CN103592398A - Chromatographic separation method and portable intelligent gas chromatograph based on molecular size - Google Patents
Chromatographic separation method and portable intelligent gas chromatograph based on molecular size Download PDFInfo
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- CN103592398A CN103592398A CN201310168767.0A CN201310168767A CN103592398A CN 103592398 A CN103592398 A CN 103592398A CN 201310168767 A CN201310168767 A CN 201310168767A CN 103592398 A CN103592398 A CN 103592398A
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Abstract
The invention provides a chromatographic separation method and a portable intelligent gas chromatograph based on molecular size. The device not only has analytical abilities of multi-dimensional chromatography, but also employs microelectronic technologies, so that the structure is compact, the energy consumption is decreased greatly, and the device is easy to carry, and therefore the device can be used in occasions which needs on-site sampling analysis, and fast and efficient analysis of complex samples can be carried out. The device is characterized in that a plurality of two-dimensional micro-chromatographic columns are arranged behind a one-dimensional micro-chromatographic column, crucially, intelligent decision systems are arranged between the one-dimensional micro-chromatographic column and the plurality of two-dimensional micro-chromatographic columns behind, the intelligent decision system comprises a information detector and an automatically controlled flow control center, and each group can be in series with the one-dimensional column respectively and completes full two-dimensional model analysis.
Description
Technical field
The present invention relates to a kind of chromatography separating method and portable intelligent gas chromatograph based on molecular size.
Background technology
Gas chromatograph, as the separating tool of complicated organic mixture, has been brought into play very large effect to the compartment analysis of volatile compound.The most of instruments that use are at present one dimension chromatogram, use a pillar, although also can be for containing tens sample analysis to up to a hundred materials,, when sample is more complicated, just makes analysis efficiency and accuracy decline, and there will be the problems such as undetected.As improvement, there is two-dimentional red, orange, green, blue, yellow (ROGBY), the cut from first chromatographic column pre-separation, along seeking successively by sample introduction to the second chromatographic column again, does further separated according to the priority of discharging from first chromatographic column.Although the number of times that can analyze by increase is realized the complete separation to sample, but while entering two-dimensional columns due to outflow one dimension post, the bands of a spectrum of component are wider, therefore, the resolution of the second dimension can incur loss, conventional two-dimensional chromatogram conventionally adopts high-frequency hot modulator cut and compress flowing out the composition of one dimension post between the first peacekeeping two-dimensional columns, and energy consumption is increased.Meanwhile, the capacity of the second dimension separating column of this two-dimensional structure is less, and separating power is limited, can not utilize the advantage of two-dimensional gas chromatography completely, and needs complicated software and calculate and carry out data reconstruction.
Summary of the invention
In order to overcome the deficiency of above-mentioned one dimension chromatogram and two-dimentional chromatogram analysis method, the invention provides a kind of portable intelligent gas chromatograph of the new chromatography separating method based on molecular radius size.This installs the analysis ability of existing multi-dimensional chromatograph, adopts again new material and microelectric technique that its separating power is strengthened, compact conformation, energy consumption significantly declines, be convenient for carrying, thereby can need the occasion that spot sampling is analyzed to use at some, complicated sample is carried out to analysis rapidly and efficiently.Be characterized in using the material that mixed gas can be opened according to molecular radius size discrimination as the first dimension separating column, the material of all molecular radiuss in same magnitude is assigned to same the second dimension chromatographic column and carries out separation.Between the first dimension chromatographic column and a plurality of two-dimentional chromatographic column thereafter, intelligent modulation system is installed.This intelligent modulation system include information detector and (or) modulator and the valve control system of automatically controlling many mouthfuls of solenoid valves.All can connect with one dimension post respectively and complete the analysis of full two-dimensional model for every group.By the information that the first dimension is flowed out, modulate and understand, after contrasting with database data, be automatically assigned to the second suitable dimension chromatographic column and further divide the analysis of variance, thereby complete fast the composition of complex sample and quantitative test.This device is furnished with thin screen electronical display terminal, can read easily analysis result.
Accompanying drawing explanation
Below in conjunction with Fig. 1 and Fig. 2, the present invention will be further described: Fig. 1 is portable intelligent gas chromatograph fundamental diagram, connects a N second dimension detection system form by the first dimension chromatography column.The second dimension detection system consists of decision system and 3 detectors.Fig. 2 is that the structural drawing of decision system (is 3 in Fig. 1
a, 3
b3
n), by control program, molecular sieve and three-port valve door, formed.
As shown in Figure 1, gas sample enters the first dimension chromatographic column (1) and through separation process, enters successively the second dimension detection system (7
ato 7
n).In the second dimension detection system, gas sample is first detected device (2
a) survey the decision system (3 of then flowing through
a).
The structure of decision system as shown in Figure 2, consists of control program (8), molecular sieve (9) and three-port valve door (10).Like this, in decision system (3), sample filters through molecular sieve (9), and molecular radius is greater than molecular sieve, can not pass through, and is left in decision system (3).Shown in Fig. 2 is (3 in Fig. 1
a), (3
b) to (3
n) structure.
