer with channel attached first joint 29, second chamber.Temperature sensor 19 is by detecting the temperature of the barrier film 25 directly contacted with dialysis solution to determine the temperature of dialysis solution.Pressure transducer determines the pressure of liquid by the air pressure in the second chamber 27 of detecting the deformation of barrier film 25 or barrier film 25 deformation and causing or pressure change.
As preferably, barrier film 25 is biocompatible, and such as, by welding, clamping, gluing, laser or hot melt, barrier film 25 is easily sealed in the liquid conveying system for peritoneal dialysis.In addition, barrier film 25 should by be discharged into without the granule that come off or shot in fluid and the good material of biocompatibility be made, as such as by silicone, polyurethane, Biopure tM, Kraton tM, Pebax tMor Santoprene tMin any one or several materials make.This particle release causes due to mechanical stress or due to self moving of causing of material itself.In addition, barrier film 25 must be soft and resilient, correctly to realize valve and/or pumping function.
In addition, the liquid conveying system for peritoneal dialysis also comprises one or several flow-sensint unit (not shown), and the position of flow-sensint unit is preferably entrance or the outlet of arranging pump near filling.The type of flow-sensint unit can be selected as required.Such as, can be mechanical, such as turbine flowmeter can be quality formula, such as thermal flowmeter, can also be electronics or magnetic.
As preferably, the described liquid conveying system for peritoneal dialysis also comprises control device 31, as shown in Figure 10, described control device 31 is connected with described first via pressure transducer 21, second road pressure transducer 22, the 3rd road pressure transducer 23, electrohydraulic valve actuator machine 14 and the row's of filling pump 6 with the pressure of each passage of Real-Time Monitoring and according to relation regulating valve electrohydraulic valve actuator machine 14 and the row's of the filling pump 6 in time between the pressure of the row's of filling passage 1, liquid feeding channel 2 and waste discharge passage 3 or each channel pressure.In the present embodiment, described control device is also connected with according to the temperature control valve drive motors 14 of dialysis solution and the row's of filling pump 6 with described temperature sensor 19.Above scheme achieves the automatic control of the liquid conveying system of peritoneal dialysis, makes the action of three-way valve 4 in time and reliably, avoids operator and forget or delay operating the problem produced.
Three road pressure transducers and the control device of the present invention's design have following effect: the first, real-time dynamic monitoring injection pressure and Intraabdominal pressure and between pressure differential prevent the liquid stream of pouring into abdominal cavity from causing intraperitoneal to produce too high pressure to ensure the safety of patient.Second, as previously mentioned, independently pressure value change or the change of the pressure difference value between it of above-mentioned three road pressure transducers can be utilized, realize dynamic adjustments and fill with the flow velocity of row's pump 6 and the turned on or off of real-time control three-way valve 4, wherein further comprises when the position of patient relative to peritoneal dialysis machine (APD) and the change in location of dialyzate bag, and carry out feedback control by adjustment flow velocity when causing perfusion intraperitoneal liquid stream to produce too high pressure.3rd, in the discharge process of peritoneal dialysis, the change of pressure reduction between pipeline inner pressure numerical value and pipeline can be utilized, the mathematical model of a dynamic correlation is set up with output, to ensure that perfusion intraperitoneal liquid stream is in a safe pressure threshold range all the time, or ensure that the Intraabdominal accumulative fluid flow of perfusion is in a safe traffic threshold range all the time.
As preferably, the flow transducer of described control device and the described row of filling passage, liquid feeding channel and/or waste discharge channel setting and/or weight sensor and/or optical pickocff are connected.
Liquid conveying system for peritoneal dialysis of the present invention can be arranged to pipeline type, namely, the described row of filling passage 1, liquid feeding channel 2 and waste discharge passage 3 are made up of the tube for transfusion be tightly connected with described three-way valve, and be tightly connected with three-way valve 4, the row's of filling pump 6, temperature sensor and pressure transducer, as shown in Figure 1.Wherein, described filling row passage 1, liquid feeding channel 2, waste discharge passage 3 and three-way valve 4 are made up of medical-grade plastics material.
