CN103751748A - Traditional Chinese medicinal preparation for treating chronic obstructive lung disease at remission stage - Google Patents
Traditional Chinese medicinal preparation for treating chronic obstructive lung disease at remission stage Download PDFInfo
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- CN103751748A CN103751748A CN201410020428.2A CN201410020428A CN103751748A CN 103751748 A CN103751748 A CN 103751748A CN 201410020428 A CN201410020428 A CN 201410020428A CN 103751748 A CN103751748 A CN 103751748A
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Abstract
The invention discloses a traditional Chinese medicinal preparation for treating chronic obstructive lung disease at remission stage. According to the principle of traditional Chinese medicine, blood stasis is caused by long-standing diseases, so that patients have different degrees of blood stagnation. Cough with dyspnea for a long period of time causes insufficiency of the lung and the kidney qi, and deficiency of qi fails to help heart promote blood circulation, thus blood stagnation in heart, lung and organs deteriorates. Traditional Chinese medicinal materials including Farfugium japonicum, Zingiber mioga, Nanocnide lobata, Clinacanthus nutans, Campylotropis hirtella, Sanicula astrantifolia, Companumoea root and Semen Juglandis are decocted in water to obtain decoction. According to clinical comparative trials, the total effective rate is up to 93.3%, which is significantly better than that of a control group, so that the traditional Chinese medicinal preparation is worth of clinical generalization and application.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, relate in particular to a kind of Chinese medicine preparation for the treatment of chronic obstructive pulmonary disease in remission period.
Background technology
Chronic obstructive pulmonary disease (COPD) is one group of pulmonary disease take airway obstruction dysfunction of ventilation as common feature, mainly comprises chronic bronchitis, bronchial asthma and emphysema etc.Main manifestations is out of breath, cough, expectoration and pulmonary's excessive expansion, wheezing sound etc. clinically.Because of its cause of disease complexity, outbreak repeatedly, touching difficulty more, can develop into chronic pulmonary heart disease, respiratory failure etc., has had a strong impact on patient's prognosis and life quality.At present simple western medical treatment effect is not good enough, and I find through clinical observation for many years, utilize Chinese traditional treatment chronic obstructive pulmonary disease to have good curative effect.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of chronic obstructive pulmonary disease.The traditional Chinese medical science is thought " prolonged illness must the stasis of blood ", so this type of patient exists blood stasis witness in various degree.The lighter's light purplish tongue or dark; Severe one cyanosis of the lips and nails, dim complexion, drumstick finger.Cough with asthma with the passing of time, insufficiency of QI of the lung and kidney, " qi as the commander of blood ", the deficiency of vital energy promotes blood vessels operations without the devote every effort to help heart, the each internal organs blood stasis of cardiopulmonary and whole body must increase the weight of.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment chronic obstructive pulmonary disease is made by the Chinese medicine of following weight portion: Coniogramme japonica (Thunb.) Diels 9-15 Fen, Rhizoma zingiberis miogae 20-25 part, Herba Nanocnides pilosae 15-30 part, Herba Clinacanthi Nutantis 3-9 part, Radix Campylotropis hirtellae 30-40 part, Radix Saniculae Astrantifoliae 9-15 part, Radix Campanumoeae 9-30 part, semen juglandis 9-15 part.
Preferred: Coniogramme japonica (Thunb.) Diels 12 23 parts of Fen, Rhizoma zingiberis miogae, 22.5 parts of Herba Nanocnides pilosaes, 6 parts of Herba Clinacanthi Nutantis, 35 parts of Radix Campylotropis hirtellaes, 24 parts of Radix Saniculae Astrantifoliae, 19.5 parts of Radix Campanumoeaes, 12 parts of semen juglandiss.
Preparation method: become decoction by traditional method decocting.
