CN103584915A - High-performance water cooling microwave ablation antenna integrating real-time temperature measurement and ablation - Google Patents
High-performance water cooling microwave ablation antenna integrating real-time temperature measurement and ablation Download PDFInfo
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- CN103584915A CN103584915A CN201310616794.XA CN201310616794A CN103584915A CN 103584915 A CN103584915 A CN 103584915A CN 201310616794 A CN201310616794 A CN 201310616794A CN 103584915 A CN103584915 A CN 103584915A
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Abstract
The invention provides a high-performance water cooling microwave ablation antenna integrating real-time temperature measurement and ablation. The high-performance water cooling microwave ablation antenna comprises a radiation head, a medium tube, a semi-rigid coaxial cable, an outer guide sleeve, a matching rod and a needle rod. An inner conductor of the semi-rigid coaxial cable penetrates through an inner hole of the outer guide sleeve and an inner hole of the medium tube to be connected with the radiation head, the outer guide sleeve is arranged on the medium tube in a sleeved mode, the matching rod is installed on the outer guide sleeve in a sleeved mode, the needle rod is installed on the matching rod in a sleeved mode, a T-shaped thermocouple temperature measurement end is installed at the butt-joint position of the matching rod and the needle rod, and the outer guide sleeve is in Ohmic contact with an outer conductor of the semi-rigid coaxial cable. Due to the precise and stable open-type antenna structure, the high-performance water cooling microwave ablation antenna is made to have a microwave ablation heat field with high stability, meanwhile, the real-time temperature for ablating tumor tissue can be measured reliably in a contact mode through the temperature measurement end on an antenna body, therefore, the cancel cell inoculation risk which may be caused by using a temperature measurement needle is avoided, and conditions are created and a foundation is laid for microwave ablation intelligentization.
Description
Technical field
The present invention relates to a kind of have real time temperature measurement and the medical apparatus and instruments that melts the high performance water cooling microwave ablation tumor being integrated, belong to medical microwave technical applications.
Background technology
Since entering 21 century, medical microwave technical development is rapid, particularly microwave ablation tumor has developed a kind of Main Means becoming in clinical cancer therapy rapidly, in, tumor fast with its tumor programming rate, temperature is high, ablation range is large, be subject to the outstanding advantages such as carbonization and influence of blood flow be little, at entity tumor, bringing into play more and more important effect in particularly to the treatment of larger entity tumor, the popularity rate of clinical practice is also more and more higher, and range of application has related to the clinical operation of multiple good, the malignant tumor of chest, abdominal part and pelvic cavity.
The feature of Microwave Coagulation Therapy is, under the guiding of the modern images such as B ultrasonic or CT, microwave antenna (needle-like surgical instrument) minimal invasion is got involved in organization internal, by microwave heating effect, causes the physical processes such as cancerous cell heats up rapidly, implements the original position deactivation of tumor.Therefore, for reaching raising curative effect, improve the object of the most basic oncotherapy such as tumor cure rate and raising postoperative rehabilitation level, only also not all right with medical personnel's noble medical ethics and consummate medical skill, also must stablize and superior therapeutic device and the equipment of performance by matching quality, for guarantee is reliably done in microwave ablation operation.
Yet in existing insertion type branch of Wicresoft field, in tumor microwave ablation procedure, the temperature of tumor and measurement---this vital clinical parameter and key technology, does not obtain substantial solution up to now.
As everyone knows, the survival of cell, the healing of focus, the cells such as coagulation necrosis of tumor cell and the pathological change of tissue, after all the variations in temperature that depends on its cell and tissue, and existing clinical in, the result that tumor microwave melts is relied on the images such as B ultrasonic or CT to judge often by veteran doctor, be aided with again from being laid in tumor thermometric needle around and obtain temperature information, draw the conclusion of cancerous cell coagulation necrosis.Clinically, for avoiding inoculation or the transfer of cancerous cell, the thermometric needle of laying is definitely can not encounter cancer cell tissue.In addition, also there is scholar to attempt to carry out thermometric with other indirect modes, but all have no result.
Therefore, the conventional measures that tumor microwave melts clinically is at present, adopt the thermal field scope of microwave ablation enough large, be enough to cover the way of the tumor tissues scale of construction, be intended to put forth effort on " killing " tumor cell, the thermometric problem of avoiding for the time being tumor, the deficiency of avoiding tumor microwave ablating device and equipment, avoids the further investigation of melting relevant clinicing aspect with tumor microwave.
Summary of the invention
The key technology that the present invention solves is: the high performance water cooling microwave ablation antenna body (shank) that utilizes intervention tumour, temperature survey end is installed, thereby in microwave ablation tumor, draw real time temperature and its change information of tumor, propose a kind ofly there is real time temperature measurement and melt the high performance water cooling microwave ablation antenna being integrated.
