CN103751762A - Product for promoting skin cell reconstruction and delaying senescence - Google Patents
Product for promoting skin cell reconstruction and delaying senescence Download PDFInfo
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- CN103751762A CN103751762A CN201410037339.9A CN201410037339A CN103751762A CN 103751762 A CN103751762 A CN 103751762A CN 201410037339 A CN201410037339 A CN 201410037339A CN 103751762 A CN103751762 A CN 103751762A
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Abstract
The invention belongs to the technical field of traditional Chinese medicines, and relates to a product for promoting skin cell reconstruction and delaying senescence. The product is prepared from the following raw materials by weight: 6-12 parts of ginseng, 1-5 parts of tremella polysaccharide, 2-6 parts of oat peptides, 2-9 parts of pueraria isoflavone, 1-8 parts of soy isoflavone and 0.5-2 parts of sweetening agents. Experimental results show that the herb composition provided by the invention can obviously promote and improve skin metabolism to enable skins to be tender, smooth, more elastic and glossier, and has the functions of delaying senescence, whitening and removing freckles.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, relate to specifically a kind of take promotion skin cell restructuring that Chinese herbal medicine prepared as raw material product that can slow down aging.
Background technology
The traditional Chinese medical science thinks that the composition of human body has skin, arteries and veins, meat, muscle, bone outward, inside has the vital organs of the human body, and the contact in length and breadth of meridians, QI and blood, has formed an organic whole.Therefore skin and internal organs have close relationship.Especially very close with the relation of lung.The traditional Chinese medical science has very strong advantage aspect promoting blood circulation to remove obstruction in the collateral, benefiting vital QI and blood and transfer healthy energy, has and promotes QI-blood circulation, clean blood vessel access, regulates blood hemal ring to reduce blood fat and blood viscosity, regulates blood circulation, enhances metabolism and the effect of catharsis and toxin expelling.
The traditional Chinese medical science is thought " lung governing skin and hair ".The a surname of human body by lung qi sends out with respectful and falls, and makes qi-blood-body fluid be able to spreading whole body.If with the passing of time pulmonary function not normal, scaly dry skin, with a haggard face and pale.The people of the deficiency of the lung, xerosis cutis and lackluster, with a haggard face.Lung and spleen kidney are interrelated, taste the foundation of acquired constitution, source of generating QI and blood.The spleen has the function to transport and transform nutrients, main muscle, with the lung is concerned with QI of the whole body, kidney is congenital, but must spleenization the nourishing of angry blood, only have lung spleen normal renal function, will the full skin of QI and blood ruddy, make skin Lightening skin healthy.
Summary of the invention
The object of the invention is to overcome prior art deficiency, and provide, a kind of curative effect is fast, expense is low, having no side effect effectively promotes the product of skin cell restructuring energy slow down aging.
For realizing object of the present invention, existing according to following technical scheme.This product is to be made by the raw material of following weight portion proportioning: 6～12 parts of Radix Ginsengs, 1～5 part of tremella polysaccharide, 2～6 parts of oat peptides, 2～9 parts of Radix Puerariae isoflavones and 1～8 part of soybean isoflavone, 0.5～2 part of sweeting agent.