Liquid conveying system for peritoneal dialysis of the present invention integratedly can also be set to a replaceable cartridge, namely, described filling row passage 1, liquid feeding channel 2, waste discharge passage 3, pump line, three-way valve are integrated in a replaceable cartridge, as shown in Figure 10, during use, replaceable cartridge is matched with other devices.Described barrier film device is according to its above-mentioned design principle, also can be incorporated into or design in cartridge, temperature sensor directly can measure the temperature of dialysis solution by barrier film 25, pressure transducer can be distinguished directly by the pressure in barrier film 25 measurement filling row passage 1, liquid feeding channel 2, waste discharge passage 3 and mutual pressure reduction.According to the change of pressure differential pressure and cartridge fixed volume, the present invention also can accurately calculate the groundwater increment of dialysis solution, output, and effectively controls the pressure in patient abdominal cavity.
The present invention also provides a kind of operational approach of the liquid conveying system for peritoneal dialysis, comprises following operator scheme:
Fill-up mode: be communicated with the row's of filling passage and human abdominal cavity, regulating three-way valve makes filling row passage communicate with liquid feeding channel, between waste discharge passage and liquid feeding channel and waste discharge passage and fill with and arrange between passage and cut off, the rotation direction of row's pump is filled with in adjustment, the rotation direction of filling row pump makes liquid enter filling from dialyzate bag by liquid feeding channel and three-way valve under the effect of the row's of filling pump and arranges passage and the abdominal cavity flowing to human body, thus realizes dialysis solution to be injected in human abdominal cavity;
Waste discharge pattern: regulating three-way valve makes filling arrange passage and waste discharge channel connection, liquid feeding channel and filling are arranged between passage and between liquid feeding channel and waste discharge passage and are all cut off, make the rotation direction of filling row pump contrary with the operative orientation under fill-up mode, Intraabdominal liquid is sequentially passed through under the effect of the row's of filling pump, and passage is arranged in filling, three-way valve enters waste discharge passage and flows out, thus realizes Intraabdominal waste liquid to excrete.
As preferably, also there is the pattern of pipeline being carried out to pre-flush before fill-up mode, be specially: close the row's of filling pump, regulating three-way valve makes liquid feeding channel arrange passage be communicated with mutually with waste discharge passage with filling, dialysis solution flows into the row's of filling passage and waste discharge passage discharging from dialyzate bag respectively through liquid feeding channel, realizes the pre-flush to pipeline.
The present invention also provides the another kind of operational approach for the liquid conveying system of peritoneal dialysis, in this kind of peritoneal dialysis treatment device, have control device, and control device at least can control the action of three-way valve and the row's of filling pump, comprises following operator scheme:
Fill-up mode: be communicated with the row's of filling passage and human abdominal cavity, regulating three-way valve makes filling row passage communicate with liquid feeding channel, between waste discharge passage and liquid feeding channel and waste discharge passage and fill with and arrange between passage and cut off, the rotation direction of row's pump is filled with in adjustment, the rotation direction of filling row pump makes dialysis solution enter filling from dialyzate bag by liquid feeding channel and three-way valve under the effect of the row's of filling pump and arranges passage and the abdominal cavity flowing to human body, thus realizes dialysis solution to be injected in human abdominal cavity;
Waste discharge pattern: regulating three-way valve makes filling arrange passage and waste discharge channel connection, liquid feeding channel and filling are arranged between passage and between liquid feeding channel and waste discharge passage and are all cut off, make the rotation direction of filling row pump contrary with the operative orientation under fill-up mode, Intraabdominal liquid is sequentially passed through under the effect of the row's of filling pump, and passage is arranged in filling, three-way valve enters waste discharge passage and flows out, thus realizes Intraabdominal waste liquid to excrete;
In fill-up mode, detect the pressure of liquid feeding channel by first via pressure transducer and/or detect the row's of filling channel pressure by the second road pressure transducer and feed back to control device, when pressure value reaches the first setting value, the liquid conveying system that control device controls to be used for peritoneal dialysis enters waste discharge pattern.
Or in fill-up mode, detect the pressure of liquid feeding channel by first via pressure transducer and pressure value is sent to control device, detect the pressure of the row's of filling passage by the second road pressure transducer and pressure value is sent to control device, control device calculates the pressure of liquid feeding channel and the pressure difference therebetween of the row's of filling passage, when difference reaches the second setting value, the liquid conveying system that control device control device controls to be used for peritoneal dialysis enters waste discharge pattern.