The present invention has real time temperature measurement and melts the high performance water cooling microwave ablation antenna being integrated, comprise: radiation head, medium tube, half firm coaxial cable, outer bush, shank, described half firm inner conductor packs in radiation head afterbody cylinder blind hole and fixes, described medium tube is assemblied on the afterbody cylinder of radiation head, described outer bush encapsulation is also fixed on the cylinder of medium tube afterbody, the inner wire of described half firm coaxial cable is connected with radiation head passing in the axle center hole of outer bush and medium tube, described outer bush is Ohmic contact with the outer conductor of half firm coaxial cable, it is characterized in that: on described outer bush, encapsulation has the matching stub that radial section size is identical with shank, described matching stub rear end face docks with shank front end face, described matching stub and shank are located and supported by the special bushing pipe that endoporus coordinates with it, special bushing pipe outer surface is provided with two axial notches, in two axial notches, be equipped with respectively temperature measuring wire, the front end melting welding of two temperature measuring wires connects, melting welding place forms spherical fusion points as point for measuring temperature, the outside of described fusion points protrudes from the outer surface of matching stub and shank, fusion points and special bushing pipe, matching stub, shank sealing.
The present invention also has following further improvement:
1, described two temperature measuring wires pass gap between described shank inwall and described special bushing pipe outer surface, and extend to the afterbody of antenna.
2, described matching stub front end encapsulation is on outer bush shoulder cylinder, and is fixed together by welding.
3, the first half para-position of described special bushing pipe cylindrical packs in the hole of matching stub afterbody, and described shank front end encapsulation is on the afterbody cylindrical of special bushing pipe, and matching stub is together with being welded and fixed between shank.
4, the special bushing pipe of described matching stub and shank joint is provided with the concave surface being absorbed in for described fusion points, and described concave surface is communicated with two axial notches of special bushing pipe.
5, described matching stub tail end face offers arc small gap, described shank front end face also offers arc small gap, when matching stub and needle road axis are to after docking, fusion points that encloses to locate and retrain temperature survey end of both arc small gaps by it, the outer surface that matching stub and shank are protruded in the outside of described fusion points is 0.2-0.4 millimeter.
6, the tail end of described two temperature measuring wires is connected and is welded and fixed with Special temperature measurement connector respectively, described special-purpose patchcord terminal soldering is fixed on spacer shell, the link of two temperature measuring wires and patchcord terminal is in antenna body, the other end of described two special-purpose patchcord terminals is outside antenna body, patches connecting line of the same name temperature information is flowed to main process equipment.
7, in the space of half firm coaxial cable and matching stub, special bushing pipe, shank, be installed with 2 water inlet pipes, two water inlet pipe front ends extend apart from outer bush breech face 2-3 millimeter place, and its tail end is directly connected with water inlet tap.
The present invention adopts T-shaped thermocouple temperature measurement technology, its the most outstanding feature is that temperature survey end is that gapless contacts with the tumor cell tissue of microwave ablation, can directly obtain temperature information accurately, its method is reliable, Stability Analysis of Structures, and it is good to have the linearity, the advantage that thermo-electromotive force is larger and highly sensitive.
The front end melting welding of two temperature measuring wires of the present invention connects, and adopts Special Welding Technique, and melting welding place should form spherical fusion points, and fusion points surface should be smooth mellow and full, without burr.
Described in the present invention, weld, all adopt high-temperature soldering technology, recommend and select lead-free high-temperature solder stick, application constant temperature electric iron, or semi-automatic welding, to guarantee that it has enough weld strengths and good conduction, heat conductivility, and without rosin joint phenomenon, air-tightness is good, water-tight, does not seep water.Welding to key position, suggestion adopts Special tooling clamp, or adopts laser weld.
High temperature adhesive of the present invention, recommend adoption single-component epoxy resin glue, as select domestic 6133C one-component thermostable epoxide-resin glue, its feature is that dielectric constant is low, moistureproof and waterproof, and adhesive strength is high and resistance to elevated temperatures is good etc.
The present invention has real time temperature measurement and the prominent features part that melts the high performance water cooling microwave ablation antenna being integrated:
First, by described metal outer bush, be connected with ohm of the outer conductor of half firm coaxial cable, make the opening position of this wire antenna form stable unified precision architecture, for originally melting antenna, provide definite boundary condition, thereby make electromagnetic field distribution and radiation field of aerial that on antenna, field source produces at its surrounding space there is stronger regularity and concordance, make originally to melt antenna and possessed high-performance condition and state.Microwave ablation thermal field scope can be described as abstractively along the ellipse figure in antenna axial direction cross section, as shown in Figure 1 thus.The changing value that experiment showed, the long and short shaft size of microwave thermal field scope is to become the directly proportional functional relationship that property changes according to certain rules with its feed energy, and has good stability, reliability and high efficiency.
