CN103705727A - Chinese medicinal composition for treating diabetes - Google Patents

Chinese medicinal composition for treating diabetes Download PDF

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Publication number
CN103705727A
CN103705727A CN201410001198.5A CN201410001198A CN103705727A CN 103705727 A CN103705727 A CN 103705727A CN 201410001198 A CN201410001198 A CN 201410001198A CN 103705727 A CN103705727 A CN 103705727A
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radix
diabetes
chinese medicinal
medicinal composition
chinese medicine
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CN201410001198.5A
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王俊卿
周筱燕
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Abstract

The invention discloses a Chinese medicinal composition for treating diabetes. The Chinese medicinal composition is prepared from the following raw materials in percentage by weight: 2-8% of sun-cured ginseng, 10-16% of astragalus root, 3-9% of sweet potato, 6-12% of yam, 6-12% of prepared rhizome of rehmannia, 6-12% of lilyturf root, 10-16% of radices trichosanthis, 10-16% of dried rhizome of rehmannia, 2-8% of rhizoma anemarrhenae, 2-8% of amur cork tree bark and 10-16% of red sage root, wherein the total weight percentage of the components is 100%. According to the Chinese medicinal composition disclosed by the invention, the technical problems that an existing medicament has little treatment effect, can not treat both symptoms and root causes, is inexact in curative effect and has great toxic or side effect, resulting in that patients have strong dependence on the medicament and the medicament is not suitable for long-time taking, are solved.

