Summary of the invention
Goal of the invention: in order to address the above problem, the object of the present invention is to provide a kind of Chinese medicine hand cream and preparation method thereof.
Technical scheme: the object of the invention is to realize by following scheme:
A Chinese medicine hand cream, is comprised of sodium polyoxyethelene lauryl alcohol sulfate 15-30 part, isooctadecanol 12-18 part, isopropyl myristate 6-10 part, Herba Centipedae 2-4 part, Herba Pyrolae 2-4 part.
The preparation method of above-mentioned Chinese medicine hand cream, preparation process is: get Herba Centipedae, Herba Pyrolae, decoct with water twice, the 8-12 that adds for the first time water and be medical material weight doubly measures, and decocts 1-2h, the 6-10 that adds for the second time water and be medical material weight doubly measures, decoct 1-2h collecting decoction, while being concentrated into 65 ℃, relative density is 1.10-1.20, adds sodium polyoxyethelene lauryl alcohol sulfate, isooctadecanol, isopropyl myristate, 70-80 ℃ of left and right is melt and dissolved, obtains.
The application of above-mentioned Chinese medicine hand cream in preparing Chinese medicine hand cream.
Beneficial effect: Herba Centipedae wind dispelling cold expelling in the present invention, Herba Pyrolae dephlogistication and promoting nuscle growth, both compatibilities, promote that skin keratin degradation property is good after being prepared into Chinese medicine hand cream, make the attenuation of cuticular layer thickness, slow down aging.
Test one, the impact of the present invention on rabbit Keratoderma layer thickness
1, instrument and reagent Chinese medicine hand cream of the present invention: press embodiment 3 method preparations.
2, experimental animal rabbit, body weight 1.8-2kg, male and female dual-purpose, clean level.By Shanghai Slac Experimental Animal Co., Ltd., provided production licence: SCXK (Shanghai) 2007-0005.
3, rabbit is 10, and the numbering of weighing is divided into two groups at random, be respectively normal saline group and of the present invention group, at back and ear, smear normal saline and the present invention respectively, administration is after 40 days, and two groups of administrations place are drawn materials, fixing, dehydration according to a conventional method, embedding, section, HE dyeing, optical microphotograph Microscopic observation is respectively organized cuticular layer thickness, and compares, and found that the present invention makes the attenuation of cuticular layer thickness, promote cutin degraded, slow down aging.
The present invention is on the impact of rabbit Keratoderma layer thickness (χ ± s, n=5)
Note: compare with normal saline group
*p<0.05
*<0.01
The specific embodiment
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as to the scope of the above-mentioned theme of the present invention only limits to following example, all technology realizing based on foregoing of the present invention all belong to scope of the present invention.
Embodiment 1
Get each 2 parts of Herba Centipedae, Herba Pyrolaes, decoct with water twice, adding for the first time water is 8 times of amounts of medical material weight, decocts 1h, and adding for the second time water is 6 times of amounts of medical material weight, decoct 1h, collecting decoction, while being concentrated into 65 ℃, relative density is 1.10, adds sodium polyoxyethelene lauryl alcohol sulfate 15-part, 12 parts of isooctadecanols, 6 parts of isopropyl myristates, 70 ℃ melt and dissolved, obtains.
Embodiment 2
Get each 4 parts of Herba Centipedae, Herba Pyrolaes, decoct with water twice, adding for the first time water is 12 times of amounts of medical material weight, decocts 2h, and adding for the second time water is 10 times of amounts of medical material weight, decoct 2h, collecting decoction, while being concentrated into 65 ℃, relative density is 1.20, adds 30 parts of sodium polyoxyethelene lauryl alcohol sulfates, 18 parts of isooctadecanols, 10 parts of isopropyl myristates, 80 ℃ of left and right are melt and dissolved, obtain.
Embodiment 3
Get each 3 parts of Herba Centipedae, Herba Pyrolaes, decoct with water twice, adding for the first time water is 10 times of amounts of medical material weight, decoct 1.5h, adding for the second time water is 8 times of amounts of medical material weight, decocts 1.5h collecting decoction, while being concentrated into 65 ℃, relative density is 1.15, add 25 parts of sodium polyoxyethelene lauryl alcohol sulfates, 15 parts of isooctadecanols, 8 parts of isopropyl myristates, 75 ℃ melt and dissolved, obtains.
In above-mentioned Chinese medicine, Herba Centipedae is the wounded in the battle herb of dicotyledon medicine feverfew Myriogyne minuta.Herba Pyrolae is the herb of Pyrolaceae plant Herba pyrolae japonicae.