CN103751393A - Formula of Equine piroplasmosis treatment drug - Google Patents

Abstract

The present invention provides a formula of an Equine piroplasmosis treatment drug. The drug comprises the following raw material herbs: melia toosendan, bupleurum chinense, lychee seed, fennel, frankincense, notopterygium incisum and heracleum hemsleyanum. According to the present invention, spleen-stomach warming, coldness expelling, qi benefiting and splenic yang invigorating are adopted as the treatment principle, the formula is reasonable, the preparation process is simple, and the application range is wide; and the drug is prepared from the pure Chinese herbs, and has characteristics of wide source, low cost, high cure rate, no drug residue and no toxic-side effect, especially the plant cell wall is damaged at a maximum after ultrafine crushing, the defects of high crude fiber content and difficult effective component dissolution of the traditional drug powder are solved, and the drug is easily absorbed by horses, has effects of significant relieving, pain relieving, body function regulating and effective foal scrotum hernia treatment, and further provides characteristics of convalescent period shortening and no recurrence compared with the western medicine treatment.

Description

A kind of medicament composing prescription for the treatment of equus giardiasis

Technical field

The present invention relates to technology of pharmaceutical engineering field, relate in particular to a kind of medicament composing prescription for the treatment of equus giardiasis.

Background technology

Horse giardiasis is to parasitize caused bloodprotozoonoses in the erythrocyte of equus by Babesia caballi and Babesia equi.The clinical acute symptoms of weight such as high heat, anemia, jaundice, hemorrhage and dyspnea that present, as diagnosis and treatment, mortality rate is high not in time.Primary disease is propagated by hard Ticks, and therefore popular have a given area property and a seasonality.The sick Major Epidemic of China Babesia caballi in northeast, east Inner Mongolia and Qinghai Area.Babesiasis equi Major Epidemic in Xinjiang, West Inner Mongolia and southern each province.

The disease symptom of sick horse generally comprises spirit depressing, and hair is slightly random, jaundice, anemia etc.

Therapeutic Method, horses should stop usage immediately.Give digestible feedstuff, the treatments such as available imidazophenylurea, three nitrogen miaows, Placenta Hominis indigo plant.But drug side effect used is larger, and life-time service easily develops immunity to drugs.The medicine for the treatment of by Chinese herbs equus giardiasis also emerges.

Summary of the invention

Technical problem to be solved by this invention is, overcomes the medicament composing prescription that prior art provides a kind for the treatment of equus giardiasis of effective reduction toxic and side effects.

In order to solve the problems of the technologies described above, the invention provides a kind of medicament composing prescription for the treatment of equus giardiasis, described Chinese medicine composition comprises following raw medicinal material: Fructus Toosendan, Radix Bupleuri, Semen Litchi, Fructus Foeniculi, Olibanum, Rhizoma Et Radix Notopterygii and Radix Angelicae Pubescentis.

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine composition is preferably, 20～30 parts of 20～30 parts of Fructus Toosendans, 15～25 parts of Radix Bupleuri, 15～25 parts of Semen Litchis, 15～25 parts, Fructus Foeniculi, 7～15 parts of Olibanums, 7～15 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine composition can also be, 24～26 parts of 24～26 parts of Fructus Toosendans, 19～21 parts of Radix Bupleuri, 19～21 parts of Semen Litchis, 19～21 parts, Fructus Foeniculi, 9～11 parts of Olibanums, 9～11 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.

The ratio of weight and number of the kind raw medicinal material in described Chinese medicine composition also can be preferably, 25 parts of 25 parts of Fructus Toosendans, 20 parts of Radix Bupleuri, 20 parts of Semen Litchis, 20 parts, Fructus Foeniculi, 10 parts of Olibanums, 10 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.

Described Chinese medicine composition can further include Fructus Evodiae, and the ratio of weight and number of described Fructus Evodiae is 15～20 parts.Be preferably 18 parts.

