CN103630506B - Detection module and detection device - Google Patents
Detection module and detection device Download PDFInfo
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- CN103630506B CN103630506B CN201310365671.3A CN201310365671A CN103630506B CN 103630506 B CN103630506 B CN 103630506B CN 201310365671 A CN201310365671 A CN 201310365671A CN 103630506 B CN103630506 B CN 103630506B
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- 238000001514 detection method Methods 0.000 title abstract 8
- 230000003287 optical effect Effects 0.000 claims abstract description 112
- 238000005538 encapsulation Methods 0.000 claims description 30
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 21
- 229910052760 oxygen Inorganic materials 0.000 claims description 21
- 239000001301 oxygen Substances 0.000 claims description 21
- 239000008280 blood Substances 0.000 claims description 18
- 210000004369 blood Anatomy 0.000 claims description 17
- 239000000463 material Substances 0.000 claims description 10
- 230000009466 transformation Effects 0.000 claims description 9
- 230000005540 biological transmission Effects 0.000 abstract description 3
- 238000004806 packaging method and process Methods 0.000 abstract 3
- INGWEZCOABYORO-UHFFFAOYSA-N 2-(furan-2-yl)-7-methyl-1h-1,8-naphthyridin-4-one Chemical compound N=1C2=NC(C)=CC=C2C(O)=CC=1C1=CC=CO1 INGWEZCOABYORO-UHFFFAOYSA-N 0.000 description 9
- 108010002255 deoxyhemoglobin Proteins 0.000 description 9
- 239000011295 pitch Substances 0.000 description 7
- 238000002835 absorbance Methods 0.000 description 5
- 239000012141 concentrate Substances 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 3
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 3
- 239000010931 gold Substances 0.000 description 3
- 229910052737 gold Inorganic materials 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 208000035473 Communicable disease Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 108010064719 Oxyhemoglobins Proteins 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000000862 absorption spectrum Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14552—Details of sensors specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
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- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Heart & Thoracic Surgery (AREA)
- Optics & Photonics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
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- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The invention provides a detection device for detecting physiological parameters of biological tissues. The detection device comprises at least one detection module. In the detection module, the light source unit is used for emitting a first light beam and a second light beam, wherein the wavelength of the first light beam is different from that of the second light beam. The packaging unit is arranged on the light source unit and the light detection unit and is positioned on a transmission path of the first light beam and the second light beam from the light source unit. The optical microstructure unit is configured on a transmission path of the first light beam and the second light beam, wherein the first light beam and the second light beam emitted by the light source unit sequentially pass through the packaging unit, pass through the optical microstructure unit, are transmitted to biological tissues, pass through the optical microstructure unit, pass through the packaging unit and are transmitted to the light detection unit.
Description
Technical field
The invention relates to a kind of detecting module and detector.
Background technology
Along with the progress of photoelectric technology, utilize various optical principle to measure the physiological parameter of biology or human body instrument or
Device is gradually developed.Optical principle is measured technology and be can be usually reached the measurement of non-intrusion type, at medical science or biological field
In can effectively prevent to infect or infectious disease, therefore in medical science or biological field, have important contribution and using value.
General existing reflective blood oxygen concentration meter, is to utilize infrared light and near infrared light are squeezed into human body, then measures
The optical signal returned, and by signal processor, to compare band oxygen haemachrome (oXyhemoglobin, HbO2) blood red with deoxidation
Element (deoXyhemoglobin, Hb) absorption ratio to infrared light Yu near infrared light, and then calculate saturated blood oxygen concentration.Blood
The main element of oxymeter has for transmitting and receive optical signal at two: one, and the optical signal of reception is converted into signal of telecommunication hardware
Measurement apparatus, another part is then with display hardware and the internal software calculating blood oxygen numerical value function.Owing to measuring dress
Putting to typically require and be contacted with human body surface, this can produce noise because of the action of human body or body physiological changed condition often, because of
This is readily obtained the blood oxygen concentration readings of mistake.So, generally need to develop software to blood oxygen concentration meter of arranging in pairs or groups, make an uproar filtering this
Sound, and then guarantee the accuracy of the numerical value read.