The second, in the clinical practice of melting at tumor microwave, feed energy is the microwave power of main frame output and the product of working time.The temperature of microwave ablation tumor coagulation necrosis is determined value, is for example 62 ℃.Clinically, when microwave ablation antenna intervention tumour is organized, the position of the temperature survey end of described matching stub tail end is the marginal position in tumor just, when the tumor temperature of temperature survey end reaches 62 ℃, main frame receives this information, can send immediately instruction: interrupt output microwave power, also can carry out time delay control, now can obtain the corresponding scale of construction of original position deactivation tumor.Under the identical condition of tumor speciality, identical output microwave power and identical working time parameter are set, thereby melting the scale of construction of kitchen range, acquisition tumor microwave will reach unanimity.
The 3rd, the length dimension of matching stub of the present invention, corresponding to the major axis dimension of oval microwave ablation thermal field.For heterogeneity and the different scale of construction of clinical tumor, can select the antenna that melts of different length specification matching stub, shown in Fig. 1, tumor 1 scale of construction is less, can use the shorter specification of its matching stub, as the antenna that melts of point for measuring temperature 1, larger to tumor 2 scale of constructions, can use the longer specification of matching stub, as the antenna that melts of point for measuring temperature 2, by that analogy, tumor 4 scale of constructions are maximum, just use the longest specification of matching stub, as the antenna that melts of point for measuring temperature 4.
The 4th, according to tumor scale of construction size, select the antenna that melts of dimension, can appropriately reach oncotherapy object, both obtained the optimum efficiency of oncotherapy, can prevent again because of main frame feed energy excessive, damage normal structure and occur the serious carbonization of core structure or the phenomenon of coking, cause the unnecessary pain of patient, and affect postoperative rehabilitation.
Five, with same structures such as matching stub and special bushing pipes, can lay multi-point temperature measurement melting on antenna body, contribute to further investigate the relevant issues that tumor microwave melts, as shown in Figure 7.
Six, the cancerous cell inoculation that may bring because of clinical laying bypass thermometric needle or the risk shifting have been evaded.
The present invention has really realized in tumor microwave ablation process, temperature of key part to tumor tissues is measured in real time, thereby actively control tumor microwave ablation surgery, to reaching therapeutic effect and the object of tumour ablation, both be conducive to the healing of cancer and reduced the unnecessary damage of normal cell, and having reduced again patient's pain and be conducive to its postoperative rehabilitation.Meanwhile, for tumor microwave melts intellectuality, create condition, and established the technical foundation of hardware aspect.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, the present invention is further illustrated.
Fig. 1 is that different size matching stub afterbody point for measuring temperature is corresponding to the comprehensive schematic diagram that melts different scale of construction tumors.
Fig. 2 is the front-end architecture schematic diagram of the embodiment of the present invention one.
Fig. 3 is the A-A portion view of Fig. 2.
Fig. 4 is the B enlarged diagram of Fig. 2.
Fig. 5 is the tail structure schematic diagram of the embodiment of the present invention one.
Fig. 6 is portion's view of Fig. 5.
Fig. 7 is the front-end architecture schematic diagram of the embodiment of the present invention two.
Fig. 8 is the tail structure schematic diagram of the embodiment of the present invention two.
Label in figure is schematically as follows: 1-radiation head, 2-medium tube, 3-half is coaxial cable just, 4-outer bush, 5-shank, 6-inner conduit, 7-shank positioning sleeve, 8-spacer shell, 9-radio frequency contact pin connector, 10-handle tail, 11-water inlet tap, 12-faucet, 13-Hafu-type handle body, 14-pommel, 15-matching stub, the special bushing pipe of 16-, 17-fine copper silk temperature measuring wire, 18-Contra wire temperature measuring wire, the special-purpose patchcord terminal of 19-, 20-terminal base, the 15 '-the second matching stub, the 16 '-the second special bushing pipe, the 17 '-the second fine copper silk temperature measuring wire, the 18 '-the second Contra wire temperature measuring wire, the 19 '-the second special-purpose patchcord terminal.
The specific embodiment
Embodiment mono-
As shown in Fig. 2, Fig. 3, Fig. 4, Fig. 5, Fig. 6, be that the present embodiment has real time temperature measurement and melts the high performance water cooling microwave ablation antenna being integrated, its composition comprises: radiation head 1, medium tube 2, half firm coaxial cable 3, outer bush 4, shank 5, water inlet pipe 6, shank positioning sleeve 7, spacer shell 8, radio frequency contact pin connector 9, handle tail 10, water inlet tap 11, faucet 12, Hafu-type handle body 13, pommel 14, matching stub 15, special bushing pipe 16, fine copper silk temperature measuring wire 17, Contra wire temperature measuring wire 18, special-purpose patchcord terminal 19, terminal base 20.
