CN103537004A - Instrument for treating skin acne and skin ageing - Google Patents

Instrument for treating skin acne and skin ageing Download PDF

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CN103537004A
CN103537004A CN 201310428541 CN201310428541A CN103537004A CN 103537004 A CN103537004 A CN 103537004A CN 201310428541 CN201310428541 CN 201310428541 CN 201310428541 A CN201310428541 A CN 201310428541A CN 103537004 A CN103537004 A CN 103537004A
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skin
conductive
acne
treatment
substrate
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CN 201310428541
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Chinese (zh)
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帕特里克·米切尔·伊夫斯
杨淑如
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生物医学投资集团(香港)有限公司
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Abstract

The invention provides an instrument for treating skin acne and skin ageing. The instrument comprises a base containing liquid or a water-like substance, a conductive ring group arranged on the base and comprising one or multiple conductive rings, and a power source with one end connected with each conductive ring in the conductive ring group electrically. The instrument is simple in structure, easy to operate and low in cost.

Description

用于治疗皮肤痤疮和皮肤老化的仪器 For the treatment of skin acne and skin aging equipment

技术领域 FIELD

[0001] 本发明涉及一种医疗保健器械,具体涉及一种治疗痤疮、皮肤老化或其他类型皮肤问题的仪器。 [0001] The present invention relates to a medical care equipment, particularly relates to a method of treating the instrument acne, skin aging or other types of skin problems.

背景技术 Background technique

[0002]痤疮是最常见的皮肤病之一,在美国14~24岁的人群中,大约85%的人患有痤疮。 [0002] Acne is one of the most common skin disease in the US population 14 to 24 years of age, approximately 85% of people with acne.

[0003] 市场上大多数痤疮治疗方法的效果都没有得到临床的检验与证明。 [0003] Most of the effect on the market for acne treatment methods have not been clinically tested and proven. 唯一被临床证明能够治疗痤疮的方法是口服异维甲酸(由罗氏制药最先推向市场)。 The only way is clinically proven to treat acne is oral isotretinoin (marketed by Roche Pharmaceuticals was first). 然而,口服异维甲酸会产生多种副作用,有的副作用甚至会危及患者生命。 However, oral isotretinoin can produce a variety of side effects, some side effects and even endanger the lives of patients.

[0004] 即便痤疮已经消退,但对于患者来说,痤疮产生的疤痕依然是一个严重的问题。 [0004] Even if the acne has subsided, but for patients, acne scars generated remains a serious problem. 最常见的治疗痤疮和痤疮疤痕的方法是激光治疗和化学蜕皮。 The most common way to treat acne and acne scars is laser treatment and chemical molt. 然而,这两种治疗方法都有如下缺点:(I)费用昂贵;(2)有明显的窝工时间;(3)治疗需要经过高级专业训练的专业人士操作。 However, both treatment methods have the following disadvantages: (I) expensive; (2) a significant slowdown time; (3) treatment of high-level professionals who need to go through professional training operation.

[0005] 传统的治疗痤疮的方法,如在局部涂抹药膏对于治疗痤疮和痤疮疤痕收效甚微。 [0005] The conventional method for treating acne, such as in topical creams have little effect for treatment of acne and acne scars. 虽然许多的商品号称有极好疗效,但是所谓极好疗效并未得到证实,甚至使用其中的某些商品还有一定的危险。 While many commodities claims to have excellent efficacy, but the so-called excellent efficacy has not been confirmed, and even use of certain dangerous goods as well as some of them.

[0006] 因此,临床上急需一种预防和治疗痤疮和痤疮疤痕等皮肤问题的仪器。 [0006] Therefore, an urgent need for the prevention and treatment of skin problems, acne and acne scars and other clinical instruments.

发明内容 SUMMARY

[0007] 本发明的目的就是提供一种便捷的用于治疗皮肤痤疮和皮肤老化的仪器。 Objective [0007] The present invention is to provide a convenient for treatment of skin acne and skin aging equipment.

[0008] 本发明的治疗皮肤痤疮和皮肤老化的仪器,包括: [0008] The treatment of skin acne and skin aging device according to the present invention, comprising:

[0009] 一含有液态或水状物的基底; [0009] or a water-like liquid containing the substrate;

[0010] 设置在基底上表面的的导电环组,所述导电环组包括一个或多个导电环; Conductive ring group [0010] disposed on the substrate surface, said conductive ring group comprising one or more conductive rings;

[0011] —电源,其一端与导电环组中的每一导电环电连接。 [0011] - power supply, one end of each conductive ring is electrically conductive connected to a ring group.