Summary of the invention
A kind of detector of one embodiment of the invention is in order to detect the physiological parameter of biological tissue.Detector includes
At least one detecting module, and detecting module includes light source cell, light detecting unit, encapsulation unit and optical microstructures unit.Light
Source unit is in order to send the first light beam and the second light beam, and wherein the wavelength of the first light beam is different from the wavelength of the second light beam.Encapsulation
Cell location is on light source cell with light detecting unit, and is positioned at the first light beam from light source cell and the transmission of the second light beam
On path.Optical microstructures cell location is on the bang path of the first light beam and the second light beam, and wherein light source cell is sent
The first light beam and the second light beam pass sequentially through encapsulation unit, by optical microstructures unit, be transferred to biological tissue, pass through light
Learn microstructure unit, by encapsulation unit and be transferred to light detecting unit.
For the features described above of the present invention can be become apparent, special embodiment below, and coordinate appended accompanying drawing to make in detail
It is described as follows.
Accompanying drawing explanation
Figure 1A is the schematic top plan view of the detector of one embodiment of the invention.
Figure 1B is the detector generalized section along I-I line of Figure 1A.
Fig. 1 C is the detector generalized section along II-II line of Figure 1A.
Fig. 2 is the band oxygen haemachrome abosrption spectrogram with deoxy-hemoglobin of the mankind.
Fig. 3 A is the schematic top plan view of the detector of another embodiment of the present invention.
Fig. 3 B is the detector generalized section along III-III line of Fig. 3 A.
Fig. 3 C is the detector generalized section along IVIV line of Fig. 3 A.
Fig. 4 A and Fig. 4 B is the generalized section of the detector of another embodiment of the present invention.
Fig. 5 A to Fig. 5 C is the schematic top plan view of the detector of other three embodiments of the present invention.
Main element symbol description
| Biological tissue | 50 |
| Detector | 100、100a、100b、100c、100d、100e |
| Computing unit | 110 |
| Connect sheet | 120、120e |
| Detecting module | 200、200a、200b |
| Light source cell | 210、210a |
| First light-emitting component | 212 |
| Light-emitting area | 213 |
| Part I | 2131 |
| Part II | 2132 |
| Second light-emitting component | 214 |
| Material for transformation of wave length | 216a |
| Light detecting unit | 220、220a |
| First optical detector | 220a |
| Second optical detector | 224a |
| Encapsulation unit | 230 |
| First wave guide | 232 |
| Second waveguide | 234 |
| Optical microstructures unit | 240、240a、240b |
| First optical microstructures | 242a |
| Second optical microstructures | 244a |
| Light separating element | 250 |
| Outer housing | 260 |
| Original beam | B0 |
| First light beam | B1 |
| Second light beam | B2 |
| The signal of telecommunication | E、E1、E2 |
| Spacing | G |
Following detailed description of the invention will further illustrate the present invention in conjunction with above-mentioned accompanying drawing.
Detailed description of the invention
Figure 1A is the schematic top plan view of the detector of one embodiment of the invention, Figure 1B be Figure 1A detector along
The generalized section of I-I line, and the detector that Fig. 1 C is Figure 1A is along the generalized section of II-II line.Refer to Figure 1A extremely
Fig. 1 C, detector 100 friend of the present embodiment is to detect the physiological parameter of biological tissue 50.For example, biological tissue 50 example
Such as the skin for the mankind or animal, and above-mentioned physiological parameter for example, blood oxygen concentration.Detector 100 includes at least one detecting mould
Block 200 (being in the present embodiment as a example by including a detecting module 200), and detecting module 200 include light source cell 210,
Light detecting unit 220, encapsulation unit 230 and optical microstructures unit 240.Light source cell 210 in order to send the first light beam B1 (as
Depicted in Figure 1B) and the second light beam B2 (as depicted in Fig. 1 C), wherein the wavelength of the first light beam B1 is different from the second light beam B2's
Wavelength.In the present embodiment, the wavelength of the first light beam B1 and the second light beam B2 falls in the HONGGUANG wave-length coverage with infrared light.Lift
For example, the first light beam B1 is HONGGUANG, its wavelength for example, 660 nanometer；Second light beam B2 is infrared light, and its wavelength is for example,
910 nanometers.Or, in another embodiment, it is also possible to the first light beam B1 is infrared light, and the second light beam B2 is HONGGUANG.Additionally,
In other embodiments, the first light beam B1 and the second light beam B2 can also be the ripple at other visible rays or other black lights that falls
In long scope.
