CN103688924A - Transplant cold protection bag - Google Patents
Transplant cold protection bag Download PDFInfo
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- CN103688924A CN103688924A CN201310723787.XA CN201310723787A CN103688924A CN 103688924 A CN103688924 A CN 103688924A CN 201310723787 A CN201310723787 A CN 201310723787A CN 103688924 A CN103688924 A CN 103688924A
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Abstract
The invention relates to a transplant cold protection bag which is formed by three layers of plastic composite films. A transplanted organ placement bag, a refrigerating bag and a heat insulation bag which are formed by middle films, are mutually closed and are provided with inner films are arranged in a wear-resistant plastic bag of an outer film; the transplant cold protection bag can be used for storing organ preservation solution, transplanted organs, a cool storage material and a heat insulation material which have temperatures of 0 to 4 DEG C; one end of the transplanted organ placement bag, together with the wear-resistant plastic bag, is provided with a transplanted organ taking and storing port formed by two magnets and a sealing material together; and the other end of the transplanted organ placement bag, together with the wear-resistant plastic bag, is provided with a liquid replacement tube with a blockage cap. The transplant cold protection bag disclosed by the invention ensures a low temperature of 0 to 4 DEG C, which is required by transplants in an operation and enables the transplants to have no warm ischemia time; the body temperature of a receptor is prevented from being reduced due to conduction of brine ice gauze and complications are reduced; and the transplants are convenient to move and a touch technology is not adopted. The transplant cold protection bag greatly improves the survival rate of postoperative organs and has important clinical significance and application prospect for storage of the transplants in the organ transplantation and vascular reconstruction process.
Description
Technical field
The present invention relates to a kind of Cooling protector of transplant organ, particularly relate to the cold protective bag of the graft of using in a kind of organ transfer operation.
Background technology
At present, dirty transplant operation, when carrying out vascular anastomosis, is all protected transplanted kidney with the Low-temperature Ice saline gauze of 0-4 ℃, and is placed it in acceptor body, to carry out easily transfer operation.In operation, in order to prevent the temperature of the hyperthermia brine ice gauze of acceptor, and then the transplant organ in the brine ice gauze that raise, make transplant organ occur warm ischemic phenomenon, transplant organ postoperative function is recovered to unfavorable, need constantly to change the brine ice gauze in acceptor or off and on gauze supplemented to brine ice, these two course of action one are to have increased operating time, have increased patient suffering and doctor's labour intensity; The 2nd, be still difficult to guarantee in whole anastomosis process, transplant internal organs official and in the low temperature of 0-4 ℃, occur warm ischemic phenomenon all the time everywhere; The 3rd, brine ice directly contact is subject to know from experience reduction acceptor body temperature, increases operation wound; The 4th, in operation can there is hand touch in mobile internal organs official unavoidably, and postoperative internal organs official's survival rate is exerted an influence; Larger brine ice gauze also can hinder operation in addition.
The object of the invention is the deficiency for conventional art; provide and a kind ofly might as well hinder operation; do not need to change brine ice gauze and gauze is supplemented to brine ice; the mutual non-conducting of temperature of the temperature of acceptor and the cold protective bag of graft; operation apoplexy involving the solid organs organ can not heat up all the time in the low temperature cold protective bag of 0-4 ℃; more can there is not hand and touch phenomenon, improve greatly the cold protective bag of graft of internal organs official survival rate after operation.
The object of the invention is to realize.The cold protective bag of graft of the present invention is characterised in that: the cold protective bag of described graft is by interior, in, outer three-layer plastic composite membrane forms, outer membrane is a Wear-resistant plastic pocket, described Wear-resistant plastic pocket inside is provided with each isolated transplant organ putting bag consisting of mesopelagic layer of mutual sealing from top to bottom, a refrigerating bag and an insulated bag, described transplant organ putting bag, refrigerating bag and insulated bag separately within it surface be fitted with one deck inner membrance, in the inner membrance of described transplant organ putting bag, deposit the organ preservative fluid of 0-4 ℃ of low temperature, in the inner membrance of described refrigerating bag, deposited cool storage material, in the inner membrance of described insulated bag, deposited heat-barrier material, one end of described transplant organ putting bag is got and is deposited mouth together with being jointly provided with a transplant organ on inner membrance and Wear-resistant plastic pocket, described transplant organ is got to deposit and mouthful two magnetics and the material of obturaging, is jointly consisted of, the other end of described transplant organ putting bag is together with being jointly provided with two displacement of the liquid with blocking cap pipes on inner membrance and Wear-resistant plastic pocket.
