CN1035956A - Esophagus semipermeable membrane osmotherapy equipment - Google Patents

Esophagus semipermeable membrane osmotherapy equipment Download PDF

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Publication number
CN1035956A
CN1035956A CN 88105271 CN88105271A CN1035956A CN 1035956 A CN1035956 A CN 1035956A CN 88105271 CN88105271 CN 88105271 CN 88105271 A CN88105271 A CN 88105271A CN 1035956 A CN1035956 A CN 1035956A
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CN
China
Prior art keywords
esophagus
semipermeable membrane
sacculus
osmotherapy
main channel
Prior art date
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CN 88105271
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Chinese (zh)
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CN1012260B (en
Inventor
刘津修
王洪贵
刁元浩
王逸民
赵宗慎
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ZOUPING COUNTY HOSPITAL SHANDONG PROV
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ZOUPING COUNTY HOSPITAL SHANDONG PROV
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Publication date
Application filed by ZOUPING COUNTY HOSPITAL SHANDONG PROV filed Critical ZOUPING COUNTY HOSPITAL SHANDONG PROV
Priority to CN 88105271 priority Critical patent/CN1012260B/en
Publication of CN1035956A publication Critical patent/CN1035956A/en
Publication of CN1012260B publication Critical patent/CN1012260B/en
Expired legal-status Critical Current

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  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Esophagus semipermeable membrane osmotherapy equipment has body [2], has on the body [2] to have main channel [17], the wing passage [7] that is used for the medicine injection, the wing passage [16] that is used to extract utricule top esophagus hydrops that is used for nasal feeding, decompression, the tunnel chamber [8] that is used for drain in the body.The sacculus [4] that one semipermeable membrane system is arranged on body [2], metal guide rod [13] are used for cooperating with main channel [17].The present invention utilizes the selective permeation function of semipermeable membrane to implement the topical therapeutic of the esophageal carcinoma, has increased drug effect, has eliminated the misery of operating therapeuticing esophagus cancer and the systemic side effects of chemotherapy, and can treat esophageal fistula and pipeline is narrow.