In the present embodiment, light source cell 210 includes the first light-emitting component 212 and the second light-emitting component 214.First is luminous
Element 212 is in order to send the first light beam B1, and the second light-emitting component 214 is in order to send the second light beam B2.In the present embodiment,
One light-emitting component 212 and the second light-emitting component 214 send the first light beam B1 and the second light beam B2 in turn.In the present embodiment, light
Source unit 210 includes light emitting diode (light-emitting diode), and namely the first light-emitting component 212 and second is luminous
Element 214 for example, light emitting diode.But, in other embodiments, the first light-emitting component 212 and the second light-emitting component 214
Can also be Organic Light Emitting Diode (organic light-emitting diode, OLED) or laser diode (laser
diode).Additionally, in the present embodiment, light detecting unit 220 is optical detector, for example, photodiode
(photodiode)。
Encapsulation unit 230 is configured on light source cell 210 and light detecting unit 220, and is positioned at from light source cell 210
On the bang path of the first light beam B1 and the second light beam B2.In the present embodiment, encapsulation unit 230 be suitable to by the first light beam B1 with
Second light beam B2 penetrates.For example, in the present embodiment, encapsulation unit 230 is suitable to be penetrated by infrared light and HONGGUANG.But,
In other embodiments, encapsulation unit 230 can also be penetrated with visible ray by infrared light.Additionally, in the present embodiment, encapsulation is single
Unit 230 includes waveguide (waveguide), and it covers light source cell 210 and light detecting unit 220.Specifically, at the present embodiment
In, encapsulation unit 230 includes first wave guide 232 and second waveguide 234, and first wave guide 232 covers light source cell 210, and second
Waveguide 234 covers light detecting unit 220.
Optical microstructures unit 240 is configured on the bang path of the first light beam B1 and the second light beam B2, wherein light source list
The first light beam B1 of being sent of unit 210 and the second light beam B2 pass sequentially through encapsulation unit 230, by optical microstructures unit 240,
It is transferred to biological tissue 50, by optical microstructures unit 240, by encapsulation unit 230 and be transferred to light detecting unit 220.
In the present embodiment, optical microstructures unit 240 is diffraction optical element (diffractive optical element, DOE)
Structure.Additionally, in the present embodiment, optical microstructures unit 240 is the surface micro-structure of encapsulation unit 230.But, at another
In embodiment, optical microstructures unit 240 can be blooming piece, and optical microstructures unit 240 is located at encapsulation unit 230
On, e.g. attach or be bearing on encapsulation unit 230.In other words, optical microstructures unit 240 can also be to attach or hold
It is against the diffraction optical element on encapsulation unit 230.Additionally, in other embodiments, optical microstructures unit 240 can also be
Holographic optics (holographic optical element, HOE), computer full figure element (computer-
Generated holographic optical element) structure, Fresnel lens (fresnel lens) structure or lens
Grating.