In addition, by temperature sensor detect liquid feeding channel or fill with row passage in dialysis solution temperature and by temperature value transmission control device, when temperature value exceeds set point, control device regulating three-way valve makes liquid feeding channel and waste discharge channel connection make filling arrange between passage with liquid feeding channel simultaneously and the row's of filling passage is not all communicated with between waste discharge passage, thus dialysis solution is discharged through liquid feeding channel, three-way valve and waste discharge passage; Or when temperature value exceeds set point, the liquid conveying system that control device controls to be used for peritoneal dialysis enters waste discharge pattern.
As preferably, the data that control device can transmit according to the flow transducer on the row's of filling passage and/or weight sensor and/or optical pickocff calculate the amount of the dialysis solution of each dialysis perfusion and the dialysis solution cumulative amount of perfusion of repeatedly dialysing.Also arrange the amount of the dialysis solution of each perfusion by arranging control device, when groundwater increment reaches the numerical value of setting, control device stops perfusion, and according to medical treatment need maintain the standby of a period of time.After stand-by time, control device regulating three-way valve and the row's of filling pump, make the whole liquid conveying system for peritoneal dialysis forward waste discharge pattern to from fill-up mode.
Control device according to the data that the flow transducer on the row's of filling passage and/or weight sensor and/or optical pickocff transmit calculate each perfusion institute pour into the dialysis solution in human abdominal cavity amount and repeatedly perfusion institute pour into the dialysis solution cumulative amount in human abdominal cavity, control device can calculate the cumulative amount of the amount of the waste liquid of each waste discharge discharge and the waste liquid of repeatedly waste discharge discharge according to the data that the flow transducer on waste discharge passage and/or weight sensor and/or optical pickocff transmit.Certainly, the data that control device also can transmit according to the flow transducer on liquid feeding channel and/or weight sensor and/or optical pickocff calculate the amount of at every turn pouring into the dialysis solution supplied and repeatedly pour into the dialysis solution cumulative amount supplied.
Under ideal case, make liquid feeding channel, fill with row passage be not communicated with all mutually with waste discharge passage, and close fill with arrange pump.
In the present invention, the setting of the first setting value, the second setting value and stand-by time can set according to the situation of the basic general knowledge of those skilled in the art and patient, and setting value also can according to circumstances regulate accordingly.
Above embodiment is only exemplary embodiment of the present invention, and be not used in restriction the present invention, protection scope of the present invention is defined by the claims.Those skilled in the art are in essence of the present invention and protection domain, and the various amendment make the present invention or equivalent replacement also drop in protection scope of the present invention.

Claims (25)

1. the liquid conveying system for peritoneal dialysis, it is characterized in that: passage is arranged in the filling comprised for being connected with human abdominal cavity, for the liquid feeding channel that the waste discharge passage being carried out from the liquid that intraperitoneal is discharged by the row's of filling passage discharging is connected with the liquid bag be used for hold dialysis solution, described filling row passage, waste discharge passage and liquid feeding channel are connected correspondingly with three liquid stream ports of three-way valve and connection in realizing passage at least between two between each two respective channel under a certain state, described filling row passage is also provided with the row's of filling pump, described filling row pump is two-way pump, to control the row of filling passage liquid stream direction, described three-way valve comprises valve body and spool, described spool has at least three and communicates with each other and through liquid flowing channel, described valve body is provided with three with two liquid flowing channels each in the liquid flowing channel between two of described liquid flowing channel at the corresponding described liquid stream port be communicated with of different conditions.
2. the liquid conveying system for peritoneal dialysis according to claim 1, it is characterized in that: between described at least two respective channel the connection of a certain state comprise fill with row passage be communicated with between waste discharge passage, the row's of filling passage is communicated with between liquid feeding channel, be communicated with between liquid feeding channel with waste discharge passage, or passage and being communicated with between waste discharge passage and liquid feeding channel three passages are arranged in filling.
3. the liquid conveying system for peritoneal dialysis according to claim 2, it is characterized in that: the valve body of described three-way valve is the cylindric valve body with inner core, the spool of described three-way valve is the inwall being positioned at described valve body and being close to described valve body, relative to the cylindrical spool that described valve body rotates, described spool has three and communicates with each other and through described liquid flowing channel, three described liquid flowing channels form "T"-shaped or " Y " shape in the projection of horizontal plane, and the length of T-shaped or Y shape two arm portions is equal with the length of vertical section, described valve body is provided with three with two liquid flowing channels each in the liquid flowing channel between two of described liquid flowing channel at the corresponding described liquid stream port be communicated with of different conditions.