[0012] 所述基底为圆形,各导电环均与基底同心。 The [0012] substrate is a circular shape, each of the conductive rings are concentric with the substrate.

[0013] 所述基底包括一吸水层和一粘贴层,所述粘贴层构成基底的下表面。 [0013] The substrate comprises a water-absorbing layer and an adhesive layer, the adhesive layer constituting the lower surface of the substrate.

[0014] 所述仪器还包括非导电环,位于所述导电环组中的相邻两导电环之间。 [0014] The apparatus further comprises a non-conductive ring, conductive rings located between adjacent two of the conductive ring group.

[0015] 所述仪器还包括一个位于所述圆形基底与所述导电环组中每一导电环之间圆形的中间层。 The [0015] apparatus further comprises a circular base located at the circular intermediate layer between each conductive loop of the conductive ring group. 所述圆形的中间层由比所述导电环组的传导性能差的材料制成。 The circular intermediate layer made of a material inferior to the conductivity of the conductive ring group. 所述圆形的中间层是由导电橡胶,氯化银、导电水凝胶,导电油墨,或导电胶粘剂制成。 The circular intermediate layer is made of conductive rubber, silver chloride, conductive hydrogel, a conductive ink or conductive adhesive. 所述圆形的中间层有一通孔,优选地,所述通孔与所述基底同心。 Said intermediate layer has a circular through holes, preferably the through hole concentric with said substrate.

[0016] 各导电环均具有独立控制的电流。 [0016] Each conductive loop has an independent control of the current.

[0017] 所述液态或者水状物是盐水或水。 The [0017] liquid or substance is water or saline water.

[0018] 所述电源是交流电源或者直流电源。 [0018] The power source is a DC power or AC power.

[0019] 所述仪器还包括一个检测基底的酸碱度的PH传感器,一个与PH传感器相连的控制器,根据所述PH传感器提供的酸碱度值,所述控制器控制所述导电环组中每一导电环的电流强度。 [0019] The apparatus further comprises a pH sensor for detecting the PH of the substrate, a controller connected to the sensor PH, PH The pH value of the sensors, the controller controls the conductivity of each conductive ring group the current strength of the rings.

[0020] 所述圆形基底还含生物试剂或化学试剂。 The [0020] circular base further comprising a biological agent or chemical agents.

[0021] 所述化学试剂或生物试剂选自抗菌药剂、消炎剂、皮脂复原剂和毛孔清洗剂的一种或多种。 [0021] The chemical or biological agent selected from one or more anti-bacterial agents, anti-inflammatory agents, sebum and pore cleaning agent recovery agent.

[0022] 已经发现,电离子导入皮肤贴片有助于提供一个可控的适于治疗如痤疮或皱纹等皮肤问题的酸性或碱性环境。 [0022] It has been found, iontophoresis dermal patch adapted to help provide a controlled, such as acne or wrinkle treating skin problems acidic or basic environment. 电离子导入仪器产生的电流分解水,且根据电流方向不同创建一个局部酸性或碱性环境。 Iontophoresis current generated by the instrument decomposition of water, and to create a different partial acidic or basic environment, according to the current direction. 角质层的酸性环境能增强真皮组织的再生。 The acid environment of the stratum corneum can enhance the regeneration of dermal tissue.

[0023] 研究发现,在持续电流作用下,角质层能被部分祛除,适于治疗包括痤疮在内的各种皮肤问题的化学药剂的经皮渗透能因角质层的祛除得到显著加强。 [0023] found that in the continuous current is applied, the stratum corneum can eliminate part, adapted to treat a variety of skin conditions including acne, including chemical agents transdermal permeation can be significantly strengthened due to eliminate the stratum corneum.

[0024] 本发明提供的仪器是一种皮肤贴片型的便携式电子仪器,在皮肤患处产生酸性或碱性环境,通过电流作用,增强皮肤药物的经皮渗透,有助于抗菌,消炎,减少皮脂(如异维甲酸)和清洗毛孔,并产生温和的化学脱皮效果。 [0024] The apparatus of the present invention is to provide a skin patch-type portable electronic device, generating an acidic or basic environment in the affected area of ​​skin by the action of the current, to enhance skin penetration of drugs transdermally, contribute antibacterial, anti-inflammatory, reduces sebum (e.g. isotretinoin) and washed pores and produce a mild chemical peeling effect.