Description

A kind of Chinese medicine composition for the treatment of diabetes
Technical field
The present invention relates to Chinese patent drug technique field, particularly a kind of Chinese medicine composition for the treatment of diabetes.
Background technology
Diabetes are harm humans life and healthy commonly encountered diseases and frequently-occurring disease, its sickness rate increases year by year, become international after tumor, the cardiovascular and cerebrovascular disease chronic disease of the 3rd serious harm human health of diabetes, the various diabetic complications that diabetes cause because of malpractice have become that diabetic is disabled and early dead main cause.Because diabetes not only cause great misery to patient's body and mind, and bring huge spirit and financial burden to society and family, so medical circle is more and more paid close attention to generation, development and prophylactico-therapeutic measures research to diabetes.
Below for the Study on Measures that prevents of diabetes is made progress:
More about the progress of diabetes medicament new drug very fast, exploitation in recent years, mainly contain six large class medicines and can supply selection of clinical, sulphanylureas, biguanides, alpha-glucosidase inhibitor, thiazolidinediones, insulin, Chinese medicine class.Because the toxic and side effects of Chinese medicine is less, and there is good advantage to delaying appearance and the complication of complication, more and more by vast clinical position person and patient, accepted.
The diabetes spp traditional Chinese medical science category of " quenching one's thirst ", its etiology and pathogenesis, ancient Chinese medicine doctor is discussed a lot of, head sees in < < and says through > > < < Ling Shu Miraculous Pivot or Divine Axis 〃 five change > > pieces of writing: " all soft weak person of the five internal organs; kind sick diseases due to endogenous heat of ZANG FU organs ", point out that the five internal organs weakness is the key factor of quenching one's thirst.< < faces disease guide case 〃 three types of diabetes > > to be pointed out: " three types of diabetes one card, though there is upper purgation to divide, does not get over hyperactivity of YANG due to deficiency of YIN in fact, and Tianjin is dried up hot excessive." known disease pathogenic characteristic deficiency of YIN be this, scorching is mark.With the passing of time this disease delays, deficiency of YIN affecting YANG, and visible impairment of both QI and YIN or deficiency in both YIN and YANG, disease enters network for a long time, yin asthenia generating intrinsic heat, the bright liquid in consumption Tianjin, forms congestion, is also the feature of Pathogenesis of Diabetes.
To sum up, although there are at present a lot of medicines available, obtainable having little effect, can not specimen part-time, and also uncertain therapeutic efficacy cuts, and toxic and side effects is large, patient is strong for the dependency of medicine, is unsuitable for long-term taking.
Summary of the invention
The object of the invention is to provide a kind of Chinese medicine composition for the treatment of diabetes, determined curative effect, and toxic and side effects is little, no dependence, long-term taking is safe and reliable.
The technical solution adopted in the present invention is: a kind of Chinese medicine composition for the treatment of diabetes, and the raw material weight percentage composition of making effective ingredient is: Radix Ginseng 2%-8%, Radix Astragali 10%-16%, Rhizoma Dioscoreae 3%-9%, Rhizoma Dioscoreae 6%-12%, Radix Rehmanniae Preparata 6%-12%, Radix Ophiopogonis 6%-12%, Radix Trichosanthis 10%-16%, Radix Rehmanniae 10%-16%, Rhizoma Anemarrhenae 2%-8%, Cortex Phellodendri 2%-8%, Radix Salviae Miltiorrhizae 10%-16%, the percentage by weight of above each component is 100%.
Further, the Chinese medicine composition of above-mentioned treatment diabetes, the raw material weight percentage ratio of making effective ingredient is: Radix Ginseng 5%, the Radix Astragali 13%, Rhizoma Dioscoreae 6%, Rhizoma Dioscoreae 9%, Radix Rehmanniae Preparata 9%, Radix Ophiopogonis 9%, Radix Trichosanthis 13%, the Radix Rehmanniae 13%, the Rhizoma Anemarrhenae 5%, Cortex Phellodendri 5%, Radix Salviae Miltiorrhizae 13%.
Further, the present invention also comprises the preparation method of the Chinese medicine composition for the treatment of diabetes, weighs the raw material of above-mentioned percentage by weight, after decoction, and the centrifugal filtration of removing slag, concentrated, autoclaving subpackage.
A kind of Chinese medicine composition for the treatment of diabetes disclosed by the invention, Selection and formula is rigorous, treating both the principal and secondary aspects of a disease, benefiting qi and nourishing yin promotes the production of body fluid, and heat clearing and blood circulation promoting blood stasis dispelling proves through Long-term Clinical Observation and lot of experiments, its curative effect certainly, can reduce blood glucose, can improve blood vessel, neural complication again, improves life in patients, reduce disability rate, and said composition is pure Chinese medicinal preparation, and toxic and side effects is little, can long-term taking, no dependence, safe and effective specimen is part-time.
