CN103735466B - A kind of galangal hydrolat healthcare collutory and preparation method thereof - Google Patents
A kind of galangal hydrolat healthcare collutory and preparation method thereof Download PDFInfo
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- CN103735466B CN103735466B CN201410019033.0A CN201410019033A CN103735466B CN 103735466 B CN103735466 B CN 103735466B CN 201410019033 A CN201410019033 A CN 201410019033A CN 103735466 B CN103735466 B CN 103735466B
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Abstract
The present invention relates to a kind of healthcare collutory of galangal hydrolat, belong to cosmetics of everyday use preparing technical field; Specifically by weight portion be 35-65% galangal hydrolat, 0.1-2% deodorant tune, 0.1-0.5% cosolvent and antifreeze, 1-5% wetting agent and water forms; Its preparation process is for first to prepare galangal hydrolat, the galangal plant material of fresh drying process is put into water steam extract in fractionating device, utilize water vapour to carry out by the stronger quintessence oil of volatilization, make it to form the vapor phase containing quintessence oil, recycling temp-difference condensing becomes liquid condition, thus isolate hydrosol water, add galangal hydrolat after then menthol, Tween 80, glycerol being mixed successively, stir, add distilled water again to stir, filtration sterilization, bottling, to obtain final product; It is antibacterial that the galangal hydrolat collutory adopting the present invention to prepare has deodorization, and fragrant refreshment, the curative effect of preventing or arresting vomiting, mouthfeel is good, and safety non-toxic is easy to use, and technique is simple.
Description
Technical field
The present invention relates to a kind of collutory and preparation method thereof, is more particularly healthcare collutory of a kind of galangal hydrolat and preparation method thereof, belongs to cosmetics of everyday use preparing technical field.
Background technology
Rhizoma Alpiniae Officinarum (
rhizoma Alpiniaeofficinarum), call high Rhizoma Zingiberis Recens, Rhizoma Alpiniae Officinarum, quite Rhizoma Zingiberis Recens and Fructus Citri Sarcodactylis root etc., for Zingiberaceae Alpinia herbaceos perennial Rhizoma Alpiniae Officinarum (
alpinia officinarumhance) rhizome, main product is in counties and cities such as the Xuwens of Zhanjiang.Rhizoma Alpiniae Officinarum medicinal history is long, and history tree is all on the books, begins to be loaded in " Mingyi Bielu ", is classified as middle product; Go through version " Chinese Pharmacopoeia " all to record, be one of " ten large wide medicines ".In [2002] No. 51 " notice about further specification healthy food material management " adnexaes 1 that Ministry of Public Health is announced, Rhizoma Alpiniae Officinarum is listed in and has been food and the article list of medicine.Rhizoma Alpiniae Officinarum is used for the treatment of oral disease as compound Chinese herbal medicinal ingredients and health care can trace back to the Song dynasty the earliest, " 101 choosing side " hesitates to move forward loose: " control wind to have a toothache bitterly; be regardless of for a long time new, also control the cheek and swell and ache: Rhizoma Alpiniae Officinarum one piece (about two cun), Scorpio one piece (drying on watt).Upper is end.To point some medicines, as medicinal in tooth, it is thorough to wipe order heat, and the moment spues few saliva, gargles with salt soup.”
Modern common Rhizoma Alpiniae Officinarum pulverizing or extracting solution enter remedy,toothache, peppery, puckery, the ugly restriction of color Long-term clinical verify curative effect Rhizoma Alpiniae Officinarum oral cavity health preparation not accept by masses.Except peppery, remove astringent taste, the technique such as decolouring all needs trial to do technological improvement, process is loaded down with trivial details, and effective ingredient runs off large.
Rhizoma Alpiniae Officinarum volatile oil (also known as Rhizoma Alpiniae Officinarum quintessence oil) transparent yellow, has special Rhizoma Zingiberis Recens fragrance, the fragrant refreshment of energy, deodorization preventing or arresting vomiting.Gui Shuhua etc. prove that Rhizoma Alpiniae Officinarum volatile oil has stronger fungicidal activities (Pericarpium Zanthoxyli, Rhizoma Alpiniae Officinarum volatile oil extracorporeal antifungal activity are studied, Chinese Chinese medicine information magazine, 2005,12(8) .) can to simplify than Rhizoma Alpiniae Officinarum Aqueous extracts etc. remove astringent taste, decoloration process.