Be illustrated in figure 2 the front-end architecture of the present embodiment, the half cylindrical blind hole of afterbody that just inner wire of coaxial cable 3 has packed radiation head 1 into adopts to weld and be aided with gets riveting ready, is fixed.Medium tube 2 is assemblied on the afterbody cylinder of radiation head 1, is coated with bonding agent and fixes.Outer bush 4 encapsulations, on the shoulder cylindrical of medium tube 2, press and are aided with bonding agent with multiple spot mechanical force and fix, and the axle center hole encapsulation of outer bush 4 is on the outer conductor of half firm coaxial cable 3, to be welded and fixed simultaneously.The front end endoporus encapsulation of matching stub 15 is on outer bush 4 shoulder cylindricals, and employing is welded and fixed.Special bushing pipe 16 front end cylindrical para-positions pack matching stub 15 afterbody endoporus into, require the arc small gap on spherical pit para-position matching stub 15 breech faces of special bushing pipe 16 outer surfaces, then welding location.The fusion points of T-shaped electric thermo-couple temperature measuring junction is arranged in the concave surface of special bushing pipe 16 outer round surface, and two temperature measuring wires 17,18 are placed in respectively in axial two grooves of special bushing pipe 16, and its tail end extends to antenna afterbody.Shank 5 front end endoporus are inserted in from the tail end of two temperature measuring wires 17,18, para-position is assemblied on special bushing pipe 16 cylindricals, the arc small gap of shank 5 front end faces docks with the arc small gap para-position of matching stub 15 breech faces, its breach encloses rear constraint and is controlling the radial variable of fusion points, the outer surface that makes the sphere top, outside of fusion points protrude from matching stub and shank is 0.2-0.4 millimeter, as shown in Figure 4.Matching stub 15 is connected place, gap with the axial para-position of shank 5, adopt welding or laser weld firm, and the reliable air-tightness of tool.Two water inlet pipes 6 put in from the tail end of shank 5, and its front end is about 2-3 millimeter apart from the tail end of outer bush 4.
Emphasis shown in Fig. 3 is half just coaxial cable 3, two water inlet pipes 6, special bushing pipe 16 and fine copper silk temperature measuring wires 17, the position relationship of Contra wire temperature measuring wire 18 in shank 5.
Fig. 4 is part section enlarged drawing, it is the specification requirement of 0.2-0.4 millimeter that emphasis has been described the outer surface that sphere top outside the fusion points of temperature survey end protrudes from matching stub 15 and shank 5, and after 5 docking of matching stub 15 and shank, the interior large outer little internal conical surface body that encloses formation by its both ends of the surface arc small gap retrains and locates the position of thermometric fusion points.
Figure 5 shows that the tail structure of the present embodiment.Wherein, on terminal base 20, be welded and fixed the spare parts such as radio frequency contact pin connector 9, water inlet tap 11 and two special-purpose patchcord terminals 19, correspondingly be welded and fixed respectively half just coaxial cable 3, two water inlet pipes 6 and fine copper silk temperature measuring wire 17, Contra wire temperature measuring wire 18, on terminal base 20, be also welded and fixed faucet 12.Spacer shell 8 endoporus encapsulations are on the shoulder cylindrical of terminal base 20, and to be welded and fixed, shank positioning sleeve 7 tail end shoulder cylindricals push the end face inner bore of spacer shell 8, and to be welded and fixed, its endoporus and shank 5 cylindricals are to be welded and fixed.Thus, shank positioning sleeve 7, spacer shell 8 and terminal base 20 form the backwater cavity that originally melts antenna, and cooling water flows out outside antenna body from the faucet 12 being welded on terminal base 20 again.
The straight handle type operating grip being formed by pommel 14, Hafu-type handle body 13 and handle tail 10 in the periphery of antenna body afterbody backwater cavity.Structurally, the shoulder of the interior semicircle orifice by the 13 two ends indentations of Hafu-type handle body is stuck in the outer face of shank positioning sleeve 7 and terminal base 20, retrain the degree of freedom of antenna body, being aided with gluing fixes, then pommel 14 and handle tail 10 difference encapsulations are at the two ends of Hafu-type handle body 13 shoulder cylindricals, to be adhesively fixed.
