CN103598579A - Health-care food containing soy isoflavone - Google Patents
Health-care food containing soy isoflavone Download PDFInfo
- Publication number
- CN103598579A CN103598579A CN201310552672.9A CN201310552672A CN103598579A CN 103598579 A CN103598579 A CN 103598579A CN 201310552672 A CN201310552672 A CN 201310552672A CN 103598579 A CN103598579 A CN 103598579A
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- CN
- China
- Prior art keywords
- health
- care food
- osteoporosis
- soy isoflavone
- bone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000013305 food Nutrition 0.000 title abstract 4
- 235000003687 soy isoflavones Nutrition 0.000 title abstract 3
- 235000021283 resveratrol Nutrition 0.000 claims abstract description 4
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 claims description 8
- 150000002515 isoflavone derivatives Chemical class 0.000 claims description 8
- 235000008696 isoflavones Nutrition 0.000 claims description 8
- 235000013402 health food Nutrition 0.000 claims description 5
- 210000000988 bone and bone Anatomy 0.000 abstract description 9
- 239000003814 drug Substances 0.000 abstract description 5
- 239000002994 raw material Substances 0.000 abstract description 2
- QNVSXXGDAPORNA-UHFFFAOYSA-N Resveratrol Natural products OC1=CC=CC(C=CC=2C=C(O)C(O)=CC=2)=C1 QNVSXXGDAPORNA-UHFFFAOYSA-N 0.000 abstract 1
- LUKBXSAWLPMMSZ-OWOJBTEDSA-N Trans-resveratrol Chemical compound C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-OWOJBTEDSA-N 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 229940016667 resveratrol Drugs 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 description 17
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 7
- 229910052791 calcium Inorganic materials 0.000 description 7
- 239000011575 calcium Substances 0.000 description 7
- 206010017076 Fracture Diseases 0.000 description 5
- 241000700159 Rattus Species 0.000 description 5
- 230000037182 bone density Effects 0.000 description 5
- 210000000689 upper leg Anatomy 0.000 description 5
- 208000010392 Bone Fractures Diseases 0.000 description 4
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 238000004904 shortening Methods 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 208000008035 Back Pain Diseases 0.000 description 2
- 208000008930 Low Back Pain Diseases 0.000 description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 description 2
- 210000000038 chest Anatomy 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000002651 drug therapy Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 201000000916 idiopathic juvenile osteoporosis Diseases 0.000 description 2
- 230000000241 respiratory effect Effects 0.000 description 2
- 206010065687 Bone loss Diseases 0.000 description 1
- 241001456553 Chanodichthys dabryi Species 0.000 description 1
- 206010010214 Compression fracture Diseases 0.000 description 1
- 206010016997 Forearm fracture Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000001164 Osteoporotic Fractures Diseases 0.000 description 1
- 208000002103 Shoulder Fractures Diseases 0.000 description 1
- 241001122767 Theaceae Species 0.000 description 1
- 208000003443 Unconsciousness Diseases 0.000 description 1
- 229930003316 Vitamin D Natural products 0.000 description 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 230000037180 bone health Effects 0.000 description 1
- 230000037118 bone strength Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 239000007884 disintegrant Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000000245 forearm Anatomy 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000003284 homeostatic effect Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000001009 osteoporotic effect Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a health-care food containing soy isoflavone. The health-care food is mainly prepared from resveratrol and soy isoflavone as main raw materials. By adopting the traditional Chinese medicine, namely the health-care food, the bone mineral densities of middle aged and elderly people can be increased.
Description
Technical field
The invention belongs to biomedicine field, be specifically related to a kind of health food that contains isoflavones.
Background technology
Osteoporosis is a kind of common disease and frequently-occurring disease, and it is seriously threatening the elderly, and especially postmenopausal women is healthy.The complication such as the fracture being caused by osteoporosis, have caused great misery to patient, return society and family and have brought heavy economy and living burden.According to reports, the possibility that the osteoporotic women of generation occurred hip, backbone, forearm or proximal humeral fracture in 10 years later in 50 years old is up to 45%; Be greater than 65 years old old man when unconscious falling, have 87% can cause osteoporotic fracture.China the elderly's absolute quantity accounts for No. 1 in the world, and along with the growth of growth in the living standard and population life, the aged sharply increases, and therefore, the diagnosis of osteoporosis and control thereof just seem very important.
Osteoporosis can be divided into three major types, and a class is primary osteoporosis, is a kind of physiological retrogression pathological changes that must occur with advancing age.Equations of The Second Kind is secondary osteoporosis, and it is the osteoporosis of being brought out by some factors such as Other diseases or medicines.The 3rd class is idiopathic osteoporosis disease, is more common in teenager or the adult of 8～14 years old, mostly has family's heredity medical history, and women is more than the male sex.The osteoporosis that gravid woman and women breast-feeding their children occur also can be listed idiopathic osteoporosis in, to cause people's attention.
The main clinical manifestation of osteoporosis and sign are: pain, height shortening, hunchback, fragility fractures and Respiratory Disturbances etc.
1) pain
Pain is the common sympton of osteoporosis, and its reason is mainly that bone absorbs to be increased because bone conversion is high.In bone absorption process, bone trabecular destruction, disappearance, the destruction of subperiosteum cortex bone etc. all can cause general ostalgia, wherein common with lumbago.Another causes that the major reason of pain is fracture.
