CN103563943A - Sterilizing compound containing bromuconazole and methoxyl acrylic ester - Google Patents
Sterilizing compound containing bromuconazole and methoxyl acrylic ester Download PDFInfo
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Abstract
The invention discloses a sterilizing compound containing bromuconazole and methoxyl acrylic ester. The sterilizing compound comprises active components A and B, wherein the active component A is bromuconazole, and the active component B can be any one of the following compounds: azoxystrobin, pyraclostrobin, benzene kresoxim-methyl, enestroburin, kresoxim methyl, orysastrobin, metominostrobin and pyraoxystrobin, and the mass ratio of the active components A and B is 1:80-80:1. The compound disclosed by the invention has a synergic effect on various diseases harmful to agricultural production, the pesticide dose is reduced, the residual amount of pesticide on crops is reduced and the environmental pollution is reduced. The sterilizing compound is safe to human and livestock and good in environmental compatibility, and resistance to drugs is not easy to generate for the diseases.
Description
Technical field
The invention belongs to technical field of pesticide, relate to the application of a kind of bactericidal composition containing bromuconazole and methoxy acrylic on corps diseases.
Background technology
Bromuconazole (bromuconazole) chemical name: 1-((2RS, 4RS; 2RS, 4RS) the bromo-2-(2 of-4-, 4-dichlorophenyl-) tetrahydrofurfuryl)-1H-1,2,4-triazole, bromuconazole can be prevented and treated Ascomycetes, Basidiomycetes and the Fungi Imperfecti pathogen on cereal crop, grape, fruit tree and vegetables effectively.In addition, also effective to Alternaria and Fusarium pathogen.
Fluoxastrobin, pyraclostrobin, ZJ0712, Enestroburin, kresoxim-methyl, orysastrobin, SSF 126, azoles bacterium ester all belong to the bactericidal composition of methoxy acrylic, are widely used in the disease of crops.
Yet in the real process of agricultural production, preventing and treating the problem that disease the most easily produces is the generation of disease drug resistance.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect very obviously, co-toxicity coefficient very high composite just still less.Through inventor's research, after discovery is composite by bromuconazole and Fluoxastrobin, pyraclostrobin, ZJ0712, Enestroburin, kresoxim-methyl, orysastrobin, SSF 126, azoles bacterium ester, can produce good synergistic effect, and not yet open about the composite relevant report of bromuconazole and Fluoxastrobin, pyraclostrobin, ZJ0712, Enestroburin, kresoxim-methyl, orysastrobin, SSF 126, azoles bacterium ester.
Summary of the invention
The object of the invention is to propose a kind of have synergistic function, use cost is low, preventive effect the is good bactericidal composition containing bromuconazole and methoxy acrylic.
The bactericidal composition containing bromuconazole and methoxy acrylic that the present invention proposes contains active components A and active component B, active components A and active component B weight ratio are 1 ︰ 80 ~ 80 ︰ 1, described active components A is selected from bromuconazole, active component B is selected from a kind of in Fluoxastrobin, pyraclostrobin, ZJ0712, Enestroburin, kresoxim-methyl, orysastrobin, SSF 126, azoles bacterium ester, and active components A and the preferred weight ratio of active component B are 1 ︰ 60 ~ 60 ︰ 1; More preferably the weight ratio of bromuconazole and Fluoxastrobin is 1 ︰ 30 ~ 15 ︰ 1, the weight ratio of bromuconazole and pyraclostrobin is 1 ︰ 30 ~ 30 ︰ 1, the weight ratio of bromuconazole and ZJ0712 is 1 ︰ 15 ~ 30 ︰ 1, the weight ratio of bromuconazole and Enestroburin is 1 ︰ 30 ~ 30 ︰ 1, the weight ratio of bromuconazole and kresoxim-methyl is 1 ︰ 30 ~ 30 ︰ 1, the weight ratio of bromuconazole and orysastrobin is 1 ︰ 30 ~ 30 ︰ 1, the weight ratio of bromuconazole and SSF 126 is 1 ︰ 30 ~ 15 ︰ 1, and the weight ratio of bromuconazole and azoles bacterium ester is 1 ︰ 30 ~ 30 ︰ 1; The weight ratio that most preferably is bromuconazole and Fluoxastrobin is 1 ︰ 10 ~ 5 ︰ 1, the weight ratio of bromuconazole and pyraclostrobin is 1 ︰ 10 ~ 10 ︰ 1, the weight ratio of bromuconazole and ZJ0712 is 1 ︰ 1 ~ 10 ︰ 1, the weight ratio of bromuconazole and Enestroburin is 1 ︰ 10 ~ 10 ︰ 1, the weight ratio of bromuconazole and kresoxim-methyl is 1 ︰ 10 ~ 10 ︰ 1, the weight ratio of bromuconazole and orysastrobin is 1 ︰ 10 ~ 10 ︰ 1, the weight ratio of bromuconazole and SSF 126 is 1 ︰ 10 ~ 1 ︰ 1, and the weight ratio of bromuconazole and azoles bacterium ester is 1 ︰ 10 ~ 10 ︰ 1.