The cold protective bag of graft of the present invention, wherein said cool storage material is efficient agent for storage of coldness or for epoxy resin, described heat-barrier material 10 is silica gel or is heat conducting fiber not.
The cold protective bag of graft of the present invention, the cold protective bag of wherein said graft consists of plastic material co-extruded films under 100 grades of cleaning conditions of three layers of different melting points.
The cold protective bag of graft of the present invention, wherein said inner membrance is made by polypropylene or the polythene material of nontoxic and inertia; Transplant organ putting bag, refrigerating bag and insulated bag are made by polypropylene or polyamide material fine and close and that have a barrier property; Outer Wear-resistant plastic pocket is made by the large polypropylene of mechanical strength or polyamide material.
The cold protective bag of another kind of graft of the present invention, it is characterized in that: the cold protective bag of described graft is by a transplant organ putting bag, a refrigerating bag and an insulated bag constitute successively, described transplant organ putting bag, refrigerating bag and insulated bag separately within it surface be fitted with one deck inner membrance, in the inner membrance of described transplant organ putting bag, deposit the organ preservative fluid of 0-4 ℃ of low temperature, in the inner membrance of described refrigerating bag, deposited cool storage material, in the inner membrance 7 of described insulated bag, deposited heat-barrier material, one end of described transplant organ putting bag is jointly provided with a transplant organ together with inner membrance and gets and deposit mouth, described transplant organ is got to deposit and mouthful two magnetics and the material of obturaging, is jointly consisted of, the other end of described transplant organ putting bag is provided with two displacement of the liquid with blocking cap pipes jointly together with inner membrance.
The cold protective bag of graft of the present invention, wherein said transplant organ putting bag, refrigerating bag and insulated bag from top to bottom pass through the bonding formation of adhesives.
The cold protective bag difference from prior art of graft of the present invention is that the cold protective bag of graft of the present invention consists of interior, domestic and abroad three-layer plastic composite membrane.Outer membrane is a Wear-resistant plastic pocket, Wear-resistant plastic pocket inside be provided with film in formation mutual sealing and separately all with a transplant organ putting bag of inner membrance, a refrigerating bag and an insulated bag.In transplant organ putting bag, deposit the organ preservative fluid of 0-4 ℃ of low temperature, in refrigerating bag, deposited cool storage material, in insulated bag, deposited heat-barrier material.One end of transplant organ putting bag is jointly provided with a transplant organ jointly consisting of two magnetic materials and the material of obturaging together with inner membrance and Wear-resistant plastic pocket and gets and deposit mouth, and the other end is provided with two displacement of the liquids with blocking cap pipes jointly together with inner membrance and Wear-resistant plastic pocket.The cold protective bag beneficial effect of graft of the present invention is: 1. guaranteed the low temperature of 0-4 ℃ that the graft in reconstructing blood vessel process needs, made graft there is no warm Ischemia Time; 2. effectively prevent the decline of acceptor body temperature in vascular anastomosis process, improved the survival rate of acceptor, reduced postoperative complication.3. in vascular anastomosis, no touch technology during mobile graft conveniently also can guarantee to move, has improved the rear internal organs official survival rate of operation greatly.The preservation of the present invention graft when improving clinical organ transplant reconstructing blood vessel, has important clinical meaning and huge potential applicability in clinical practice.
Below in conjunction with accompanying drawing, the cold protective bag of graft of the present invention is described further.
Accompanying drawing explanation
Fig. 1 is that the solid of the cold protective bag of graft of the present invention is used view.
Fig. 2 is the main TV structure schematic diagram of the cold protective bag of graft of the present invention.
Fig. 3 is the plan structure schematic diagram of the transplant organ putting bag of the cold protective bag of graft of the present invention.
Fig. 4 is the plan structure schematic diagram of the refrigerating bag of the cold protective bag of graft of the present invention.
Fig. 5 is the plan structure schematic diagram of the insulated bag of the cold protective bag of graft of the present invention.