In the present embodiment, light source cell 210 and light detecting unit 220 are positioned at the same side of biological tissue 50.Concrete and
Speech, the first light beam B1 and the second light beam B2 from light source cell 210 can be guided by first wave guide 232, micro-to be transferred to optics
Construction unit 240.Now, optical microstructures unit 240 can be by the first light beam B1 and the second light beam B2 diffraction.Set by suitable
The diffraction structure of photometric microstructure unit 240, can make the first light beam B1 and second light beam B2 energy after diffraction concentrate on
The diffraction light (such as-1 grade or the diffraction light of+1 grade) of its one-level.Consequently, it is possible to the first light beam B1 and the second light beam B2 is the most permissible
Intensively it is irradiated in biological tissue 50.For example, the first light beam B1 and the second light beam B2 can intensively be irradiated in the mankind
In blood capillary in the skin corium of skin.Then, the first light beam B1 and the second light beam B2 can be scattered and reflection by biological tissue 50
To optical microstructures unit 240.Then, the first light beam B1 and the second light beam B2 is diffracted into second by optical microstructures unit 240
Waveguide 234, but the first light beam B1 and the second light beam B2 is directed to light detecting unit 220 by second waveguide 234 again.By suitably
The diffraction structure of ground design optical microstructures unit 240, can make the first light beam B1 and the second light beam B2 energy quantity set after diffraction
In in the diffraction light (such as-1 grade or the diffraction light of+1 grade) of certain one-level, and then make the first light beam B1 and the second light beam B2 by light
After learning microstructure unit 240 diffraction and being guided by the second photoconduction 234, intensively it is irradiated in light detecting unit 220.Therefore, at this
In embodiment, owing to the first light beam B1 and the second light beam B2 from light source cell 210 is intensively irradiated in biological tissue 50,
And reflect from biological tissue 50 and the first light beam B1 and the second light beam B2 that scatter the most intensively are irradiated in light detecting unit 220
On, therefore the noise of the light that light detecting unit 220 is detected is less, and namely signal noise is higher.Consequently, it is possible to light is detectd
Surveying unit 220 just can be more loyal and react first detected exactly by the signal of telecommunication converted for the light detected
Light beam B1 and the light intensity of the second light beam B2, effectively to reduce the False Rate of detector 100, and then promote detector 100
Accuracy and reliability.In the present embodiment, pitch (the pitch) (example of the optical microstructures in optical microstructures unit 240
Such as the pitch between two circular fringeses adjacent in the optical microstructures unit 240 of Figure 1A, the most e.g. phase in diffraction optical element
Adjacent two interfringe pitches) e.g. fall in the range of 0.05 to 100 micron.
Fig. 2 is the band oxygen haemachrome abosrption spectrogram with deoxy-hemoglobin of the mankind.Refer to Figure 1A to Fig. 1 C and Fig. 2,
The detector 100 of the present embodiment can be used to detect the blood oxygen concentration in the blood capillary in human dermal's layer.As shown in Figure 2, band
Oxygen haemachrome differs with the absorption spectrum of deoxy-hemoglobin, and therefore band oxygen haemachrome and deoxy-hemoglobin are 660 for wavelength
The HONGGUANG (the i.e. first light beam B1) of nanometer differs with the absorbance of the infrared light (the i.e. second light beam B2) that wavelength is 910 nanometers.
For the HONGGUANG that wavelength is 660 nanometers, the absorbance of deoxy-hemoglobin is higher than the absorbance of band oxygen haemachrome.But, for ripple
The infrared light of a length of 910 nanometers, then be the absorbance absorbance higher than deoxy-hemoglobin of band oxygen haemachrome.Therefore, when micro-blood
When band oxygen haemachrome in pipe is the highest with the concentration proportion of deoxy-hemoglobin, the first light beam that light detecting unit 220 is detected
The intensity ratio of B1 and the second light beam B2 is the highest；Otherwise, when the concentration of the band oxygen haemachrome in blood capillary Yu deoxy-hemoglobin
When ratio is the lowest, the first light beam B1 and the intensity ratio of the second light beam B2 that light detecting unit 220 is detected are the lowest.So
One, after being calculated according to the light intensity of the first light beam B1 measured by light detecting unit 220 and the second light beam B2,
Obtain the blood oxygen concentration in biological tissue 50.
In the present embodiment, detector 100 also includes computing unit 110, is electrically connected to light detecting unit 220, its
The the first light beam B1 detected and the second light beam B2 is converted to signal of telecommunication E, and computing unit 110 by middle smooth detecting unit 220
Physiological parameter (being blood oxygen concentration in the present embodiment) is calculated according to signal of telecommunication E.Additionally, in the present embodiment, due to first
Light beam B1 and the second light beam B2 is sent in turn, and therefore light detecting unit 220 is detected when the first light beam B1 sends
Light intensity is the light intensity of the first light beam B1, and the light intensity that detecting unit 220 is detected when the second light beam B2 sends
It is the light intensity of the second light beam B2.By this mode, computing unit 110 just can interpolate that out that signal of telecommunication E when is generation
The light intensity of table the first light beam B1, and signal of telecommunication E when is the light intensity representing the second light beam B2.In other words, list is calculated
Unit 110 is the light intensity of light intensity and the second light beam B2 obtaining the first light beam BI in the way of time multitask.