Described Chinese medicine composition can further include the Radix Astragali, Rhizoma Cimicifugae, Radix Ginseng and the Rhizoma Atractylodis Macrocephalae, and ratio of weight and number is respectively Radix Astragali 15-20 part, 15～20 parts of Rhizoma Cimicifugaes, Radix Ginseng 8-15 part and Rhizoma Atractylodis Macrocephalae 10-15 part.Be preferably 12 parts of 16 parts of the Radixs Astragali, 16 parts of Rhizoma Cimicifugaes, 10 parts of Radix Ginsengs and the Rhizoma Atractylodis Macrocephalaes.

The present invention also provides the preparation method of the medicament composing prescription of above-mentioned any one treatment equus giardiasis, and the preparation method of described Chinese medicine composition is,

Step 1: take various raw medicinal materials according to percentage by weight, mix, be ground into powder, granularity is 20-200 order;

Step 2: to the yellow wine that adds 90 ~ 110 parts in the powder of step 1, mix homogeneously.

Wherein, the granularity in described step 1 is preferably 150-200 order.

The present invention provides again the preparation method of the medicament composing prescription of above-mentioned any one treatment equus giardiasis, and the preparation method of described Chinese medicine composition comprises the following steps,

The first step, is mixed in proportion described component, is ground into powder;

Second step, obtains powder by the first step and adds in cold water and soak 6 hours～12 hours, and with slow fire boiling, decocting time is 3 hours～5 hours, and decoction liquor is filtered, and obtains the first filtrate, and the quality of the water adding is 2～4 times of the powder quality that obtains of the first step;

The 3rd step, the filtering residue that second step filter is obtained adds in cold water again, with slow fire boiling 2 hours～4 hours, filters and obtains the second filtrate, and the quality of the water adding is 2～4 times of the powder quality that obtains of second step;

The 4th step, the second filtrate that the first filtrate that second step is obtained and the 3rd step obtain is mixed, and concentrating under reduced pressure, except anhydrating, dry, pulverize powdered, and granularity is 20～200 orders;

The 5th step, to the yellow wine that adds 90 ~ 110 parts in the powder of the 4th step, mix homogeneously.

Wherein, the granularity in described the 5th step is preferably 150-200 order.

Wherein, the unit of above-mentioned various raw medicinal materials " part " is preferably " g ", and the unit of yellow wine " part " is preferably " ml ".

Beneficial effect of the present invention: it is the rule for the treatment of that warming spleen and stomach for dispelling cold, benefiting qi and raising yang are take in the present invention, reasonable recipe, preparation technology is simple, applied widely.The present invention adopts pure Chinese medicinal herbs to make, wide material sources, cost are low, cure rate is high, medicine noresidue, have no side effect, particularly after micronizing, destroy to greatest extent plant cell wall, solved the deficiency that traditional drugs powder crude fiber content is high, effective ingredient is difficult to stripping, be easier to horses and absorb.There is the effect of the analgesia of releiving significantly and adjusting body function, effectively treat young coltfoal scrotum hernia, shorten the period of convalescence with western medicine phase specific energy, and do not recur.

The specific embodiment

The invention provides a kind of medicament composing prescription for the treatment of equus giardiasis, described Chinese medicine composition comprises following raw medicinal material: Fructus Toosendan, Radix Bupleuri, Semen Litchi, Fructus Foeniculi, Olibanum, Rhizoma Et Radix Notopterygii and Radix Angelicae Pubescentis.

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine composition is preferably, 20～30 parts of 20～30 parts of Fructus Toosendans, 15～25 parts of Radix Bupleuri, 15～25 parts of Semen Litchis, 15～25 parts, Fructus Foeniculi, 7～15 parts of Olibanums, 7～15 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine composition can also be, 24～26 parts of 24～26 parts of Fructus Toosendans, 19～21 parts of Radix Bupleuri, 19～21 parts of Semen Litchis, 19～21 parts, Fructus Foeniculi, 9～11 parts of Olibanums, 9～11 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.