2) height shortening, hunchback
In silent middle height, shortening or bow-backed, is one of important clinical sign occurring continue lumbago after, and 5-20 centimetre of height shortening is not sometimes etc.
3) fragility fractures
In osteoporosis, bone fracture threshold reduces significantly, thereby just easily fractured by slight external force.
4) Respiratory Disturbances
Chest, compression fracture of lumbar vertebra due to serious osteoporosis, usually cause humpback, chest deformity, and thoracic cavity capacity obviously declines, and sometimes can cause the changes of function of a plurality of internal organs, and wherein the performance of respiratory system is particularly outstanding.
The final purpose of protect against osteoporosis is to reduce the generation of fracture.Adopt clinically and delay and reduce bone loss, strive for recapturing bone amount, increase bone strength and reach this object.The treatment measure of osteoporosis is divided into basic measure and two aspects of drug therapy.In the measure of basis, bone health replenishers are mainly calcium agent and vitamin D; Drug therapy mainly comprises that anti-bone absorbs the drug, short bone forms medicine and other drug.
Summary of the invention
The object of the present invention is to provide a kind of health food that contains isoflavones.
For achieving the above object, the present invention adopts the component of following weight ratio: 5 parts of resveratrols, 10 parts of isoflavones.
Edible or the pharmaceutic adjuvant that can also add in foregoing invention comprises: diluent, suspending agent, antioxidant, emulsifying agent, disintegrant, binder and anticorrisive agent.
The specific embodiment
Embodiment 1: the health food that contains isoflavones, and its raw material and weight portion are: 5 parts of resveratrols, 10 parts of isoflavones, make capsule, tablet, granule, oral liquid, powder, tea in bag etc.
Embodiment 2: effect Journal of Sex Research
The product that inventor makes the specific embodiment of mentioning in content of the present invention, takes effect comparative studies with calcium agent, below enumerates one group of experimental data wherein.
30 male SD rats are divided into 3 groups by body weight homeostatic principle: low calcium control group, calcium carbonate control group and of the present invention group, each is organized rat ad lib and specially joins accordingly feed.Rat is fed 13 weeks continuously, and after last administration 24 hours, to put to death, separated left side femur, removes skin and flesh, measures the bone density of left side femur.
The impact of the present invention on rat bone density
| Group | Number of animals (only) | Femur mid point bone density (g/cm 2) |
| Low calcium control group | 10 | 0.102±0.009 |
| Calcium carbonate control group | 10 | 0.109±0.010* |
| Of the present invention group | 10 | 0.114±0.013* |
With the comparison of low calcium control group, * P<0.05
Result demonstration, in bone density experiment, with the comparison of low calcium control group, of the present invention group of rat femur quality, calcium content of bone and femur mid point bone density all significantly increase, and show that the present invention has inhibitory action to osteoporosis.
Claims (1)
1. the health food that contains isoflavones, is characterized in that, comprises the component of following weight ratio: 5 parts of resveratrols, 10 parts of isoflavones.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310552672.9A CN103598579A (en) | 2013-11-08 | 2013-11-08 | Health-care food containing soy isoflavone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310552672.9A CN103598579A (en) | 2013-11-08 | 2013-11-08 | Health-care food containing soy isoflavone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103598579A true CN103598579A (en) | 2014-02-26 |
Family
ID=50116893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310552672.9A Pending CN103598579A (en) | 2013-11-08 | 2013-11-08 | Health-care food containing soy isoflavone |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103598579A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1629281A (en) * | 2004-09-01 | 2005-06-22 | 山西林丰实业有限公司 | An ecological white spirit |
| CN1634300A (en) * | 2004-11-05 | 2005-07-06 | 广州国桥医药研究有限公司 | Oral anti-senescence health products |
| CN1680240A (en) * | 2004-04-09 | 2005-10-12 | 汪云 | Composition containing resveratrol and soybean isoflavone and its preparation and use |
| US20090239943A1 (en) * | 2008-03-19 | 2009-09-24 | Sarkar Fazlul H | Nutraceutical composition and methods for its use |
| CN102038126A (en) * | 2010-11-09 | 2011-05-04 | 万光瑞 | Health-care food for regulating blood fat and comprehensively antagonizing atherosclerosis and preparation method thereof |
-
2013
- 2013-11-08 CN CN201310552672.9A patent/CN103598579A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1680240A (en) * | 2004-04-09 | 2005-10-12 | 汪云 | Composition containing resveratrol and soybean isoflavone and its preparation and use |
| CN1629281A (en) * | 2004-09-01 | 2005-06-22 | 山西林丰实业有限公司 | An ecological white spirit |
| CN1634300A (en) * | 2004-11-05 | 2005-07-06 | 广州国桥医药研究有限公司 | Oral anti-senescence health products |
| US20090239943A1 (en) * | 2008-03-19 | 2009-09-24 | Sarkar Fazlul H | Nutraceutical composition and methods for its use |
| CN102038126A (en) * | 2010-11-09 | 2011-05-04 | 万光瑞 | Health-care food for regulating blood fat and comprehensively antagonizing atherosclerosis and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 刘兆平等: "白藜芦醇的生物学作用", 《国外医学.卫生学分册》, vol. 29, no. 03, 31 December 2002 (2002-12-31), pages 146 - 148 * |
| 毕海丹: "白藜芦醇保健医药专利研究进展", 《安徽农业科学》, vol. 39, no. 02, 31 December 2011 (2011-12-31) * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C05 | Deemed withdrawal (patent law before 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140226 |