CN103656349A - Traditional Chinese medicine complexing agent used for treatment of acne vulgaris - Google Patents
Traditional Chinese medicine complexing agent used for treatment of acne vulgaris Download PDFInfo
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- CN103656349A CN103656349A CN201310679819.0A CN201310679819A CN103656349A CN 103656349 A CN103656349 A CN 103656349A CN 201310679819 A CN201310679819 A CN 201310679819A CN 103656349 A CN103656349 A CN 103656349A
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Abstract
The invention discloses a traditional Chinese medicine complexing agent used for treatment of acne vulgaris. The traditional Chinese medicine complexing agent is characterized in that the traditional Chinese medicine complexing agent is prepared from the following medicinal materials in parts by weight: 8 parts of poria cocos, 14 parts of oriental wormwood, 10 parts of salvia miltiorrhiza, 9 parts of radix sophorae flavescentis, 14 parts of semen coicis, 6 parts of fructus aurantii, 11 parts of fructus forsythiae, 19 parts of dandelion, 14 parts of honeysuckle, 6 parts of orange jessamine roots, 9 parts of virginia creeper, 9 parts of radix angelicae and 4 parts of Alisma canaliculatum A. Br. etBouche. Preferably, the traditional Chinese medicine complexing agent further comprises 5 parts of setaria faberi and 6 parts of lysimachia japonica. Clinical experiments show that by selecting proper medicinal materials and proportion, the composite effects of effectively dispelling dampness and helping to acne prevention can be achieved, safety and effectiveness are achieved, and side effectrs are avoided.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine complex that is used for the treatment of acne.
Background technology
Acne is a kind of clinical common multiple pilosebaceous chronic inflammatory disease dermatoses, its pathogenic factors is complicated, main relevant with androgen levels rising, sebum secretion increase, pilosebaceous unit glandular tube hyperkeratosis, propionibacterium acnes and inflammation etc., be equivalent to " acne ", " rosacea caused by lung-wind ", " furuncle and prickly heat ", " whelk ", " pimples " of the traditional Chinese medical science etc.Because hindering face, make to suffer from patient's psychosomatic health and be affected, be discosmetic dermatosis.The patent medicine that cures mainly sorting verification according to its property of medicine, drug effect, function is treated.Conventional coptos bolus for clearing the upper heat, Fructus Gardeniae JINHUA ball, antiphlogistic forsythiae ball, fangfeng tongsheng pill, QINGRE ANCHUANG PIAN, TANSHINONES, XINHUANGPIAN, eliminating stagnation spirit, QINGKAILING etc.
In western medical treatment, adopt at present mostly erythromycin, chloromycetin, spironolactone, first nitre sound of crying or vomiting, the anti-inflammation such as minocycline is that principal agent thing or tretinoin medicines are treated, curative effect not significantly, easily recurrence, but some antibacterial-anti-inflammatory drug contains tetracycline, long-term taking can increase the weight of the burden of liver, kidney, easily causes toxic and side effects and anaphylaxis.Treatment by Chinese herbs, common drug has FUFANG ZHENZHU ANCHUANG PIAN, antiphlogistic forsythiae ball etc., but aspect cure rate, therapeutic effect, is being difficult to arrive satisfaction, in addition, although the cream of external frost can control inflammation, can make hair follicle, glandular tube more stop up, cause vicious cycle, so curative effect is not good enough.
At present, still do not have the effectively damp eliminating simultaneously again can be to the effective Chinese medicinal formulae of acne treatment.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine complex that is used for the treatment of acne, by selecting suitable medical material and proportioning thereof, reaches the composite efficacy that effectively damp eliminating can contribute to again acne control simultaneously.
In order to achieve the above object, the present invention by the following technical solutions: a kind of Chinese medicine complex that is used for the treatment of acne, is prepared from by the medical material of following weight proportion: 8 parts, Poria, 14 parts of Herba Artemisiae Scopariaes, 10 parts of Radix Salviae Miltiorrhizaes, 9 parts of Radix Sophorae Flavescentiss, 14 parts of Semen Coiciss, 6 parts of Fructus Aurantiis, 11 parts of Fructus Forsythiaes, 19 parts of Herba Taraxacis, 14 parts of Flos Loniceraes, 6 parts of Radix Murrayaes, 9 parts of Radix Parthenocissi Heterophyllaes, 9 parts of the Radixs Angelicae Dahuricae, 4 parts of Herba Alismatis Canaliculati.
Further, described medical material also comprises 5 parts of large herba setariae viridis grass, 6 parts of Herba Lysimachiae Cinerascentis.