The ratio of weight and number of the kind raw medicinal material in described Chinese medicine composition also can be preferably, 25 parts of 25 parts of Fructus Toosendans, 20 parts of Radix Bupleuri, 20 parts of Semen Litchis, 20 parts, Fructus Foeniculi, 10 parts of Olibanums, 10 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.

Described Chinese medicine composition can further include Fructus Evodiae, and the ratio of weight and number of described Fructus Evodiae is 15～20 parts.Be preferably 18 parts.

Described Chinese medicine composition can further include the Radix Astragali, Rhizoma Cimicifugae, Radix Ginseng and the Rhizoma Atractylodis Macrocephalae, and ratio of weight and number is respectively Radix Astragali 15-20 part, 15～20 parts of Rhizoma Cimicifugaes, Radix Ginseng 8-15 part and Rhizoma Atractylodis Macrocephalae 10-15 part.Be preferably 12 parts of 16 parts of the Radixs Astragali, 16 parts of Rhizoma Cimicifugaes, 10 parts of Radix Ginsengs and the Rhizoma Atractylodis Macrocephalaes.

The present invention also provides the preparation method of the medicament composing prescription of above-mentioned any one treatment equus giardiasis, and the preparation method of described Chinese medicine composition is,

Step 1: take various raw medicinal materials according to percentage by weight, mix, be ground into powder, granularity is 20-200 order;

Step 2: to the yellow wine that adds 90 ~ 110 parts in the powder of step 1, mix homogeneously.

Granularity in described step 1 is preferably 150-200 order.

The present invention provides again the preparation method of the medicament composing prescription of above-mentioned any one treatment equus giardiasis, and the preparation method of described Chinese medicine composition comprises the following steps,

The first step, is mixed in proportion described component, is ground into powder;

Second step, obtains powder by the first step and adds in cold water and soak 6 hours～12 hours, and with slow fire boiling, decocting time is 3 hours～5 hours, and decoction liquor is filtered, and obtains the first filtrate, and the quality of the water adding is 2～4 times of the powder quality that obtains of the first step;

The 3rd step, the filtering residue that second step filter is obtained adds in cold water again, with slow fire boiling 2 hours～4 hours, filters and obtains the second filtrate, and the quality of the water adding is 2～4 times of the powder quality that obtains of second step;

The 4th step, the second filtrate that the first filtrate that second step is obtained and the 3rd step obtain is mixed, and concentrating under reduced pressure, except anhydrating, dry, pulverize powdered, and granularity is 20～200 orders;

The 5th step, to the yellow wine that adds 90 ~ 110 parts in the powder of the 4th step, mix homogeneously.

Granularity in described the 5th step is preferably 150-200 order.

The pharmacology of described each component is as follows:

Fructus Toosendan: claim again chinaberry reality, Fructus Toosendan, core Fructus Jujubae, Fructus Toosendan, chinaberry, the stone Fructus Evodiae, Fructus Toosendan tree, Fructus Toosendan reality etc.Cold in nature, bitter in the mouth; Slightly poisonous.Return liver, small intestinal, urinary bladder channel.Energy soothing liver-QI, promoting the circulation of QI to relieve pain, anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.

Radix Bupleuri: another name: Asia puecon recklessly, smoke < < Sheng Nong's herbal classic > >, mountain dish, eat careless < < WU Pu Bencao > >, faggot < < product converge essence and want > >.Cold nature, bitter in the mouth, pungent; GUIXIN bag, liver, gallbladder, tri-jiao channel.Evacuation is brought down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.For fever caused by exogenous pathogens, the diseases such as the internal organs prolapsus of collapse of QI.Cure mainly: cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus comes off, menoxenia.