Also known as crystal's oil, hydrosol refers to that quintessence oil is in distillation extraction process, a kind of 100% saturated distillation stock solution separated when refining quintessence oil, be a kind of side-product of quintessence oil, composition is natural pure.Except containing except a small amount of derived essential oil in hydrosol, also containing the water-soluble substances in majority of plant body, the flavonoid contained by it etc. are that quintessence oil is short of.Due to the characteristic of its low concentration, gentle non-stimulated, completely without essence and alcoholic content, there are akin effect and effect with plants essential oil itself.Galangal hydrolat has concurrently outside the advantage of Rhizoma Alpiniae Officinarum quintessence oil, can simplify except peppery technique than Rhizoma Alpiniae Officinarum quintessence oil.
This type of vapor extraction thing there is not yet and is applied in oral hygiene composition.Therefore, develop a kind of technique simple, deodorization is antibacterial, the galangal hydrolat healthcare collutory of fragrant refreshment preventing or arresting vomiting, not only can simplify except peppery, remove astringent taste, the technique such as decolouring, have also been enlarged the range of application of Rhizoma Alpiniae Officinarum and enrich oral cavity health formulation products.
Summary of the invention
The object of this invention is to provide a kind of healthcare collutory of galangal hydrolat, not only technique is simple, and it is antibacterial to have deodorization, fragrant refreshment, the curative effect of preventing or arresting vomiting, and mouthfeel is good, and safety non-toxic is easy to use.
In order to solve the problem, the technical solution adopted in the present invention is:
A healthcare collutory for galangal hydrolat, is made up of the component of following weight portion:
Galangal hydrolat 35-65%
Deodorant tune 0.1-2%
Cosolvent and antifreeze 0.1-0.5%
Wetting agent 1-5%
Distilled water surplus.
In described galangal hydrolat, volatile oil accounts for 0.4% ~ 0.6%.
Described deodorant tune is menthol.
Described cosolvent and antifreeze are Tween 80.
Described wetting agent is glycerol.
A preparation method for the healthcare collutory of galangal hydrolat, comprises the steps:
(1) preparation of galangal hydrolat: galangal hydrolat takes from the elite of fractional distillation in Rhizoma Alpiniae Officinarum quintessence oil distillation extraction process, the galangal plant material of fresh drying process is put into water steam to be extracted in fractionating device, water vapour is utilized to carry out by the stronger quintessence oil of volatilization, make it to form the vapor phase containing quintessence oil, recycling temp-difference condensing becomes liquid condition, thus isolate hydrosol water, whole still-process carries out in closed system.
(2) preparation of galangal hydrolat healthcare collutory: add galangal hydrolat after menthol, Tween 80, glycerol being mixed successively, stir, then add distilled water and stir, filtration sterilization, bottling, to obtain final product.
The galangal hydrolat of preparation is carried out gaschromatographic mass spectrometry detection:
1 instrument
SHIMADZU QP-20110 Plus gas chromatograph-mass spectrometer (Japanese Shimadzu Corporation)
2 GC-MS analysis conditions
Chromatographic column is VFWAXms capillary column (30m × 0.25mm × 0.25 μm, Agilent company of the U.S.); Temperature programming: initial temperature 60 DEG C, keeps 10min, rises to 220 DEG C, rise to 240 DEG C with the speed of 20 DEG C/min with the speed of 4 DEG C/min; Splitless injecting samples, injector temperature 250 DEG C; Mass spectrum adopts electronics bombardment (EI) ion source, interface temperature 250 DEG C, ion source temperature 200 DEG C, scan mode: full scan, mass scan range 40-450
m/z; Solvent delay 3.5min.
date processing
Employing mass spectrography is qualitative, and gas chromatogram carries out relative quantification (area normalization method).Mass spectrum retrieval adopts NIST Chemical Structures (American National Standards Institute, the 8th edition) storehouse and Wiley Library (William's spectrum library, the 9th edition) storehouse, carries out component qualitative in conjunction with related data.The results are shown in Figure material representated by peak in 1, figure number as following table:
The invention has the beneficial effects as follows:
(1) galangal hydrolat involved in the present invention, take from the elite of fractional distillation in Rhizoma Alpiniae Officinarum quintessence oil distillation extraction process, be rich in the multiple natural component such as natural essence, tannin, abnormal smells from the patient is fresh and clean, also containing the multiple precious composition being insoluble to oils and fats, quality better; And character as mild as a dove, in product, safety does not stimulate.