Embodiment
Fig. 1, Fig. 2, Fig. 3, Fig. 4, Fig. 5 have provided one embodiment of the present invention.As shown in Figure 1, Figure 2, shown in Fig. 3, Fig. 4, Fig. 5, the cold protective bag of graft of the present invention consists of interior, domestic and abroad three-layer plastic composite membrane, outer membrane is a Wear-resistant plastic pocket 1.Wear-resistant plastic pocket 1 inside is provided with each isolated transplant organ putting bag consisting of mesopelagic layer of mutual sealing 2, refrigerating bag 3 and an insulated bag 4 from top to bottom.Transplant organ putting bag 2, refrigerating bag 3 and insulated bag 4 separately within it surface be fitted with one deck inner layer film 5,6,7.In the inner membrance 5 of transplant organ putting bag 2, deposit the organ preservative fluid 8 of 0-4 ℃ of low temperature, in the inner membrance 6 of refrigerating bag 3, deposited cool storage material 9, in the inner membrance 7 of insulated bag 4, deposited heat-barrier material 10.One end of transplant organ putting bag 2 is got and is deposited mouth together with being jointly provided with a transplant organ on inner membrance 5 and Wear-resistant plastic pocket 1, and transplant organ is got to deposit and mouthful two magnetics 11 and the material of obturaging, jointly consisted of.The other end of transplant organ putting bag 2 is provided with two displacement of the liquid with blocking cap pipes 12 jointly together with inner membrance 5 and Wear-resistant plastic pocket 1.
The cold protective bag of graft of the present invention consists of plastic material co-extruded films under 100 grades of cleaning conditions of three layers of different melting points. Inner membrance 5,6,7 polypropylene by nontoxic and inertia or polythene material are made; Transplant organ putting bag 2, refrigerating bag 3 and insulated bag 4 are made by polypropylene or polyamide material fine and close and that have a barrier property; Outer Wear-resistant plastic pocket 1 is made by the large polypropylene of mechanical strength or polyamide material.Its cool storage material 9 is efficient agent for storage of coldness or for epoxy resin, and heat-barrier material 10 is silica gel or is heat conducting fiber not.
Fig. 1, Fig. 3, Fig. 4, Fig. 5 have provided another embodiment of the invention.As shown in Fig. 1, Fig. 3, Fig. 4, Fig. 5, the cold protective bag of graft is constituted successively by a transplant organ putting bag 2, a refrigerating bag 3 and an insulated bag 4.Transplant organ putting bag 2, refrigerating bag 3 and insulated bag 4 separately within it surface be fitted with one deck inner layer film 5,6,7.In the inner membrance 5 of transplant organ putting bag 2, deposit the organ preservative fluid 8 of 0-4 ℃ of low temperature, in the inner membrance 6 of refrigerating bag 3, deposited cool storage material 9, in the inner membrance 7 of insulated bag 4, deposited heat-barrier material 10.One end of transplant organ putting bag 2 is jointly provided with a transplant organ together with inner membrance 5 and gets and deposit mouth, and transplant organ is got to deposit and mouthful two magnetics 11 and the material of obturaging, jointly consisted of.The other end of transplant organ putting bag 2 is provided with two displacement of the liquid with blocking cap pipes 12 jointly together with inner membrance 5.
As shown in Figure 1, the cold protective bag of graft of the present invention, its transplant organ putting bag 2, refrigerating bag 3 and insulated bag 4 from top to bottom pass through the bonding formation of adhesives.
Transplant organ putting bag 2 contains the organ preservative fluid of 0-4 ℃, and during acceptor operation reconstructing blood vessel, transplant organ is placed wherein, in coincideing mobile graft convenient and can guarantee to move in to transplant organ no touch technology.The magnetic strip of paper used for sealing of one end is the gateway of transplant organ, and the liquid displacement pipe 12 of the other end can carry out dosing and change the operations such as liquid.Refrigerating bag 3 contains efficient agent for storage of coldness or epoxy resin, can make graft all the time in low temperature preservation state, almost there is no warm Ischemia Time (transplanted kidney supplies the time between recovery to blood after leaving cold preservation liquid), and the recovery of warm Ischemia Time homologous transplantation organ postoperative function is correlated with.Insulated bag 4 contains silica gel or non-heat conducting fiber heat insulation cold material.In operation, the insulated bag of the cold protective bag of graft 4 is placed on to the receptor site of operation patients, has effectively prevented the decline of acceptor body temperature in vascular anastomosis process, improved the survival rate of acceptor, reduced postoperative complication.