The present invention treats the preparation method of the Chinese medicine composition of diabetes, and step is simple, easily implements process stabilizing.
The specific embodiment
A kind of Chinese medicine composition for the treatment of diabetes of the present invention, the raw material weight percentage ratio of making effective ingredient is: Radix Ginseng 2%-8%, Radix Astragali 10%-16%, Rhizoma Dioscoreae 3%-9%, Rhizoma Dioscoreae 6%-12%, Radix Rehmanniae Preparata 6%-12%, Radix Ophiopogonis 6%-12%, Radix Trichosanthis 10%-16%, Radix Rehmanniae 10%-16%, Rhizoma Anemarrhenae 2%-8%, Cortex Phellodendri 2%-8%, Radix Salviae Miltiorrhizae 10%-16%, the percentage by weight of above each component is 100%.
The present invention be take Radix Ginseng as monarch drug, supplementing QI for promoting the production of body fluid, be aided with the Radix Astragali, Rhizoma Dioscoreae with invigorating the spleen and benefiting QI, Rhizoma Dioscoreae, Radix Rehmanniae Preparata, Radix Ophiopogonis, replenishing kidney-YIN promoted the production of body fluid, Radix Trichosanthis, Radix Rehmanniae clearing away heat and promoting production of body fluid, the Rhizoma Anemarrhenae, Cortex Phellodendri heat clearing away, Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, full side's compatibility is rigorous, giving consideration to both the incidental and fundamental, supplementing QI for promoting the production of body fluid is to effect a permanent cure, and heat clearing and blood circulation promoting is to take stopgap measures.
For the effect of this compositions is clearly described, now each component is elaborated:
Radix Ginseng, claim again " Rhizoma Zingiberis Recens is sun-dried ", from ground, dig out to clean and dry, be " Radix Ginseng ", property sweet and slightly bitter taste, flat, return spleen lung heart channel, effect: strongly invigorating primordial QI, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, the increasing intelligence of calming the nerves, containing triterpene class Saponin and contain volatile oil (being mainly elemene, Radix Ginseng alkanol), cupreol and etc. glucoside, saccharide, several amino acids, liver alkali, enzyme, vitamin B1, B2, C etc.Modern study energy reducing blood glucose and and islets of langerhans have synergism.
The Radix Astragali, have another name called " continuous stilbene ", the sweet tepor of nature and flavor, return spleen lung meridian, effect: tonifying Qi and lifting yang, benefit is defended consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, diuretic moves back lung, containing saccharide, gallbladder alkali, folic acid, several aminoacid, cupreol, modern study has the effect that prevents that liver glycogen from reducing, separately also there is enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and more widely antibacterial action, and can eliminate Jishengshenqiwan albuminuria, strengthen myocardial contraction, regulate blood sugar content, can also coronary artery dilator, improve blood supply of cardiac muscle, improve immunologic function, process that can delaying cell aging.
Rhizoma Dioscoreae, claims again Radix Pachyrhizi Erosi, Radix Ipomoeae, sweet potato, Rhizoma Dioscoreae esculentae, Ipomoea batatas Lam., sweet potato etc., sweet, acid, temperature, returns liver, kidney channel, its liver and kidney tonifying, restrain astringent or styptic treatment for spontaneous sweating, containing vitamin A, Rhizoma Dioscoreae taro glycoside, Saponin, tannin, ursolic acid, malic acid, the acid of Mountain-spring stone.
Rhizoma Dioscoreae, sweet in the mouth, flat, returns lung, spleen, kidney channel, tonifying the spleen and stomach, lung benefiting kidney, mucous matter, Saponin, choline, arginine, amylase, starch, have the effect that tonify deficiency is won.
Radix Rehmanniae Preparata, sweet, tepor, GUIXIN Liver and kidney warp, the YIN nourishing of enriching blood, containing catalpol, rehmanin, retinoid material, saccharide and aminoacid.
Radix Ophiopogonis, sweet, micro-hardship, is slightly cold, GUIXIN lung stomach warp, yin nourishing stomach reinforcing, lung moistening clears away heart-fire, containing multiple steroidal, Saponin, phlegmatic temperament, etc. sugar, cupreol.
Radix Trichosanthis, hardship, micro-sweet, cold, return lung stomach warp, clearing away heat and promoting production of body fluid, detumescence and apocenosis, containing Saponin, protein and starch etc., be rich in the compositions such as several amino acids, vitamin A, vitamin C, vitamin E, active substance and trace element-selenium, phospholipid, nucleic acid.
The Radix Rehmanniae, another name Radix Rehmanniae, bitter in the mouth, micro-sweet, cold in nature, GUIXIN lung kidney channel, has clearing away heat and cooling blood, the effect of YIN nourishing and the production of body fluid promoting, containing rehmanin, mannitol, etc. sugar, irony, vitamin A etc.