Bactericidal composition containing bromuconazole and methoxy acrylic of the present invention is for preventing and treating the purposes of disease on crops, and described crops comprise cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flowers crop, medicinal crop, raw material crop, green manure pasture crop; Described disease comprises powdery mildew, downy mildew, peronospora tabacina, scab, rust, epidemic disease, rice blast, banded sclerotial blight, shot hole, anthracnose, brown spot, leaf spot, net blotch, spike rot, glume blight.
The weight ratio of active components A, active component B is 1 ︰ 80 ~ 80 ︰ 1.Conventionally in composition, the weight percentage of active component is gross weight 0.1%～90%, is preferably 5%～70%.According to different preparation types, active component content scope is different.Conventionally, liquid preparation contains 1%～70% active substance by weight, is preferably 5%～50%; Solid pharmaceutical preparation contains 5%～70% active substance by weight, is preferably 10%～70%.
In bactericidal composition of the present invention, at least contain a kind of surfactant, the dispersion of active component in water while being beneficial to use.Surface-active contents is 5%～30% of total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, binding agent or defoamer.According to different dosage form, in preparation, can also contain disintegrant known in those skilled in the art, antifreeze etc.
Bactericidal composition of the present invention can be by user before use through dilution or directly use.Its preparation can be prepared by common processing method known in those skilled in the art, after being about to active substance and mixing with liquid flux or solid carrier, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer etc.
Bactericidal composition of the present invention, can be processed on demand acceptable formulation on any agricultural chemicals, wherein more preferably formulation is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspending agent.
When making wetting powder, composition comprises following constituent content: active components A 1% ~ 80%, active component B1% ~ 80%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, filler surplus.
When making water dispersible granules, composition comprises following constituent content: active components A 1% ~ 80%, active component B1% ~ 80%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
When making suspending agent, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
When making suspension emulsion, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, defoamer 0.01% ~ 2%, solvent 1% ~ 15%, thickener 0 ~ 2%, emulsifier 2% ~ 12%, antifreeze 0 ~ 8%, deionized water add to 100%.
When making aqueous emulsion, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 1% ~ 15%, antifreeze 0 ~ 8%, thickener 0 ~ 2%, defoamer 0.01% ~ 2%, deionized water are supplied surplus.
When making microemulsion, composition comprises following component and content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, emulsifier 3% ~ 25%, solvent 1% ~ 10%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water add to 100%.
When making microcapsule suspending agent, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 10%, organic solvent 1% ~ 10%, emulsifier 1% ~ 7%, defoamer 0.01% ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
When making microcapsule suspension-suspending agent, composition comprises following constituent content: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, organic solvent 1% ~ 15%, emulsifier 1% ~ 6%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspending agent the key technical indexes of the present invention:
The invention has the advantages that:
(1) bromuconazole and Fluoxastrobin, pyraclostrobin, ZJ0712, Enestroburin, kresoxim-methyl, orysastrobin, SSF 126, azoles bacterium ester composite after, there is obvious synergy and lasting effect; (2) disease on cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flowers crop, medicinal crop, raw material crop, green manure pasture crop is all had to greater activity; (3) reduce agricultural chemicals dosage, reduced the residual quantity of agricultural chemicals on crop, alleviated environmental pollution; (4), to person poultry safety, Environmental compatibility is good; And preparation adhesion strength strengthens, resistance of rainwater washing against.