In the present embodiment, the first light beam B1 measured by light detecting unit 220 and the signal of the second light beam B2
Noise ratio is higher, and therefore detector 100 can be as the higher oximeter (oXimeter) of accuracy and reliability.Additionally, by
Higher in above-mentioned signal noise, therefore computing unit 110 can use complexity algorithm to reduce noise, and then reduce
The cost of manufacture of computing unit 110 and operation time.
In the present embodiment, detecting module 200 also includes outer housing 260, cover light source cell 210, light detecting unit 220 and
Encapsulation unit 230.Outer housing 260 can block from extraneous ambient light, to avoid light detecting unit 220 affected by ambient light
And produce noise.Consequently, it is possible to the signal noise ratio measured by light detecting unit 220 just can promote further.
Additionally, in the present embodiment, detecting module 200 also includes light separating element 250, its separate first wave guide 232 with
Second waveguide 234.The first light beam B1 and the second light beam B2 that light separating element 250 can be prevented effectively from from light source cell 210 exist
Light detecting unit 220 it is transferred in the case of not irradiating biological tissue 50, so can promotion signal noise ratio further.
Fig. 3 A is the schematic top plan view of the detector of another embodiment of the present invention, and Fig. 3 B is the detector edge of Fig. 3 A
The generalized section of III-III line, and the detector that Fig. 3 C is Fig. 3 A is along the generalized section of IVIV line.Refer to figure
3A to Fig. 3 C, the detector 100 of detector 100a with Figure 1A of the present embodiment is similar, and the most identical label represents identical
Or similar element, and both difference is as described below.
In the detecting module 200a of the detector 100a of the present embodiment, light source cell 210a includes the first light-emitting component
212 and material for transformation of wave length 216a.First light-emitting component 212 has light-emitting area 213, and in order to send original from light-emitting area 213
Light beam B0.Material for transformation of wave length 216a covers the Part I 2131 of light-emitting area 213, and exposes second of light-emitting area 213
Dividing 2132, at least part of original beam B0 wherein sent from Part I 2131 is converted into second by material for transformation of wave length 216a
Light beam B2, and original beam B0 sent from Part II 2132 forms the first light beam B1.In the present embodiment, original beam B0
Wavelength and the wavelength of the first light beam B1 mutually the same.Stated differently, since original beam B0 sent from Part II 2132
Not over material for transformation of wave length 216a, therefore original beam B0 of this part is the first light beam B1.In the present embodiment, ripple
Long transition material 216a for example, fluorescent material (phosphor).But, in other embodiments, Part I 2131 and second
Divide and also can be covered each by two kinds of different material for transformation of wave length, respectively original beam B0 to be converted to the second light beam on 2132
B2 and the first light beam B1, the now wavelength of the original beam B0 wavelength less than the first light beam B1, and the ripple less than the second light beam B2
Long.
Additionally, in the present embodiment, light detecting unit 220a includes the first optical detector 222a and the second optical detector
224a, optical microstructures unit 240a make to be transferred to the first optical detector 222a from the first light beam B1 of biological tissue 50, and
Optical microstructures unit 240a makes the second light beam B2 from biological tissue 50 be transferred to the second optical detector 224a.In this enforcement
In example, optical microstructures unit 240a includes the first optical microstructures 242a and the second optical microstructures 244a.First optics is micro-
Structure 242a is configured on the bang path of the first light beam B1 and the second light beam B2 of light source cell 210a, so that from light
The first light beam B1 and the second light beam B2 of source unit 210a are transferred to biological tissue 50.Second optical microstructures 244a is configured at
On the bang path of the first light beam B1 and the second light beam B2 of biological tissue 50, so that from the first light beam of biological tissue 50
B1 and the second light beam B2 is transferred to light detecting unit 220a.
Specifically, the first optical microstructures 242a is by the first light beam B1 and the second light beam B2 from first wave guide 232
In different direction sets, to be irradiated in biological tissue 50.Additionally, from the first light beam B1 of biological tissue 50 and the second light
Bundle B2 is concentrated toward the first optical detector 222a and the second optical detector 224a respectively by the second optical microstructures 244a.In other words
Say, owing to the first optical detector 222a and the second optical detector 224a can detect the first light beam B1 and the second light beam B2 respectively,
Therefore light source cell 210a can be simultaneously emitted by the first light beam B1 and the second light beam B2.In other words, light detecting unit 220a is to adopt
The first light beam B1 and the second light beam B2 is detected by the mode of spatial reuse.