Semen Litchi: this product is the dry mature seed of sapindaceous plant Fructus Litchi Litchi chinensisSonn..Pluck mature fruit summer, remove peel and meat aril, clean, dry.Have another name called that litchi props up, red litchi, beautiful branch.Warm in nature, sweet in the mouth, micro-hardship.Enter liver, kidney channel.Promoting QI to circulate and dispersing the agglomeration of the pathogens, cold-dispelling pain-relieving.For colic of cold type stomachache, painful and swollen testis.

Fructus Foeniculi: claim again Fructus Foeniculi, bosom perfume, fragrant silk dish.Acrid in the mouth, warm in nature.Enter kidney, bladder, stomach warp.Energy warming the liver kidney, stimulating appetite, the cold expelling of regulating the flow of vital energy, has supporing yang road.Cure mainly: cold in middle-JIAO, loss of appetite, nausea and vomiting, abdominal part cold type of pain; Hernia pain, painful and swollen testis; Stagnation of QI in spleen and stomach, distension and fullness in the abdomen is had a pain etc.

Olibanum: smoked Lu Xiang, horse hair is fragrant, nipple is fragrant, the perfume (or spice) that collapses, it pool is fragrant, Moller is fragrant, many gals Luo Xiang etc.Acrid in the mouth, hardship, warm in nature.Enter the heart, liver, spleen channel.Invigorate blood circulation, circulation of qi promoting, pain relieving, detumescence and promoting granulation.For traumatic injury, skin infection carbuncle, congestion blocks all diseases etc.< < does not record > >: treat edema due to wind pathogen poison swollen, remove bad odor.Treat the urticaria poison of itching.< < Bencao Shiyi > >: treat deaf, apoplexy locked mouth, married woman's vim and vigour, can send out wine, manage air-cooledly, stop large intestine and let out Bleach, treat all skin ulcers and make internal diabetes.

Rhizoma Et Radix Notopterygii: You Cheng Qiang is blue or green, protect the envoy of Qiang, recklessly king envoy, Qiang sliding, move back wind envoy, black powder.Acrid in the mouth, hardship; Warm in nature.Enter bladder, kidney channel.Loose exterior cold; Wind-damp dispelling; Profit joint; Pain relieving.Main affection of exogenous wind-cold; Have a headache lossless; Mimeograph cold-damp numbness; Edema due to wind pathogen edema; Sore swollen toxin.For impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea; External curing vitiligo, alopecia areata.The cold expelling that induces sweat, expelling wind and dampness, pain relieving.

Radix Angelicae Pubescentis: have another name called recklessly king envoy, solely shake grass, solely cunning, Sempervivum tectorum, RADIX ANGELICAE PUBESCENTIS from Sichuan of China, meat Radix Angelicae Pubescentis, qualifications and record of service Qiu's Radix Angelicae Pubescentis, the east of Sichuan Radix Angelicae Pubescentis, fragrant Radix Angelicae Pubescentis, achievement Radix Angelicae Pubescentis, Radix Angelicae Dahuricae (Radix Heraclei Scabridi), mountain Radix Angelicae Dahuricae (Radix Heraclei Scabridi), beautiful work.Acrid in the mouth, hardship, slightly warm in nature.Return liver, kidney, urinary bladder channel.Expelling wind and dampness; Dispersing cold for relieving pain.For anemofrigid-damp arthralgia; Lumbocrural pain; Few cloudy volt wind headache, headache toothache.

Yellow wine: be field of medicaments, very important adjuvant or " extra conductant ingredient " in the field of Chinese medicines particularly.Help blood circulation, enhance metabolism, there is blood-enriching face-nourishing, the effect of the cold relieving of invigorating blood circulation, dredge the meridian passage, effectively the cold resisting stimulation, preventing cold.

Fructus Evodiae: another name Koji, volt spicy, smelly lake, Fructus Evodiae, tea are peppery, paint spicy, smelly spicy tree, the deep and remote son of Zuo Lichun, rice spicy etc.Acrid in the mouth, hardship, hot in nature; Slightly poisonous.Return liver, spleen, stomach, kidney channel.Dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.For headache due to JUE YIN disorder, colic of cold type stomachache, the disturbance of lower legs due to pathogenic cold and dampness, dysmenorrhea, abdominal pain during menstruation, abdominal distention, vomiting acid regurgitation, Diarrhoea, external treatment aphtha; Hypertension.