Embodiment
Below in conjunction with embodiment, to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Example 1～18 wetting powder
Bromuconazole, active component B, dispersant, wetting agent, filler are mixed in mixed cylinder, after airslide disintegrating mill is pulverized, mix again, can make wetting powder product of the present invention, specifically in Table 1.
Table 1 embodiment 1～18 each component and weight portion
Example 19～36 water dispersible granules
Bromuconazole, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained to the particle diameter needing through air-flow crushing together, then add other auxiliary agents such as binding agent (can add and can not add), obtain the materials of granulating.By item quantitatively send in fluidized bed granulation dryer through granulation and dry after, can make water dispersible granules product of the present invention, specifically in Table 2.
Table 2 embodiment 19～36 each component and weight portions
Example 37～54 suspending agents
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), through high speed shear, mix, add bromuconazole, active component B, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, surplus is supplied by deionized water, can make suspending agent product of the present invention, specifically in Table 3.
Table 3 embodiment 37～54 each component and weight portions
Example 55～64 suspension emulsions
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add bromuconazole, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make bromuconazole suspending agent, then by active component B, solvent, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, surplus is supplied by deionized water, make suspension emulsion product of the present invention, specifically in Table 4,5.
Table 4 embodiment 55～59 each group and weight portions
Table 5 embodiment 60～64 each group and weight portions
Example 65～76 aqueous emulsions
Bromuconazole, active component B, solvent, emulsifier are added together, make to be dissolved into even oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, become homogeneous water.Under high-speed stirred, water is added to oil phase, surplus is supplied by deionized water; Can make aqueous emulsion product of the present invention, specifically in Table 6.
Table 6 embodiment 65～76 each component and weight portions
By Fluoxastrobin, pyraclostrobin, ZJ0712, Enestroburin, kresoxim-methyl, orysastrobin, SSF 126, azoles bacterium ester interchange in table 1 ~ 6, can make novel formulation.
Example 77,78 microemulsions
Bromuconazole, active component B are dissolved in the homogenizer that solvent is housed, emulsifier, antifreeze (can add and can not add), defoamer are joined in the homogenizer that above-mentioned solution is housed, surplus gives strong mixing and homogenize after supplying by deionized water, finally obtain the as clear as crystal microemulsion product of the present invention of outward appearance.Specifically in Table 7.
Table 7 example 77,78 each component and content
Example 79,80 microcapsule suspending agents
By bromuconazole, active component B, macromolecule cyst material, solvent, make to be dissolved into even oil phase, under shearing condition, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent, dispersant, surplus is supplied by deionized water, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in Table 8.
Table 8 embodiment 79,80 each component and weight portions
Example 81,82 microcapsule suspensions-suspending agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into even oil phase, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent under shearing condition, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add bromuconazole, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make suspending agent, then suspending agent is joined in the aqueous phase solution of micro-capsule suspension, deionized water is supplied surplus, make the finely disseminated microcapsule suspension-suspending agent of present composition product, specifically in Table 9.
Table 9 embodiment 81,82 each component and weight portions
The embodiment of the present invention is the method that adopts Toxicity Determination and field trial to combine.First pass through Toxicity Determination, co-toxicity coefficient (CTC) after clear and definite two kinds of medicaments are composite by a certain percentage, CTC < 70 is antagonism, 70≤CTC≤120 are summation action, CTC > 120 is synergistic effect, on this basis, then carry out field trial.