Figure 6 shows that the cutaway view of the present embodiment afterbody, expressed the radio frequency contact pin connector 9, water inlet tap 11, faucet 12 and two the special-purpose patchcord terminals 19 that on terminal base 20 parts, are welding mutually at position relationship
The present embodiment has the thermometric of enforcement and melts the high performance water cooling microwave ablation antenna being integrated, and its assemble flow is first assembled, is then general assembly.The assembled of the present embodiment has:
1, by outer bush 4 encapsulations on the shoulder cylindrical of medium tube 2, on both composition surfaces, be coated with bonding agent, use Specific Clamps, in the annular groove position of the shoulder cylindrical with respect to medium tube 2, imposing multiple spot mechanical force presses, so that outer bush 4 inwalls produce convex distortion, form " the medium tube assembly " that be fastenedly connected.
2, by two water inlet pipes 6 of technique length intercepting, then be welded and fixed as " water inlet component " with water inlet tap 12.
3, by the specification requirement of temperature survey end (fusion points), welding fine copper silk temperature measuring wire 17 and Contra wire temperature measuring wire 18, or T-shaped thermocouple and the temperature survey end thereof of the customization of check special manufacturer.
4, the spare part such as wielding neck fixed RF contact pin connector 9, water inlet tap 11 (water inlet component), faucet 12 and two special-purpose patchcord terminals 19 on terminal base 20, forms by " terminal base assembly ".
After completing above assembled, according to first fore-end again the order of afterbody carry out general assembly:
First the inner wire of half firm coaxial cable 3 is packed in the cylindrical blind hole of afterbody of radiation head 1, to weld and to be aided with, get riveting ready, fixed.Outer conductor surface cover by " medium tube assembly " along half firm coaxial cable 3 is filled on the afterbody cylinder of radiation head 1, should be coated with bonding agent at the afterbody periphery of irradiator 1 in advance, outer conductor junction to the axle center hole tail end of outer bush 4 and coaxial cable 3, to be welded and fixed.
Again the front end endoporus encapsulation of matching stub 15 is led on 4 shoulder cylindricals, to be welded and fixed outside.
Pack special bushing pipe 16 front end cylindrical para-positions into matching stub 15 afterbody endoporus, require the spherical concave surface of special bushing pipe 16 outer surfaces and the arc small gap para-position on matching stub 15 breech faces, then with welding location.
The fusion points of T-shaped electric thermo-couple temperature measuring junction is arranged in the hemispherical concave surface of special bushing pipe 16 outer round surface, take advantage of a situation two temperature measuring wires 17,18 are placed in respectively in axial two grooves of special bushing pipe 16, its tail end extends to antenna afterbody, requires two temperature measuring wires, 17,18 outer round surface lower than the outer round surface of special bushing pipe 16.
Shank 5 front end endoporus pack into from half firm coaxial cable 3 and two temperature measuring wire 17,18 tail ends, by its encapsulation on special bushing pipe 16 cylindricals, the arc small gap of shank 5 front end faces docks with the arc small gap para-position of matching stub 15 breech faces, its breach encloses rear constraint and is controlling the radial variable of fusion points, and the outer surface that requires the sphere top, outside of fusion points to protrude from matching stub 15 and shank 5 is 0.2-0.4 millimeter.
Matching stub 15 is connected with the axial para-position of shank 5, adopts welding or laser weld, makes it to be connected firmly and to have air-tightness.
After completing the assembling of the present embodiment fore-end, leak detection and the check of the aspects such as air-tightness and sensitivity of thermometry, bonding strength carried out in suggestion, then carries out the assembling of the present embodiment afterbody, and flow process is as follows:
First by two water inlet pipes 6 along shank 5 inner hole walls, and and half just the space between coaxial cable 3 pack in shank 5, then by the half firm inner and outer conductor of coaxial cable 3 and the inner and outer conductor of radio frequency contact pin connector 9, firm by specification requirement wielding neck, again fine copper silk temperature measuring wire 17 and Contra wire temperature measuring wire 18 are distinguished to wielding necks at special-purpose patchcord terminal 19, complete thus the assembly connection of the present embodiment front-end architecture part and " terminal base assembly ".
Then, by spacer shell 8 tail end endoporus encapsulations on terminal base 20 end face shoulder cylindricals, with firm welding, again shank positioning sleeve 7 is axially packed into from the outer surface of antenna front end edge shank 5, its end face shoulder cylindrical is pushed to the end face inner bore of spacer shell 8, after putting in place, be welded and fixed, shank positioning sleeve 7 endoporus and shank 5 cylindricals, then to be welded and fixed.
More than complete the assembling of the present embodiment antenna body part.In above-mentioned assembling process, all requirement welding parts, all adopt high temperature stannum wire bond to connect, and must not have rosin joint phenomenon, and all weld seams must not leak or seep water; Allly require bondingly, recommend high temperature adhesive, and undertaken by its technique for sticking requirement.