[0025] 本发明仪器还可在皮肤上形成一个大体均匀的电流分布,克服现有的边界效应,避免现有技术中因边缘效应而出现的皮肤灼伤和治疗不足问题。 Instrument invention [0025] may also be present to form a substantially uniform current distribution on the skin, to overcome the existing boundary effects, inadequate treatment of skin burns and avoid problems of the prior art due to edge effects occur.

[0026] 另外,本发明仪器结构简单,易于操作,成本低廉。 [0026] Further, the apparatus of the present invention, the structure is simple, easy operation and low cost.

附图说明 BRIEF DESCRIPTION

[0027] 图1是本发明仪器的结构示意图 [0027] FIG. 1 is a schematic view of the apparatus of the present invention

[0028] 图2是沿图1的仪器上表面任一对称轴方向的剖视图 [0028] FIG. 2 is a cross-sectional view of the upper surface of the instrument of FIG. 1 along a symmetry axis of any

[0029] 图3是使用本发明仪器治疗皮肤问题的示意图 Schematic [0029] FIG 3 using the apparatus of the present invention is the treatment of skin problems

[0030] 其中 [0030] in which

[0031] [0031]

101-基底 102-导电环 A conductive base ring 101 102-

103-中间层 104-吸水层 An intermediate layer of absorbent layer 103- 104-

105-粘贴层 106-通孔 105- 106- adhesive layer vias

110-导电环组 111-电线 110- 111- conductive loop wire group

112-开关 115-电源 Power switch 115- 112-

116-另一皮肤位置 120-人体 116- 120- position other human skin

具体实施方式 Detailed ways

[0032]下面结合附图,对本发明进行详细说明,以使本领域技术人员更为清楚本发明的技术内容。 [0032] DRAWINGS The present invention will be described in detail to enable those skilled in the art more clearly the technical content of the present invention.

[0033] 如图1所示,为一种形式的本发明的治疗痤疮和皮肤老化的电子仪器,包括一个圆形的基底101 (可以理解,圆形只是一种形式),在基底101上表面有由一个或多个导电环102组成的导电环组110,导电环102之间的间距均匀,且是同心的,且各导电环102还与圆形基底101同心。 [0033] 1, for the treatment of acne and skin aging electronic apparatus of the present invention is a form including a circular base 101 (will be appreciated, only a circular form), on the surface of the substrate 101 a conductive ring 110 by a set of one or more conductive rings 102, the spacing between the conductive ring 102 uniform and concentric, and each conductive ring 102 is also concentric with the circular base 101. 导电环的数目范围不限,可以为I~100,本实施例为3个。 Any range of numbers conductive loop, may be I ~ 100, in this embodiment three. [0034] 各导电环102都通过电线111与电源115的一个末端(如左端所示)相连。 [0034] Each conductive ring 102 through 111 with one end (left end as shown) is connected to the power wire 115. 电源115的这一末端可选择性地设置一控制电流的开关112。 The power supply terminal 115 is disposed selectively switch a control current of 112. 导电环102与电源115的正极或者负极相连均可。 Conductive ring 102 and the positive power supply 115 is connected to the negative electrode or can.

[0035] 任何导电材料都可以用来制作导电环102,例如可以用印刷用银或铜丝作为制作导电环的材料,当然也可以用任何已知的其它导电材料制作导电环。 [0035] Any electrically conductive material may be used to make a conductive ring 102, for example by printing with silver or copper as a conductive loop material may of course be any other conductive material known in the production of conductive rings.

[0036] 基底101含液态或水状物,可以是任何已知的对于人类或动物皮肤安全的物质,本实施例选用盐水,当然,也可以为水。 [0036] The substrate 101 containing a liquid substance or water, may be any known to those of human or animal skin safe substance, the present embodiment selection brine embodiment, of course, also be water.

[0037] 基底101内含化学试剂或生物试剂,能经皮渗透,提高皮肤贴片的治疗效果。 [0037] The substrate 101 containing chemical or biological agents, skin penetration can enhance the therapeutic effect of a skin patch. 化学试剂或生物制剂可以是抗菌药剂、消炎剂、皮脂复原剂或毛孔清洁剂的一种或多种。 Chemical or biological agent may be one or more anti-bacterial agents, anti-inflammatory agents, sebum recovery agent or pore cleaners.

