CN103550693A - Traditional Chinese medicine preparation for treating amenorrhea - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for treating amenorrhea. The traditional Chinese medicine preparation respectively comprises the following main raw materials in parts by weight: 5-7 parts of radix bupleuri, 3-8 parts of Chinese angelica, 2-3 parts of szechuan lovage rhizome, 1-6 parts of radix curcumae, 2-7 parts of rhizoma cyperi, 1-7 parts of salvia miltiorrhiza, 3-6 parts of red paeony root, 2-9 parts of achyranthes bidentata and 4-6 parts of motherwort. The medicines such as the radix bupleuri, the Chinese angelica, the szechuan lovage rhizome, the radix curcumae, the rhizoma cyperi, the salvia miltiorrhiza, the red paeony root, the achyranthes bidentata and the motherwort are combined, so that a synergistic effect is achieved between effects of the medicines, and the effects of soothing the liver, nourishing blood and stimulating the menstrual flow of the medicine are intensified. Therefore, the amenorrhea can be effectively treated.

Description

The Chinese medicine preparation for the treatment of amenorrhea

Technical field

The present invention relates to a kind of field of traditional Chinese for the treatment of amenorrhea, be specifically related to a kind of Chinese medicine preparation of being made by primary raw material Radix Bupleuri and other raw material of Chinese medicine compatibility.

Background technology

In prior art, amenorrhea is the common sympton of gynaecopathia, and amenorrhea reason is intricate, has the various problems such as growth, heredity, endocrine, immunity, psychological problem, also can be caused by tumor, wound and medicine factor.The foundation of normal menstrual cycle depends on the Neuroendocrine regulation between hypothalamic-pituitary-ovarian axis, and the periodic reaction of endometrium to sex gland hormones variation, therefore above-mentioned which link changes and all can cause amenorrhea, so should be for the cause of disease for diagnosis and the treatment of amenorrhea.For etiological treatment.1. congenital malformation, as atresia of hymen, atresia of vagina etc. adopt corresponding operative treatment.2. intrauterine adhesion: cervix dilating separation of synechia, can place birth control apparatus in case adhesion again.3. endometrial tuberculosis row antituberculosis therapy.4. the tumor at ovary, hypophysis and other positions, according to the position of tumor, character, size are determined suitable Therapeutic Method, excision, radiotherapy, chemotherapy etc.5. testicular feminization syndrome is androgynism, chromosome x Y, and its existing gonad has the possibility of cancerating, and answers early discovery to excise in early days.6. pair environment change, the momentary amenorrhea of psychic trauma or menophania amenorrhea in two years, can be by strengthening nutrition, health invigorating ovary development accelerating, and large multiple energies natural recovers.7. the amenorrhea that the oral contraceptive of stopping using causes recovers not need treatment mostly within half a year.8. gonadotherapy: bad to congenital gonad development, ovarian function is impaired or destruction, pituitary function exhaustion, premature ovarian failure person are applied estrogen and progestogen to stimulate secondary sex characteristics to grow, occur that menstruation sample is hemorrhage.For ovarian function, do not decline, have fertility requirement, what pituitary ovary axis still perfected can ovulation treatment.

Summary of the invention

The technical solution used in the present invention is: the Chinese medicine preparation of described treatment amenorrhea, its primary raw material and weight portion respectively, Radix Bupleuri 5-7 part, Radix Angelicae Sinensis 3-8 part, Rhizoma Chuanxiong 2-3 part, Radix Curcumae 1-6 part, Rhizoma Cyperi 2-7 part, Radix Salviae Miltiorrhizae 1-7 part, Radix Paeoniae Rubra 3-6 part, Radix Achyranthis Bidentatae 2-9 part, Herba Leonuri 4-6 part.

The present invention selects Radix Bupleuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Curcumae, Rhizoma Cyperi, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Herba Leonuri by these drug regimens, the soothing the liver function such as nourish blood, stimulate the menstrual flow that makes that each efficacy of drugs produces synergism strengthening medicine, thus can effectively treat amenorrhea.

The selected raw material of the present invention, its property of medicine and effect respectively: Radix Bupleuri: clearind deficient heat Chinese medicine, for cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus come off, menoxenia.Meridian distribution of property and flavor: cold nature, bitter in the mouth, pungent, return Liver Channel, lung meridian, spleen channel.Function: expelling pathogenic factors from the exterior expels the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.Cure mainly: cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus comes off, menoxenia.

Radix Angelicae Sinensis: [chemical composition] contains basic lactone, n-butene acyl lactone, ferulic acid, nicotinic acid, sucrose and several amino acids, and sesquiterpenoids etc.[meridian distribution of property and flavor] is warm in nature, hides sweet, pungent.Return liver, the heart, spleen channel.[function cures mainly] enriched blood and invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.

Rhizoma Chuanxiong: Rhizoma Chuanxiong, original name rhizome of chuanxiong Qiong., be usually used in blood-activating and qi-promoting, wind-expelling pain-stopping.The pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go loose, the up top, mountain peak that reaches; Enter again blood system, the descending sea of blood that reaches.Blood circulation promoting and blood stasis dispelling effect is extensive, the various diseases of suitable stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.