The Rhizoma Anemarrhenae, bitter in the mouth, micro-sweet, cold in nature, returns lung stomach kidney channel, has clearing away heat-fire, and preventing phlegm from forming and stopping coughing is nourshing Yin and drynsessmoistening prescription, containing multiple steroid saponin, phlegmatic temperament.
Cortex Phellodendri, cold in nature, bitter in the mouth, returns kidney, bladder, large intestine channel, and clearing away damp-heat, lets out fire-toxin, reducing the asthenic fever, Han Ber, and have a small amount of palm leaf coculine, phellodendrine, the multiple alkaloid of palmatine, in addition, also have first nitrogen crystalline material and fatty oil, phlegmatic temperament, sterols etc.
Radix Salviae Miltiorrhizae, has another name called Radix Salviae Miltiorrhizae, Radix Salviae Miltiorrhizae, and Arisaema balansae Engl. etc., hardship, is slightly cold, GUIXIN, pericardium, Liver Channel, blood circulation promoting and blood stasis dispelling, removing heat from blood disappears bitterly, and relieving restlessness is calmed the nerves, containing TANSHINONES first, TANSHINONES second, TANSHINONES third, tanshinol Ⅰ, tanshinol II, vitamin E etc.
A kind of Chinese medicine composition for the treatment of diabetes of the present invention, preferred a kind of embodiment is: the raw material weight percentage ratio of making effective ingredient is: Radix Ginseng 5%, the Radix Astragali 13%, Rhizoma Dioscoreae 6%, Rhizoma Dioscoreae 9%, Radix Rehmanniae Preparata 9%, Radix Ophiopogonis 9%, Radix Trichosanthis 13%, the Radix Rehmanniae 13%, the Rhizoma Anemarrhenae 5%, Cortex Phellodendri 5%, Radix Salviae Miltiorrhizae 13%.
The present invention treats the preparation method of the Chinese medicine composition of diabetes: weigh the raw material of above-mentioned percentage by weight, and after decoction, the centrifugal filtration of removing slag, concentrated, autoclaving subpackage.Specifically comprise the steps:
Step 1, weighing medicine, take respectively Radix Ginseng 5% according to mass percent, the Radix Astragali 13%, Rhizoma Dioscoreae 6%, Rhizoma Dioscoreae 9%, Radix Rehmanniae Preparata 9%, Radix Ophiopogonis 9%, Radix Trichosanthis 13%, the Radix Rehmanniae 13%, the Rhizoma Anemarrhenae 5%, Cortex Phellodendri 5%, Radix Salviae Miltiorrhizae 13%;
Step 2, cleaning, medicine is cleaned the load weighted medicine removal of contamination of step 1;
Step 3, decoction, the medicine that step 2 is processed is put into drug weight 8-10 water doubly, is boiled into drug weight 1-3 liquid medicine doubly;
Step 4, the filtration of removing slag are distributed into the liquid medicine obtaining in step 3 in container after autoclaving.
This medicinal method is as follows:
Oral, adult every day 2 times, sooner or later bfore meals, each serving with containing aforementioned pharmaceutical compositions medicated powder weight 5-8 gram, light disease person is 5 grams, 8 grams of serious symptom persons.
Below for taking the case after this medicine:
Case 1, Lee, female, 70 years old, xerostomia polydipsia polyuria was weak, fasting glucose 9.8mmol/L, three after the meal 2 hours blood glucoses be respectively 11.5,12,10.1mmol/L, take this Chinese medicine composition after 3 weeks, without xerostomia polydipsia polyuria is weak, wait disease, survey fasting glucose 6.9mmol/L, three after the meal 2 hours blood glucoses be respectively 7.8,8,7.5mmol/L.
Case 2, money, man, 60 years old, diabetes 3 years, oral diamicron 80mg, 2 times/day of treatments, glycemic control is undesirable, fasting glucose 10-12mmol/L, conscious rapid digestion of food and polyorexia, becomes thin weak, large dry stool, add this Chinese medicine composition after January, without rapid digestion of food and polyorexia, stool is normal, weak alleviation, chemical examination fasting glucose 6.5mmol/L.
A kind of disclosed method of making the Chinese medicine composition for the treatment of diabetes of the present embodiment, Selection and formula is rigorous, and employing traditional handicraft, it has benefiting qi and nourishing yin and promotes the production of body fluid, the effect of heat clearing and blood circulation promoting blood stasis dispelling, through Long-term Clinical Observation and lot of experiments, prove, its curative effect certainly, can reduce blood glucose, can improve blood vessel, neural complication again, improves life in patients, reduce disability rate, and said composition is pure Chinese medicinal preparation, and toxic and side effects is little, can long-term taking, no dependence, safe and effective specimen is part-time.
Above; be only the specific embodiment of the present invention, but protection scope of the present invention is not limited to this, is anyly familiar with those skilled in the art in the technical scope that the present invention discloses; the variation that can expect easily or replacement, within all should being encompassed in protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion with the protection domain of claim.