Radix Ginseng (Panax ginseng C.A. Mey.) is Araliaceae.As traditional medicinal herbs most in use, there is the history of thousands of years, in countries in the world extensive use.Radix Ginseng strongly invigorating primordial QI, multiple arteries and veins is admittedly de-, and invigorating the spleen to benefit the lung, promotes the production of body fluid, and calms the nerves.Radix Ginseng herbaceos perennial, the weather that happiness is shady and cool, moistening, grows in the theropencedrymion or shaw of height above sea level gentle slope, 500～1100 meters of mountain regions that day and night temperature is little or slope land more.Because root is loose, if shape spindle often has bifurcated, overall picture is people's head, hands, foot and extremity quite seemingly, so be called Radix Ginseng.Ancient times Radix Ginseng refined Rhizoma Polygonati, Herba Stellariae Saxatilis, the SHENCAO of being called.Radix Ginseng is called " king of BAICAO " by people, be one of well-known " northeast three essentials-essence " (Radix Ginseng, fur, Cornu Cervi Pantotrichum), be have won fame both at home and abroad, rare medicinal herbs that old children all knows.This is most important, one of the famousst and precious qi-invigorating herb, and sweet in the mouth, micro-hardship, slightly warm in nature, has invigorating QI to relieve exhaustion, spleen invigorating lung benefiting, mind calming Fructus Alpiniae Oxyphyllae, the effect of nourishing blood to promote the production of body fluid.Function strongly invigorating primordial QI, intelligent promoting and the mind tranquilizing, is the good merchantable brand of tonification health care.Studies confirm that, Radix Ginseng has the human body cell of promotion to grow, increase the effect of frequency dividing cell, and American scholar is taught Fu Like and is thought, human body cell approximately division just stops fourth 50 times, the each division of cell once needs 2.4 years, if can reach division 50 times, just can live 120 years old, due to Radix Ginseng strongly invigorating primordial QI, can be usually used in shallow breathing, extreme cold of the limbs, faint and weak pulse, the diseases such as shock that blood pressure is low. in addition, because Radix Ginseng has the strong effect of tonification, can defying age, be applicable to weakness due to chronic disease, cardiopalmus severe palpitation, spontaneous perspiration and cold extremities, breathe hard, collapse, heart failure, the diseases such as neurasthenia.Modern study confirmation, Radix Ginseng contains multiple Saponin and volatile oil, polysaccharide, the compositions such as vitamin B I, B2, C; Nervous system is had to good regulating action, have short gonadotropic Effect, also have cardiotonic; Can reduce blood glucose, strengthen hematopoietic function, adrenal cortex reinforcing function, improves the body adaptive capacity of environment to external world, improves immunologic function.In addition, Radix Ginseng also can promote the synthetic of protein, suppresses the generation of hypercholesterolemia, and the rehabilitation of chronic disease is had to facilitation.
In Radix Ginseng, contain ginsenoside and ginseng polysaccharide.Especially ginsenoside Rb2 has obvious hypoglycemic activity, and ginseng polysaccharide's (or glycopeptide class) is another kind of blood sugar reducing component in Radix Ginseng in addition.Radix Ginseng is containing multiple Saponin and polysaccharide composition, the leachate of Radix Ginseng can slowly absorb by skin, to skin without any pessimal stimulation, energy skin expansion blood capillary, promote cutaneous circulation, increase skin-nourishing, the water oil balance of regulation of skin, prevent skin dehydration, sclerosis, wrinkling, adhere to for a long time using the product containing Radix Ginseng, can strengthen skin elasticity, cell is obtained newborn.Radix Ginseng active substance also has the reducing property of check melanin simultaneously, makes skin pure white smooth.Its beauty treatment effectiveness is innumerable, is the superfine product of improving looks.
Herba bromi japonici is the ancient cereal crops that originate from China, belongs to grass family Avena in plant classification.According to Chinese Academy Of Preventive Medicine Research Institute Of Nutrition And Food Hygiene to the analysis result avenin matter of composition of food and fatty content in cereal crops all containing the first, in avenin matter, contain 18 seed amino acids, wherein 8 kinds is the aminoacid of needed by human.Research shows that micromolecular bioactive peptide can be absorbed by the body better than macromolecular protein free amino acid, has adjusting immunity, regulates hormone, antioxidation, and the effects such as resisting fatigue, may be used in health food.In addition, the biologically active polypeptide that research is found adds in cosmetics and skincare product, plays defying age, moisturizing, the effects such as Whitening, speckle removing, acne removing.Herba bromi japonici, except having natural health care, also has very high its cosmetic values.People have understood that utilizing Herba bromi japonici to treat xerosis cutis and fully recover from an illness itches very early.According to archeologist, investigate, ancient egypt queens and princesses just have the custom of Herba bromi japonici water washing bath.In Herba bromi japonici, contain avenin, oat peptide, Herba bromi japonici wet goods composition.There is anti-oxidation efficacy, increase skin activity, delaying skin aging, whitening skin and preserving moisture, minimizing wrinkle mottle, antiallergic, etc. effect.In countries such as the U.S., Japan, Canada, France, claim that Herba bromi japonici is " family doctor ", " plant gold ", " natural cosmetologist ".Herba bromi japonici delicate fragrance free from extraneous odour.Utilize modern biotechnology enzyme engineering, protein dissociation in bran of Fagopyrum esculentum Moench is become to small-molecular peptides, closely similar with epithelical cell growth factor (EGF), being easy to skin absorbs, can accelerate cell proliferation, promote skin metabolism, Cucumber Extract, reduce skin coarseness, make skin shine delicate and charming elegance.Relative other protein hydrolysates, characteristic pure, abnormal smells from the patient delicate fragrance that Herba bromi japonici small-molecular peptides has, is also the green succedaneum of good animal polypeptide.Small-molecular peptides enters skin inside, plays the effect of Moisture factor, can soften skin, pins moisture of skin, gives skin and moistens.There is reduce wrinkle, accelerate cell proliferation and metabolism.Reduce skin coarseness, Cucumber Extract.The function of removing free radical, makes skin keep young state.Moisturizing, crease-resistant, whitening and speckle dispelling slow down aging.Can use as dosage forms such as cream frost, emulsion, essence, gel, astringent, facial films.