[0038] 抗菌药剂、消炎剂、皮脂复原剂、毛孔清洁剂的组分对于本领域技术人员而言是公知的。 [0038] anti-bacterial agents, anti-inflammatory agents, sebum recovery agent, pore cleansing agent component to those skilled in the art are well known. 例如:异维甲酸是一种适合于传送到皮肤的皮脂复原剂;烟酰胺、萘普生、布洛芬和可的松是消炎剂;过氧化苯甲酰、红霉素、克林霉素、四环素是抗菌药剂。 For example: isotretinoin is suitable to transfer to the skin sebum recovery agent; niacinamide, naproxen, ibuprofen, and anti-inflammatory agent is hydrocortisone; benzoyl peroxide, erythromycin, clindamycin , tetracycline antibacterial agents.

[0039] 电源115能提供一个恒定直流电流,一个交流电流或者一个维持特定PH值或温度或阻抗的程控电流。 [0039] The power supply 115 can provide a constant DC current, an AC current, or maintain a particular temperature PH value or programmable current or impedance.

[0040] 基底101的尺寸可根据需要调整,直径范围是2~15厘米,基底的吸水层104 (含液态或水状物)厚度在I毫米到10毫米之间。 [0040] The size of the substrate 101 can be adjusted as required, a diameter ranging from 2 to 15 cm, water-absorbing layer 104 of the substrate (liquid or water-containing substance) in a thickness of between I to 10 mm.

[0041] 本发明仪器还可包括非导电环(未图示)。 Instrument invention [0041] This may further comprise a non-conductive ring (not shown). 非导电环在导电环组中的两个相邻的导电环之间,以隔离相邻导电环。 Between two non-conductive in the conductive rings of a ring group adjacent conductive rings to isolate the adjacent conductive ring. 非导电环可用非导电橡胶制造。 A non-conductive rubber ring nonconductive available.

[0042] 导电环组中的每个导电环102都有独立控制的电流,串联控制或者并联控制均可。 [0042] The current conductive ring group each conductive ring 102 are independently controlled, the control can be connected in series or in parallel controls. 各导电环102的电流强度相等。 Equal to the current strength of each conductive ring 102.

[0043] 本发明的导电环102均匀分布和强度相同,利于形成均匀的电流分布。 [0043] The present invention is the same as the conductive ring 102 and a uniform intensity distribution, a uniform distribution of current beneficial.

[0044] 本发明仪器还包括一个PH传感器,它可以检测基底101的PH值。 [0044] The apparatus of the present invention further comprises a PH sensor that can detect the PH value of the base 101. 还包括一个与PH传感器相连的控制器。 Further comprising a controller connected to a PH sensor. 根据PH传感器检测到的PH值,控制器控制导电环组中的各导电环102的电流。 The PH PH value detected by the sensor, the controller each conductive current conductive rings 102 in the control group.

[0045] 本发明仪器可在皮肤上创造一个局部的酸性或者碱性的环境,从而可以用于治疗皮肤病。 Instrument invention [0045] This may create a partial acidic or basic environment on the skin, it can be used to treat skin diseases.

[0046] 使用本发明仪器治疗皮肤问题的步骤为: [0046] To use the apparatus of the invention for the treatment of skin problems:

[0047] (I)将基底101的粘贴层105与皮肤患处相接触,粘附在皮肤患处; [0047] (I) The adhesive layer 105 of the substrate 101 in contact with the affected area of ​​skin, the skin adhered to the affected area;

[0048] (2)通过电线将所述电源115的另一端与另一皮肤位置116相连; [0048] (2) connected by wire to the other end of the power supply 115 with another skin location 116;

[0049] (3)持续施加由电源115提供的电流后,直到在所述皮肤患处区域形成一个酸性或者碱性的环境。 After [0049] (3) for applying a current provided by the power 115, a form of acidic or basic environment until the affected area of ​​skin area.

[0050] 以上步骤还可以用来化学换肤或者治疗类似痤疮的皮肤病。 [0050] The above steps can also be used to treat similar or chemical peels acne skin disease. 进一步地,通过这种方法产生的酸也能被用来祛除皱纹或者皮肤色斑。 Further, the acid produced by this method can also be used to eliminate wrinkles or skin pigmentation.

