CN103731587A - Digital section scanning and positioning system - Google Patents
Digital section scanning and positioning system Download PDFInfo
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- CN103731587A CN103731587A CN201410008132.9A CN201410008132A CN103731587A CN 103731587 A CN103731587 A CN 103731587A CN 201410008132 A CN201410008132 A CN 201410008132A CN 103731587 A CN103731587 A CN 103731587A
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Abstract
The invention relates to a positioning system, discloses a digital section scanning and positioning system and aims at solving the problem that a traditional preview camera adopting a wide-angle lens causes edge distortion and accordingly causes deformation in the process from shooting and organization, and a converted platform coordinate is also inaccurate. The digital section scanning and positioning system comprises a scanning platform, a first image obtaining unit, a second image obtaining unit and a control system, wherein the control system is used for controlling the relative positions of the scanning platform and the first image obtaining unit or the relative positions of the scanning platform and the second image obtaining unit, the first image obtaining unit and the second image obtaining unit are placed above the scanning platform and face the scanning platform. The digital section scanning and positioning system is suitable for a scanner.
Description
Technical field
The present invention relates to a kind of navigation system, relate in particular to a kind of digital slices Scan orientation system.
Background technology
The process that traditional technology is carried out digital scan to pathological section is: first pathological section is placed on scanning platform, scanning platform is moved to (as shown in Figure 1) below preview camera 4, to whole section shooting preview figure, obtain the distribution situation of tissue; According to the preview graph of obtaining, (this region is referred to as ROI in the selected region that need to scan, as shown in Figure 2, D represents the preview graph photographing, E ' represents the ROI(Region Of Interest of identification, area-of-interest) region, C represents histotomy), then scanning platform is moved to carrying out fine scanning under the scanning camera of high power lens, obtain the high definition scan image in ROI region.But the high definition scan image that obtains ROI region whether accurately mainly depend on ROI pixel coordinate whether correct change into platform coordinate.Traditional preview camera 4 is owing to adopting wide-angle lens, bring marginal distortion, thereby cause photographing metaplasia, the section of identification Deformation structure, can obtain wrong ROI image, thereby the platform coordinate that transforms out by wrong ROI image is also wrong, according to this wrong platform coordinate, go scanning, scanning image is out not and the corresponding true picture in ROI region to have the problem of position error.
Summary of the invention
The object of the invention is to, digital slices Scan orientation system is provided, solve above technical problem.
Technical problem solved by the invention can realize by the following technical solutions:
Digital slices Scan orientation system of the present invention, comprising: scanning platform, the first image acquisition unit, the second image acquisition unit and control system,
Described control system is for controlling the relative position of described scanning platform and described the first image acquisition unit, or the relative position between described scanning platform and described the second image acquisition unit,
Described the first image acquisition unit and described the second image acquisition unit are positioned over described scanning platform top, and the first image acquisition unit and the second image acquisition unit are towards scanning platform.
In a preferred embodiment, the relative position relation of described scanning platform and the first image acquisition unit is as follows:
The vertical height of the distance of camera lens scanning platform of the first image acquisition unit is setting height H, and on described scanning platform, the line of optical center of cornerwise end points to the first image acquisition unit of area-of-interest and the angle of vertical direction are α, make:
α=L1/H；
L2=tanα*H，
In formula, L1 represents that radius is that H angle is the arc length of α, and L2 represents that an end points of described area-of-interest is to described cornerwise mid point distance.
In a preferred embodiment, described in the distance of camera lens of the camera lens of described the first image acquisition unit and described the second image acquisition unit, the vertical height of scanning platform is identical.
In a preferred embodiment, described scanning platform connects described control system, and described scanning platform is realized described scanning platform and move to from the view field of described the first image acquisition unit camera lens the view field of described the second image acquisition unit camera lens under the effect of described control system.
In a preferred embodiment, the camera lens that described the first image acquisition unit adopts is wide-angle lens.
In a preferred embodiment, described the second image acquisition unit adopts line camera.
What in a preferred embodiment, described the first image acquisition unit and described the second image acquisition unit were arranged side by side is placed horizontally at above described scanning platform.
In a preferred embodiment, described the first image acquisition unit carries ccd image sensor or cmos image sensor, and the resolution of described imageing sensor is 2,000,000 pixel to 1,000 ten thousand pixels.