Semen sojae atricolor originates in Chinese crops, is the leguminous plant that a kind of its seed contains rich in protein and oils and fats.It is one of primary raw material of some traditional foods.But also contain the various bioactivators such as oligosaccharide, isoflavone.Soybean isoflavone wherein, has weak estrogen activity, and its health benefit to human body has been subject to people's common concern.Soybean isoflavone is polyphenol compound, mainly comprises daiazi, Dai, genistin, genistein, Glycitein, daidzin.Research shows: genistein (isoflavone) contained in Semen sojae atricolor can suppress a kind of enzyme that stimulates tumor growth, stops the growth of tumor, anti-curing cancers, especially breast carcinoma, carcinoma of prostate, colon cancer.Soybean isoflavone has the different physiological roles such as antitumor, angiocardiopathy preventing, osteoporosis, radioprotective, antioxidation.Semen sojae atricolor is to help to overcome prostatosis to male's obvious benefit.
Tremella is that China's economic worth is high, and precious a kind of edible fungi and medicinal fungus, is traditional edible and medicinal fungi.Polysaccharide is most important constituent, accounts for 60% ~ 70% of its dry weight, and meanwhile, tremella polysaccharide is a kind of important bioactive substance.Numerous achievements in research show, tremella polysaccharide can obviously reduce the content of free cholesterol, cholesteryl ester in hyperlipidemia, serum, and the obvious immunologic function of enhancing body promotes Hepatocyte Glycogen synthetic and antitumor, mutation, radioprotective and leukocyte increasing.Long-term taking tremella polysaccharide can reduce blood pressure, blood fat, prevents arteriosclerosis, suppresses tumor, enhancing human body immunity function.Tremella polysaccharide is extracted in experiment from Tremella with water extraction, by orthogonal experiment Optimized Extraction Process, and its beauty and skin care effect is studied, and tremella polysaccharide has the ability of certain removing hydroxyl radical free radical, can be used as defying age composition and is applied in cosmetics.Performance of keeping humidity research also proves that the moistening effect of tremella polysaccharide is better than glycerol and trehalose.So as functional component, added tremella polysaccharide in external many cosmetics of super quality.List of references: Yang Shihai, Yin Chunmei, the progress of the red tremella polysaccharide of Miao Shuan and pharmacological action thereof.
Radix Puerariae is the dry root of leguminous plant Pueraria lobata (Willd.) Ohwi.Practise and claim Herba Gelsemii Elegantis.Sweet in the mouth, property is pungent, cool, returns spleen, stomach warp.Be good at expelling pathogenic factors from muscles for reducing heat, the rash of promoting the production of body fluid, yang invigorating antidiarrheal.Be mainly used in treating fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.The effective site of kudzuvine root for treating cardiovascular and cerebrovascular disease is Radix Puerariae total flavones, and effective ingredient mainly contains puerarin, daidzein, daidzin, seven material lignin etc.That the pharmacological action of Radix Puerariae has is antipyretic, blood sugar lowering, Fructus Alpiniae Oxyphyllae, improve cerebral circulation, arrhythmia, resist myocardial ischemia, reduce myocardial oxygen consumption and without obviously negative inotropic action, also there is antithrombotic, improve the effects such as high density lipoprotein, vasospasm and reduction platelet aggregation.