Description

Esophagus semipermeable membrane osmotherapy equipment
The invention belongs to medical mechanical domain, a kind of more precisely esophagus that places the people can be the sacculus that radial expansible semipermeable membrane is made, the apparatus of diseases such as the enforcement medicine local penetration treatment esophageal carcinoma, esophageal fistula, esophagostenosis by one.
As correlation technique of the present invention, a kind of three lumens are arranged, this apparatus comprises body and two air bags tightening on body.In body, two wing passages and a main channel are arranged, two wing passages communicate with two air bags respectively, and the outer opening of wing passage was sealed by needle stand and cooperating of needle stand plug.This apparatus is to utilize the pneumatophore compressing esophageal wall after inflating to suppress gastrorrhagia or esophagorrhagia.
United States Patent (USP) (it is A61M29100 that the patent No. 4.581,017 is authorized day 1986,4,8 international Patent classificating numbers) has been put down in writing a kind of apparatus of blood vessel dilating.This apparatus comprise both ends open main pipe and on the main pipe, the sacculus installed between the main pipe both ends open; On the main pipe tube wall outside the sacculus two ends a plurality of openings are arranged, the sealing of main pipe and balloon lumen, with the opening of the conjuncted secondary conduit of main pipe in balloon lumen.In the operation, at first make conduit insert blood vessel, and make sacculus be positioned at the angiostenosis place, utilize secondary conduit in sacculus, to fill and force sacculus to be radial outside expansion, narrow blood vessel wall is outwards pushed with liquid.The blood vessel of sacculus both sides is conducted by a plurality of openings and a top end opening on its sidewall by main pipe this moment.
Also retrieve two parts of patent documents promptly with above-mentioned technology is similar: United States Patent (USP) ((11) Patent Number:4,684,363; (45) Date of patent:Aug.4,1987) european patent application ((11) publication number:0183372; (21) Application number:85307528.1)
For the treatment esophageal carcinoma, what present treatment means was commonly used is operation, chemotherapy, three kinds of methods of radiotherapy.Wherein operative treatment is subjected to people's body constitution, age, the course of disease, tumor scope, all multifactor restrictions, and chemotherapy is often brought the systemic side effects of human body.
The objective of the invention is: a kind of new structure of design on the basis of existing three lumens and vasodilation technology, but make the radial expansion of being of its automatic slowly, with the compressing esophageal wall; Can implement the infiltration of medicine, to satisfy the requirement of topical therapeutic; Can solve the discharging of esophagus hydrops on the capsule.Realization by above-mentioned task is used for treating diseases such as the esophageal carcinoma, esophageal fistula and esophagostenosis, improves medical effect, alleviates patient's pain.
The present invention is achieved in that body (2) has three passages, be main channel (17) wing passage (7) and (16), wherein, an end of main channel (17) (placing esophagus one end) sealing has a plurality of open-works (1) on the sidewall of the body (2) of this end.Wing passage (7) and (16) are drawn body (2) by a flexible pipe respectively and are filled in (12), (15) with its sealing by needle stand (11), (14); The other end of wing passage (7) is by external the communicating of several openings (5) with body (2), and the other end of wing passage (16) is then by external the communicating of opening (10) with body (2).The present invention compared with prior art, outstanding characteristics are: be positioned at opening (5) and locate a sacculus made from semipermeable membrane material on body (2).
In order to solve the discharging of hydrops in the sacculus top esophagus in use, the present invention has designed a tunnel chamber (8) in body (2) with on the sacculus opposite position, and tunnel chamber import (9) and tunnel chamber outlet (3) lay respectively at the outside, two ends of sacculus.
Enter position to be treated in the esophagus smoothly for the ease of body (2), the Aided Design that the present invention adopts is: one is with front end (insertion end) sealing of body (2), and the outer surface that will hold is made a smooth sphere; It two is to insert the metal guide rod that there is ball bumps on a top in the main channel (17) of body (2).This guide rod takes out after helping body (2) to enter esophagus.
For prevent sacculus (4) and body (2) when combining because of the external force effect, compressing wing passage (7) and tunnel chamber (8) make its distortion, and the present invention is sleeved on metal ferrules (6) at the corresponding site of body (2) both ends open that bonding or other known method are fixed two metal ferrules (6) sacculus with latex and goes up afterwards and fix.
Figure of description 1 is a structural representation of the present invention;
Figure of description 2 is A-A profiles of accompanying drawing 1;
In the accompanying drawing: the 1st, open-work; The 2nd, body; The 3rd, the outlet of tunnel chamber; The 4th, sacculus; The 5th, opening; The 6th, metal ferrules; The 7th, wing passage; The 8th, the tunnel chamber; The 9th, it is openings that rock is called out  10; The 11st, needle stand; The 12nd, plug; The 13rd, metal guide rod; The 14th, needle stand; The 15th, plug; The 16th, wing passage; The 17th, the main channel.
Introduce in detail embodiment of the present invention below in conjunction with Figure of description: body (2) is made with silastic material, and main channel (17), wing passage (7), (8) four cavitys of wing passage (16) and tunnel chamber are arranged in the body. Wherein, the outer end of the end of main channel (17)-stay oesophagus is unenclosed construction, and the other end of main channel (17) is then by the top closure of body (2). Body (2) top of sealing, its outer surface is a smooth arc surface. Arranging several open-works (1) near the side pipe wall on body (2) top. The clinical effect first of main channel (17) is used for nasal feeding, it two is to reduce pressure for stomach, it three is for the patient who due to illness alters into lemostenosis, for the ease of the importing of body (2), can insert a metal guide rod (13) that spherical top end arranged in main channel (17). Metal guide rod (13) is extracted after body (2) is imported desired area.
Wing passage (7) communicates with the inner chamber of sacculus (4) by the perforate (5) of opening on body (2), and the opening of its other end is positioned at by the flexible pipe top of drawing on the body (2) and by the needle stand that cooperatively interacts (11) and plug (12) sealing and open. Make with semipermeable membrane material with the sacculus (4) that silk thread is tied up and other known method is fixed on the body, the selective permeation performance of utilizing this biological engineering material of pellicle to have, and under certain condition can be voluntarily the slow characteristic of diastole, four effect: a be can receive, utricule and tumor tissues close contact are convenient to, so that infiltrate constantly cancerous tissue by the cancer therapy drug that injects in the wing passage (7), reach the purpose of topical medications, can effectively avoid like this systemic side effects of medicine; B, make tumor tissues be under the balloon compression of radial slow expansion gradually dehydration, atrophy; C, oesophagus played the dilating effect that slowly continues; D, in the treatment to esophageal fistula, the sacculus that pellicle is made (4) can prevent effectively that objective thing enters the thoracic cavity in the oesophagus, and is conducive to the healing of fistula mouth.
Wing passage (16) one ends are through needle stand (14) sealing or the unlatching of flexible pipe by a band plug (15), and the other end is through external the communicating of opening (10) with body (2). The effect of wing passage (16) is that oesophagus endocrine and saliva that sacculus (4) is blocked in oesophagus top are in time extracted out.
Often find that in clinical practice patient is not because in time being extracted out slight illness such as causing cough by the resistance excess secretion in the oesophagus. In order to address this problem, the present invention has designed in the tunnel chamber (8) that body (2) is made. Tunnel chamber import (9) is positioned at the right side (position shown in Figure 1) of sacculus (4); Tunnel chamber outlet (3) is positioned at the left side (position shown in Figure 1) of sacculus (4). Clinical proof: this structure is conducive to saliva and the direct drainage of esophageal secretion enters stomach, can eliminate oesophagus hydrops on the capsule, makes again saliva can enter stomach and participates in digestion, thereby reached and meet physiological hygiene, avoid fluid loss and reduce patient suffering's purpose.
Advantage of the present invention is: rational in infrastructure, be applicable to the cancer of the esophagus, especially late esophagus cancer or the patient that be difficult for to implement operative treatment because of reasons such as age, physique; Alternative operation method treatment esophageal fistula also can be used for treatment and the prevention of fistula and lemostenosis after the oesophagus chemical lesion. Adopt technology of the present invention, eliminated the dangerous of operative treatment and patient's spirit is hit. Clinical practice proves: use the technology of the present invention, and when the concentration of localize cytotoxic medicine can reach systemic administration 50~300 times, and medication is even, and duration of efficacy is long, and systemic side effects is extremely low.
Embodiment:
Select for use silastic material to make body (2), body (2) inserts the end sealing in the esophagus, and the outer surface of this blind end is made spherical smooth surface.On the close body (2) of blind end, there are 10 borders to distribute the open-work (1) that communicates with main channel (17).The opening of main channel (17) is at the end outside the esophagus of staying of body (2).Wing passage (7) crouches and (see accompanying drawing 2) in body (2), one termination of this passage goes out the external of body (2) and is sealed by needle stand (11) and plug (12), the other end extends to the leftward position (shown in Figure 1) of sacculus (4), and wing passage (7) utilizes four openings (5) to communicate with the inner chamber of sacculus (4).Wing passage (16) crouches in body (2), and the one termination goes out body (2) and cooperates sealing by needle stand (14) and plug (15), and its other end extends to the opening (10) on sacculus (4) right side (shown in Figure 1) and locates.
Crouch in body (2) in tunnel chamber (8), its cross-sectional area is greater than wing passage (7) (seeing accompanying drawing 2), and tunnel chamber import (9) is positioned at tying place, sacculus (4) right side, and tunnel chamber outlet (3) is positioned at the left side tying outer (seeing accompanying drawing 1) of sacculus (4).Sacculus adopts semipermeable membrane material to make, and the two-port of sacculus is tightened on the outer wall that is fixed on body (2) with silk thread.The metal guide rod (13) that helps body (7) to enter esophagus is made by steel wire, on the top of metal guide rod (13) a spherical projection is arranged.The other end of metal guide rod bends out the ring-type handle.
The esophagus semipermeable membrane osmotherapy equipment clinic trial of said structure proves: result of use is good.