Beneficial effect of the present invention:
The present invention is by setting the vertical height of the camera lens of the first image acquisition unit and the distance of camera lens scanning platform of the second image acquisition unit, and the angle of setting the first image acquisition unit optical center and the first image acquisition unit visual range, avoided bringing because of camera lens the impact of marginal distortion, reduce the error that image deformation brings, thereby finally obtain and the corresponding true picture in ROI region, reached registration and the complete object of scanning.
Accompanying drawing explanation
Fig. 1 adopts preview camera to take the overall schematic of section;
Fig. 2 is the section preview schematic diagram that preview camera photographs;
Fig. 3 is the front view of digital slices Scan orientation system of the present invention;
Fig. 4 is the vertical view of Fig. 3;
Fig. 5 is that the present invention adopts the first image acquisition unit to take the structural representation of section;
Fig. 6 adopts the present invention and conventional art to obtain the comparison diagram of ROI image.
Embodiment
Below in conjunction with the drawings and specific embodiments, the invention will be further described, but not as limiting to the invention.
Embodiment one, in conjunction with Fig. 3 to Fig. 5, illustrate present embodiment, present embodiment digital slices Scan orientation system, comprising: scanning platform 1, the first image acquisition unit 2, the second image acquisition unit 3 and control system,
Control system is for the relative position of gated sweep platform 1 and the first image acquisition unit 2, or the relative position between scanning platform 1 and the second image acquisition unit 3,
The first image acquisition unit 2 and the second image acquisition unit 3 are positioned over scanning platform 1 top, and the first image acquisition unit 2 and the second image acquisition unit 3 are towards scanning platform 1.
The difference of embodiment two, present embodiment and embodiment one digital slices Scan orientation system is, the relative position relation of scanning platform 1 and the first image acquisition unit 2 is as follows:
The vertical height of the distance of camera lens scanning platform 1 of the first image acquisition unit 2 is setting height H, and on scanning platform 1, the line of optical center of cornerwise end points to the first image acquisition unit 2 of area-of-interest and the angle of vertical direction are α, make:
α=L1/H；
L2=tanα*H，
In formula, L1 represents that radius is that H angle is the arc length of α, and L2 represents that an end points of area-of-interest is to cornerwise mid point distance.
The difference of embodiment three, present embodiment and embodiment one digital slices Scan orientation system is, the camera lens of the first image acquisition unit 2 is identical with the vertical height of the distance of camera lens scanning platform 1 of the second image acquisition unit 3.
The difference of embodiment four, present embodiment and embodiment one digital slices Scan orientation system is, scanning platform 1 connection control system, scanning platform 1 is realized scanning platform 1 and moves to from the view field of the first image acquisition unit 2 camera lenses the view field of the second image acquisition unit 3 camera lenses under the effect of control system.
The difference of embodiment five, present embodiment and embodiment one digital slices Scan orientation system is, the camera lens that the first image acquisition unit 2 adopts is wide-angle lens.
The difference of embodiment six, present embodiment and embodiment one digital slices Scan orientation system is, the second image acquisition unit 3 adopts line camera.
The difference of embodiment seven, present embodiment and embodiment one digital slices Scan orientation system is, the first image acquisition unit 2 and the second image acquisition unit 3 are arranged side by side is placed horizontally at scanning platform 1 top.
The difference of embodiment eight, present embodiment and embodiment one digital slices Scan orientation system is, the first image acquisition unit 2 carries ccd image sensor or cmos image sensor, and the resolution of imageing sensor is 2,000,000 pixel to 1,000 ten thousand pixels.
As shown in Figure 6, point centered by 0 in figure, OA ' and OB ' they are central point distance (pixel value) to the limit in preview graph, utilize α=L1/H and L2=tan α * H, can lead to and obtain OA, OA eliminates actual distance (pixel value) after distortion.In like manner can obtain OB according to OB ', by an A and some B, can obtain ROI region and eliminate after distortion, actual size (pixel value), the region E that dotted line on figure forms.The platform coordinate region converting by scheming E that upper dotted line forms, is real ROI region, makes scanning more accurate.