As " melting antenna body " semi-finished product, should carry out the check of properties of product and technical specification at this point, can be according to the regulation of national pharmaceuticals industry standard and requirement, full inspection is taked in suggestion.
Finally gummed or heat seal plastic handle.First the para-position of antenna body afterbody is packed in Hafu-type handle body 13, gluing is fixed, then glues together second half Hafu-type handle body 13, gluing then, by pommel 14 and handle tail 10 respectively encapsulations at Hafu-type handle body 13, end to end on the shoulder cylindrical at two ends, with gluing, fix.At this point, finish the assembling of the present embodiment.
After this examination and test of products, GB2828 sampling inspection is carried out in suggestion.
Embodiment bis-
As Fig. 7, shown in Fig. 8, be that the present embodiment has real time temperature measurement and melts the high performance water cooling microwave ablation antenna being integrated, its composition comprises: radiation head 1, medium tube 2, half firm coaxial cable 3, outer bush 4, shank 5, water inlet pipe 6, shank positioning sleeve 7, spacer shell 8, radio frequency contact pin connector 9, handle tail 10, water inlet tap 11, faucet 12, Hafu-type handle body 13, pommel 14, matching stub 15, special bushing pipe 16, fine copper silk temperature measuring wire 17, Contra wire temperature measuring wire 18, special-purpose patchcord terminal 19, the second matching stub 15 ', the second special bushing pipe 16 ', the second fine copper silk temperature measuring wire 17 ', the second Contra wire temperature measuring wire 18 ', the second special-purpose patchcord terminal 19 '.
The present embodiment and embodiment mono-mainly contain 2 different:
1, the present embodiment has increased a set of T-shaped thermocouple temperature measuring apparatus.According to clinical needs, structurally can increase auxiliary point for measuring temperature, as for the crucial controlled temperature of microwave ablation, should be defined as the temperature of that point for measuring temperature in borderline tumor.Because melt under normal circumstances at tumor microwave, the closer to microwave ablation center, the temperature of tumor is just higher, and for example melting kitchen range is 5 centimetres of above in vitro Hepar Sus domesticas, and it melts central temperature can surpass 100 ℃, reaches more than 120 ℃.
2, the present embodiment handle profile is pistol handle style.
Be illustrated in figure 7 the front-end architecture of the present embodiment.With embodiment mono-difference, it is exactly the place ahead at a T-shaped electric thermo-couple temperature measuring junction, near the position of melting center, increased by the second temperature survey end, increased one group of part that speciality is identical: the special bushing pipe 16 ' of the second matching stub 15 ', second, the second fine copper silk temperature measuring wire 17 ' and the second Contra wire temperature measuring wire 18 '.
Be illustrated in figure 8 the tail structure of the present embodiment.Wherein, on spacer shell 8, be welded and fixed the spare parts such as water inlet tap 11, two special-purpose patchcord terminals 19 and two the second special-purpose patchcord terminals 19 ', correspondence is being welded the parts such as two water inlet pipes 6, fine copper silk temperature measuring wire 17, Contra wire temperature measuring wire 18 and the second fine copper silk temperature measuring wire 17 ', the second Contra wire temperature measuring wire 18 ' respectively with it, on this external spacer shell 8, is also being welded and fixed faucet 12.Half firm coaxial cable 3 directly docks with radio frequency contact pin connector 9, to be welded and fixed.Spacer shell 8 tail end endoporus encapsulations are on the cylindrical of the horizontal end face shoulder of radio frequency contact pin connector 9, with firm welding.Shank positioning sleeve 7 tail end shoulder cylindricals pack in the endoporus of spacer shell 8 end faces, and to be welded and fixed, its endoporus and shank 5 cylindricals are to be welded and fixed.Like this, shank positioning sleeve 7, spacer shell 8 and radio frequency contact pin connector 9 assembly weldings form backwater cavity, and cooling water can flow out outside antenna body from the faucet 12 being welded on spacer shell 8.
The pistol shank type operating grip that antenna body afterbody is comprised of pommel 14, Hafu-type handle body 13 and handle tail 10.Structurally, by necking down endoporus and the afterbody block of Hafu-type handle body 13 front end-stopping plates, retraining the degree of freedom of antenna body, be aided with gluing and fix, is then that pommel 14 and handle tail 10 difference encapsulations are at the two ends of Hafu-type handle body 13 shoulder cylindricals, to be adhesively fixed.
The present embodiment has to be implemented thermometric and melts the high performance water cooling microwave ablation antenna being integrated, and its assemble flow is assembled in advance, then carries out general assembly:
Identical with embodiment mono-, first carry out " medium tube assembly " assembling.