The Radix Astragali: latin name Astragali Radix, sweet in the mouth, warm in nature, enter spleen, lung meridian, there is tonification spleen soil, elevate a turnable ladder yang-energy, strengthening superficial resistance to stop perspiration, the effect of holder skin ulcer granulation promoting, cures mainly the weak anorexia and loose stool due to deficiency of both the splenic and pulmonary QI, shortness of breath and palpitation, the visceroptosis of sinking of QI of middle-JIAO, the metrorrhagia of QI failing to control blood is had blood in stool, chronic diarrhea proctoptosis; The spontaneous sweating of exterior deficiency, the cards such as insufficiency of vital energy and blood.The Radix Astragali strengthens heart contraction ability, can improve the blood circulation of whole body, can coronary artery dilator, kidney blood vessel and Rhizoma Bistortae peripheral vessel, make cutaneous circulation vigorous; Can improve the nonspecific immunity power of body, protect the liver and fall hypoglycemic effect, staphylococcus, blood dissolubility streptococcus, Diplococcus pneumoniae, dysentery bacterium etc. are had to inhibitory action, the Radix Astragali can appreciable impact splenocyte Information Conduction, realizes immunoregulation effect.

Rhizoma Cimicifugae: have another name called big cattle card holder, Radix Longan, hole root of the tooth.Acrid in the mouth, micro-sweet, cold nature.Return lung, spleen, stomach, large intestine channel.Deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.For headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome is sent out speckle; Proctoptosis, uterine prolapse.

Radix Ginseng: SHANSHEN, Park Ginseng, people's rank, Coprinus atramentarius (Bull.) Fr. (Coprinus sterquilinus Fr.), wooden club, Rhizoma Panacis Japonici, SHENCAO, Sphallerocarpus gracilis, Herba Wedeliae Wallichii, Herba Stellariae Saxatilis, hundred chi pestles, extra large fat, the beautiful door screen of golden well, Radix Ginseng etc.Sweet in the mouth, micro-hardship, slightly warm in nature.Return spleen, lung, the heart, kidney channel.Strongly invigorating primordial QI, multiple arteries and veins is admittedly de-, and invigorating the spleen to benefit the lung, promotes the production of body fluid and nourishes blood, the Fructus Alpiniae Oxyphyllae of calming the nerves.For weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, deficiency of qi and blood, prolonged illness is empty wins, palpitation with fear insomnia, sexual impotence official is cold.Cure mainly: impairment caused by overstrain is deficient, lack of appetite, asthenia, regurgitation are told food, stool lingering diarrhea, empty cough with asthma are short, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition, quench one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion and prolonged deficiency multiple, the disease of all qi-blood-body fluid deficiencies.

The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, the cards such as frequent fetal movement; The Rhizoma Atractylodis Macrocephalae have adjust gastrointestinal motility function, antiulcer, protect the liver, the effect such as enhancing human body immunity function, anti-stress, enhancing hemopoietic function; Its dampness diuretic effect is relevant with diuresis; And antiabortive effect is relevant with the effect of inhibition uterine contraction.The Rhizoma Atractylodis Macrocephalae also has the effects such as antioxidation, slow down aging, blood sugar lowering, anticoagulation, antitumor.

Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.

Embodiment 1:

Fructus Toosendan 25g, Radix Bupleuri 20g, Semen Litchi 20g, Fructus Foeniculi 20g, Olibanum 10g, Rhizoma Et Radix Notopterygii 10g and Radix Angelicae Pubescentis 25g.Mix, be ground into powder, granularity is 200 orders; In powder, add 100ml yellow wine, mix homogeneously.During use, gavage.