Test method: respectively the mother liquor of each mixed agent is diluted to five series concentration during test, is placed in respectively beaker standby.Adopt and first to soak the method that connects bacterium after leaf, after the blade of the same size that does not contact any medicament is soaked to 5s in the liquid configuring, take out, naturally dry, put into bacteria box, then connect for the young bacterium of examination, under 25 ℃ of conditions, raise, every processing repeats for 3 times, every to repeat examination bacterium number used be 50, establishes blank simultaneously, in 72h, checks dead bacterium number, calculate lethality and corrected mortality, try to achieve virulence regression equation and calculate LC
50value.If contrast lethality is greater than 10%, be considered as invalid test.Computing formula is as follows:
Disease corrected mortality is converted into probit value (y), and concentration for the treatment of (μ g/ml) converts logarithm value to (x), with method of least squares, draws virulence regression equation, and calculates thus the value of every kind of medicament, according to the abundant equation of Sun Yun, calculates co-toxicity coefficient CTC.Computing formula following (take bromuconazole as standard medicament, its toxicity index is 100):
TI * the P of theoretical toxicity index (TTI)=bromuconazole of M
bromuconazoletI * P of+effective active composition B
effective active compositionb
In formula: the mixture that M is different proportionings
P
effective active compositionb is effective active composition B shared ratio in composition
P
bromuconazolefor bromuconazole shared ratio in composition
B is selected from a kind of in Fluoxastrobin, pyraclostrobin, ZJ0712, Enestroburin, kresoxim-methyl, orysastrobin, SSF 126, azoles bacterium ester.
Application Example two:
For trying disease: powdery mildew of cucumber
Test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Experimental scheme: effective lethal concentration scope of determining the former medicine of bromuconazole and Fluoxastrobin and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 10 bromuconazole and the azoxystrobin compound toxicity test analysis of results table to powdery mildew of cucumber
As shown in Table 10, bromuconazole and the Fluoxastrobin proportioning synergy ratio SR to powdery mildew of cucumber when 1 ︰ 80 ~ 80 ︰ 1 is all greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 80 ︰ 1 scopes, when the proportioning of bromuconazole and Fluoxastrobin is during at 1 ︰ 30 ~ 15 ︰ 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.10.Through applicant, test and find that the optimum ratio of bromuconazole and Fluoxastrobin is 15:1,10:1,8:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:10,1:12,1:15,1:20,1:25,1:30, especially when bromuconazole and Fluoxastrobin weight ratio are 1:2, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example three:
For trying disease: banana freckle
Test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Experimental scheme: effective inhibition concentration scope of determining the former medicine of bromuconazole and pyraclostrobin or its two different proportioning mixtures through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to banana freckle of table 11 bromuconazole and pyraclostrobin
As shown in Table 11, bromuconazole and the pyraclostrobin proportioning synergy ratio SR to banana freckle when 1 ︰ 80 ~ 80 ︰ 1 is all greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 80 ︰ 1 scopes, when the proportioning of bromuconazole and pyraclostrobin is during at 1 ︰ 30 ~ 30 ︰ 1, synergistic effect is more obviously outstanding, and synergy ratio is all more than 2.15.Through applicant, test and find that the optimum ratio of bromuconazole and pyraclostrobin is 30:1,20:1,15:1,10:1,8:1,6:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:8,1:15,1:20,1:30, especially when bromuconazole and pyraclostrobin weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example four:
For trying disease: powdery mildew of cucumber
Test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Experimental scheme: effective inhibition concentration scope of determining the former medicine of bromuconazole and ZJ0712 or its two different proportioning mixtures through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to powdery mildew of cucumber of table 12 bromuconazole and ZJ0712
As shown in Table 12, bromuconazole and the ZJ0712 proportioning synergy ratio SR to powdery mildew of cucumber when 1 ︰ 80 ~ 80 ︰ 1 is all greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 80 ︰ 1 scopes, when the proportioning of bromuconazole and ZJ0712 is during at 1 ︰ 15 ~ 30 ︰ 1, synergistic effect is more obviously outstanding, synergy ratio is all more than 2.10, and especially when bromuconazole and ZJ0712 weight ratio are 4:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example five:
