CN103623225A - Traditional Chinese medicine preparation for treating subacute thyroiditis - Google Patents
Traditional Chinese medicine preparation for treating subacute thyroiditis Download PDFInfo
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- CN103623225A CN103623225A CN201310582095.8A CN201310582095A CN103623225A CN 103623225 A CN103623225 A CN 103623225A CN 201310582095 A CN201310582095 A CN 201310582095A CN 103623225 A CN103623225 A CN 103623225A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating subacute thyroiditis. Subacute thyroiditis belongs to struma colloides of traditional Chinese medicine, and the main pathology is resulted from blocking of qi, phlegm and stasis. Traditional Chinese herbal medicines, namely, textile screw pine seed, sheathed aconite, cirsium lineare, lindera aggregate leaves, micromeria, pyrola, trichoglottis philippinensis, Chinese mosla, sago flower, root of schoch craspedolobium, narrowleaf falsepimpernel herb, liquorice and lindera fragrans which have the functions of activating blood and dissolving stasis, regulating vital energy to relieve pain, clearing heat and toxic materials, warming the middle warmer and tonifying spleen, and reducing phlegm and resolving masses are prepared into decoction. Clinical tests show that the total effective rate is 94.6%, which is greatly superior to that of a control group, so that the preparation is worthy for clinical popularization and application.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine preparation for the treatment of subacute thyroiditis.
Background technology
Subacute thyroiditis (subacute thyroiditis) is to produce by virus or virus the apyetous thyroid inflammation that allergy causes, shows as body of gland enlargement, pain.Claim again De Quervain thyroiditis, subacute thyroiditis, subacute thyroiditis.More common in thyroiditis.Because being different from the shorter acute suppurative thyroiditis of the course of disease, be also different from the very long lymphocytic thyroiditis of the course of disease, therefore be referred to as subacute thyroiditis.The primary disease course of disease is different in size, is generally 2-3 month, is half a year or longer, and rear majority is alleviated automatically, no sequel, but have tendency of recurrence.At present, western medical treatment lacks more satisfactory specific drug, and long-term taking often has side effects, and inventor, through clinical trial for many years, utilizes treatment by Chinese herbs to obtain good curative effect.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of subacute thyroiditis.Subacute thyroiditis belongs to Chinese medicine goiter category.Main pathology is by due to gas, expectorant, stasis of blood heap soil or fertilizer over and around the roots knot.The traditional Chinese medical science thinks that Therapeutic Principle is blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain, heat-clearing and toxic substances removing, warming middle-JIAO and strengthening the spleen, dissipating phlegm and resolving masses.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment subacute thyroiditis is made by the Chinese medicine of following weight portion: Fructus Pandani tectorii 30-35 part, Radix Aconiti Vaginati 15-25 part, Herba Cirsii linearis 15-25 part, Folium Linderae strychnifoliae 3-10 part, Herba Micromeriae Biflorae 5-10 part, Herba Pyrolae 25-50 part, Herba Cleisostomatis scolopendrifolii 25-35 part, Herba Moslae Chinensis 10-20 part, Flos Cycadis Revolute 20-30 part, Radix craspedolobii schochii 9-15 part, Lindernia angustifolia (Benth.) Wettst. 16-20 part, Radix Glycyrrhizae 2-12 part, Cortex Linderae Fragrantis 10-15 part.
Preferably, 32 parts of Fructus Pandani tectoriis, 20 parts of Radix Aconiti Vaginatis, 20 parts of Herba Cirsii lineariss, 6 parts of Folium Linderae strychnifoliaes, 8 parts of Herba Micromeriae Bifloraes, 35 parts of Herba Pyrolaes, 30 parts of Herba Cleisostomatis scolopendrifoliis, 16 parts of Herba Moslae Chinensis, 12 parts, Radix craspedolobii schochii, 25 parts of Flos Cycadis Revolutes, 18 parts of Lindernia angustifolia (Benth.) Wettst.s, 7 parts, Radix Glycyrrhizae, 12 parts of Cortex Linderae Fragrantis.
Preparation method is made decoction by above-mentioned Chinese medicine decocting.