Described sweeting agent is that oligosaccharides is as oligomeric isomaltose, oligomeric galactose, Oligomeric maltose, oligofructose etc.; Sugar alcohols is as maltose alcohol, Sorbitol, dew sugar alcohol, xylitol, erythritol etc.; Natural sweetener is as sweet protein, stevioside, glycyrrhizin etc.
The said goods can also add pharmaceutically acceptable excipient to make the regular dosage form pharmaceutically such as tablet, capsule, granule or oral liquid, or makes the common beverages such as beverage, teabag.
Another object of the present invention is to provide the preparation method of this product, and Radix Ginseng obtains Radix Ginseng extract dry powder after adopting suitable solvent extraction, then with tremella polysaccharide, oat peptide, Radix Puerariae isoflavone, soybean isoflavone, sweeting agent is mixed to get active component, then makes by preparation interpolation adjuvant.
Described solvent preferred water, ethanol or its mixture.
Radix Ginseng extract dry powder, tremella polysaccharide, oat peptide, Radix Puerariae isoflavone, soybean isoflavone and sweeting agent also can directly mix to incapsulate to be taken, or the Radix Ginseng in above-mentioned composition can with suitable solvent respectively or mixed extraction processing obtain its extract, total extract is made preparation with pharmaceutical excipient hybrid process again.Described solvent refers to pharmaceutically conventional solvent, preferred water, ethanol or its combination, and extracting method can extract by pharmaceutically conventional method, as decocting method, percolation, reflux extraction, continuous extraction etc.
During for oral administration, conventional solid preparation be can be made into, capsule, tablet, granule, pill and oral solution etc. comprised.Tablet means disc-shaped that medicine and the compacting of suitable auxiliary materials and mixing form or the solid preparation of special-shaped lamellar; Tablet be take oral ordinary tablet as main, separately has Sublingual tablet, buccal tablet, mouth paster, chewable tablet, dispersible tablet, effervescent tablet, fuse, enteric coatel tablets, controlled release tablet and slow releasing tablet etc.Capsule means medicine or is added with adjuvant filling in Capsules or is sealed in the solid preparation in soft capsule material; Capsule, according to its dissolving and release characteristics, can be divided into hard capsule (being commonly referred to as capsule), soft capsule (soft gelatin capsule), slow releasing capsule, controlled release capsule and enteric coated capsule.Granule means that medicine and suitable adjuvant make the dried particles shape preparation with certain particle size; Granule can be divided into soluble particles (being commonly referred to as granule), mix suspension grain, effervescent granule, enteric coated particles, slow-releasing granules and controlled release granule etc.Pill means that medicine evenly mixes with suitable adjuvant, the spherical or near-spherical solid preparation made from proper method; Pill comprises drop pill, sugar pill, piller etc.Oral solution means that medicine dissolution makes for oral liquid clarification preparation in suitable solvent.
The preparation of herbaceous plant compositions of the present invention can adopt the conventional method in existing pharmaceutical field to produce, and when needing, can add various pharmaceutically acceptable carriers.Described carrier comprises osmotic pressure regulator, antioxidant, pH value regulator, emulsifying agent, solubilizing agent, antibacterial, filler, suspending agent, lubricant, disintegrating agent, binding agent of pharmaceutical field routine etc.
Herbaceous plant compositions of the present invention, when making oral formulations, can add suitable binding agent, filler, lubricant, disintegrating agent etc.Filler comprises Icing Sugar, starch, calcium phosphate, calcium sulfate two water things, dextrin, microcrystalline Cellulose, mannitol, lactose, pregelatinized Starch etc.; Binding agent comprises sodium carboxymethyl cellulose, PVP-K30, hydroxypropyl cellulose, starch slurry, methylcellulose, ethyl cellulose, hypromellose, gelling starch etc.; Disintegrating agent comprises dried starch, polyvinylpolypyrrolidone, cross-linking sodium carboxymethyl cellulose, carboxymethyl starch sodium, low-substituted hydroxypropyl cellulose etc.; Sodium lauryl sulphate, micropowder silica gel, lubricant comprise magnesium stearate, Pulvis Talci etc.