[0051] 如图2所示,为沿图1的仪器上表面任一对称轴方向的剖视图,基底101有一个粘贴层105和一吸水层104,该粘贴层105有一个与基底101同心的通孔106,以便形成施药通道,并一定程度上容纳皮肤的凸起部分。 [0051] 2, a cross-sectional view of a symmetry axis of the instrument of FIG. 1 along any surface, a substrate 101 has an adhesive layer 105 and absorbent layer 104, the adhesive layer 105 and the substrate 101 has a concentric through hole 106, so as to form a channel of administration, and receiving the convex portion of the skin to some extent. 吸水层容纳液态或水状物,吸收化学或生物试剂。 Water-absorbing layer containing a liquid substance or water-absorbent chemical or biological agent. 粘贴层105能把仪器贴附在皮肤上,从而使本发明仪器为皮肤贴片型仪器。 Adhesive layer 105 applied to the skin can instrument, so that the apparatus of the invention is a skin patch-type device. 中间层103位于导电环组中每一导电环102与基底101之间,中间层103由比导电环传导性弱的材料所制成,如导电橡胶,氯化银,导电水凝胶,导电油墨或者导电胶粘剂,起到缓冲作用。 The intermediate layer 103 between the conductive ring group each of the conductive ring 102 and the substrate 101, intermediate layer 103 made of a material weaker than the conductivity of the conductive ring, such as a conductive rubber, silver chloride, conductive hydrogels, or conductive ink conductive adhesive, cushion. [0052] 如图3所示,基底101通过粘贴层105贴在一个人体120的皮肤患处,通过一根或多根电线111,导电环组中每一导电环102均与电源115相连。 [0052] 3, base 101 by adhesive layer 105 on the body 120 of a skin lesion, by one or more wires 111, a conductive ring group each conductive loop 102 are connected to the power supply 115. 电源115的另一端是与人体的另一皮肤区域116直接连接。 The other end of the power supply 115 is directly connected to the other skin areas of the body 116. 区域116可以是人体的任何位置,优选地,区域116至少离患处I英寸,或者2英寸,或者3英寸,或者4英寸,或者5英寸,或者10英寸,或者20英寸,或者30英寸,或者50英寸,以减小边界效应造成的不利影响。 Region 116 may be any body position, preferably, the region 116 from at least the affected area I inch or 2 inches or 3 inches, or 4 inches, or 5 inches, or 10 inches, or 20 inches, or 30 inches, or 50 inches, in order to reduce the adverse effects caused by boundary effects.

[0053] 根据皮肤类型和治疗目的,采用实验方法能确定形成一个酸性或碱性的环境的时间。 [0053] The skin type and therapeutic purposes, can be determined experimentally using time environment formed in a acidic or basic. 一般而言,形成一个酸性或碱性的环境大约需要10分钟到10小时。 Generally, a form of acidic or basic environment takes about 10 minutes to 10 hours.

[0054] 当一个酸性或碱性的环境在皮肤上形成,角质层可以部分或彻底祛除。 [0054] When an acidic or alkaline environment is formed on the skin, the stratum corneum may be partially or completely eliminate. 角质层部分或完全祛除后,仪器自动关闭,然后让基底101中吸水层容纳的被动扩散的药剂经皮渗透,发挥后续作用。 After the stratum corneum partially or completely eliminate, the instrument automatically shut down, and let the agent transdermal passive diffusion substrate 101 accommodated in the permeate water-absorbing layer, the subsequent play a role.

[0055] 在治疗之前,可以用一个酒精垫来清洁患处,也可用低浓度的丙酮垫来清洁患处。 [0055] Prior to treatment, the alcohol may be a pad for cleaning the affected area, a low concentration can also be used to clean the affected area of ​​the pad with acetone. 丙酮垫有助于祛除部分角质层和增强治疗药剂的经皮渗透。 Acetone pad and helps to eliminate part of the stratum corneum to enhance transdermal permeation of therapeutic agents.

[0056] 虽然在此公开了各种具体技术信息,但是仅是为了说明,并不能限制保护范围,本发明的保护范围以权利要求书的内容为准。 [0056] Although disclosed herein in various specific technical information, but merely to illustrate and not limit the scope, the scope of the present invention in the claims and their equivalents.