In side: Coniogramme japonica (Thunb.) Diels: promoting blood flow to regulate menstruation, pain relieving, eliminate the phlegm, cough-relieving; Rhizoma zingiberis miogae: promoting blood flow to regulate menstruation, relieving cough and expelling phlegm, subduing swelling and detoxicating; Herba Nanocnides pilosae: invigorate blood circulation, heat clearing away, cough-relieving; Herba Clinacanthi Nutantis: blood stasis dispelling regulating menstruation, reducing swelling and alleviating pain; Radix Campylotropis hirtellae: promoting blood flow to regulate menstruation, regulating QI to relieve pain; Radix Saniculae Astrantifoliae: reinforcing spleen and kidney, nourishing the lung to arrest cough; Radix Campanumoeae: strengthening the spleen and stomach, tonifying the lung gas, eliminate the phlegm, cough-relieving; Semen juglandis: the kidney invigorating and essence nourishing, warming the lung Dingchuan, intestine moistening.
Clinical data
1. physical data is chosen in January, 2007～2010 year December Jian Wo institute department of Chinese medicine outpatient service and Pneumology Department inpatient 64 examples, is divided at random 2 groups.Treatment group 45 examples, wherein male 32 examples, female's 13 examples; Age 36-81 year, average 53 years old; Course of disease 3-39, average 22 years.Matched group 19 examples, wherein male 13 examples, female's 6 examples; Age 40-72 year, average 49 years old; Course of disease 3-41, average 25 years.The aspects such as two groups of patient's age of onset, the course of disease, severe extent are substantially similar, and there was no significant difference (P > 0.05), has comparability.
2. diagnostic criteria all meets the < < chronic obstructive pulmonary disease diagnosis and treatment guide > > in 2002 of respiratory disease association of Chinese Medical Association diagnostic criteria, belong to the catabasis, and the person that gets rid of pulmonary heart disease.
3. two groups of cases of Therapeutic Method are all accepted COPD catabasis conventional therapy, comprise anti-bronchiectasis, eliminate the phlegm and oxygen uptake if desired, heart failure resistance treatment etc.If the diseases such as in therapeutic process, panting appears in any one group of patient, dyspnea, all can give a small amount of ammonia bitter edible plant alkali intravenous drip or salbutamol atomization to relieving asthma with spasmolytic; If this observation is exited in secondary infection.Treatment group coordinates Chinese medicine preparation of the present invention on above-mentioned treatment basis, side's medicine composition: take Coniogramme japonica (Thunb.) Diels 12g, Rhizoma zingiberis miogae 23g, Herba Nanocnides pilosae 22.5g, Herba Clinacanthi Nutantis 6g, Radix Campylotropis hirtellae 35g, Radix Saniculae Astrantifoliae 24g, Radix Campanumoeae 19.5g, semen juglandis 12g, by traditional method decocting, become decoction, 1 dose, every order, early, late each 200ml decoction being taken warmly.Two groups of patient treatments are all take 2 weeks as one course for the treatment of, add up curative effect after treating continuously 3 courses for the treatment of.
4. the evaluation of criterion of therapeutical effect comprehensive therapeutic effect is drafted according to < < new Chinese medicine guideline of clinical investigations > >.Clinic control: cough, expectorant, asthma shape and pulmonary's wheezing sound disappear substantially, it is normal that objective indicator is recovered, and life can be taken care of oneself completely.Effective: cough, expectorant, asthma shape and pulmonary's wheezing sound be clearly better, objective indicator is obviously alleviated, and self care ability improves more than 2/3.Effective: cough, expectorant, asthma shape takes a turn for the better, pulmonary's wheezing sound alleviates, and objective indicator makes moderate progress, and self care ability improves more than 1/3.Invalid: cough, expectorant, asthma shape and wheezing sound unchanged, objective indicator changes not obvious or increases the weight of, self care ability improves less than 1/3.
5. general curative effect comparison before and after two groups of patient treatments of therapeutic outcome, in Table 1.After two groups of treatments, symptom and sign all has clear improvement before treatment; And treatment group and matched group comparison have significant differences, P < 0.05.
The table 1 liang clinical total effects comparison of group
Note: with treatment group comparison, P < 0.01.