Like this, molecular radius is less than molecular sieve, can pass through decision system (3
a) sample be detected device (4
a) survey.When detector (2
a) detect sample and all arrive molecular sieve, and detector (4
a) detect and can pass through decision system (3
a) sample all pass through, the control program in decision system (8) starts the valve (10) in decision system (3), makes to stay decision system (3
a) in gas flow into the second dimension separating column (6
a) middle continuation separation, isolated gas is detected device (5
a) detect successively.Any in the second dimension chromatographic column completes after being assigned with of task, detector (5
a) information is fed back to control program (8), tell it oneself can be assigned with new task, thereby can carry out continuously the automatic analysis of sample.
Embodiment
As an embodiment, the accompanying drawing of still take is illustrated as example:
Sample gas such as petroleum chemicals, complex environment gas etc. enter one dimension chromatographic column (1) and after separation process, enter the second dimension detection system (7 with the carrier gas flowing out
a).In the second dimension detection system (7
a) in, sample is first detected device (2
a) survey, and flow into decision system (3
a), molecular radius is less than decision system (3
a) molecular sieve (9
a) sample by decision system (3
a) flow out, be detected device (4
a) detect, and molecular radius is greater than decision system (3
a) middle molecular sieve (9
a), be left on decision system (3
a) in.When detector (2
a) and (4
a) full recovery is to datum line level (showing not have sample gas to be detected), decision system (3
a) in control software (8
a) open valve (10
a), will stay decision system (3
a) in sample gas be driven into the second dimension chromatographic column (6
a) middle continuation separation, separated sample is detected device (5 successively
a) survey.After having surveyed, detector (5
a) return to the signal surveyed to controlling software (8
a), represent that this second dimension separating column can be assigned with next separated task.By decision system (3
a) sample gas, by decision system (7 below
a) continuation isolated by filtration, its process and decision system (7
a).Decision system
(7
n) molecular sieve radius more and more less,
nlarger molecular radius is less.The thing to be detected of all different molecular radiuses in sample all can be collected to detection like this.
The analysis data that this portable intelligent gas chromatograph obtains also can be by printing with being connected of other peripherals or data transmission etc.
Claims (9)
1. the chromatography separating method based on molecular size and a portable intelligent gas chromatograph, is characterized in that consisting of the miniature chromatographic column of one dimension and the miniature chromatographic column of a plurality of two dimension and decision system and central processing unit and display terminal.
2. chromatography separating method and the portable intelligent gas chromatograph based on molecular size according to claim 1, is characterized in that intelligent system is comprised of control program and molecular sieve and three-port valve door.
3. chromatography separating method and the portable intelligent gas chromatograph based on molecular size according to claim 1, is characterized in that carrier that the miniature chromatographic column of one dimension flows out and sample can enter three-port valve and enter in an orderly manner two-dimentional system through modulation allocation.
4. chromatography separating method and the portable intelligent gas chromatograph based on molecular size according to claim 1, is characterized in that two-dimentional miniature chromatographic column can be one group to many groups.
5. every group all can complete respectively the analysis of full two-dimensional model with coupled in series with one dimension chromatographic column.
6. chromatography separating method and the portable intelligent gas chromatograph based on molecular size according to claim 1, it is characterized in that the information detector in decision system can detect the fluid state information in each stage in multi-dimensional chromatograph analytic process, be converted to valve control action, complete the distribution to the control of the miniature chromatographic column of one dimension and two-dimentional miniature chromatographic column duty.
7. chromatography separating method and the portable intelligent gas chromatograph based on molecular size according to claim 1, after it is characterized in that sample in the miniature chromatographic column of one dimension flows out completely, is attached thereto the valve closing connecing.
8. chromatography separating method and the portable intelligent gas chromatograph based on molecular size according to claim 1, is characterized in that any one miniature chromatographic column of two dimension that has completed two-dimension analysis flow process can enter new round analytical work automatically according to instruction.
9. chromatography separating method and the portable intelligent gas chromatograph based on molecular size according to claim 1, is characterized in that passing through display terminal display analysis result, data and the information that also can obtain by other utility appliance output.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310168767.0A CN103592398A (en) | 2013-05-09 | 2013-05-09 | Chromatographic separation method and portable intelligent gas chromatograph based on molecular size |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310168767.0A CN103592398A (en) | 2013-05-09 | 2013-05-09 | Chromatographic separation method and portable intelligent gas chromatograph based on molecular size |
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| Publication Number | Publication Date |
|---|---|
| CN103592398A true CN103592398A (en) | 2014-02-19 |
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ID=50082621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310168767.0A Pending CN103592398A (en) | 2013-05-09 | 2013-05-09 | Chromatographic separation method and portable intelligent gas chromatograph based on molecular size |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105241984A (en) * | 2015-10-23 | 2016-01-13 | 厦门色谱分析仪器有限公司 | Array multi-dimensional liquid-phase chromatographic column system |
| CN105319304A (en) * | 2015-12-14 | 2016-02-10 | 河南省建筑科学研究院有限公司 | Portable gas chromatograph used for detecting VOC (Volatile Organic Compounds) in indoor air |
-
2013
- 2013-05-09 CN CN201310168767.0A patent/CN103592398A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105241984A (en) * | 2015-10-23 | 2016-01-13 | 厦门色谱分析仪器有限公司 | Array multi-dimensional liquid-phase chromatographic column system |
| CN105319304A (en) * | 2015-12-14 | 2016-02-10 | 河南省建筑科学研究院有限公司 | Portable gas chromatograph used for detecting VOC (Volatile Organic Compounds) in indoor air |
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Application publication date: 20140219 |