For trying disease: cucumber downy mildew
Test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Experimental scheme: effective inhibition concentration scope of determining the former medicine of bromuconazole and Enestroburin or its two different proportioning mixtures through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to cucumber downy mildew of table 13 bromuconazole and Enestroburin
As shown in Table 13, bromuconazole and the Enestroburin proportioning synergy ratio SR to cucumber downy mildew when 1 ︰ 80 ~ 80 ︰ 1 is all greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 80 ︰ 1 scopes, when the proportioning of bromuconazole and Enestroburin is during at 1 ︰ 30 ~ 30 ︰ 1, synergistic effect is more obviously outstanding, synergy ratio is all more than 2.05, and especially when bromuconazole and Enestroburin weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example six:
For trying disease: pear scab
Test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Experimental scheme: effective inhibition concentration scope of determining the former medicine of bromuconazole and kresoxim-methyl or its two different proportioning mixtures through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to pear scab of table 14 bromuconazole and kresoxim-methyl
As shown in Table 14, bromuconazole and the kresoxim-methyl proportioning synergy ratio SR to pear scab when 1 ︰ 80 ~ 80 ︰ 1 is all greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 80 ︰ 1 scopes, when the proportioning of bromuconazole and kresoxim-methyl is during at 1 ︰ 30 ~ 30 ︰ 1, synergistic effect is more obviously outstanding, synergy ratio is all more than 2.10, and especially when bromuconazole and kresoxim-methyl weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example seven:
For trying disease: rice sheath blight disease
Test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Experimental scheme: effective inhibition concentration scope of determining the former medicine of bromuconazole and orysastrobin or its two different proportioning mixtures through preliminary experiment.
The composite toxicity test analysis of results table to rice sheath blight disease of table 15 bromuconazole and orysastrobin
As shown in Table 15, bromuconazole and the orysastrobin proportioning synergy ratio SR to rice sheath blight disease when 1 ︰ 80 ~ 80 ︰ 1 is all greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 80 ︰ 1 scopes, when the proportioning of bromuconazole and orysastrobin is during at 1 ︰ 30 ~ 30 ︰ 1, synergistic effect is more outstanding, synergy ratio is all more than 2.05, and especially when bromuconazole and orysastrobin weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example eight:
For trying disease: rice blast
Test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Experimental scheme: effective inhibition concentration scope of determining the former medicine of bromuconazole and SSF 126 or its two different proportioning mixtures through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to rice blast of table 16 bromuconazole and SSF 126
As shown in Table 16, bromuconazole and the SSF 126 proportioning synergy ratio SR to rice blast when 1 ︰ 80 ~ 80 ︰ 1 is all greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 80 ︰ 1 scopes, when the proportioning of bromuconazole and SSF 126 is during at 1 ︰ 30 ~ 15 ︰ 1, synergistic effect is more obviously outstanding, synergy ratio is all more than 2.10, and especially when bromuconazole and SSF 126 weight ratio are 1:4, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example nine:
For trying disease: cucumber downy mildew
Test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
Experimental scheme: effective inhibition concentration scope of determining bromuconazole and the former medicine of azoles bacterium ester or its two different proportioning mixtures through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table to cucumber downy mildew of table 17 bromuconazole and azoles bacterium ester
As shown in Table 17, bromuconazole and the azoles bacterium ester proportioning synergy ratio SR to cucumber downy mildew when 1 ︰ 80 ~ 80 ︰ 1 is all greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 80 ︰ 1 scopes, when the proportioning of bromuconazole and azoles bacterium ester is during at 1 ︰ 30 ~ 30 ︰ 1, synergistic effect is more obviously outstanding, synergy ratio is all more than 2.10, and especially when bromuconazole and azoles bacterium ester weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Through test, find: after bromuconazole and active component B are composite, the control of the powdery mildew in various crop, downy mildew, peronospora tabacina, scab, rust, epidemic disease, rice blast, banded sclerotial blight, shot hole, anthracnose, brown spot, leaf spot, net blotch, spike rot, glume blight is had to obvious synergistic effect, synergy ratio SR is all greater than 1.5.