Flos Tulipae Gesnerianae: 1-tuliposide A, 1-tuliposide B and a small amount of Flos Tulipae Gesnerianae glycoside C that tulip contains antibacterial effect containing the two glycosides of Centaurea cyanus, salicylic acid, arginine, gynoecium, stem and leaf, 1-tuliposide A and B can partly be converted into 6-1-tuliposide A and the 6-1-tuliposide B of non-activity after placing.Bud is containing gibberellins A1.1-tuliposide A, B, C have inhibitory action to bacillus subtilis.Flos Tulipae Gesnerianae juice passes through, after cation and anion exchange resin, staphylococcus aureus to be still had to antibacterial action.The alcoholic extract of stem and leaf, has antibacterial action to Bacil lus cereus mycoides, contains several amino acids in its active component.1-tuliposide A BC has inhibitory action to bacillus subtilis.Flos Tulipae Gesnerianae juice by sun from and anion exchange resin after, staphylococcus aureus is still had to antibacterial action.The alcoholic extract of stem and leaf, has antibacterial action to Bacillus cereus mycoides, in its active component, contains several amino acids.Bulb and root also can hyoscines.Root and flower can be done tranquilizer.

Rhizoma Cyperi: the dry rhizome of sedge dried tuber.The resolving depression of regulating the flow of vital energy; Menstruction regulating and pain relieving; Antiabortive.Main distending pain over the hypochondrium; Mammary swelling is educated; Hernia pain; Menoxenia; Gastral cavity abdomen feeling of fullness pain; Belch acid regurgitation, vomiting and nausea; Abdominal pain during menstruation; Bleeding not during menses; Frequent fetal movement.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type stomachache, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.

Radix Salviae Miltiorrhizae: be dicotyledon Labiatae, dry root and rhizome.Effect: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.For costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen caking, skin infection swells and ache, tumbling down is grieved, menoxenia, amenorrhea dysmenorrhea, puerperal stasis of blood pain etc.Treatment costa sternales pain, lump in the abdomen caking, and menoxenia, amenorrhea dysmenorrhoea have good effect.Radix Salviae Miltiorrhizae can make aorta atheromatous plaque formation area obviously reduce, serum total cholesterol, triglyceride, all decreases to some degree.

Radix Paeoniae Rubra: function, clots absorbing, pain relieving, removing heat from blood, detumescence.Cure mainly: control that the stagnant amenorrhea of the stasis of blood, hernia abdominal mass gather, stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle, injury from falling down.

Radix Achyranthis Bidentatae: the dry root of amaranthaceous plant Radix Achyranthis Bidentatae Achyranthes bidentata B1..[effect] invigorating the liver and kidney; Bone and muscle strengthening; Promoting blood circulation to restore menstrual flow; Ignite (blood) descending; Inducing diuresis for treating stranguria syndrome.[curing mainly] soreness of waist and knee joint; Flaccidity and weakness of the lower limbs; Amenorrhea due to stagnation of blood; Dysmenorrhea; Puerperal abdominal pain due to blood stasis; Lump in the abdomen; Retention of placenta; Pyretic stranguria; Stranguria with blood; Traumatic injury; Carbuncle malignant boil; Laryngopharynx swelling and pain.

Herba Leonuri: promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema.Simple Herba Leonuri, because cold nature has the effect of heat-clearing and toxic substances removing, diuretic relieving constipation, truly has certain curative effect for women by the damp and hot menoxenia causing, pelvic inflammation etc., but because its strength is single, mostly coordinates other drug jointly to use.Brown sugar in Herba Leonuri paste has the effect of benefiting QI and nourishing blood, spleen invigorating warming the stomach, wind dispelling cold expelling, activating blood circulation to dissipate blood stasis.Herba Leonuri paste, because added brown sugar, has been offset the cold of Herba Leonuri, so weakened the dynamics of heat clearing away, has increased on the contrary the effect of warming uterus for dispelling cold.Therefore, for the Hypomenorrhea freely not causing because of insufficiency of vital energy and blood, part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels deficiency and coldness, blood stasis, dysmenorrhea etc., there is obvious therapeutic effect.

Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations.For example these crude drug pulverize mix homogeneously powder can be taken after mixing it with water; Can be by these crude drug together decocting, then concentrated decocting liquid is taken, or concentrated decocting liquid is condensed into cream is processed into pill and takes; In order to make each raw material of this medicine bring into play better drug effect, for certain crude drug, carry out special extraction, as ethanol extraction, these can not be for limiting the scope of the invention.Active component of the present invention can add various conventional adjuvant required while preparing different dosage form, as disintegrating agent, lubricant, binding agent etc. are prepared into any conventional peroral dosage form with conventional method of Chinese medicinal, as pill, powder, tablet, capsule, oral liquid etc.

Medicine of the present invention has promoting blood circulation to restore menstrual flow, and scattered silt pain relieving effect, is used for the treatment of amenorrhea.So far, still do not find report and the application of relevant Chinese medicine preparation of the present invention.The inventor, through research repeatedly, and by the checking repeatedly of clinical trial, has finally found the endo-medicine that has better curative effect, thereby has completed the present invention.

Specific implementation method

The Chinese medicine preparation of described treatment amenorrhea: its primary raw material and weight portion respectively, Radix Bupleuri 5-7 part, Radix Angelicae Sinensis 3-8 part, Rhizoma Chuanxiong 2-3 part, Radix Curcumae 1-6 part, Rhizoma Cyperi 2-7 part, Radix Salviae Miltiorrhizae 1-7 part, Radix Paeoniae Rubra 3-6 part, Radix Achyranthis Bidentatae 2-9 part, Herba Leonuri 4-6 part.

Claims (1)

1. a Chinese medicine preparation for the treatment of amenorrhea, it is characterized in that: its primary raw material and weight portion respectively, Radix Bupleuri 5-7 part, Radix Angelicae Sinensis 3-8 part, Rhizoma Chuanxiong 2-3 part, Radix Curcumae 1-6 part, Rhizoma Cyperi 2-7 part, Radix Salviae Miltiorrhizae 1-7 part, Radix Paeoniae Rubra 3-6 part, Radix Achyranthis Bidentatae 2-9 part, Herba Leonuri 4-6 part.