In side: Fructus Pandani tectorii, Radix Aconiti Vaginati spleen invigorating, reduce phlegm, eliminating stagnation; Herba Cirsii linearis promoting blood circulation to remove blood stasis, removing toxic substances; Flos Cycadis Revolute, Radix craspedolobii schochii blood circulation promoting and blood stasis dispelling; Folium Linderae strychnifoliae warming middle-JIAO is regulated the flow of vital energy; Herba Micromeriae Biflorae warming middle-JIAO, regulates the flow of vital energy, pain relieving; Herba Pyrolae expelling wind and activating blood circulation; Herba Cleisostomatis scolopendrifolii heat-clearing and toxic substances removing, hemostasis; Herba Moslae Chinensis vital energy regualting and blood circulation-promoting, pain relieving; Lindernia angustifolia (Benth.) Wettst. clearing away heat-damp and promoting diuresis, cooling blood and removing stasis; Radix Glycyrrhizae warming middle-JIAO and strengthening the spleen; Cortex Linderae Fragrantis circulation of qi promoting.
Clinical data
1, this group of physical data patient 110 examples, are subacute thyroiditis out-patient, by table of random number, case are divided into treatment group and each 55 examples of matched group at random.Treatment group man 27 examples, female's 28 examples; 25～48 years old age, average 32.6 years old, the course of disease 6 months 1 year.Matched group man 28 examples, female's 27 examples; Age is 26～49 years old, average 33.1 years old, and the course of disease 6 months～1 year.Two groups of patient's comparisons aspect age, sex, the course of disease, no significant difference (P > 0.05), has comparability.
2, before diagnostic criteria (1) onset, can there is upper respiratory tract infection history.(2) in various degree heating, weak, malasia.Thyroid is enlargement in various degree, and quality is hard and irregular, can be nodositas, has conscious pain and tenderness, is often radiated to the basal part of the ear, occipitalia, neck side, pharyngeal, lower jaw etc.Thyromegaly can be prolonged and offside by a side.(3) from the beginning of can there be tachycardia, the hyperthyroidism clinical manifestation such as To Be Protected from Heat, perspiration, irascible temperament, erythrocyte sedimentation rate speeds.(4) thyroid 131 iodine uptake rates obviously reduce, and initial stage serum TSH concentration reduces, and FT3, FT4 Elityran (Tg) value raise, and the later stage recovers normal gradually.Indivedual patients can develop into hypothyroidism.(5) by adrenocortical hormones in treating, can make symptom, sign alleviate rapidly.
3, Therapeutic Method treatment group patient takes Chinese medicine preparation of the present invention, take Fructus Pandani tectorii 32g, Radix Aconiti Vaginati 20g, Herba Cirsii linearis 20g, Folium Linderae strychnifoliae 6g, Herba Micromeriae Biflorae 8g, Herba Pyrolae 35g, Herba Cleisostomatis scolopendrifolii 30g, Herba Moslae Chinensis 16g, Radix craspedolobii schochii 12g, Flos Cycadis Revolute 25g, Lindernia angustifolia (Benth.) Wettst. 18g, Radix Glycyrrhizae 7g, Cortex Linderae Fragrantis 12g, decocting becomes decoction, potion, divided and sooner or later took for 2 times every day; The oral prednisone acetate tablets of matched group, each 5mg, every day 3 times.A course for the treatment of two Mondays, two groups all serve on four courses for the treatment of.
4, criterion of therapeutical effect is cured: symptom and sign disappear, and serum FT 3, FT4, TSH are normal, erythrocyte sedimentation rate recovers normal.Effective: symptom and sign are obviously alleviated, wart is swollen, wart pain is basic disappears, and serum FT 3, FT4, TSH are normal, erythrocyte sedimentation rate recovers normal substantially.Effective: symptom and sign are obviously alleviated, serum FT 3, FT4, TSH are normal, erythrocyte sedimentation rate makes moderate progress.Invalid: symptom and sign have no improvement, serum FT 3, FT4 still increase or undulatory property increases, and TSH still reduces, and erythrocyte sedimentation rate still increases.
5, curative effect comparison after four courses for the treatment of of two groups of therapeutic outcomes treatment, treatment group 55 examples, wherein cure 20 examples (36.4%), effective 22 examples (40%), effective 10 examples (18.2%), invalid 3 examples (5.4%), total effective rate 94.6%; Matched group 55 examples, wherein cure 5 examples (9.1%), effective 18 examples (32.7%), effective 15 examples (27.3%), invalid 17 examples (30.9%), total effective rate 69.1%.Two groups of comparisons, treatment group cure rate, total effective rate are obviously better than matched group, have comparability (P < 0.05).