Claims (3)

1. a Chinese medicine composition for the treatment of diabetes, is characterized in that, the raw material weight percentage ratio of making effective ingredient is: Radix Ginseng 2%-8%, Radix Astragali 10%-16%, Rhizoma Dioscoreae 3%-9%, Rhizoma Dioscoreae 6%-12%, Radix Rehmanniae Preparata 6%-12%, Radix Ophiopogonis 6%-12%, Radix Trichosanthis 10%-16%, Radix Rehmanniae 10%-16%, Rhizoma Anemarrhenae 2%-8%, Cortex Phellodendri 2%-8%, Radix Salviae Miltiorrhizae 10%-16%, the percentage by weight of above each component is 100%.
2. a kind of Chinese medicine composition for the treatment of diabetes according to claim 1, is characterized in that, the raw material weight percentage ratio of making effective ingredient is: Radix Ginseng 5%, the Radix Astragali 13%, Rhizoma Dioscoreae 6%, Rhizoma Dioscoreae 9%, Radix Rehmanniae Preparata 9%, Radix Ophiopogonis 9%, Radix Trichosanthis 13%, the Radix Rehmanniae 13%, the Rhizoma Anemarrhenae 5%, Cortex Phellodendri 5%, Radix Salviae Miltiorrhizae 13%.
3. a preparation method for the Chinese medicine composition of any treatment diabetes in claim 1-2, is characterized in that, weighs the raw material of above-mentioned percentage by weight, after decoction, and the centrifugal filtration of removing slag, concentrated, autoclaving subpackage.
CN201410001198.5A 2014-01-02 2014-01-02 Chinese medicinal composition for treating diabetes Pending CN103705727A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104306659A (en) * 2014-09-18 2015-01-28 张世龙 Traditional Chinese medicine composition for treating type 2 diabetes
CN108452160A (en) * 2018-07-02 2018-08-28 汝州市济仁糖尿病医院 A kind of ginseng stilbene Siberian cocklebur art preparation of breath in heptan training pancreas therapy treatment diabetes

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CN101612303A (en) * 2008-06-25 2009-12-30 王翠荣 Health-care medicinal liquor for treating diabetes
CN101972415A (en) * 2010-06-07 2011-02-16 中山市新运来医药科技开发有限公司 Traditional Chinese medicine-decocted soup or granule preparation for recuperating and treating diabetes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101612303A (en) * 2008-06-25 2009-12-30 王翠荣 Health-care medicinal liquor for treating diabetes
CN101972415A (en) * 2010-06-07 2011-02-16 中山市新运来医药科技开发有限公司 Traditional Chinese medicine-decocted soup or granule preparation for recuperating and treating diabetes

Non-Patent Citations (2)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104306659A (en) * 2014-09-18 2015-01-28 张世龙 Traditional Chinese medicine composition for treating type 2 diabetes
CN104306659B (en) * 2014-09-18 2017-07-14 张世龙 A kind of Chinese medicine composition for treating diabetes B
CN108452160A (en) * 2018-07-02 2018-08-28 汝州市济仁糖尿病医院 A kind of ginseng stilbene Siberian cocklebur art preparation of breath in heptan training pancreas therapy treatment diabetes

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Effective date of abandoning: 20170301