Effect experiment part: test medicine is researched and developed, provided by Shaanxi Mei Bang agricultural chemicals Co., Ltd, contrast medicament 20% bromuconazole suspending agent (autogamy), 250 grams per liter Fluoxastrobin suspending agents (commercial), 250 grams per liter pyraclostrobin missible oil (commercial), 10% ZJ0712 suspending agent (autogamy), 25% Enestroburin missible oil (commercial), 10% kresoxim-methyl suspending agent (autogamy), 10% orysastrobin suspending agent (autogamy), 20% SSF 126 suspending agent (autogamy), 20% azoles bacterium ester suspending agent (autogamy).
Application Example ten bromuconazoles and active component B and the composite powdery mildew of cucumber test of pesticide effectiveness of preventing and treating thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation powdery mildew of cucumber disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 10 days, 20 days, 30 days.Result of the test is as follows:
Table 18 bromuconazole and active component B and the composite powdery mildew of cucumber test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 18, after bromuconazole and active component B are composite, can effectively prevent and treat powdery mildew of cucumber, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 11 bromuconazoles and active component B and the composite control tomato blight test of pesticide effectiveness thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation tomato blight disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 5 days, 15 days, 30 days.Result of the test is as follows:
Table 19 bromuconazole and active component B and the composite control tomato blight test of pesticide effectiveness thereof
As can be seen from Table 19, after bromuconazole and active component B are composite, can effectively prevent and treat tomato blight, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 12 bromuconazoles and active component B and the composite control rice blast test of pesticide effectiveness thereof
This test arrangement is in Hanzhong City suburb, Shaanxi Province, and investigation rice blast disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 10 days, 20 days, 30 days.Result of the test is as follows:
Table 20 bromuconazole and active component B and the composite control rice blast test of pesticide effectiveness thereof
As can be seen from Table 20, bromuconazole and active component B and composite control rice blast thereof, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 13 bromuconazoles and active component B and the composite wheat rust test of pesticide effectiveness of preventing and treating thereof
This test arrangement is in Weinan City Pucheng County, Shaanxi Province, and investigation wheat rust disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 3 days, 10 days, 20 days.Result of the test is as follows:
Table 21 bromuconazole and active component B and the composite wheat rust test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 21, after bromuconazole and active component B are composite, can effectively prevent and treat wheat rust, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 14 bromuconazoles and active component B and the composite control pear scab test of pesticide effectiveness thereof
This test arrangement is at Xianyang, Shanxi province suburban area, and investigation pear scab disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 3 days, 10 days, 20 days.Result of the test is as follows:
Table 22 bromuconazole and active component B and the composite control pear scab test of pesticide effectiveness thereof
As can be seen from Table 22, after bromuconazole and active component B are composite, can effectively prevent and treat pear scab, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 15 bromuconazoles and active component B and the composite downy mildew of garpe test of pesticide effectiveness of preventing and treating thereof
This test arrangement is in Weinan City Dali County, Shaanxi Province, and investigation downy mildew of garpe disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 10 days, 20 days, 45 days.Result of the test is as follows:
Table 23 bromuconazole and active component B and the composite downy mildew of garpe test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 23, after bromuconazole and active component B are composite, can effectively prevent and treat downy mildew of garpe, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 16 bromuconazoles and active component B and the composite control peronophythora litchi test of pesticide effectiveness thereof
This test arrangement is in suburb, Shantou City, Guangdong Province, and investigation peronophythora litchi disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 10 days, 20 days, 30 days.Result of the test is as follows:
Table 24 bromuconazole and active component B and the composite control peronophythora litchi test of pesticide effectiveness thereof
As can be seen from Table 24, after bromuconazole and active component B are composite, can effectively prevent and treat peronophythora litchi, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 17 bromuconazoles and active component B and the composite control Brown patch disease test of pesticide effectiveness thereof
This test arrangement is on lawn, suburb, Shaanxi Province, and investigation Brown patch disease disease index before medicine, in the dispenser of disease initial stage of origination, investigates disease indexes and calculate preventive effect for after dispenser 5 days, 10 days, 20 days.Result of the test is as follows:
Table 25 bromuconazole and active component B and the composite control Brown patch disease test of pesticide effectiveness thereof
As can be seen from Table 25, after bromuconazole and active component B are composite, can effectively prevent and treat Brown patch disease, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After through different local throughout the country tests, draw, bromuconazole and Fluoxastrobin, pyraclostrobin, ZJ0712, Enestroburin, kresoxim-methyl, orysastrobin, SSF 126, azoles bacterium ester composite rear to the preventive effect of the Common Diseases such as the powdery mildew in various crop, downy mildew, peronospora tabacina, scab, rust, epidemic disease, rice blast, banded sclerotial blight, shot hole, anthracnose, brown spot, leaf spot, net blotch, spike rot, glume blight all more than 95%, be better than single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. the bactericidal composition containing bromuconazole and methoxy acrylic, contain active components A and active component B, it is characterized in that: active components A and active component B weight ratio are 1 ︰ 80 ~ 80 ︰ 1, described active components A is selected from bromuconazole, and active component B is selected from a kind of in Fluoxastrobin, pyraclostrobin, ZJ0712, Enestroburin, kresoxim-methyl, orysastrobin, SSF 126, azoles bacterium ester.