By two water inlet pipes 6 of technique length intercepting, then be welded and fixed as " water inlet component " with water inlet tap 12.
By the specification requirement of temperature survey end (fusion points), welding fine copper silk temperature measuring wire 17 and Contra wire temperature measuring wire 18, welding welding fine copper silk temperature measuring wire 17 ' and Contra wire temperature measuring wire 18 ', the fusion points of the temperature survey end of two groups of T thermocouples, or T-shaped thermocouple and the temperature survey end thereof of the customization of check specialized factory.
Fixedly water inlet tap 11 (water inlet component), faucet 12 of wielding neck on spacer shell 8, forms by " spacer shell assembly ".
After completing above assembled, also by first fore-end again the order of afterbody carry out general assembly:
The assemble sequence of the present embodiment fore-end and requirement and embodiment's mono-is basic identical, is not repeated.Its difference is: the present embodiment is in the place ahead of the T-shaped electric thermo-couple temperature measuring junction of embodiment mono-, be close to the position of melting center and increased again a temperature survey end, therefore increased one group of part that speciality is identical: the special bushing pipe 16 ' of the second matching stub 15 ', second, the second fine copper silk temperature measuring wire 17 ' and the second Contra wire temperature measuring wire 18 ', therefore, the corresponding part that in the present embodiment, two groups of speciality are identical is in full accord with the assembling main points of each corresponding part of embodiment mono-and matching requirements etc., therefore be also not repeated.
After completing the assembling of the present embodiment fore-end, leak detection and the check of the aspects such as air-tightness and sensitivity of thermometry, bonding strength carried out in suggestion.Then enter the assemble flow of the present embodiment afterbody, order is as follows:
First by two water inlet pipes 6 along shank 5 inner hole walls, and and half just the space between coaxial cable 3 pack in shank 5.By the half firm inner and outer conductor of coaxial cable 3 and the inner and outer conductor of radio frequency contact pin connector 9, firm by specification requirement wielding neck again.By fine copper silk temperature measuring wire 17, Contra wire temperature measuring wire 18, the second fine copper silk temperature measuring wire 17 ', the tail end of four temperature measuring wires such as the second Contra wire temperature measuring wire 18 ' respectively para-position passes from the installing hole of each special-purpose patchcord terminal of spacer shell 8, then distinguish the heart yearn firm welding of para-position and each self-corresponding special-purpose patchcord terminal 19 (two) and the second special-purpose patchcord terminal 19 ' (two), then special-purpose patchcord terminal 19 and the second special-purpose patchcord terminal 19 ' are packed into the installing hole separately of spacer shell 8, by the shoulder cylindrical of each special-purpose patchcord terminal and each installing hole of spacer shell 8, locate, then be welded and fixed.Then by the shoulder endoporus encapsulation of spacer shell 8 tail ends on the cylindrical of the horizontal end face shoulder of radio frequency contact pin connector 9, to be welded and fixed.Again shank positioning sleeve 7 is axially packed into from the outer surface of antenna front end edge shank 5, its end face shoulder cylindrical is packed into the end face inner bore of spacer shell 8, after putting in place, be welded and fixed, shank positioning sleeve 7 endoporus and shank 5 cylindricals, then to be welded and fixed.
More than complete the assembling of the present embodiment antenna body part.In above-mentioned assembling process, all requirement welding parts, all adopt high temperature stannum wire bond to connect, and must not have rosin joint phenomenon, and all weld seams must not leak or seep water.Allly require bondingly, recommend high temperature adhesive, and undertaken by its technique for sticking requirement.
As " melting antenna body " semi-finished product, should carry out the check of properties of product and technical specification at this point, can be according to the regulation of national pharmaceuticals industry standard and requirement, full inspection is taked in suggestion.
Finally gummed or heat seal plastic handle.First the backwater cavity part para-position of antenna body afterbody is installed in Hafu-type handle body 13, gluing is fixed, then glues together second half Hafu-type handle body 13, then gluing, by pommel 14 and handle tail 10 respectively encapsulations at Hafu-type handle body 13, end to end on the shoulder cylindrical at two ends, with gluing, fix.
At this point, finish the assembling of the present embodiment.After this, GB2828 sampling inspection is carried out in examination and test of products suggestion.
From exemplar assembling and the experimental result of embodiment, show, the present invention has the microwave ablation thermal field compared with high stability, simultaneously by the temperature survey end of the T-shaped thermocouple on antenna body, can directly obtain the real time temperature of ablated tumor tissue, have temperature data reliable, highly sensitive, the linearity is good, the advantage that thermo-electromotive force is larger, realizes and has reached real time temperature measurement and the hope and the object that melt the clinical tumor Microwave Coagulation Therapy that is integrated.