(2) galangal hydrolat is used in collutory, having deodorization antibacterial, fragrant refreshment, the curative effect of preventing or arresting vomiting by the present invention, and without the need to adding antiseptic, coloring agent, plasticizer, saves cost of supplementary product, the safety problem that additive capable of reducing using brings.
(3) this preparation method technique is simple, and with low cost, the product safety of preparation is nontoxic, easy to use, is applicable to large-scale promotion.
For this invention, We conducted production practices, using the chloromycetin of broad-spectrum antiseptic as positive control, test the galangal hydrolat described in collutory of the present invention and (lowest concentration of drug supplied needed for examination microorganism of 99.9% is killed to commonly encountered diseases bacteria strain minimum inhibitory concentration (MIC, μ g/mL), minimum bactericidal concentration in oral cavity.MBC, μ g/mL), the results are shown in Table 1:
The bacteriostatic experiment of table 1 galangal hydrolat
Accompanying drawing explanation
Fig. 1 is that galangal hydrolat GCMS TIC schemes.
Detailed description of the invention
Be described in further details the present invention below by embodiment, these embodiments are only used for the present invention is described, do not limit the scope of the invention.
embodiment 1
A healthcare collutory for galangal hydrolat, is made up of the component of following weight portion:
Galangal hydrolat (volatile oil accounts for 0.4% ~ 0.6%) 35%
Menthol 2%
Tween 80 0.5%
Glycerol 5%
Distilled water surplus.
A preparation method for the healthcare collutory of galangal hydrolat, comprises the steps:
(1) preparation of galangal hydrolat: galangal hydrolat takes from the elite of fractional distillation in Rhizoma Alpiniae Officinarum quintessence oil distillation extraction process, the galangal plant material of fresh drying process is put into water steam to be extracted in fractionating device, water vapour is utilized to carry out by the stronger quintessence oil of volatilization, make it to form the vapor phase containing quintessence oil, recycling temp-difference condensing becomes liquid condition, thus isolate hydrosol water, whole still-process carries out in closed system;
(2) preparation of galangal hydrolat healthcare collutory: add galangal hydrolat after menthol, Tween 80, glycerol being mixed successively, stir, then add distilled water and stir, filtration sterilization, bottling, to obtain final product.
embodiment 2
A healthcare collutory for galangal hydrolat, is made up of the component of following weight portion:
Galangal hydrolat (volatile oil accounts for 0.4% ~ 0.6%) 65%
Menthol 0.1%
Tween 80 0.1%
Glycerol 1%
Distilled water surplus.
A preparation method for the healthcare collutory of galangal hydrolat, comprises the steps:
(1) preparation of galangal hydrolat: galangal hydrolat takes from the elite of fractional distillation in Rhizoma Alpiniae Officinarum quintessence oil distillation extraction process, the galangal plant material of fresh drying process is put into water steam to be extracted in fractionating device, water vapour is utilized to carry out by the stronger quintessence oil of volatilization, make it to form the vapor phase containing quintessence oil, recycling temp-difference condensing becomes liquid condition, thus isolate hydrosol water, whole still-process carries out in closed system;
(2) preparation of galangal hydrolat healthcare collutory: add galangal hydrolat after menthol, Tween 80, glycerol being mixed successively, stir, then add distilled water and stir, filtration sterilization, bottling, to obtain final product.
embodiment 3
. a kind of healthcare collutory of galangal hydrolat, is made up of the component of following weight portion:
Galangal hydrolat (volatile oil accounts for 0.4% ~ 0.6%) 45%
Menthol 1%
Tween 80 0.5%
Glycerol 2%
Distilled water surplus.
A preparation method for the healthcare collutory of galangal hydrolat, comprises the steps:
(1) preparation of galangal hydrolat: galangal hydrolat takes from the elite of fractional distillation in Rhizoma Alpiniae Officinarum quintessence oil distillation extraction process, the galangal plant material of fresh drying process is put into water steam to be extracted in fractionating device, water vapour is utilized to carry out by the stronger quintessence oil of volatilization, make it to form the vapor phase containing quintessence oil, recycling temp-difference condensing becomes liquid condition, thus isolate hydrosol water, whole still-process carries out in closed system;
(2) preparation of galangal hydrolat healthcare collutory: add galangal hydrolat after menthol, Tween 80, glycerol being mixed successively, stir, then add distilled water and stir, filtration sterilization, bottling, to obtain final product.
embodiment 4
A healthcare collutory for galangal hydrolat, is made up of the component of following weight portion:
Galangal hydrolat (volatile oil accounts for 0.4% ~ 0.6%) 55%
Menthol 2%
Tween 80 0.4%
Glycerol 4%
Distilled water surplus.