2. the bactericidal composition containing bromuconazole and methoxy acrylic according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 60 ~ 60 ︰ 1.
3. the bactericidal composition containing bromuconazole and methoxy acrylic according to claim 2, is characterized in that:
The weight ratio of bromuconazole and Fluoxastrobin is 1 ︰ 30 ~ 15 ︰ 1;
The weight ratio of bromuconazole and pyraclostrobin is 1 ︰ 30 ~ 30 ︰ 1;
The weight ratio of bromuconazole and ZJ0712 is 1 ︰ 15 ~ 30 ︰ 1;
The weight ratio of bromuconazole and Enestroburin is 1 ︰ 30 ~ 30 ︰ 1;
The weight ratio of bromuconazole and kresoxim-methyl is 1 ︰ 30 ~ 30 ︰ 1;
The weight ratio of bromuconazole and orysastrobin is 1 ︰ 30 ~ 30 ︰ 1;
The weight ratio of bromuconazole and SSF 126 is 1 ︰ 30 ~ 15 ︰ 1;
The weight ratio of bromuconazole and azoles bacterium ester is 1 ︰ 30 ~ 30 ︰ 1.
4. according to the bactericidal composition containing bromuconazole and methoxy acrylic described in any one in claims 1 to 3, it is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspending agent.
5. the bactericidal composition containing bromuconazole and methoxy acrylic according to claim 4 is for preventing and treating the purposes of disease on crops.
6. purposes according to claim 5, is characterized in that: described disease comprises powdery mildew, downy mildew, peronospora tabacina, scab, rust, epidemic disease, rice blast, banded sclerotial blight, shot hole, anthracnose, brown spot, leaf spot, net blotch, spike rot, glume blight.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1864484A (en) * | 2005-05-18 | 2006-11-22 | 安徽华星化工股份有限公司 | Compound sterilization composition based on kresoxim methyl |
| WO2007048534A1 (en) * | 2005-10-26 | 2007-05-03 | Syngenta Participations Ag | Fungicidal compositions |
| CN101080170A (en) * | 2004-12-20 | 2007-11-28 | 巴斯福股份公司 | Method for preventing and controlling fungi disease in leguminous plants |
| CN101637157A (en) * | 2008-07-30 | 2010-02-03 | 中国中化集团公司 | Fungicide composition |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101080170A (en) * | 2004-12-20 | 2007-11-28 | 巴斯福股份公司 | Method for preventing and controlling fungi disease in leguminous plants |
| CN1864484A (en) * | 2005-05-18 | 2006-11-22 | 安徽华星化工股份有限公司 | Compound sterilization composition based on kresoxim methyl |
| WO2007048534A1 (en) * | 2005-10-26 | 2007-05-03 | Syngenta Participations Ag | Fungicidal compositions |
| CN101637157A (en) * | 2008-07-30 | 2010-02-03 | 中国中化集团公司 | Fungicide composition |
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