Its active component of the present invention is by Radix Ginseng extract, tremella polysaccharide, oat peptide, Radix Puerariae isoflavone, soybean isoflavone forms, and experiment showed, that herbaceous plant compositions of the present invention can obviously promote and improve skin metabolism, make it tender smooth, more flexible and gloss, has played slow down aging, the effect of whitening and speckle dispelling.
The specific embodiment
The concrete content of the operation of the herbaceous plant active component water extract carrying out in specific embodiment and the excipient adding, is all ordinary skill in the art, is that those skilled in the art easily realizes, and does not have the inadequate problem that discloses.The object of embodiment is that explanation compositions of the present invention can be made regular dosage form, rather than for limiting its protection domain or affecting it openly fully.
Raw material: Radix Ginseng, tremella polysaccharide, oat peptide, Radix Puerariae isoflavone, soybean isoflavone, sweeting agent and adjuvant are commercially available prod.Radix Ginseng extracts by water, ethanol or its mixture the Radix Ginseng extract obtaining, this process using be extracting method conventional on Chinese materia medica.
Embodiment 1
Get Radix Ginseng 900g through alcohol reflux, concentrated after spraying dry, obtain Radix Ginseng extract dry powder, add tremella polysaccharide 150g, oat peptide 150g Radix Puerariae isoflavone 200g, soybean isoflavone 300g and xylitol 70g, mix pulverizing, direct filled hard capsules.
Embodiment 2
Get Radix Ginseng 800g through decocting in water extract, concentrated after spraying dry, obtain Radix Ginseng extract dry powder, add tremella polysaccharide 100g, oat peptide 200g, Radix Puerariae isoflavone 200g and soybean isoflavone 200g, mixing, granulation, oven dry, granulate, add magnesium stearate, tabletting.
Embodiment 3
Get Radix Ginseng 850g through water-ethanol (4: 6) reflux, extract,, concentrated after spraying be dried, obtain Radix Ginseng extract dry powder, add tremella polysaccharide 150g, oat peptide 200g Radix Puerariae isoflavone 200g, soybean isoflavone 200g and glycyrrhizin 100g, mix, granulate, dry, add magnesium stearate and Pulvis Talci, filled hard capsules.
Embodiment 4
Get Radix Ginseng 900g and extract to obtain Radix Ginseng extract aqueous solution through decocting in water, then add tremella polysaccharide 200g, oat peptide 300g Radix Puerariae isoflavone 300g, soybean isoflavone 300g and glycyrrhizin 150g, concentrate to obtain concentrated solution, fill, sterilizing, makes oral liquid.
Embodiment 5
Get Radix Ginseng 1000g through water-ethanol (10: 1) reflux, extract,, concentrated after spraying be dried, obtain Radix Ginseng extract dry powder, add again tremella polysaccharide 200g, oat peptide 200g, Radix Puerariae isoflavone 300g and soybean isoflavone 300g, stevioside 50g, more appropriate microcrystalline Cellulose, pregelatinized Starch, CMS-Na are added to mixing in active component, granulation, granulate, finally add magnesium stearate, tabletting.
the concrete statistical analysis of implementing
Selection is by skin problem, all ages and classes level patient 360 people carry out the test of this product function in various degree.Women 256 people wherein, male 104 people.According to the person's of taking one's test different situations, take respectively different modes (for oral administration or external) to use after the course for the treatment of of this product (30 days), wherein 326 application on human skin are dry, dark yellow, lax etc., and skin problem is obviously changed, effective percentage 90.5%.By adjusting using method, use after two courses for the treatment of of this product (60 days), 356 people's skin has clear improvement, effective percentage 98,9%.It is little that 4 people feel that skin improves, but the readme mental status makes moderate progress.
be below model case:
case 1:
* * *, man, 46 years old, long-term work was busy, had alcohol drinking patterns, caused skin dry especially, even played bits decortication.Take this product capsule every day for three times after 30 days, skin peeling plays bits phenomenon and disappears, and it is smooth that skin obviously becomes.
case 2:
* * *, female, 26 years old, professional model, due to life-time service cosmetics, facial pimpling and have cutis laxa phenomenon.Every daily facial mask cloth soaks this product oral liquid and spreads on face 30 minutes, and after 30 days, pimple disappears and skin becomes smooth flexible.