A preparation method for the healthcare collutory of galangal hydrolat, comprises the steps:
(1) preparation of galangal hydrolat: galangal hydrolat takes from the elite of fractional distillation in Rhizoma Alpiniae Officinarum quintessence oil distillation extraction process, the galangal plant material of fresh drying process is put into water steam to be extracted in fractionating device, water vapour is utilized to carry out by the stronger quintessence oil of volatilization, make it to form the vapor phase containing quintessence oil, recycling temp-difference condensing becomes liquid condition, thus isolate hydrosol water, whole still-process carries out in closed system;
(2) preparation of galangal hydrolat healthcare collutory: add galangal hydrolat after menthol, Tween 80, glycerol being mixed successively, stir, then add distilled water and stir, filtration sterilization, bottling, to obtain final product.
embodiment 5
A healthcare collutory for galangal hydrolat, is made up of the component of following weight portion:
Galangal hydrolat (volatile oil accounts for 0.4% ~ 0.6%) 60%
Menthol 1.5%
Tween 80 0.3%
Glycerol 3.5%
Distilled water surplus.
A preparation method for the healthcare collutory of galangal hydrolat, comprises the steps:
(1) preparation of galangal hydrolat: galangal hydrolat takes from the elite of fractional distillation in Rhizoma Alpiniae Officinarum quintessence oil distillation extraction process, the galangal plant material of fresh drying process is put into water steam to be extracted in fractionating device, water vapour is utilized to carry out by the stronger quintessence oil of volatilization, make it to form the vapor phase containing quintessence oil, recycling temp-difference condensing becomes liquid condition, thus isolate hydrosol water, whole still-process carries out in closed system;
(2) preparation of galangal hydrolat healthcare collutory: add galangal hydrolat after menthol, Tween 80, glycerol being mixed successively, stir, then add distilled water and stir, filtration sterilization, bottling, to obtain final product.
Claims (3)
1. a healthcare collutory for galangal hydrolat, is characterized in that: be made up of the component of following weight portion:
Galangal hydrolat 35-65%
Deodorant tune 0.1-2%
Cosolvent and antifreeze 0.1-0.5%
Wetting agent 1-5%
Distilled water surplus;
Described deodorant tune is menthol; Described cosolvent and antifreeze are Tween 80; Described wetting agent is glycerol.
2. the healthcare collutory of a kind of galangal hydrolat according to claim 1, is characterized in that: in described galangal hydrolat, volatile oil accounts for 0.4% ~ 0.6%.
3. for the preparation of a method for the healthcare collutory of galangal hydrolat according to claim 1, it is characterized in that: comprise the steps:
(1) preparation of galangal hydrolat: galangal hydrolat takes from the elite of fractional distillation in Rhizoma Alpiniae Officinarum quintessence oil distillation extraction process, the galangal plant material of fresh drying process is put into water steam to be extracted in fractionating device, water vapour is utilized to carry out by the stronger quintessence oil of volatilization, make it to form the vapor phase containing quintessence oil, recycling temp-difference condensing becomes liquid condition, thus isolate hydrosol water, whole still-process carries out in closed system;
(2) preparation of galangal hydrolat healthcare collutory: add galangal hydrolat after menthol, Tween 80, glycerol being mixed successively, stir, then add distilled water and stir, filtration sterilization, bottling, to obtain final product.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1973815A (en) * | 2006-12-04 | 2007-06-06 | 广东医学院 | Oral hygiene composition with galangal rhizome extract and its prepn process |
| CN102008399A (en) * | 2010-12-22 | 2011-04-13 | 韶关蓝威消毒药业有限公司 | Preparation method of antimicrobial mouthwash |
| CN103040682A (en) * | 2012-12-21 | 2013-04-17 | 苏州黑豆软件科技有限公司 | Sterilizing and pathogenic-fire reducing mouthwash and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1973815A (en) * | 2006-12-04 | 2007-06-06 | 广东医学院 | Oral hygiene composition with galangal rhizome extract and its prepn process |
| CN102008399A (en) * | 2010-12-22 | 2011-04-13 | 韶关蓝威消毒药业有限公司 | Preparation method of antimicrobial mouthwash |
| CN103040682A (en) * | 2012-12-21 | 2013-04-17 | 苏州黑豆软件科技有限公司 | Sterilizing and pathogenic-fire reducing mouthwash and preparation method thereof |
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