4. the liquid conveying system for peritoneal dialysis according to claim 3, it is characterized in that: when three described liquid flowing channels form " Y " in the projection of horizontal plane, angle between the projection of wherein two liquid flowing channels is 60 °, and the angle between the projection of the projection of another liquid flowing channel and these two liquid flowing channels is 150 °.
5. the liquid conveying system for peritoneal dialysis according to claim 3 or 4, is characterized in that: described spool is connected with the driving device driving described Spool rotating, and described driving device is electrohydraulic valve actuator machine or mechanical energy rotary apparatus.
6. the liquid conveying system for peritoneal dialysis according to any one of claim 1-4, is characterized in that: described filling row pump is peristaltic pump or membrane pump.
7. the liquid conveying system for peritoneal dialysis according to claim 5, it is characterized in that: the described row's of filling passage is provided with at least one for detecting the first via pressure transducer of the pressure in the described row of filling passage, described first via pressure transducer is between abdominal cavity and the row's of filling pump, described liquid feeding channel is provided with at least one for detecting the second road pressure transducer of the pressure in described liquid feeding channel, and described waste discharge passage is provided with at least one for detecting the 3rd road pressure transducer of the pressure in described waste discharge passage.
8. the liquid conveying system for peritoneal dialysis according to claim 7, is characterized in that: described first via pressure transducer and described filling are arranged between passage, between described second road pressure transducer and described liquid feeding channel and between described 3rd road pressure transducer and described waste discharge passage and be equipped with barrier film device.
9. the liquid conveying system for peritoneal dialysis according to claim 8, it is characterized in that: described filling row passage, liquid feeding channel and/or waste discharge passage are also provided with at least one for detecting the temperature sensor of the temperature of dialysis solution, and/or described filling is arranged passage, liquid feeding channel and/or is provided with barrier film device between waste discharge passage and the temperature sensor being located at this passage.
10. the liquid conveying system for peritoneal dialysis according to claim 9, it is characterized in that: described filling row passage, waste discharge passage and/or liquid feeding channel are provided with at least one flow transducer and/or weight sensor and/or optical pickocff, between each passage and the flow transducer be located on this passage and/or weight sensor and/or optical pickocff, be provided with barrier film device.
11. liquid conveying systems for peritoneal dialysis according to claim 9 or 10, it is characterized in that: described barrier film device comprises housing and is positioned at the barrier film of described housing, the lumen segmentation that described housing surrounds becomes and fills with second chamber of arranging the first chamber that passage or liquid feeding channel or waste discharge passage be connected and being connected with described temperature sensor or described first via pressure transducer or the second road pressure transducer or the 3rd road pressure transducer by described barrier film.
12. liquid conveying systems for peritoneal dialysis according to claim 11, is characterized in that: described barrier film is made by being discharged into the material that in fluid, also biocompatibility is good without the granule come off or shot.
13. liquid conveying systems for peritoneal dialysis according to claim 12, is characterized in that: described barrier film is made up of any one material in silicone or polyurethane.
14. liquid conveying systems for peritoneal dialysis according to claim 10, it is characterized in that: the liquid conveying system of described peritoneal dialysis also comprises control device, described control device and described first via pressure transducer, the second road pressure transducer, the 3rd road pressure transducer, driving device and filling are arranged pump and are connected with according to the relation accessory drive between the pressure of the row's of filling passage, liquid feeding channel and waste discharge passage or each channel pressure and/or the row's of filling pump.
15. liquid conveying systems for peritoneal dialysis according to claim 14, is characterized in that: described control device is also connected with according to the temperature accessory drive of dialysis solution and/or the row's of filling pump with described temperature sensor.
16. liquid conveying systems for peritoneal dialysis according to claim 15, is characterized in that: the flow transducer of described control device and the described row of filling passage, service duct and waste discharge channel setting and/or weight sensor and/or optical pickocff are connected.
17., according to the liquid conveying system for peritoneal dialysis any one of in claim 1-4 or any one of claim 7-10 or according to any one of claim 12-16, is characterized in that: the described row of filling passage, liquid feeding channel and waste discharge passage are made up of the tube for transfusion be tightly connected with described three-way valve.
18. liquid conveying systems for peritoneal dialysis any one of claim 1-4 or any one of claim 7-10 or according to any one of claim 12-16, is characterized in that: described filling row passage, liquid feeding channel, waste discharge passage and three-way valve are integrated in a replaceable cartridge.