In the present embodiment, the first optical detector 222a and the second optical detector 224a for example, photodiode, and the
One optical microstructures 242a and the second optical microstructures 244a for example, diffraction optical element (diffractive optical
Element, DOE) structure.Additionally, in the present embodiment, the first optical microstructures 242a and the second optical microstructures 244a is such as
It is respectively the surface micro-structure of first wave guide 232 and second waveguide 234.But, in another embodiment, the first optical microstructures
242a and the second optical microstructures 244a can be two panels blooming piece, and it is respectively arranged on first wave guide 232 and second waveguide 234
On, attach the most respectively or be bearing in first wave guide 232 and second waveguide 234.In other words, the first optical microstructures
242a and the second optical microstructures 244a can also be two and attach respectively or be bearing in first wave guide 232 and second waveguide B4
Diffraction optical element.Additionally, in other embodiments, the first optical microstructures 242a and the second optical microstructures 244a also may be used
With pure gold as optical element (holographic optical elementrHOE), computer gold element (computer-
Generated holographic optical element) structure, Fresnel lens (fresnel lens) structure or lens
Grating.In the present embodiment, pitch (the first of such as Fig. 3 A of the first optical microstructures 242a and the second optical microstructures 244a
In optical microstructures unit 242a and the second optical microstructures unit 244a, the adjacent two interfringe pitches of arcuation, the most e.g. spread out
Penetrate the adjacent two interfringe pitches in optical element) e.g. fall in the range of 0.05 to 100 micron.
In the present embodiment, via being suitably designed the diffraction structure of the first optical microstructures 242a, can make from first
The energy of the first light beam B1 and the second light beam B2 of waveguide 232 concentrates on the diffraction light of its one-level (such as-1 grade or+1 grade), because of
This first light beam B1 and the second light beam B2 can be respectively facing different directions and concentrate on the diverse location of biological tissue 50.So
After, the second optical microstructures 244a can make the energy of the first light beam B1 and the second light beam B2 from biological tissue 50 concentrate on it
On the diffraction light of one-level (such as-1 grade or+1 grade), the first light beam B1 and the second light beam B2 therefore from biological tissue 50 can distinguish
Concentrate on the first optical detector 222a and the second optical detector 224a.Consequently, it is possible to the signal measured by detector 100a
Noise ratio just can be sufficiently elevated, and then increases accuracy and the reliability of detector 100a.
In the present embodiment, computing unit 110 can receive from the first optical detector 222a signal of telecommunication E1 with from the
The signal of telecommunication E2 of two optical detector 224a, wherein signal of telecommunication E1 is corresponding to the light intensity of the first light beam B1, and signal of telecommunication E2 is corresponding
Light intensity in the second light beam B2.
In the present embodiment, the first optical microstructures 242a and the second optical microstructures 244a is separate two structures,
But, in other embodiments, the first optical texture 242a and the second optical texture 244a can also be made in a piece of optics
On diaphragm.
Fig. 4 A and Fig. 4 B is the generalized section of the detector of another embodiment of the present invention.Refer to Fig. 4 A and figure
4B, the detector 100 of detector 100b with Figure 1B and Fig. 1 C of the present embodiment is similar, and both difference is as described below.
In the detecting module 200b of the detector 100b of the present embodiment, between optical microstructures unit 240b and encapsulation unit 230
Maintain spacing G.For example, optical microstructures unit 240b to be fabricated to the form of lid, and can be fixed on outer housing 260,
And cover first wave guide 232 and second waveguide 234.Optical microstructures unit 240b can have diffraction optical element structure, complete
As optical element, computer gold element, fresnel lenus structure or lenticulation.