According to theory of Chinese medical science: Shao Yangzhu important department, inside post fire mutually.If important department works well, mutually fiery catharsis rises and sends out degree of having, from the trouble without harmful climatic factors.If dysfunction of acting as a pivot, catharsis is not normal, and fire is difficult to keep position and reports life mutually, with the property of its wind wood, follow through on smoke face, cause the order acne of looking unfamiliar.The present invention is directed to the pathogeny of acne, the few sun of heat-clearing and toxic substances removing, catharsis of take is the rule for the treatment of, carries out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.The present invention is that selected medicament composing prescription, is clinical practice effective proved recipe of Acne treatment for many years under Traditional Chinese medical theory and clinical experience instruct, and the effective percentage of various acne is reached more than 97%, and short treating period, instant effect, have no side effect.Generally within 8-15 days, obvious effect can be seen, 2-3 the course for the treatment of, the effect of healing can be reached.
The pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
Poria [function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Herba Artemisiae Scopariae [function cures mainly] clearing away damp-heat, jaundice eliminating subcutaneous ulcer.For jaundice oliguria, eczema pruritus; Infectious jaundice type hepatitis.
Radix Salviae Miltiorrhizae [function cures mainly] stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Radix Sophorae Flavescentis [function cures mainly] heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.
Semen Coicis [function cures mainly] spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, row is dense in heat clearing away.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.
Fructus Aurantii [function cures mainly] regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, sub-official's prolapsus.
Fructus Forsythiae [function cures mainly] heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease is from the beginning of, warm joining the army, high hot excessive thirst, coma is sent out speckle, pyretic stranguria urine retention.
Herba Taraxaci [function cures mainly] heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Flos Lonicerae [function cures mainly] heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease heating.
Radix Murrayae [nature and flavor] sweetness and bitterness, temperature.[function cures mainly] wind-damp dispelling, promoting the circulation of blood gas.Control traumatic injury, rheumatic ostalgia, heart peratodynia.
Radix Parthenocissi Heterophyllae [nature and flavor] hardship, temperature.[function cures mainly] expelling wind and removing dampness, dredging collateral, hemostasis, removing toxic substances.Dispelling the wind and dampness pathogens arthralgia pain, migraine, rheumatism sore, fracture.
The loose wind dehumidifying of the Radix Angelicae Dahuricae [function cures mainly], understand things pain-stopping, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.
Herba Alismatis Canaliculati [nature and flavor] is light, micro-pungent, flat.[function cures mainly] heat clearing away, removing toxic substances.Cure mainly skin bleb, urinary obstruction, edema, venom etc.
Large herba setariae viridis grass [nature and flavor] is sweet, flat.[function cures mainly] heat clearing away infantile malnutrition that disappears, killing parasites for relieving itching.For infantile malnutrition, rubella, toothache due to dental caries.
Herba Lysimachiae Cinerascentis [nature and flavor] acid, bitter, cool.[function cures mainly] stops blooding antipyretic, vital energy regualting and blood circulation-promoting, and the detumescence of drawing out pus by applying a plaster to the affected part, arresting convulsion is only jerked.Cure mainly traumatic injury, innominate toxic swelling, injury by sword or axe.
The invention has the beneficial effects as follows: the present invention all adopts natural raw material of Chinese medicine, its prescriptions principle that preparation is easy, medicine source is wide, cost is low, it follows the traditional Chinese medical science, various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy, reliable effect, and the property of medicine is gentle, does not occur toxic and side effects, can effectively cure acne, makes to be again difficult for recurrence, has made up simple by the not good enough and easy drawback of outbreak repeatedly of western medicine effect.Effective percentage reaches 96.5%, and cure rate reaches more than 77.9%.
Below in conjunction with clinical trial and model case thereof, further illustrate:
1, physical data
Be selected from and accept outpatient's totally 172 examples, male's 95 examples, women's 77 examples year November in January, 2008 to 2013 for medical treatment; 18-42 years old age, the course of disease 30 days-2 years.Severity Scaling: I level (slightly): 58 examples; II level (moderate): patient's 42 examples; III level (moderate): patient's 38 examples; IV level (severe): 34 examples.Be divided at random treatment group, matched group.Difference that under two groups of patient ages, sex, the course of disease, the clinical manifestation order of severity and colonoscopes there are no significant degree of inflammation and scope aspect, has comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group makes according to specific embodiment 1, sooner or later respectively once.3 weeks courses for the treatment of.
2.2 matched group oral tetracycline (teracycline) 0.25g, once a day.3 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Cure: skin lesion all disappears, and only leaves pigmentation or cicatrix; Effective: skin lesion disappears more than 70%, or order of severity degradation is more than 2 grades; Effective: the skin lesion focus 30-70% that disappears, or the order of severity subtracts level more than 1 grade, do not have new skin lesion to occur; Invalid: skin lesion focus disappears below 30% or slightly increases the weight of.
3.2 treatment statistical results are in Table 1.
Table 1 liang group curative effect comparison
| Group | n | Cure | Effective | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 86 | 67（77.9%） | 9（10.5%） | 7（8.1%) | 3（3.5%） | 96.5% |
| Matched group | 86 | 48（55.8%） | 10（11.6%） | 12（13.9%） | 16（18.6%） | 81.4% |
Visible, the medicine that the present invention makes can safe and effective Acne treatment.