The operational approach of the liquid conveying system for peritoneal dialysis according to any one of 19. claim 1-18, is characterized in that, comprises following operator scheme:
Fill-up mode: regulating three-way valve makes filling row passage communicate with liquid feeding channel, between waste discharge passage and liquid feeding channel and waste discharge passage and fill with and arrange between passage and cut off, the rotation direction of row's pump is filled with in adjustment, and the rotation direction of the row's of filling pump makes liquid enter the row's of filling passage from dialyzate bag by liquid feeding channel and three-way valve under the effect of the row's of filling pump;
Waste discharge pattern: regulating three-way valve makes filling arrange passage and waste discharge channel connection, liquid feeding channel and filling are arranged between passage and between liquid feeding channel and waste discharge passage and are all cut off, make the rotation direction of filling row pump contrary with the operative orientation under fill-up mode, waste liquid is sequentially passed through under the effect of the row's of filling pump, and passage is arranged in filling, three-way valve enters waste discharge passage and flows out.
20. operational approach according to claim 19, it is characterized in that, also there is the pattern of pipeline being carried out to pre-flush before fill-up mode, be specially: regulating three-way valve makes liquid feeding channel arrange passage be communicated with mutually with waste discharge passage with filling, dialysis solution flows into the row's of filling passage and waste discharge passage discharging from dialyzate bag respectively through liquid feeding channel, realizes the pre-flush to pipeline.
The operational approach of 21. liquid conveying systems for peritoneal dialysis according to claim 16, is characterized in that, comprise following operator scheme:
Fill-up mode: regulating three-way valve makes filling row passage communicate with liquid feeding channel, between waste discharge passage and liquid feeding channel and waste discharge passage and fill with and arrange between passage and cut off, the rotation direction of row's pump is filled with in adjustment, and the rotation direction of the row's of filling pump makes dialysis solution enter the row's of filling passage from dialyzate bag by liquid feeding channel and three-way valve under the effect of the row's of filling pump;
Waste discharge pattern: control device regulating three-way valve makes filling arrange passage and waste discharge channel connection, liquid feeding channel and filling are arranged between passage and between liquid feeding channel and waste discharge passage and are all cut off, make the rotation direction of filling row pump contrary with the operative orientation under fill-up mode, waste liquid is sequentially passed through under the effect of the row's of filling pump, and passage is arranged in filling, three-way valve enters waste discharge passage and flows out;
In fill-up mode, detect the pressure of liquid feeding channel by first via pressure transducer and/or detected the row's of filling channel pressure by the second road pressure transducer and fed back to control device, described control device controls the action of three-way valve and the row's of filling pump.
22. operational approach according to claim 21, is characterized in that, when the pressure of liquid feeding channel and/or the row's of filling channel pressure numerical value reach the first setting value, the liquid conveying system that control device controls to be used for peritoneal dialysis enters waste discharge pattern.
23. operational approach according to claim 21, is characterized in that, control device calculates the pressure of liquid feeding channel and the pressure difference therebetween of the row's of filling passage, and the liquid conveying system that control device controls to be used for peritoneal dialysis enters waste discharge pattern.
24. operational approach according to any one of claim 21-23, it is characterized in that, by temperature sensor detect liquid feeding channel or fill with row passage in dialysis solution temperature and by temperature value transmission control device, when temperature value exceeds set point, control device regulating three-way valve makes liquid feeding channel and waste discharge channel connection make filling arrange between passage with liquid feeding channel simultaneously and the row's of filling passage is not all communicated with between waste discharge passage, thus dialysis solution is discharged through liquid feeding channel, three-way valve and waste discharge passage; Or when temperature value exceeds set point, the liquid conveying system that control device controls to be used for peritoneal dialysis enters waste discharge pattern.
25. operational approach according to any one of claim 21-23, it is characterized in that, control device calculates the dialysis solution of each perfusion amount according to the data that the flow transducer on the row's of filling passage and/or weight sensor and/or optical pickocff transmit and the dialysis solution cumulative amount repeatedly poured into, control device can calculate amount and the repeatedly waste discharge cumulative amount of waste liquid of discharging of the waste liquid that each waste discharge is discharged according to the data that the flow transducer on waste discharge passage and/or weight sensor and/or optical pickocff transmit.
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