The present invention has not only reduced patient's misery, and evaded the risk of using the cancerous cell inoculation that thermometric needle may cause, particularly the tumor temperature under clinical treatment state accurately measures, contribute to actively to control tumor microwave ablation surgery process, for condition has been created in Microwave Coagulation Therapy intellectuality, and established the technical foundation of hardware aspect.
In addition to the implementation, the present invention can also have other embodiments.All employings are equal to the technical scheme of replacement or equivalent transformation formation, all drop on the protection domain of requirement of the present invention.
Claims (8)
1. there is real time temperature measurement and melt the high performance water cooling microwave ablation antenna being integrated, comprise: radiation head, medium tube, half firm coaxial cable, outer bush, shank, described half firm inner conductor packs in radiation head afterbody cylinder blind hole and fixes, described medium tube is assemblied on the afterbody cylinder of radiation head, described outer bush encapsulation is also fixed on the cylinder of medium tube afterbody, the inner wire of described half firm coaxial cable is connected with radiation head passing in the axle center hole of outer bush and medium tube, described outer bush is Ohmic contact with the outer conductor of half firm coaxial cable, it is characterized in that: on described outer bush, encapsulation has the matching stub that radial section size is identical with shank, described matching stub rear end face docks with shank front end face, described matching stub and shank are located and supported by the special bushing pipe that endoporus coordinates with it, special bushing pipe outer surface is provided with two axial notches, in two axial notches, be equipped with respectively temperature measuring wire, the front end melting welding of two temperature measuring wires connects, melting welding place forms spherical fusion points as point for measuring temperature, the outside of described fusion points protrudes from the outer surface of matching stub and shank, fusion points and special bushing pipe, matching stub, shank sealing.
2. according to claim 1 have real time temperature measurement and melt the high performance water cooling microwave ablation antenna being integrated, it is characterized in that: described two temperature measuring wires pass gap between described shank inwall and described special bushing pipe outer surface, and extend to the afterbody of antenna.
3. according to claim 1 have real time temperature measurement and melt the high performance water cooling microwave ablation antenna being integrated, and it is characterized in that: described matching stub front end encapsulation, on outer bush shoulder cylinder, and is fixed together by welding.
4. according to claim 1 have real time temperature measurement and melt the high performance water cooling microwave ablation antenna being integrated, it is characterized in that: the first half para-position of described special bushing pipe cylindrical packs in the hole of matching stub afterbody, described shank front end encapsulation is on the afterbody cylindrical of special bushing pipe, and matching stub is together with being welded and fixed between shank.
5. according to claim 1 have real time temperature measurement and melt the high performance water cooling microwave ablation antenna being integrated, it is characterized in that: the special bushing pipe of described matching stub and shank joint is provided with the concave surface being absorbed in for described fusion points, and described concave surface is communicated with two axial notches of special bushing pipe.
6. according to claim 5 have real time temperature measurement and melt the high performance water cooling microwave ablation antenna being integrated, it is characterized in that: described matching stub tail end face offers arc small gap, described shank front end face also offers arc small gap, when matching stub and needle road axis are to after docking, fusion points that encloses to locate and retrain temperature survey end of both arc small gaps by it, the outer surface that matching stub and shank are protruded in the outside of described fusion points is 0.2-0.4 millimeter.
7. according to claim 1 have real time temperature measurement and melt the high performance water cooling microwave ablation antenna being integrated, it is characterized in that: the tail end of described two temperature measuring wires is connected and is welded and fixed with Special temperature measurement connector respectively, described special-purpose patchcord terminal soldering is fixed on spacer shell, the link of two temperature measuring wires and patchcord terminal is in antenna body, the other end of described two special-purpose patchcord terminals is outside antenna body, patches connecting line of the same name temperature information is flowed to main process equipment.
8. according to claim 1 have real time temperature measurement and melt the high performance water cooling microwave ablation antenna being integrated, it is characterized in that: in the space of half firm coaxial cable and matching stub, special bushing pipe, shank, be installed with 2 water inlet pipes, two water inlet pipe front ends extend apart from outer bush breech face 2-3 millimeter place, and its tail end is directly connected with water inlet tap.
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| CN201310616794.XA CN103584915A (en) | 2013-11-29 | 2013-11-29 | High-performance water cooling microwave ablation antenna integrating real-time temperature measurement and ablation |
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| CN106166088A (en) * | 2016-08-08 | 2016-11-30 | 杨兴瑞 | Anti-microwave interference thermometric with melt integral type high performance water cooling microwave ablation antenna |
| CN108565653A (en) * | 2018-04-04 | 2018-09-21 | 江苏华吉通信科技有限公司 | High voltage bearing radio frequency (RF) coaxial connector contact pin |
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