The specific embodiment
In order to understand better and to implement the present invention, below in conjunction with specific embodiment, further illustrate the present invention.
Embodiment 1
Take: 8 grams, Poria, 14 grams of Herba Artemisiae Scopariaes, 10 grams of Radix Salviae Miltiorrhizaes, 9 grams of Radix Sophorae Flavescentiss, 14 grams of Semen Coiciss, 6 grams of Fructus Aurantiis, 11 grams of Fructus Forsythiaes, 19 grams of Herba Taraxacis, 14 grams of Flos Loniceraes, 6 grams of Radix Murrayaes, 9 grams of Radix Parthenocissi Heterophyllaes, 9 grams of the Radixs Angelicae Dahuricae, 4 grams of Herba Alismatis Canaliculati, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merge filtrate twice, concentrated, incapsulate shell.
Morning and evening for oral administration respectively once.
Embodiment 2
Take: 8 grams, Poria, 14 grams of Herba Artemisiae Scopariaes, 10 grams of Radix Salviae Miltiorrhizaes, 9 grams of Radix Sophorae Flavescentiss, 14 grams of Semen Coiciss, 6 grams of Fructus Aurantiis, 11 grams of Fructus Forsythiaes, 19 grams of Herba Taraxacis, 14 grams of Flos Loniceraes, 6 grams of Radix Murrayaes, 9 grams of Radix Parthenocissi Heterophyllaes, 9 grams of the Radixs Angelicae Dahuricae, 4 grams of Herba Alismatis Canaliculati, 5 grams of large herba setariae viridis grass, 6 grams of Herba Lysimachiae Cinerascentis, add 8 times of water gagings, decocts 1.5 hours, filters; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merge filtrate twice, concentrated, incapsulate shell.
Morning and evening for oral administration respectively once.
Obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give all embodiments exhaustive.Every still row in protection scope of the present invention of apparent variation that technical scheme of the present invention extends out or change that belong to.
Claims (2)
1. a Chinese medicine complex that is used for the treatment of acne, is characterized in that, is prepared from: 8 parts, Poria by the medical material of following weight proportion, 14 parts of Herba Artemisiae Scopariaes, 10 parts of Radix Salviae Miltiorrhizaes, 9 parts of Radix Sophorae Flavescentiss, 14 parts of Semen Coiciss, 6 parts of Fructus Aurantiis, 11 parts of Fructus Forsythiaes, 19 parts of Herba Taraxacis, 14 parts of Flos Loniceraes, 6 parts of Radix Murrayaes, 9 parts of Radix Parthenocissi Heterophyllaes, 9 parts of the Radixs Angelicae Dahuricae, 4 parts of Herba Alismatis Canaliculati.
2. a kind of Chinese medicine complex that is used for the treatment of acne according to claim 1, is characterized in that, described medical material also comprises 5 parts of large herba setariae viridis grass, 6 parts of Herba Lysimachiae Cinerascentis.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103976914A (en) * | 2014-05-30 | 2014-08-13 | 广州丹奇日用化工厂有限公司 | China creeper root extracting solution as well as preparation method and application thereof |
Citations (2)
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| CN1351872A (en) * | 2000-11-10 | 2002-06-05 | 张志宏 | Chinese herbal medicine for curing comedo and acne |
| KR20070115507A (en) * | 2006-06-02 | 2007-12-06 | 주식회사 에스티씨나라 | Skin topical composition comprising iris germanica, centella asiatica urbain, matricaria chamomilia, oenothera odorate jacq. and houttuynia cordata thunb. for improvement of a pimpled skin |
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2013
- 2013-12-15 CN CN201310679819.0A patent/CN103656349A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1351872A (en) * | 2000-11-10 | 2002-06-05 | 张志宏 | Chinese herbal medicine for curing comedo and acne |
| KR20070115507A (en) * | 2006-06-02 | 2007-12-06 | 주식회사 에스티씨나라 | Skin topical composition comprising iris germanica, centella asiatica urbain, matricaria chamomilia, oenothera odorate jacq. and houttuynia cordata thunb. for improvement of a pimpled skin |
Non-Patent Citations (2)
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| 李志顺等: "清热燥湿法治疗痤疮50例", 《山西中医》 * |
| 赵金辉等: "中医治疗痤疮150例临床观察", 《中医药信息》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103976914A (en) * | 2014-05-30 | 2014-08-13 | 广州丹奇日用化工厂有限公司 | China creeper root extracting solution as well as preparation method and application thereof |
| CN103976914B (en) * | 2014-05-30 | 2016-08-31 | 广州丹奇日用化工厂有限公司 | A kind of Radix Parthenocissi Heterophyllae extracting solution and its preparation method and application |
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