case 3:
* * *, female, 38 years old, skin have chloasma and, tarnish, in test every day this product oral of per os hora somni liquid, simultaneously every daily facial mask cloth soaks this product oral liquid and spreads on face 30 minutes, after 30 days, chloasma disappearance and facial skin are tender smooth.
case 4:
* * *, female, 21 years old, student, the black and xerosis cutis of face, due to the long pox of the large facial large area of learning pressure.Every day this product capsule for oral administration three times and soak this product oral liquid with facial mask cloth and spread on face 30 minutes, after 30 days, skin obviously bleaches and smooth moistening, small pox disappears.
case 5:
* * *, female: 34 years old, teacher.Skin of face is lax too early, canthus wrinkle weight, and every daily facial mask cloth soaks this product oral liquid and spreads on face 30 minutes, and after 30 days, wrinkle obviously attenuates and shoals, and it is flexible glossy that skin becomes.
case 6:
* * *, female, 24 years old, to treat after facial large area pustule type acne, skin leaves spot and becomes extremely dry.Every daily facial mask cloth soaks this product oral liquid and spreads on face 30 minutes, and after 30 days, spot disappears, and skin of face become compact glossy.
The present invention has the restructuring of the Skin Cell of promotion, skin nutrition cell, promotes and improve skin cell metabolism process, and the function of anti aging effect can be used for preparing antidotal skin Caring and uses.
Claims (1)
1. a product that promotes skin cell restructuring energy slow down aging, is characterized in that it is to be made by the raw material of Chinese medicine of following weight proportion:
6～12 parts of Radix Ginsengs, 1～5 part of tremella polysaccharide, 2～6 parts of oat peptides, 2～9 parts of Radix Puerariae isoflavones and 1～8 part of soybean isoflavone, 0.5～2 part of sweeting agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410037339.9A CN103751762B (en) | 2014-01-26 | 2014-01-26 | A kind ofly skin cell is promoted to recombinate and can the product of slow down aging |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410037339.9A CN103751762B (en) | 2014-01-26 | 2014-01-26 | A kind ofly skin cell is promoted to recombinate and can the product of slow down aging |
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| Publication Number | Publication Date |
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| CN103751762A true CN103751762A (en) | 2014-04-30 |
| CN103751762B CN103751762B (en) | 2015-11-18 |
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| CN201410037339.9A Expired - Fee Related CN103751762B (en) | 2014-01-26 | 2014-01-26 | A kind ofly skin cell is promoted to recombinate and can the product of slow down aging |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104161715A (en) * | 2014-06-26 | 2014-11-26 | 吴雪琴 | Preparing method and product of whitening skincare lotion |
| CN104432070A (en) * | 2014-12-22 | 2015-03-25 | 威海百合生物技术股份有限公司 | Health food for perfecting skin moisture |
| CN110693758A (en) * | 2019-10-22 | 2020-01-17 | 吉林化工学院 | Preparation and quality evaluation of compound bletilla striata facial mask |
Citations (1)
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|---|---|---|---|---|
| CN1977669A (en) * | 2005-12-05 | 2007-06-13 | 王健柏 | Flavone health-care drink product |
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2014
- 2014-01-26 CN CN201410037339.9A patent/CN103751762B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1977669A (en) * | 2005-12-05 | 2007-06-13 | 王健柏 | Flavone health-care drink product |
Non-Patent Citations (2)
| Title |
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| 庞小一等: "燕麦肽的制备、抗氧化性及其对α-淀粉酶抑制作用的研究", 《食品工业科技》, vol. 34, no. 20, 31 December 2013 (2013-12-31), pages 163 * |
| 陈飞飞等: "活性多糖延缓衰老的研究进展", 《中西医结合学报》, vol. 7, no. 7, 31 July 2009 (2009-07-31), pages 675 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104161715A (en) * | 2014-06-26 | 2014-11-26 | 吴雪琴 | Preparing method and product of whitening skincare lotion |
| CN104432070A (en) * | 2014-12-22 | 2015-03-25 | 威海百合生物技术股份有限公司 | Health food for perfecting skin moisture |
| CN110693758A (en) * | 2019-10-22 | 2020-01-17 | 吉林化工学院 | Preparation and quality evaluation of compound bletilla striata facial mask |
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| CN103751762B (en) | 2015-11-18 |
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