Claims (5)

1, esophagus semipermeable membrane osmotherapy equipment comprises body [2], and sacculus [4] has main channel [17] in the body [2], wing passage [7] and [16], and the sacculus [4] that it is characterized in that being installed on the body [2] is made with semipermeable membrane material.
2, esophagus semipermeable membrane osmotherapy equipment according to claim 1, it is characterized in that with the corresponding body of sacculus (4) (2) on a tunnel chamber (8) is arranged, tunnel chamber import (9) and tunnel chamber outlet (3) lays respectively at outside the two ends of sacculus (4).
3, esophagus semipermeable membrane osmotherapy equipment according to claim 1 and 2 is characterized in that: body (2) enters the end sealing of esophagus, and the outer wall of this blind end is a smooth sphere.
4, esophagus semipermeable membrane osmotherapy equipment according to claim 1 and 2 is characterized in that: inserting a top in the main channel of body (2) has the metal guide rod of ball bumps (13).
5, esophagus semipermeable membrane osmotherapy equipment according to claim 1 and 2 is characterized in that: on the body (2) at tying place, sacculus (4) two ends a becket (6) is arranged respectively.
CN 88105271 1988-05-18 1988-05-18 Esophagus semipermeable membrane osmotherapy equipment Expired CN1012260B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 88105271 CN1012260B (en) 1988-05-18 1988-05-18 Esophagus semipermeable membrane osmotherapy equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 88105271 CN1012260B (en) 1988-05-18 1988-05-18 Esophagus semipermeable membrane osmotherapy equipment

Publications (2)

Publication Number Publication Date
CN1035956A true CN1035956A (en) 1989-10-04
CN1012260B CN1012260B (en) 1991-04-03

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN 88105271 Expired CN1012260B (en) 1988-05-18 1988-05-18 Esophagus semipermeable membrane osmotherapy equipment

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008154800A1 (en) * 2007-06-20 2008-12-24 Yuanming Luo Multifunctional catheter for detecting respiration and ecg signals
CN103357106A (en) * 2012-04-06 2013-10-23 周军德 Intestinal canal therapy tube

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008154800A1 (en) * 2007-06-20 2008-12-24 Yuanming Luo Multifunctional catheter for detecting respiration and ecg signals
CN103357106A (en) * 2012-04-06 2013-10-23 周军德 Intestinal canal therapy tube
CN103357106B (en) * 2012-04-06 2017-05-10 周军德 Intestinal canal therapy tube

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Publication number Publication date
CN1012260B (en) 1991-04-03

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