Fig. 5 A to Fig. 5 C is the schematic top plan view of the detector of other three embodiments of the present invention.Refer to Fig. 5 A extremely
Fig. 5 C, detector 100c, 100d, 100e are similar with the detector 100 of Figure 1A, and its difference is as described below.Detector
100c, 100d, 100e respectively include multiple detecting module 200, and these detecting modules 200 are arranged in two-dimensional array, each of which
The thin portion structure of detecting module 200 is identical with the detecting module 200 of Figure 1A, therefore no longer repeats at this, and at Fig. 5 A to Fig. 5 C
In the most no longer show the thin portion structure of detecting module 200, detailed structure refer to the explanation of Figure 1A and correspondence thereof.
In fig. 5, these detecting modules 200 are arranged in rectangle two-dimensional array, and these detecting modules are fixed on connection sheet
On 120.In figure 5b, these detecting modules 200 are arranged in dislocation type two-dimensional array, the most cellular two-dimensional array, and this
A little detecting modules are fixed on connection sheet 120.In figure 5 c, these detecting modules 200 are arranged in circular array, and these detectings
Module is fixed on connection sheet 120e.Connect sheet 120,120e can be bendable connection sheet, and makes these detecting modules 200
Can bend along the shape of skin, and be attached on the diverse location of skin.Consequently, it is possible to it is different just can to monitor human body simultaneously
The physiological parameter (such as blood oxygen concentration) of position.If the quantity of these detecting modules 200 is more than enough and reaches the most intensive, and can physiology
Parameter image (such as blood oxygen concentration image), so can obtain the distribution of physiological parameter.Connect sheet 120, the shape of 120e
Can be varied from along with the difference of the shape of two-dimensional array.For example, connecting sheet 120 is rectangle, connects sheet 120e then
For circle.But, in other embodiments, these detecting modules 200 can also be arranged in the two-dimensional array of other shapes, and connects
Contact pin can also be in other shapes.Additionally, computing unit 110 is then electrically connected to these detecting modules 200, to detect according to these
Survey the light intensity measured by module 200 to calculate.
Additionally, the detecting module 200 in detector 100c, 100d, 100e can also be with the detecting mould of above-described embodiment
The detecting module of block 200a or 200b or other embodiments replaces.
In sum, in the detector of embodiments of the invention, owing to using optical microstructures unit so that first
Light beam and the second light beam are intensively irradiated in biological tissue, and utilize optical microstructures unit to make first from biological tissue
Light beam and the second light beam are intensively irradiated on light detecting unit, therefore the first light beam and second measured by light detecting unit
The signal noise of light beam is higher.Consequently, it is possible to detector just can have relatively low False Rate, higher accuracy and higher
Reliability.Additionally, due to above-mentioned signal noise is higher, therefore computing unit can use the algorithm of complexity to reduce
Noise, and then reduce cost of manufacture and the operation time of computing unit.
Although the present invention is disclosed above with embodiment, so it is not limited to the present invention, any art
Middle those of ordinary skill, without departing from the spirit and scope of the present invention, as change and modification, the therefore present invention that can make part
Protection domain when being as the criterion depending on as defined in claim.
Claims (21)
1. a detecting module, this detecting module includes:
Light source cell, in order to send the first light beam and the second light beam, wherein the wavelength of this first light beam is different from this second light beam
Wavelength；
Light detecting unit；
Encapsulation unit, is configured on this light source cell and this light detecting unit, and is positioned at this first light from this light source cell
On the bang path of bundle and this second light beam；And
Optical microstructures unit, is configured on the bang path of this first light beam and this second light beam；
This first light beam that wherein this light source cell is sent and this second light beam pass sequentially through this encapsulation unit, by this optics
Microstructure unit, it is transferred to a biological tissue, by this optical microstructures unit, by this encapsulation unit and be transferred to this light and detect
Survey unit.
Detecting module the most according to claim 1, wherein this encapsulation unit includes waveguide, covers this light source cell and this light
Detecting unit.
Detecting module the most according to claim 1, wherein this optical microstructures unit is located on this encapsulation unit.
Detecting module the most according to claim 1, between wherein maintaining between this optical microstructures unit and this encapsulation unit
Away from.
Detecting module the most according to claim 1, wherein this optical microstructures unit is the micro-knot in surface of this encapsulation unit
Structure.
Detecting module the most according to claim 1, wherein this optical microstructures unit includes diffraction optical element structure, complete
As optical element, computer full figure component structure, fresnel lens structure or lenticulation.