The outermost of the cold protective bag of graft is one deck wear-resistant plastic film, is provided with transplant organ and places pouch, refrigeration pouch, three pouches of the cold pouch of heat insulation in wear-resistant plastic film.The inside of each pouch is equipped with inner membrance 5,6,7.
The inert polymer that inner membrance 5,6,7 is totally nontoxic, stable chemical performance, does not come off or the foreign matter of degrading out, adopts polypropylene (PP), polyethylene (PE) to make in the present invention.
Transplant organ putting bag 2, refrigerating bag 3 and insulated bag 4 are fine and close nontoxic inert polymer, have good water, vapour lock separating performance, adopt polypropylene (PP), polyamide (PA) to make in the present invention.
Outer Wear-resistant plastic pocket 1 should have certain mechanical strength, adopts polypropylene (PP), polyamide (PA) to make in the present invention.
Above-described embodiment is described the preferred embodiment of the present invention; not scope of the present invention is limited; design under the prerequisite of spirit not departing from the present invention; various distortion and improvement that those of ordinary skills make technical scheme of the present invention, all should fall in the definite protection domain of the claims in the present invention book.
Claims (5)
1. the cold protective bag of graft, it is characterized in that: the cold protective bag of described graft is by interior, in, outer three-layer plastic composite membrane forms, outer membrane is a Wear-resistant plastic pocket (1), inner each the isolated transplant organ putting bag (2) being formed by mesopelagic layer of mutual sealing that is from top to bottom provided with of described Wear-resistant plastic pocket (1), a refrigerating bag (3) and an insulated bag (4), described transplant organ putting bag (2), refrigerating bag (3) and insulated bag (4) separately within it surface be fitted with one deck inner membrance (5, 6, 7), in the inner membrance (5) of described transplant organ putting bag (2), deposit the organ preservative fluid (8) of 0-4 ℃ of low temperature, in the inner membrance (6) of described refrigerating bag (3), deposited cool storage material (9), in the inner membrance (7) of described insulated bag (4), deposited heat-barrier material (10), one end of described transplant organ putting bag (2) is got and is deposited mouth together with being jointly provided with a transplant organ on inner membrance (5) and Wear-resistant plastic pocket (1), described transplant organ is got to deposit and mouthful two magnetics (11) and the material of obturaging, is jointly consisted of, the other end of described transplant organ putting bag (2) is together with being jointly provided with two displacement pipes of the liquid with blocking cap (12) on inner membrance (5) and Wear-resistant plastic pocket (1).
2. the cold protective bag of graft according to claim 1, is characterized in that: described cool storage material (9) is for efficient agent for storage of coldness or be epoxy resin, and described heat-barrier material (10) is silica gel or is heat conducting fiber not.
3. the cold protective bag of graft according to claim 1; it is characterized in that: the cold protective bag of described graft consists of plastic material co-extruded films under 100 grades of cleaning conditions of three layers of different melting points; described inner membrance (5,6,7) is made by polypropylene or the polythene material of nontoxic and inertia; transplant organ putting bag (2), refrigerating bag (3) and insulated bag (4) are made by polypropylene or polyamide material fine and close and that have a barrier property, and outer Wear-resistant plastic pocket (1) is made by the large polypropylene of mechanical strength or polyamide material.
4. the cold protective bag of graft, it is characterized in that: the cold protective bag of described graft is by a transplant organ putting bag (2), a refrigerating bag (3) and an insulated bag (4) constitute successively, described transplant organ putting bag (2), refrigerating bag (3) and insulated bag (4) separately within it surface be fitted with one deck inner membrance (5, 6, 7), in the inner membrance (5) of described transplant organ putting bag (2), deposit the organ preservative fluid (8) of 0-4 ℃ of low temperature, in the inner membrance (6) of described refrigerating bag (3), deposited cool storage material (9), in the inner membrance (7) of described insulated bag (4), deposited heat-barrier material (10), one end of described transplant organ putting bag (2) is got and is deposited mouth together with being jointly provided with a transplant organ on inner membrance (5), described transplant organ is got to deposit and mouthful two magnetics (11) and the material of obturaging, is jointly consisted of, the other end of described transplant organ putting bag (2) is together with being jointly provided with two displacement pipes of the liquid with blocking cap (12) on inner membrance (5).