Embodiment 2:

Fructus Toosendan 24g, Radix Bupleuri 19g, Semen Litchi 19g, Fructus Foeniculi 20g, Olibanum 9g, Rhizoma Et Radix Notopterygii 9g, Radix Angelicae Pubescentis 24g and Fructus Evodiae 18g.Mix, be ground into powder, granularity is 180 orders; In powder, add 90ml yellow wine, mix homogeneously.During use, gavage.

Embodiment 3:

Fructus Toosendan 26g, Radix Bupleuri 21g, Semen Litchi 21g, Fructus Foeniculi 19g, Olibanum 10g, Rhizoma Et Radix Notopterygii 11g, Radix Angelicae Pubescentis 26g, Radix Astragali 16g, Rhizoma Cimicifugae 16g, Radix Ginseng 10g and Rhizoma Atractylodis Macrocephalae 12g.Preparation method comprises the following steps:

The first step, is mixed in proportion various raw medicinal materials, is ground into powder;

Second step, obtains powder by the first step and adds in cold water and soak 10 hours, and with slow fire boiling, decocting time is 4 hours, and decoction liquor is filtered, and obtains the first filtrate, and the quality of the water adding is 4 times of the powder quality that obtains of the first step;

The 3rd step, the filtering residue that second step filter is obtained adds in cold water again, with slow fire boiling 3 hours, filters and obtains the second filtrate, and the quality of the water adding is 3 times of the powder quality that obtains of second step;

The 4th step, the second filtrate that the first filtrate that second step is obtained and the 3rd step obtain is mixed, and concentrating under reduced pressure, except anhydrating, dry, pulverize powdered, and granularity is 150 orders;

The 5th step, to the yellow wine that adds 100ml in the powder of the 4th step, mix homogeneously.During use, gavage.

Acute toxicity test:

120 of application NIH mices, SPF level, male and female half and half, body weight 18～22g, carries out acute toxicity testing.Mice is divided into three groups at random, be that (concentration is 6.28g crude drug/ml for the Chinese medicine composition of matched group, the administration embodiment of the present invention 1, maximum concentration) (concentration is 6.28g crude drug/ml for administration group 1 and the administration embodiment of the present invention 4, the administration group 2 of Chinese medicine composition maximum concentration), before experiment, fasting is 12 hours.Administration group 1 and administration group 2 are dissolved in water the Chinese medicinal powder of embodiments of the invention 1 and embodiment 4 preparations to mouse stomach respectively, gavage volume is 5ml/kg (being that single-dose dosage is 31.4g crude drug/kg), matched group gives equivalent normal saline, administration in 1 day 2 times, delivery time 6 hours, after administration, Continuous Observation is 14 days, and records toxic reaction and the death toll of mice.Experimental result shows: with matched group comparison, after administration, mice has no notable difference, experiment Continuous Observation 14 days, mice overall health of patients, ingest, drinking-water, body weight gain is all normal.Therefore Chinese medicine acute toxicity of the present invention is low, clinical drug safety.

Clinical trial:

Chinese medicine composition avirulence of the present invention, easy to use, can directly gavage or add in feedstuff and use.During application, Chinese medicine composition of the present invention directly can be gavaged by per kilogram of body weight 0.4g crude drug, or mix and in feedstuff, feed young coltfoal, and statistical data demonstration, generally can fully recover for the continuous 4-20 of taking days, and treatment time is short, clinical cure rate reaches 95%, and cure rate is high.

All above-mentioned these intellectual properties of primary enforcement, do not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.

The above, be only preferred embodiment of the present invention, is not the present invention to be done to the restriction of other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not depart from, any simple modification, equivalent variations and the remodeling above embodiment done according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (10)

1. a medicament composing prescription for the treatment of equus giardiasis, is characterized in that, described Chinese medicine composition comprises following raw medicinal material: Fructus Toosendan, Radix Bupleuri, Semen Litchi, Fructus Foeniculi, Olibanum, Rhizoma Et Radix Notopterygii and Radix Angelicae Pubescentis.