Detecting module the most according to claim 1, wherein this encapsulation unit includes:
First wave guide, covers this light source cell；And
Second waveguide, covers this light detecting unit, and wherein this detecting module also includes light separating element, separate this first wave guide with
This second waveguide.
Detecting module the most according to claim 1, wherein this detecting module also includes outer housing, covers this light source cell, is somebody's turn to do
Light detecting unit and this encapsulation unit.
Detecting module the most according to claim 1, wherein this light source cell includes: the first light-emitting component, in order to send this
First light beam；And second light-emitting component, in order to send this second light beam, wherein this first light-emitting component and this second luminous unit
Part sends this first light beam and this second light beam in turn, and this light detecting unit includes optical detector.
Detecting module the most according to claim 1, wherein this light detecting unit includes: the first optical detector, wherein this light
Learning microstructure unit makes this first light beam from this biological tissue be transferred to this first optical detector；And second light detecting
Device, wherein this optical microstructures unit makes to be transferred to this second optical detector from this second light beam of this biological tissue, and should
Light source cell is simultaneously emitted by this first light beam and this second light beam.
11. detecting modules according to claim 1, wherein this light source cell includes: light-emitting component, has light-emitting area, and
In order to send original beam from this light-emitting area, wherein the wavelength of this original beam is mutually the same with the wavelength of this first light beam；With
And material for transformation of wave length, cover the Part I of this light-emitting area, and expose the Part II of this light-emitting area, wherein from this first
This original beam at least part of that part sends is converted into this second light beam by this material for transformation of wave length, and sends out from this Part II
This original beam gone out forms this first light beam.
12. detecting modules according to claim 1, wherein this optical microstructures unit includes: the first optical microstructures, joins
Be placed on the bang path of this first light beam and this second light beam of this light source cell so that from this light source cell should
First light beam and this second light beam are transferred to this biological tissue；And second optical microstructures, it is configured at from this biological tissue
This first light beam and this second light beam bang path on so that from this first light beam of this biological tissue and this second light
Bundle is transferred to this light detecting unit.
13. detecting modules according to claim 1, wherein this light source cell includes light emitting diode, organic light-emitting diodes
Pipe or laser diode.
14. detecting modules according to claim 1, wherein this encapsulation unit is suitable to by this first light beam and this second light beam
Penetrate.
15. detecting modules according to claim 1, wherein this first light beam all falls within HONGGUANG with the wavelength of this second light beam
With in the wave-length coverage of infrared light.
16. detecting modules according to claim 1, wherein this light source cell and this light detecting unit are positioned at this biological tissue
The same side.
17. detecting modules according to claim 1, wherein this light detecting unit includes photodiode.
18. 1 detectors, in order to detect a physiological parameter of a biological tissue, this detector includes at least one claim
Detecting module described in 1.
19. detectors according to claim 18, also include computing unit, are electrically connected to the light in this detecting module
Detecting unit, wherein this first light beam and this second Beam Transformation detected is the signal of telecommunication by this light detecting unit, and this meter
Calculate unit and calculate this physiological parameter according to this signal of telecommunication.
20. detectors according to claim 18, wherein this physiological parameter is blood oxygen concentration.
21. detectors according to claim 18, wherein this at least one detecting module is multiple detecting module, the plurality of
Detecting module is arranged in two-dimensional array.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261684819P | 2012-08-20 | 2012-08-20 | |
| US61/684,819 | 2012-08-20 | ||
| TW102127307 | 2013-07-30 | ||
| TW102127307A TWI477759B (en) | 2012-08-20 | 2013-07-30 | Detecting module and detecting device |
Publications (2)
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|---|---|
| CN103630506A CN103630506A (en) | 2014-03-12 |
| CN103630506B true CN103630506B (en) | 2016-10-26 |
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| CN201310365671.3A Active CN103630506B (en) | 2012-08-20 | 2013-08-20 | Detection module and detection device |
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| US (2) | US9883824B2 (en) |
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Also Published As
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| US10117612B2 (en) | 2018-11-06 |
| US20180132771A1 (en) | 2018-05-17 |
| US9883824B2 (en) | 2018-02-06 |
| CN103630506A (en) | 2014-03-12 |
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