5. the cold protective bag of graft according to claim 4, is characterized in that: described transplant organ putting bag (2), refrigerating bag (3) and insulated bag (4) from top to bottom pass through the bonding formation of adhesives.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310723787.XA CN103688924B (en) | 2013-12-24 | 2013-12-24 | Transplant cold protection bag |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310723787.XA CN103688924B (en) | 2013-12-24 | 2013-12-24 | Transplant cold protection bag |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103688924A true CN103688924A (en) | 2014-04-02 |
| CN103688924B CN103688924B (en) | 2015-07-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310723787.XA Expired - Fee Related CN103688924B (en) | 2013-12-24 | 2013-12-24 | Transplant cold protection bag |
Country Status (1)
| Country | Link |
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| CN (1) | CN103688924B (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3027591A1 (en) * | 2014-10-24 | 2016-04-29 | France N E I R | PACKAGING FOR TRANSPORTING A PORTION OF THE HUMAN OR ANIMAL BODY |
| CN107969419A (en) * | 2017-12-20 | 2018-05-01 | 中国人民解放军第二军医大学第二附属医院 | Low temperature protection renal bag and its application method are used in a kind of art |
| WO2018076567A1 (en) * | 2016-10-28 | 2018-05-03 | 中山大学附属第一医院 | Multi-organ preservation apparatus |
| JP2019094315A (en) * | 2017-11-28 | 2019-06-20 | 株式会社Ｓｃｒｅｅｎホールディングス | Organ housing vessel |
| CN110250164A (en) * | 2019-07-19 | 2019-09-20 | 上海长征医院 | A kind of low-temperature protection bag during liver transplant |
| CN114617118A (en) * | 2022-01-27 | 2022-06-14 | 范宁 | Internal organ transfer device |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021127718A1 (en) * | 2019-12-23 | 2021-07-01 | Organ Recovery Systems Pty Ltd | Intraoperative organ temperature regulation device |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1085081A1 (en) * | 1999-09-17 | 2001-03-21 | Laboratoires Genevrier | Method for the transport of cells and grafts |
| CN201345874Y (en) * | 2009-01-08 | 2009-11-18 | 孔佑华 | Medical cell tissue cryopreservation bag |
| CN202232704U (en) * | 2011-09-09 | 2012-05-30 | 明英姿 | Special specimen cold storage bag for transplanted kidney |
-
2013
- 2013-12-24 CN CN201310723787.XA patent/CN103688924B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1085081A1 (en) * | 1999-09-17 | 2001-03-21 | Laboratoires Genevrier | Method for the transport of cells and grafts |
| CN201345874Y (en) * | 2009-01-08 | 2009-11-18 | 孔佑华 | Medical cell tissue cryopreservation bag |
| CN202232704U (en) * | 2011-09-09 | 2012-05-30 | 明英姿 | Special specimen cold storage bag for transplanted kidney |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3027591A1 (en) * | 2014-10-24 | 2016-04-29 | France N E I R | PACKAGING FOR TRANSPORTING A PORTION OF THE HUMAN OR ANIMAL BODY |
| WO2018076567A1 (en) * | 2016-10-28 | 2018-05-03 | 中山大学附属第一医院 | Multi-organ preservation apparatus |
| JP2019094315A (en) * | 2017-11-28 | 2019-06-20 | 株式会社Ｓｃｒｅｅｎホールディングス | Organ housing vessel |
| CN111315215A (en) * | 2017-11-28 | 2020-06-19 | 株式会社斯库林集团 | Organ container |
| CN111315215B (en) * | 2017-11-28 | 2022-03-15 | 株式会社斯库林集团 | Organ container |
| US11459534B2 (en) | 2017-11-28 | 2022-10-04 | SCREEN Holdings Co., Ltd. | Organ container |
| CN107969419A (en) * | 2017-12-20 | 2018-05-01 | 中国人民解放军第二军医大学第二附属医院 | Low temperature protection renal bag and its application method are used in a kind of art |
| CN110250164A (en) * | 2019-07-19 | 2019-09-20 | 上海长征医院 | A kind of low-temperature protection bag during liver transplant |
| CN114617118A (en) * | 2022-01-27 | 2022-06-14 | 范宁 | Internal organ transfer device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103688924B (en) | 2015-07-22 |
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