The foregoing is only preferred embodiment of the present invention; not thereby limit embodiments of the present invention and protection range; to those skilled in the art; the scheme that being equal to of should recognizing that all utilizations specification of the present invention and diagramatic content done replaces and apparent variation obtains, all should be included in protection scope of the present invention.
Claims (8)
1. digital slices Scan orientation system, is characterized in that, comprising: scanning platform (1), the first image acquisition unit (2), the second image acquisition unit (3) and control system,
Described control system is used for controlling the relative position of described scanning platform (1) and described the first image acquisition unit (2), or the relative position between described scanning platform (1) and described the second image acquisition unit (3),
Described the first image acquisition unit (2) is positioned over described scanning platform (1) top with described the second image acquisition unit (3), and the first image acquisition unit (2) and the second image acquisition unit (3) are towards scanning platform (1).
2. digital slices Scan orientation system as claimed in claim 1, is characterized in that, the relative position relation of described scanning platform (1) and the first image acquisition unit (2) is as follows:
The vertical height of the distance of camera lens scanning platform (1) of the first image acquisition unit (2) is setting height H, the line of optical center and the angle of vertical direction of cornerwise end points to the first image acquisition unit (2) of the upper area-of-interest of described scanning platform (1) are α, make:
α=L1/H；
L2=tanα*H，
In formula, L1 represents that radius is that H angle is the arc length of α, and L2 represents that an end points of described area-of-interest is to described cornerwise mid point distance.
3. digital slices Scan orientation system as claimed in claim 1, is characterized in that, the vertical height of scanning platform (1) is identical described in the distance of camera lens of the camera lens of described the first image acquisition unit (2) and described the second image acquisition unit (3).
4. digital slices Scan orientation system as claimed in claim 1, it is characterized in that, described scanning platform (1) connects described control system, and described scanning platform (1) is realized described scanning platform (1) and move to from the view field of described the first image acquisition unit (2) camera lens the view field of described the second image acquisition unit (3) camera lens under the effect of described control system.
5. digital slices Scan orientation system as claimed in claim 1, is characterized in that, the camera lens that described the first image acquisition unit (2) adopts is wide-angle lens.
6. digital slices Scan orientation system as claimed in claim 1, is characterized in that, described the second image acquisition unit (3) adopts line camera.
7. digital slices Scan orientation system as claimed in claim 1, is characterized in that, described the first image acquisition unit (2) and described the second image acquisition unit (3) are arranged side by side is placed horizontally at described scanning platform (1) top.
8. digital slices Scan orientation system as claimed in claim 1, is characterized in that, described the first image acquisition unit (2) carries ccd image sensor or cmos image sensor, and the resolution of described imageing sensor is 2,000,000 pixel to 1,000 ten thousand pixels.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410008132.9A CN103731587A (en) | 2013-12-18 | 2014-01-08 | Digital section scanning and positioning system |
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| CN201320842869.1 | 2013-12-18 | ||
| CN201320842869 | 2013-12-18 | ||
| CN201410008132.9A CN103731587A (en) | 2013-12-18 | 2014-01-08 | Digital section scanning and positioning system |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN200952996Y (en) * | 2006-09-07 | 2007-09-26 | 北京优纳科技有限公司 | Adaptive section scanning system |
| CN101408976A (en) * | 2007-10-11 | 2009-04-15 | 通用电气公司 | Enhanced system and method for volume based registration |
| CN102590155A (en) * | 2012-01-16 | 2012-07-18 | 华中科技大学 | Tissue slice scanning and imaging device |
| CN103399015A (en) * | 2013-08-14 | 2013-11-20 | 宁波江丰生物信息技术有限公司 | Pathological section scanner and method and device for measuring locating precision of slide glass platform |
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- 2014-01-08 CN CN201410008132.9A patent/CN103731587A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN200952996Y (en) * | 2006-09-07 | 2007-09-26 | 北京优纳科技有限公司 | Adaptive section scanning system |
| CN101408976A (en) * | 2007-10-11 | 2009-04-15 | 通用电气公司 | Enhanced system and method for volume based registration |
| CN102590155A (en) * | 2012-01-16 | 2012-07-18 | 华中科技大学 | Tissue slice scanning and imaging device |
| CN103399015A (en) * | 2013-08-14 | 2013-11-20 | 宁波江丰生物信息技术有限公司 | Pathological section scanner and method and device for measuring locating precision of slide glass platform |
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