The specific embodiment
Embodiment mono-: take Coniogramme japonica (Thunb.) Diels 12g, Rhizoma zingiberis miogae 23g, Herba Nanocnides pilosae 22.5g, Herba Clinacanthi Nutantis 6g, Radix Campylotropis hirtellae 35g, Radix Saniculae Astrantifoliae 24g, Radix Campanumoeae 19.5g, semen juglandis 12g, become decoction by traditional method decocting.
Embodiment bis-: take Coniogramme japonica (Thunb.) Diels 9g, Rhizoma zingiberis miogae 20g, Herba Nanocnides pilosae 15g, Herba Clinacanthi Nutantis 3g, Radix Campylotropis hirtellae 30g, Radix Saniculae Astrantifoliae 9g, Radix Campanumoeae 9g, semen juglandis 9g, become decoction by traditional method decocting.
Embodiment tri-: take Coniogramme japonica (Thunb.) Diels 15g, Rhizoma zingiberis miogae 25g, Herba Nanocnides pilosae 30g, Herba Clinacanthi Nutantis 9g, Radix Campylotropis hirtellae 40g, Radix Saniculae Astrantifoliae 15g, Radix Campanumoeae 30g, semen juglandis 15g, become decoction by traditional method decocting.
Claims (2)
1. treat a Chinese medicine preparation for chronic obstructive pulmonary disease in remission period, it is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: Coniogramme japonica (Thunb.) Diels 9-15 part, Rhizoma zingiberis miogae 20-25 part, Herba Nanocnides pilosae 15-30 part, Herba Clinacanthi Nutantis 3-9 part, Radix Campylotropis hirtellae 30-40 part, Radix Saniculae Astrantifoliae 9-15 part, Radix Campanumoeae 9-30 part, semen juglandis 9-15 part.
2. a kind of Chinese medicine preparation for the treatment of chronic obstructive pulmonary disease in remission period according to claim 1, is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: Coniogramme japonica (Thunb.) Diels 12 23 parts of Fen, Rhizoma zingiberis miogae, 22.5 parts of Herba Nanocnides pilosaes, 6 parts of Herba Clinacanthi Nutantis, 35 parts of Radix Campylotropis hirtellaes, 24 parts of Radix Saniculae Astrantifoliae, 19.5 parts of Radix Campanumoeaes, 12 parts of semen juglandiss.
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Citations (4)
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| CN1066788A (en) * | 1992-07-01 | 1992-12-09 | 王勇 | The method for making of body-strengthening nutrient oral liquid and purposes in the Asia |
| CN101069544A (en) * | 2007-06-12 | 2007-11-14 | 贵州神奇集团控股有限公司 | Milk-honey fruit-jelly making method |
| CN102379442A (en) * | 2010-10-26 | 2012-03-21 | 曲靖师范学院 | Szechwan-Yunnan sanicle root functional drink and preparation method thereof |
| CN103404684A (en) * | 2013-09-01 | 2013-11-27 | 张凤平 | Processing method for preserved mioga gingers |
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2014
- 2014-01-09 CN CN201410020428.2A patent/CN103751748A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1066788A (en) * | 1992-07-01 | 1992-12-09 | 王勇 | The method for making of body-strengthening nutrient oral liquid and purposes in the Asia |
| CN101069544A (en) * | 2007-06-12 | 2007-11-14 | 贵州神奇集团控股有限公司 | Milk-honey fruit-jelly making method |
| CN102379442A (en) * | 2010-10-26 | 2012-03-21 | 曲靖师范学院 | Szechwan-Yunnan sanicle root functional drink and preparation method thereof |
| CN103404684A (en) * | 2013-09-01 | 2013-11-27 | 张凤平 | Processing method for preserved mioga gingers |
Non-Patent Citations (3)
| Title |
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| 吕佳康: "慢性阻塞性肺疾病中药新药临床研究指导原则制定的可行性探讨", 《中国临床药理学杂志》 * |
| 李文瑞，李秋贵主编，史学军等编写: "《中药别名辞典》", 30 September 1994, article "活血莲 锈钉子", pages: 733 - 1041 * |
| 李经纬，邓铁涛等主编: "《中医大辞典》", 31 May 1995, article "毛花点草", pages: 1364 * |
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Application publication date: 20140430 |