2. the medicament composing prescription for the treatment of equus giardiasis as claimed in claim 1, it is characterized in that: the ratio of weight and number of the various raw medicinal materials in described Chinese medicine composition is 20～30 parts of 20～30 parts of Fructus Toosendans, 15～25 parts of Radix Bupleuri, 15～25 parts of Semen Litchis, 15～25 parts, Fructus Foeniculi, 7～15 parts of Olibanums, 7～15 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.

3. the medicament composing prescription for the treatment of equus giardiasis as claimed in claim 1 or 2, it is characterized in that: the ratio of weight and number of the various raw medicinal materials in described Chinese medicine composition is 24～26 parts of 24～26 parts of Fructus Toosendans, 19～21 parts of Radix Bupleuri, 19～21 parts of Semen Litchis, 19～21 parts, Fructus Foeniculi, 9～11 parts of Olibanums, 9～11 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.

4. the medicament composing prescription of the treatment equus giardiasis as described in claims 1 to 3, it is characterized in that: the ratio of weight and number of the kind raw medicinal material in described Chinese medicine composition is 25 parts of 25 parts of Fructus Toosendans, 20 parts of Radix Bupleuri, 20 parts of Semen Litchis, 20 parts, Fructus Foeniculi, 10 parts of Olibanums, 10 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.

5. the medicament composing prescription of the treatment equus giardiasis as described in claim 1 to 4, is characterized in that: described Chinese medicine composition also further comprises Fructus Evodiae, and the ratio of weight and number of described Fructus Evodiae is 15～20 parts.

6. the medicament composing prescription of the treatment equus giardiasis as described in claim 1 to 5, it is characterized in that: described Chinese medicine composition also further comprises the Radix Astragali, Rhizoma Cimicifugae, Radix Ginseng and the Rhizoma Atractylodis Macrocephalae, ratio of weight and number is respectively Radix Astragali 15-20 part, 15～20 parts of Rhizoma Cimicifugaes, Radix Ginseng 8-15 part and Rhizoma Atractylodis Macrocephalae 10-15 part.

7. the medicament composing prescription of the treatment equus giardiasis as described in claim 1 to 6, is characterized in that: the preparation method of described Chinese medicine composition is,

Step 1: take various raw medicinal materials according to percentage by weight, mix, be ground into powder, granularity is 20-200 order;

Step 2: to the yellow wine that adds 90 ~ 110 parts in the powder of step 1, mix homogeneously.

8. the medicament composing prescription for the treatment of equus giardiasis as claimed in claim 7, is characterized in that: the granularity in described step 1 is 150-200 order.

9. the medicament composing prescription of the treatment equus giardiasis as described in claim 1 to 6, is characterized in that:

The preparation method of described Chinese medicine composition comprises the following steps,

The first step, is mixed in proportion described component, is ground into powder;

Second step, obtains powder by the first step and adds in cold water and soak 6 hours～12 hours, and with slow fire boiling, decocting time is 3 hours～5 hours, and decoction liquor is filtered, and obtains the first filtrate, and the quality of the water adding is 2～4 times of the powder quality that obtains of the first step;

The 3rd step, the filtering residue that second step filter is obtained adds in cold water again, with slow fire boiling 2 hours～4 hours, filters and obtains the second filtrate, and the quality of the water adding is 2～4 times of the powder quality that obtains of second step;

The 4th step, the second filtrate that the first filtrate that second step is obtained and the 3rd step obtain is mixed, and concentrating under reduced pressure, except anhydrating, dry, pulverize powdered, and granularity is 20～200 orders;

The 5th step, to the yellow wine that adds 90 ~ 110 parts in the powder of the 4th step, mix homogeneously.

10. the medicament composing prescription for the treatment of equus giardiasis as claimed in claim 9, is characterized in that: the granularity in described the 5th step is 150-200 order.