Claims (10)

  1. 1.一种治疗皮肤痤疮和皮肤老化的仪器,包括: 一含有液态或水状物的基底; 设置在所述基底上的导电环组,包括一个或多个导电环; 一电源,其一端与所述导电环组中的每一导电环电连接。 1. A method of treating skin acne and skin aging apparatus, comprising: a water containing liquid or a substrate substance; disposed on the substrate conductive ring group comprising one or more conductive rings; a power supply having one end each of the electrically conductive loop is connected to the conductive ring group.
  2. 2.如权利要求1所述的治疗皮肤痤疮和皮肤老化的仪器,其特征在于:所述基底为圆形,各导电环均与基底同心。 2. The treatment of skin acne and skin aging device according to claim 1, wherein: said substrate is circular, each of the conductive rings are concentric with the substrate.
  3. 3.如权利要求1所述的治疗皮肤痤疮和皮肤老化的仪器,其特征在于:还包括非导电环,位于所述导电环组中的相邻两个导电环之间。 Treatment of skin acne and skin aging device according to claim 1, characterized in that: further comprising a non-conductive ring between two adjacent conductive ring located between the conductive ring group.
  4. 4.如权利要求1所述的治疗皮肤痤疮和皮肤老化的仪器,其特征在于:各导电环均具有独立控制的电流。 Treatment of skin acne and skin aging of the apparatus as claimed in claim 1, wherein: each of the conductive loop has an independent control of the current.
  5. 5.如权利要求4所述的治疗皮肤痤疮和皮肤老化的仪器,其特征在于:还包括一个检测基底的酸碱度用的PH传感器,一个与PH传感器相连的控制器,根据所述PH传感器提供的酸碱度值,所述控制器控制各导电环的电流强度。 5. The treatment of skin acne and skin aging device according to claim 4, characterized in that: further comprising a pH detecting sensors PH with the substrate, and a controller connected to the sensors PH provided according to the PH sensor pH value, the controller controls a current intensity of each conductive loop.
  6. 6.如权利要求2所述的治疗皮肤痤疮和皮肤老化的仪器,其特征在于:还包括一个位于所述圆形基底与所述导电环组之间的圆形中间层。 6. The treatment of skin acne and skin aging device according to claim 2, characterized in that: further comprising a circular intermediate layer positioned between said substrate and said conductive circular ring group.
  7. 7.如权利要求6所述的治疗皮肤痤疮和皮肤老化的仪器,其特征在于:所述圆形中间层由比所述导电环组的传导性能差的材料制成,所述材料包括导电橡胶,氯化银、导电水凝胶,导电油墨,或导电胶粘剂。 7. The treatment of skin acne and skin aging device according to claim 6, wherein: said circular intermediate layer is made of a material inferior to the conductivity of the conductive ring group, said material comprising a conductive rubber, silver chloride, conductive hydrogel, a conductive ink or conductive adhesive.
  8. 8.如权利要求1所述的治疗皮肤痤疮和皮肤老化的仪器,其特征在于:所述基底内含生物试剂或者化学试剂。 8. The treatment of skin acne and skin aging device according to claim 1, wherein: said substrate reagent containing biological or chemical agents.
  9. 9.如权利要求8所述的治疗皮肤痤疮和皮肤老化的仪器,其特征在于:所述化学试剂或生物试剂选自抗菌药剂、消炎剂、皮脂复原剂和毛孔清洗剂的一种或多种。 9. the treatment of skin acne and skin aging device according to claim 8, wherein: said chemical or biological agent an agent selected from an antibacterial, anti-inflammatory agents, sebum recovery agent or cleaning agent and pores more .
  10. 10.如权利要求1所述的治疗皮肤痤疮和皮肤老化的仪器,其特征在于:所述基底包括一粘贴层和一吸水层。 10. The treatment of skin acne and skin aging device according to claim 1, wherein: said substrate comprises an adhesive layer and a water-absorbing layer.
CN 201310428541 2013-09-18 2013-09-18 Instrument for treating skin acne and skin ageing CN103537004A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1133743A (en) * 1995-04-18 1996-10-23 李培基 Master and secondary integrated therapy electrodes
US20040267189A1 (en) * 2001-10-24 2004-12-30 Daniela Mavor Device and method for controlled delivery of active substance into the skin
CN1832776A (en) * 2003-06-30 2006-09-13 强生消费者公司 Device for treatment of human or animal barrier membranes
CN101198373A (en) * 2005-04-22 2008-06-11 埃克庞特医疗公司 DC tissue treatment

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1133743A (en) * 1995-04-18 1996-10-23 李培基 Master and secondary integrated therapy electrodes
US20040267189A1 (en) * 2001-10-24 2004-12-30 Daniela Mavor Device and method for controlled delivery of active substance into the skin
CN1832776A (en) * 2003-06-30 2006-09-13 强生消费者公司 Device for treatment of human or animal barrier membranes
CN101198373A (en) * 2005-04-22 2008-06-11 埃克庞特医疗公司 DC tissue treatment

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