The specific embodiment
Embodiment mono-: take Fructus Pandani tectorii 32g, Radix Aconiti Vaginati 20g, Herba Cirsii linearis 20g, medicine leaf 6g, Herba Micromeriae Biflorae 8g, Herba Pyrolae 35g, Herba Cleisostomatis scolopendrifolii 30g, Herba Moslae Chinensis 16g, Radix craspedolobii schochii 12g, Flos Cycadis Revolute 25g, Lindernia angustifolia (Benth.) Wettst. 18g, Radix Glycyrrhizae 7g, Cortex Linderae Fragrantis 12g, above-mentioned Chinese medicine decocting is made to decoction.
Embodiment bis-: take Fructus Pandani tectorii 35g, Radix Aconiti Vaginati 25g, Herba Cirsii linearis 15g, Folium Linderae strychnifoliae 3g, Herba Micromeriae Biflorae 5g, Herba Pyrolae 25g, Herba Cleisostomatis scolopendrifolii 35g, Herba Moslae Chinensis 10g, Radix craspedolobii schochii 9g, Flos Cycadis Revolute 30g, Lindernia angustifolia (Benth.) Wettst. 20g, Radix Glycyrrhizae 12g, Cortex Linderae Fragrantis 15g, above-mentioned Chinese medicine decocting is made to decoction.
Embodiment tri-: take Fructus Pandani tectorii 30g, Radix Aconiti Vaginati 15g, Herba Cirsii linearis 25g, Folium Linderae strychnifoliae 10g, Herba Micromeriae Biflorae 10g, Herba Pyrolae 50g, Herba Cleisostomatis scolopendrifolii 25g, Herba Moslae Chinensis 20g, Radix craspedolobii schochii 15g, Flos Cycadis Revolute 20g, Lindernia angustifolia (Benth.) Wettst. 16g, Radix Glycyrrhizae 2g, Cortex Linderae Fragrantis 10g, above-mentioned Chinese medicine decocting is made to decoction.
Claims (2)
1. treat a Chinese medicine preparation for subacute thyroiditis, it is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: Fructus Pandani tectorii 30-35 part, Radix Aconiti Vaginati 15-25 part, Herba Cirsii linearis 15-25 part, Folium Linderae strychnifoliae 3-10 part, Herba Micromeriae Biflorae 5-10 part, Herba Pyrolae 25-50 part, Herba Cleisostomatis scolopendrifolii 25-35 part, Herba Moslae Chinensis 10-20 part, Flos Cycadis Revolute 20-30 part, Radix craspedolobii schochii 9-15 part, Lindernia angustifolia (Benth.) Wettst. 16-20 part, Radix Glycyrrhizae 2-12 part, Cortex Linderae Fragrantis 10-15 part.
2. a kind of Chinese medicine preparation for the treatment of subacute thyroiditis according to claim 1, is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: 32 parts of Fructus Pandani tectoriis, 20 parts of Radix Aconiti Vaginatis, 20 parts of Herba Cirsii lineariss, 6 parts of Folium Linderae strychnifoliaes, 8 parts of Herba Micromeriae Bifloraes, 35 parts of Herba Pyrolaes, 30 parts of Herba Cleisostomatis scolopendrifoliis, 16 parts of Herba Moslae Chinensis, 12 parts, Radix craspedolobii schochii, 25 parts of Flos Cycadis Revolutes, 18 parts of Lindernia angustifolia (Benth.) Wettst.s, 7 parts, Radix Glycyrrhizae, 12 parts of Cortex Linderae Fragrantis.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112138067A (en) * | 2020-10-12 | 2020-12-29 | 青岛大学附属医院 | Traditional Chinese medicine for treating iodine refractory differentiated thyroid cancer and application |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101152535A (en) * | 2007-09-15 | 2008-04-02 | 尹克华 | Traditional Chinese medicine for treating subacute thyroiditis |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101152535A (en) * | 2007-09-15 | 2008-04-02 | 尹克华 | Traditional Chinese medicine for treating subacute thyroiditis |
Non-Patent Citations (1)
| Title |
|---|
| 冯建华: "亚急性甲状腺炎的中医治疗", 《山东中医药大学学报》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112138067A (en) * | 2020-10-12 | 2020-12-29 | 青岛大学附属医院 | Traditional Chinese medicine for treating iodine refractory differentiated thyroid cancer and application |
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Inventor after: Shen Zhaohong Inventor after: Cui Yanxiang Inventor before: Shen Zhaohong |
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Effective date of registration: 20170510 Address after: Nanjing road 226100 Jiangsu Sijia town of Haimen city of Nantong province No. 78 Patentee after: HAIMEN RUITAI TEXTILE TECHNOLOGY Co.,Ltd. Address before: 276400 Linyi health center, Yishui, Shandong, China, Yishui Central Hospital, No. 17, Patentee before: Shen Zhaohong |
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